INTEGRAL UNIVERSITY,

LUCKNOW

SYLLABUS
&
EVALUATION SCHEME

for

B.Tech. Biomedical Engineering

2nd Year
(with effect from 2019-20)
 STUDY & EVALUATION SCHEME
B. Tech. Biomedical Engineering
(w.e.f.- July 2019)

2nd Year 3rd

Semester

Cours Name Evalu

Subje
e of the Perio ation
Sl. No ct
Categ Subje ds Sche
Code
ory ct me
Sub.
Sessio Total
nal
(CA)
L T P C CT TA Total
Funda
menta (ESE)
l of
EC23
1. DC* Biome 3 1 0 4 25 15 40 60 100
1
dical
Electr
onics
Funda
menta
ls of
EC23 Circui
2. DC* 3 1 0 4 25 15 40 60 100
2 ts
and
Netwo
rks
Biome
dical
Senso
BE27
3. DC rs and 2 1 0 3 25 15 40 60 100
1
Measu
remen
t
Huma
n
Anato
my
BE27 and
4 DC 3 1 0 4 25 15 40 60 100
2 Physi
ology
for
Engin
eers
5. ESA CS20 Cyber 2 1 0 3 25 15 40 60 100
 Law
&
Infor
3 matio
n
Securi
ty
Bioch
emical
Analy
sis
and
BE27 Techn
6 DC 3 1 0 4 25 15 40 60 100
3 iques
Analy
sis
and
Techn
iques
Disast
er
7. ESA ES202 Mana 2 1 - 3 25 15 40 60 100
gemen
t
Huma
n
Value
BM22
8. HM s& 3 - - - - - - 50** 50**
6
Profes
sional
Ethics
Practicals
Huma
n
Anato
my
BE27 0 0
9. DC and 2 1 30 30 60 40 100
4
physio
logy
Lab

Electr
EC23 onics 0 0
10. DC* 2 1 30 30 60 40 100
3 Circui
ts Lab
Senso
r and
EC23 0 0
11. DC* measu 2 1 30 30 60 40 100
4
remen
t Lab
Total 21 7 10 28 265 195 460 540 1000
* An inter-disciplinary program offered by the Department of Bioengineering in association with the Department
of Electronics and Communication Engineering.
**A non-credit foundation course. Candidate has to pass the course by securing at least 50 % marks up to fourth
semester

L – Lecture T – Tutorial P – Practical C – Credits CT – Class Test TA – Teacher

Assessment
Sessional Total (CA) = Class Test + Teacher Assessment
Subject Total = Sessional Total (CA) + End Semester Examination (ESE)
BS – Basic Sciences, DC – Departmental Core, HM – Humanities, OE – Open Elective, DE – Departmental
Elective,
ESA – Engineering Sciences & Arts (Foundation Course & Engineering Courses)

2nd Year 4th Semester

Periods Evaluation Scheme Subje

S
l. Course Subje and Sessional (ES ctTot
N Categor ct Name of the Subject Credits (CA) E) al
o y Code
C T Tot
. L T P C
T A al

1 BE27 2
DC Biomechanics 2 1 0 3 15 40 60 100
. 5 5
2 BE27 Biomedical Signals and 2
DC 3 1 0 4 15 40 60 100
. 6 Systems 5
3 EC23 Digital Logic circuits for 2
DC* 2 1 0 3 15 40 60 100
. 5 Clinical Engineers 5
4 PY20 2
ESA Medical Optics 2 1 0 3 15 40 60 100
. 6 5
5 EC23 Integrated Circuit for 2
DC* 3 1 0 4 15 40 60 100
. 6 Bioinstrumentation 5
6 BE27 Biomaterials and Artificial 2
DC 2 1 0 3 15 40 60 100
. 7 Organs 5
Principles of Management, 2
7 BM22
ESA Industrial Economics & 2 1 0 3 15 40 60 100
. 9 5
IPR
Practicals
8 DC* EC23 Digital logic Lab 0 0 2 1 3 30 60 40 100
 . 7 0
9 EC23 3
DC* Bio instrumentation Lab 0 0 2 1 30 60 40 100
. 8 0
1
BE27 3
0 DC Electro therapy Lab 0 0 2 1 30 60 40 100
8 0
.
2
1 2 19
Total 7 6 6 460 540 1000
6 6 5
5

* An inter-disciplinary program offered by the Department of Bioengineering in association with

the Department of Electronics and Communication Engineering.

