Scabicides and

Anti- Pedicular Agents

Pharmaceutical and Medicinal
Organic Chemistry
• Scabicides- compounds used to control the mite
Sarcoptes scabei, an organism that thrives under
conditions of poor personal hygiene
SCABICIDES
Permethrin
• Exerts a lethal action
against lice, ticks, mites
and fleas
• 1st line drug

Benzyl benzoate

• Obtained from peru

balsam and other resins
• Immediate relief from
itching
PEDICULICIDAL
• Pediculicides- compounds used to eliminate
head, body, and crab lice
Pyrethrin
• Derived from
chrysanthemum plants
• MOA: Nerve poisoning

Piperonyl butoxide

• Enhances the
pediculicide effects of
pyrethrins
Permethrin
• For head lice only

Lindane (Kwell®, Scabene®, Kwildane®)

• Benzene hexachloride
• ADR: Neurotoxicity