L – Lecture T – Tutorial P – Practical C – Credits CT – Class Test TA –

Teacher Assessment
Sessional Total (CA) = Class Test + Teacher Assessment
Subject Total = Sessional Total (CA) + End Semester Examination (ESE)
BS – Basic Sciences, DC – Departmental Core, HM – Humanities, OE – Open Elective, DE –
Departmental Elective,
ESA – Engineering Sciences & Arts (Foundation Course & Engineering Courses)
 FUNDAMENTAL OF BIOMEDICAL ELECTRONICS
EC231

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: To introduce the basics of various electronic components used

for the construction of medical devices.
UNIT I Diodes 8
Review of PN Junction Diode- characteristics and application
Special purpose diodes: Tunnel diode, Varactor Diode, Schottkey Diode,
Light Emitting Diode, Laser Diode and photo voltaic cell, with their
working principle and characteristics.

UNIT II Bipolar Junction Transistor 8

Review of Configuration and V I characteristics of BJT, Small signal and
low frequency analysis of BJT amplifier,
Darlington pair, cascode amplifier
Classification of Amplifiers: Class A,B,C amplifiers, Audio Amplifiers,
Power amplifier.
UNIT III MOSFET : 8
Review of device structure, operation & V I characteristic. Ohmic and
saturation region equations.
Classification of MOS (NMOS, PMOS, CMOS) principle of working and
comparison,
MOSFET as an amplifier and switch, biasing of MOS amplifier circuit, CS,
CG, CD configuration using NMOS, frequency response of a single stage
CS amplifier.
UNIT IV Feedback Amplifiers: 8
Basic concept of feedback, General Characteristics of negative feedback
amplifiers, Classification of feedback, Voltage/Current shunt and series
feedback, stability of feedback amplifiers, Multistage Amplifiers.
UNIT V Oscillators & Voltage Regulator Oscillators; 8
Condition for oscillation, generalized form of oscillator circuit, The phase
shift oscillator, Hartley & Colpitt‟s oscillator. The Wein Bridge oscillator,
Crystal oscillator, frequency stability. Regulated Power Supplies:
SMPS,UPS ( block diagram).

Books Recommended:
1. Millman & Halkias/ Integrated Electronics / McGraw-Hill Education India.
2. Sedra, and Smith,/ Microelectronic Circuits/ Oxford University Press India/ 5th Edition.
3. Diffenderfer Robert/Electronic Devices: Systems and Applications/Cengage Learning.
Reference materials:
1. Shilling & Belove/ Electronic Circuit/ McGraw-Hill Education India.
2. Streetman, B.G. Banerjee, Sanjay/ Solid State Electronic Devices/ PHI.
3. Salivahanan, Kumar, Suresh & Vallavraj/ Electronic Devices & Circuits/ McGraw-Hill
Education India.
 FUNDAMENTAL OF CIRCUITS AND NETWORKS
EC-232
(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: To enable the students to acquire knowledge about the basics of circuit
analysis, network theorems and AC circuits.

UNIT I Introduction 8
Review of D.C. & A.C. circuits, DC Circuits: Current & Voltage
Source Transformation.
Mesh & Node Analysis of D.C., concept of network, active and
passive network

UNIT II Network Theorem 8

Superposition Theorem, Thevenin‘s Theorem, Norton‘s Theorem,
Maximum Power Transfer Theorem, Millman's Theorem, Tellegen's
Theorem , Dual & Duality
UNIT III Circuit Analysis 8
Introduction to Graph Theory. Tree, link currents, branch voltages,
cut set & tie set, Mesh & Node Analysis
UNIT IV Time and Frequency Response of Circuits: 8
First & second order Differential equations, initial conditions.
Evaluation & Analysis of Transient Steady state responses using
Classical Technique as well as by Laplace Transform (for simple
circuits only). Transfer function, Concept of poles and zeros.
UNIT V Two-Port Networks: 8
Concept of two-port network. Driving point and Transfer Functions,
Open Circuit impedance (Z) parameters, Short Circuit admittance
(Y) parameters, Transmission (ABCD) parameters. Inverse
Transmission (A‘B‘C‘D‘) parameters. Hybrid (h) parameters. Inter
Relationship of different parameters. Interconnections of two-port
networks.

Books Recommended:
1. Sudhakar & S.P. Shyammohan, Circuits and Networks, Tata McGraw Hill, thirteenth
reprint, 2000.
2. William H. Hayt, Jack e. Kemmerly & Steven M. Durbin, Engineering Circuit Analysis,
McGraw Hill International, sixth edition, 2202.
3. Raymond A. DeCarlo & Pen-Min Lin, Linear Circuit Analysis, Oxford University Press,
second edition, 2001.
 BIOMEDICAL SENSORS AND MEASUREMENT
BE271
(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: To impart adequate knowledge about the sensors and measuring instruments used
for measurement and detection of physical quantities.

UNIT I Standards and Measuring errors 8

Scientific notations and metric prefixes. SI electrical units, SI
temperature scales, Other unit systems, dimensions and standards.
Measurement Errors: Gross error, systematic error, absolute error
and relative error, accuracy, precision, resolution and significant
figures, Measurement error combination,
PMMC instrument, Galvanometer, Conversion to ammeter and
voltmeter
UNIT II Transducer 8
Classification of transducers and characteristics for selection of
transducers, Resistive transducers, Inductive transducers, Capacitive
transducers, Piezoelectric effect transducer, Thermoelectric
Transducers
UNIT III Multimeter and CRO 8
Digital voltmeter systems, Digital multimeter
CRT, Wave Form Display, Time Base, Dual Trace Oscilloscope,
measurement of voltage, frequency and phase by CRO, DSO, DSO
applications.
UNIT IV Medical Applications of Sensors: 8
Biosensors: Principles and, classification, Optical biosensors for
measurement of blood glucose level, Smart sensor, Electronic nose.

Books Recommended:
1. David A. Bell, “Electronic Instrumentation and Measurements”, Oxford University
Press
2. Sawhney A.K, “A Course in electrical and electronic measurements and
instrumentation”, DhanpatRai & Co (P) Ltd, Educational and Technical Publishers,
19th Revised edition 2011
Reference materials:
1. Patranabis D, “Sensors and transducers”, PHI, 2nd edition,2004.
2. R.S. Khanpur, “Handbook of Biomedical Instrumentation” Tata McGraw Hill
3. H.E. Thomas, “Handbook of Biomedical Instrumentation and Measurement” Restone
Publishing Company
HUMAN ANATOMY AND PHYSIOLOGY FOR ENGINEERS
 BE272

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: The purpose of learning this course is to provide the students a basic understanding
of the various parts of the human body, their anatomical position and their functions.
UNIT I Cell and Blood Groups 8
Structure of cell, organelles and description, function of each
component of the cell, Membrane potential, generation of action
potential, Action potential conduction, electrical stimulation, Blood
cell , composition, origin of RBC, Blood groups, estimation of RBC,
WBC and platelet count, Blood groups identification
UNIT II Cardiac and Nervous System 8
Heart, major blood vessels, cardiac cycle, blood pressure, Cardiac
output , coronary and peripheral circulation, Structure and function
of nervous tissue, neuron ,synapse, Brain, spinal cord, reflex action,
Peripheral nervous system, Autonomic nervous system,
Identification of nervous system
UNIT III Respiratory System and Musculo Skeletal System 8
Physiological aspects of respiration, Trachea and lungs, exchange of
gases, Regulation of respiration, disturbance of respiration function,
Muscles, structure of skeletal muscle, Physiology of muscular
contraction, Joints and its classification, System identification of
lung model
UNIT IV Digestive and Excretory System 8
Organization of GI system, digestion and absorption, Movements of
GI tract, intestine, Liver, pancreas, structure of nephron, Mechanism
of urine formation, urine reflex, Skin and sweat gland, temperature
regulation, Explanation of digestive system with mode
UNIT V Eye, Ear, Endocrine Glands 8
Optics of eye, retina, photochemistry of vision, accommodation,
Neurophysiology of vision, Physiology of internal ear, mechanism of
hearing, Auditory pathway, Endocrine glands,

Books Recommended:
1. SaradaSubramanyam, K.MadhavanKutty and H.D.Singh, “Text book of human physiology”,
S.Chand& Company, 5th edition, 2014.
2. Ranganathan T.S., “Text book of human anatomy”, S.Chand&Co. Ltd., Delhi, 5th edition,
2014.
Reference materials:
1. Tobin, C.E., “Basic human anatomy”, McGraw-Hill Publishing Co. Ltd., Delhi, 2nd edition,
1997
2. J.Gibson, “Modern physiology and anatomy for nurses”, Blackwell SC Publishing, 2nd edition,
1981.
3. Arthur.C.Guyton, John E Hall, “Textbook of medical physiology”, W.B. Saunders Company,
11th edition, 2000
 CYBER LAW AND INFORMATION SECURITY
CS-203
(w.e.f.- January 2017)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: The aim of the course is to enable students to understand the implications of
Information technology and the need for regulating the cyber space and the information
exchange in the information super highway.

UNIT I Fundamentals of Cyber Law: Jurisprudence of Cyber Law, Object 8

and Scope of the IT Act 2000, Introduction to Indian Cyber Law,
Unicitral Model Law, ISP Guideline. Intellectual property issues and
cyber space, Indian perspective, Overview of Intellectual property
related legislation in India, Patent, Copy Right, Trademark law, Law
related to semiconductor layout & design.

UNIT II E-Commerce: Security Threats to E-Commerce, Virtual 8

Organization, Business Transactions on Web, E-Governance and
EDI, Concepts in Electronics payment systems, E-Cash, Credit/Debit
Cards, E-Agreement, Legal recognition of electronic and
digital records, E-Commerce Issues of privacy, Wireless
Computing-Security challenges in Mobile devices. Digital
Signatures-Technical issues, legal issues, Electronic Records, Digital
Contracts, Requirements of Digital Signature System.

UNIT III Investigation and Ethics: Cyber Crime, Cyber jurisdiction, Cyber 8
crime and evidence act, Treatment of different countries of cyber
crime, Ethical issues in data and software privacy, Plagiarism,
Pornography, Tampering computer documents, Data privacy and
protection, Domain Name System, Software piracy, Issues in ethical
hacking. Internet security treats: Hacking, Cracking, Sneaking,
Viruses, Trojan horse, Malicious Code & logic bombs. Introduction
to biometric security and its challenges, Finger prints. Cyber crime
forensic: CASE STUDY in Cyber Crime.

UNIT IV Information security- Information Systems and its Importance, Role 8

of Security in Internet and Web Services, Principles of Information
Security, Classification of Threats and attacks, Security Challenges,
Security Implication for organizations, Security services-
Authentication, Confidentiality, Integrity, Availability and other
terms in Information Security, Information Classification and their
Roles. Introduction to Cryptography, Issues in Documents Security,
Keys: Public Key, Private Key, Firewalls, Basic Concepts of
 Network Security, Perimeters of Network protection & Network
attack, Need of Intrusion Monitoring and Detection.

References:
1. Harish Chander “Cyber Law and IT Protection”, PHI Publication, New Delhi.
2. Merkov, Breithaupt “Information Security”, Pearson Education.
3. “Cyber Law in India” - Farooq Ahmad-Pioneer books.
4. K. K. Singh, Akansha Singh “Information Security and Cyber law”, Umesh Publication,
Delhi.
 BIOCHEMICAL ANALYSIS AND TECHNIQUES

BE273

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: The number of conventional and modern analytical techniques along with their principle,
instrumentation and applications are included in the course.

UNIT I Basic Techniques: Buffers; Methods of cell disintegration; Enzyme assays 8

and controls; Detergents and membrane proteins; Dialysis, Ultrafiltration
and other membrane techniques.

UNIT II Chromatography: Principle, instrumentation and applications of 8

separation techniques for different biomolecules and applications:
Chromatography – paper, TLC, Gel filtration, ion exchange, affinity,
HPLC, FPLC and GC.
UNIT III Electrophoresis: Capillary electrophoresis: Principle and instrumentation. 8
Electrophoresis - gel, agarose-gel, PAGE, SDS-PAGE, Iso-electric
focusing. Immuno-electrophoresis and electroblotting and applications.
Spectroscopy: principle, instrumentation and application of UV-visible,
fluorescent, CD, NMR, ESR spectroscopy, Atomic absorption
spectroscopy, Plasma emission spectroscopy.
UNIT IV Physical techniques in structural analysis of biomolecules and 8
applications: X-ray diffraction, Mass spectroscopy. Advanced Techniques:
Protein crystallization; Theory and methods; API-electrospray and
MALDI-TOF; Mass spectrometry; Enzyme and cell immobilization
techniques; DNA & Peptide Synthesis.
UNIT V Centrifugation and Radiotracer techniques: Principle, instrumentation 8
and applications of Centrifugation and ultracentrifugation. Radioisotope
techniques - nature of radiation sources, radioactive decay, units of
radiation, detection and measurement of radioactivity, GM and scintillation
counters and autoradiography.

Books Recommended:
1. Principles of instrumental analysis. Skooge DA., Holler FJ., Crouch SR., Thompson Brooks
Publ., 1988.
2. Basic concepts of analytical chemistry. Khopkar SM. New Age International Publ. New
Delhi, 1998.
3. Principles and Techniques of Biochemistry and Molecular Biology, K. Wilson and J. Walker
(Eds.) 6th Ed., Cambridge Univ. Press, 2005.
4. D. Holme & H. Peck, Analytical Biochemistry, 3rd Edition, Longman, 1998.
5. R. Scopes, Protein Purification - Principles & Practices, 3rd Edition, Springer Verlag, 1994.
Reference materials:
1. Selected readings from Methods in Enzymology, Academic Press.
 DISASTER MANAGEMENT
ES202
(w.e.f.-Session2016-2017)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: The objective of this course is to familiarize the student with basic management
principles relating to disaster management and mitigation techniques.
UNIT I Concept of disaster management. Types of disaster and their impact: 8
Natural and Man- Made, Like- Earthquakes, Floods, Tsunami,
Droughts, Cyclones, Avalanches, Forest Fire, Terrorism related
Disaster etc. Assessment of human and Economic losses.

UNIT II Impact of extensive Industrialization. Impact of Global Warming and 8

Environmental Degradation. National and global disasters.

UNIT III National policy for disaster Management, Elementary Knowledge of 8

the Disaster Management Act 2005. Types of Responses: Central,
State, District Level, Peoples Community participation in Disaster
Management. Post-Disaster Management and Rehabilitation
measures.

UNIT IV Capacity Building for meeting disasters. Long term measures for 8
preventions of disasters. Mitigation technique/strategies: Early
warning systems, Data sharing at national and international level.

References:
1. Disaster management by Dr. V.K. Sethi.
2. The great Sumatra Earthquakes and Indian Ocean tsunami of December 2004- the effects
of main land India and in the Andaman and Nicobar Island, published by IIT Kanpur.
3. Environmental managaenet by Dr. Shakeel Ahmad.
4. Hazards, disasters and your community, ministry of home affairs.
 HUMAN VALUES & PROFESSIONAL ETHICS
BM226

Pre-requisite Co-requisite L T P C

None None 3 0 0 0

Objective: The objective of this course is to inculcate in the students ethical and moral
values and to motivate them to become good responsible professionals.

UNIT I Human Value Education 6

Understanding the need, basic guidelines, content and process for

Value Education, Self Exploration - Its content and process; ‘Natural
Acceptance’ and Experiential Validation - as the mechanism for self
exploration, Continuous Happiness and Prosperity - A look at basic
Human Aspirations, Right understanding, Relationship and Physical
Facilities- the basic requirements for fulfillment of aspirations of
every human being with their correct priority, Understanding
Happiness and Prosperity correctly.

UNIT II Introduction to Ethical Concept 6

Definition of industrial ethics and values, Ethical rules of industrial

worker. Values and Value Judgments. Moral Rights and Moral rules,
Moral character and responsibilities. Privacy, Confidentiality,
Intellectual Property and the Law. Ethics as Law.

UNIT III Professional Responsibility 6

The basis and scope of Professional Responsibility, Professions and

Norms of Professional Conduct, Ethical Standards versus Profession,
Culpable mistakes, the Autonomy of professions and codes of ethics.
Employee status and Professionalism. Central Professional
Responsibilities of Engineers: The emerging consensus on the
Responsibility for safety among engineers, hazards and risks.

UNIT IV Engineers Ethics 6

Senses of 'Engineering Ethics' - variety of moral issues - types of

inquiry - moral dilemmas - moral autonomy - Kohlberg's theory -
Gilligan's theory - consensus and controversy – Models of
Professional Roles - theories about right action - Self-interest -
customs and religion - uses of ethical theories. Valuing Time – Co-
operation – Commitment.

UNIT V Global Issues 6

A Glimpse of Life Stories: Life story of Prophet Mohammad,

 Mahatma Gandhi, Swami Vivekanand, Marie Curie and Steve Jobs.

Multinational corporations - Environmental ethics - computer ethics -

weapons development - engineers as managers-consulting engineers-
engineers as expert witnesses and advisors -moral leadership.

Reference Readings:
Text Book:
1. R. R. Gaur, R Sangal, G. P. Bagaria, 2009, A Foundation Course in Value Education.
2. Mike Martin and Roland Schinzinger, “Ethics in Engineering”, McGraw-Hill, New York
1996.
3. Govindarajan M, Natarajan S, Senthil Kumar V. S, “Engineering Ethics”, Prentice Hall of
India, New Delhi, 2004.
Relevant CDs, Movies, Documentaries & Other Literature:
1. Value Education website, http://www.uptu.ac.in.
2. Story of Stuff, http://www.storyofstuff.com
3. Al Gore, An Inconvenient Truth, Paramount Classics, USA.
4. Charlie Chaplin, Modern Times, United Artists, USA.
5. IIT Delhi, Modern Technology – the Untold Story.
6. The Hundred, Michael Hart.
 HUMAN ANATOMY AND PHYSIOLOGY LAB
BE274
(w.e.f. session 2015-2016)

Pre-requisite Co-requisite L T P C

None None 0 0 2 1

Objective: To attain expertise in identification of various parts and components of human

skeleton.

List of Experiments

1. Identification of all the long and small bones, different joints, skull, jaw and facial
bones in human skeleton.
2. Study of human eye and ears with help of 3D model.
3. Identification of respiratory passage components and various lobes of Human lungs.
4. Study of human kidney with the help of 3 D model.
5. Study of blood cells, their morphological identification and counting.
6. Study of human blood groups.
7. Preparation of slides of various tissues (epithelial, connective) and their microscopic
study.
 BIOMECHANICS

BE275

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: The purpose of learning this course is to acquire knowledge and understand the
basic mechanical concepts involved in human movement

UNIT I Kinematic and Kinetic Concepts of Human Motion 8

Introduction, forms of motion, standard reference terminology, joint
movement terminology, Spatial reference systems, qualitative
analysis of human movement, tools for measuring kinematic
quantities, Basic concepts related to kinetics, mechanical loads on
the human body, Effects of loading, tools for measuring kinetic
quantities, vector algebra.
UNIT II Biomechanics of Bone Growth and Skeletal Muscle 8
Bone growth and development, bone response to stress-osteoporosis,
Joint Architecture, joint stability, joint flexibility, techniques for
increasing joint flexibility, common joint injuries, Structural
organization of skeletal muscle, skeletal muscle function, factors
affecting muscular force generation, common muscle injuries.
UNIT III Biomechanics of the Human Upper Extremity 8
Structure of the shoulder, movements of the shoulder, loads on the
shoulder, common injuries of the shoulder, Joint-Articulating surface
motion of shoulder, Structure of the wrist, movements of the wrist,
structure of the joints of the hand, movements of the hand, common
injuries of the wrist and hand, Joint-Articulating surface motion of
Wrist,
UNIT IV Biomechanics of the Human Lower Extremity and Spine 8
Structure of the hip, movements at the hip, loads on the hip, common
injuries of the hip, Joint-Articulating surface motion of hip, Structure
of the knee and ankle, movements at the knee and ankle loads on the
knee and ankle, common injuries of the knee and ankle, Joint-
articulating surface motion of knee, Structure of the spine,
movements of the spine, muscles of the spine, loads on the spine,
common injuries of the back and neck.
Application of Biomechanics
Biomechanics in physical education, Biomechanics in strength and
conditioning, Gait analysis, biomechanics in sports medicine and
rehabilitation

Books Recommended:
1. Susan J Hall, “Basic Biomechanics”, McGraw-Hill Higher Education, 7th edition,
2014.
Reference materials:
1. Donald R. Peterson and Joseph D. Bronzino, “Biomechanics- Principles and
Applications”, CRC Press, 2nd edition, 2008.
2. Duane Knudson, “Fundamental of biomechanics”, Springer, 2nd edition, 2007
3. Fung Y C, Biomechanics: “Mechanical Properties of Living Tissues”, Springer, 2nd
edition, 1993
 BIOMEDICAL SIGNALS AND SYSTEMS

BE276
(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: To purpose of learning this course on biomedical signals and systems for biomedical engineering
students is to acquire knowledge for analyzing the continuous time discrete time signals & systems and its
biosignal applications.

UNIT I Basics of signals 8

Signal Classification; continuous time versus discrete time, periodic
versus not periodic, analog versus digital, deterministic versus
random,
Basic signals; Sinusoidal, exponential, unit impulse, unit step, unit
ramp
Mathematical operations on signals; scaling, folding, time shifting,
addition, multiplication, convolution, correlation
UNIT II Basics of systems 8
Classification of systems: static and dynamic systems, time
invariant and time variant, linear and nonlinear systems,
causal and non-causal systems, stable and unstable systems
Linear Time invariant systems (LTI) representation; impulse
response, transfer function, constant coefficient differential equation
UNIT III Analysis of Continuous Time Signals and System 10
Fourier series analysis; complex form
Fourier transform; properties
Relation between Laplace transform and Fourier transform
Fourier transform application to LTI systems
UNIT IV Analysis of discrete Time Signals and System 6
Sampling Theorem; ideal sampling and reconstruction
Z transform; properties, region of convergence (ROC)-
representation
of poles and zeros in z transform
Relation between Z transform and DTFT
Z transform application to LTI systems
UNIT V Application to Bio Signals 8
Introduction, Characteristics of Bio–Signals, Types of Signals,
Measurement, Transformation and reduction
Application areas of Bio -Signals analysis – EEG, ECG,
Phonocardiogram,

Books Recommended:
1. Allan V. Oppenheim, Alan S. Willsky and S. Hamid, “Signals and systems”, Prentice Hall of India
Pvt.Ltd, 2nd edition, 1997.
Reference materials:
1. M.J. Roberts, “Signals and Systems: Analysis using transform methods & MATLAB” Tata McGraw
Hill,2 edition, 2007.
nd

2. Suresh R, Devashayam, “Signals and Systems in Biomedical Engineering”, Springer US, 2 edition,
nd

2013.
 DIGITAL LOGIC CIRUITS FOR CLINICAL ENGINEERS
EC235

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: To impart knowledge of digital logic circuits for and its application in the bio-
medical field.

UNIT I Boolean Algebra and Logic gates 8

Review of Number system: Binary, Octal, Hexadecimal number
system, Complements
Logic gates, Boolean algebra postulates and theorems,
Boolean function minimization:, Karnaugh map, Quine McCluskey
method
UNIT II Combinational Circuit 8
Analysis and design of combinational circuit, Half adder and full
adder circuits, parallel adder /Subtractor, magnitude comparator
Encoder and decoder, Multiplexer and de-multiplexer,
UNIT III Sequential Circuit 8
Latches, Flip Flops; JK, D,T, Characteristics table and equation
Analysis and design of clocked sequential circuits
4 bit shift register
Counters: Modulo N counter, ring counter, ripple counter
UNIT IV Logic families and Memory 8
Logic family characteristics and their comparison,
Types of Memory: RAM, ROM, PLD’s
Medical Applications
Digital Blood pressure Monitor,
Digital Blood Glucose monitor,
Digital thermometer,
Heart rate Monitor
Digital stethoscope,
Hearing Aid

Books Recommended:
1. M.Morris Mano and Michael D.Ciletti, “Digital design”, Pearson, 5th edition
2013.William H. Hayt, Jack e. Kemmerly & Steven M. Durbin, Engineering Circuit
Analysis, McGraw Hill International, sixth edition, 2202.
2. Thomas L. Floyd, “Digital fundamentals”, Pearson, 11th edition 2015.
Reference materials:
3. https://www.nxp.com/applications/solutions/internet-of-things/smart-
things/healthcare:HEALTHCARE-MEDICAL
 MEDICAL OPTICS
PY-206
(w.e.f. session 2019 – 2020)

Pre-requisites Co-requisites L T P C

None None 2 1 0 3

Objective: To impart detailed knowledge about the principles and working of Laser and
Optical Fibers. To give brief knowledge about integration of Laser and Fiber optics
techniques for therapeutic, diagnosis and imaging modalities

No. of
Unit Syllabus
Lectures

Introduction and Brief history of optical fiber communication,

Principle of optical fiber communication, Basic Structure of
Fiber Optic Cable, Parameters of Fiber Optic Cable- Acceptance
UNIT I: Angle, Acceptance Cone and Numerical Aperture, Different
8
Optical Fiber Modes of Fiber Optic Cable- Single Mode, Multimode, Graded
index Fiber, Different types of Losses and Dispersions in Fiber
Optic Cable, Problems in connecting Optical fibers, Cleaving
process, connectors and couplers.

Medical Lasers: quality control, safety standards,

and regulations - Laser Bio effects and Concepts Of Nominal
UNIT II: Hazard Zone, Maximum Permissible
8
Medical Laser Exposure, Classification of Lasers, Common Lasers and Useful
Definitions, Basic Biological Effects,
Depth of Penetration.

UNIT III: Introduction, Fundamentals of Laser assisted diagnosis and

therapy, Applications of Lasers in diagnosis and imaging, Laser
Application of interaction with materials and tissues, Integrated Laser – Fiber
Lasers in 8
system and their applications, Complications in use of Laser
Therapy & Fiber Optics system
Diagnosis

Unit IV: Fundamentals of endoscopic imaging systems, Angioscope, 8

videoscopy, Fluorescence endoscopy, Endoscopic therapy,
Endoscopy & Principle of ultrasound Endoscopic ultrasound.
Applications of
Fiber Optic Fiber Optic Laser system in Cardiovascular disease,
Laser System Gastroenterology, Neurosurgery, Ophthalmology, Urology etc.
 Flow chart diagram for Clinical applications of Laser-Fiber
system

Recommended Books:

1. Abraham Katzir, ‘Lasers and Optical Fibers in Medicine’, 1st Edition, 1993, Academic
Press Inc.
2. John Crisp, ‘Introduction to Fiber Optics’, 2nd Edition, 2001, Newnes.

Tuan Vo-Dinh, ‘Biomedical Photonics Handbook’, 1st Edition, 2003, CRC Press.

INTEGRATED CIRCUIT FOR BIOINSTRUMENTATION

EC-236
(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 3 1 0 4

Objective: To enable the students to understand the fundamentals of linear integrated circuits
and its implement in relation to the various medical related applications
UNIT I Opamp and Its Characteristics 8
Basics of operational amplifier (op amp) and its ideal Characteristics
Op amp-inverting amplifier, non-inverting amplifier, buffer
amplifier, AC amplifier
Differential amplifier, Instrumentation Amplifier
UNIT II Op-Amp applications 8
Inverting and non-inverting adder, Subtractor, V-I and I-V converter,
Half wave rectifier and full wave rectifier, Differentiator, Integrator,
log amplifier
UNIT III Comparators and Waveform Generators 8
Comparator and its applications
Schmitt trigger, Monostable multivibrator,, Astable multivibrator,
Triangular wave generator, Sawtooth wave generator
UNIT IV Filters and data converter 8
First order RC active low pass and high pass filter, Band pass filter
Digital to analog converter (DAC)/ Analog to digital converter
(ADC) specifications
Weighted resistor DAC, R-2R ladder DAC, inverted R-2R DAC,
Flash type ADC, successive approximation ADC and dual slope
ADC
UNIT V Timer, and Voltage Regulators 8
 555 timer IC pin diagram and functional diagram,
555 timer in monostable mode and a stable mode
Voltage controlled oscillator (VCO), Phase Locked loop (PLL)
Voltage regulator; Series op-amp regulator, fixed voltage regulator
Medical Applications: pulse oximetry, bio data acquisition system

Books Recommended:
1. D Roy Choudhury and Shail Jain, “Linear integrated circuits”, New Age Science
Limited, 4th edition, 2011.
Reference materials:
1. Gayakwad A.R, “Op-Amp and linear integrated circuits”, Prentice Hall of India, 4th
edition, 2009.

3.
 BIOMATERIALS AND ARTIFICIAL ORGANS

BE277

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: The purpose of learning this course is to provide an understanding of different

biomaterials and their applications in implantable medical devices and organs.
UNIT I Essential Biomaterial Science 8
Introduction: Metallic biomaterials, Ceramic biomaterials, Polymeric
biomaterials, Composite biomaterials, Physical, mechanical and
surface properties, Characteristics testing-biocompatibility, Cells and
tissues, inflammation and wound healing
UNIT II Commodity Biomaterials: 8
Titanium and cobalt-chromium alloys for hips and knees, Polymeric
joint bearing surfaces for total joint replacements, Biomaterials for
pacemakers, defibrillators, Mechanical and bio prosthetic heart
valve, Recent advancement in commodity biomaterials
UNIT III Advanced Biomaterials 8
New ceramics for joint replacement surgery, Composites for joint
replacement surgery, New biomaterials for improving the blood and
tissue compatibility of total artificial hearts (TAH), Ventricular assist
devices (VAD), Recent advancement in next generation biomaterials
UNIT IV Implantable Medical Devices and Organs 8
Implants in liver, Implants in kidney, Implants in eyes, Implants in
ears, Recent advancement and future directions . Gastrointestinal
system, Dentistry, Maxillofacial and craniofacial replacement, Soft
tissue repair, replacement and augmentation, Recent advancement
and future directions.

Books Recommended:
1. David Williams, “Essential biomaterials science”, Cambridge University Press, 1st
edition, 2014.
2. Lysaght M, Webster T J., “Biomaterials for artificial organs”, Woodhead Publishing
Limited, 1st edition, 2011.
Reference materials:
1. Jason A. Burdick, Robert L. Mauck., “Biomaterials for tissue engineering
applications”, Springer, 1st edition, 2014.
2. Joseph D. Bronzino, Donald R. Peterson., “Biomedical engineering fundamentals”,
CRC Press, 4th edition, 2014.
3. Hench L, Jones J., “Biomaterials, artificial organs and tissue engineering”, Woodhead
Publishing Limited, 1st edition, 2005.
 PRINCIPLES OF MANAGEMENT, INDUSTRIAL ECONOMICS & IPR

BM229

(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 2 1 0 3

Objective: The basic objective of this course is to provide fundamental knowledge about
Principles of Management, Industrial Economics & Intellectual Property Rights. This will
help the students in analyzing the current economic scenario as well as give the required
skills to develop and protect the ideas & skills they possess.

UNIT I Industrial Economics: Concept, Nature and significance; Demand 8

and supply: Concept, Law; Elasticity of demand and supply; Theory
of consumer behavior, Indifference curve analysis.
UNIT II Money: Concepts, inflation and Deflation; Banking system in India: 8
Commercial and Central banking-Structure and types.
UNIT III Management: introduction, functions; Evaluation of Management 8
thoughts; Human Behavior in organization: Perception, Personality
development and interpersonal relationship.
UNIT IV Jurisprudential definitions and concepts of property, rights, duties 8
and their correlation; History and evolution of IPR (patent, design,
copyright and Geographical indication). Significance of IPR;
Requirement of a patentable novelty: Obtaining patent; Invention
step and prior art and state of art procedure; Issues related to IPR
protection of software and database; IPR protection of life forms:
biological products, International convention in IPR; Infringement or
violation, remedies against infringement: civil and criminal. Indian
Patent Act 1970 (amendment 2000); Major changes in Indian patent
system as post TRIPS effects.

Book References:
1. Old and Primrose “Principles of Gene Manipulation”.
2. Keru M “Ethical Biotechnology”, Global Vision Publishing House.
3. IHUxley TH “Evolution and ethics”, Princeton University Press.
 ELECTROTHERAPY LAB
BE278
(w.e.f. session 2019-2020)

Pre-requisite Co-requisite L T P C

None None 0 0 2 1

Objective: This course involves a demonstration of some basic physical principles as they
relate to the application of electrotherapeutic modalities. The student should be able to
explain the physical rationale for the use of physical agent modalities.

List of Experiments

1. Diode and Triode valves, Transistors, Ammeter, Voltmeter, Galvanometer, Rheostat,

Resistance Box, Transformer, etc.
2. Demonstration of Electrotherapy units like Stimulator, Short Wave Diathermy, Micro
Wave Diathermy, LASER and Ultrasound, etc.
3. Clinical observation of equipment placement.