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6777 Nancy Ridge Drive

San Diego, CA 92121
Tel: (858)458-0866
Fax: (858)458-0833
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Alpha factor mating pheromone Yeast peptide

Catalog Number: 06-271-83056

Related Product Names:

- MFA1 peptide; MFA1; Alpha factor mating pheromone Yeast
- Mating hormone A-factor 1

- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product
details. For more information please contact sales@genwaybio.com.

Gene Name: MFA1 Gene Name Synonym: N/A

Gi #: 462595 NCBI Acc #: P34165 Swiss Prot Acc #: P34165

Length (aa): 36 Mol. Weight (Da): 1684.2 Chrom Location: N/A

Sequence (One Letter Code): WHWLQLKPGQPMY

Sequence: {TRP} {HIS} {TRP} {LEU} {GLN} {LEU} {LYS} {PRO} {GLY} {GLN} {PRO} {MET} {TYR}

MW: 1683.98

CAS: 59401-28-4

Formula: C82H114N20O17S

Solubility: Soluble in water.

Notes: Simply thaw and use directly. We recommend using it at concentrations ranging from 5 uM (bar1 D) to
100 uM (BAR1).

Purity/Purification: > 95%

Storage: Store this peptide in its dry form at 4C. For best results, rehydrate the peptide immediately before
use. Do not re-freeze any unused portions.

Shipping: Products may be shipped on ice pack or dry ice.

TESTING: (secondary reagents and protocols)

Not Available

MFA1 PEPTIDE TARGET DESCRIPTION:

Synonym Names for MFA1 peptide: MFA1; Mating hormone A-factor 1

The alpha factor pheromone arrests yeast in G1 of the cell cycle. Alpha factor mating pheromone induces the
expression of mating genes. Alpha factor mating pheromone changes in nuclear architecture. and Alpha factor
mating pheromone polarized growth toward the mating partner. STE2 encodes the alpha factor pheromone
receptor (a GPCR) found on mating-type a cells in the yeast.

Function: The active factor is excreted into the culture medium by haploid cells of the A mating type and acts on
cells of the opposite mating type (type alpha). It mediates the conjugation process between the two types by
inhibiting the initiation of DNA synthesis in type alpha cells and synchronizing them with type A.
Subcellular Location: Cell membrane; lipid-anchor; cytoplasmic side (Potential).

Miscellaneous: Present with 28900 molecules/cell.

BACKGROUND REFERENCES for MFA1 PEPTIDE:

Background references for antibody target are not specific to GenWay products
[1] Brake,A.J., Brenner,C., Najarian,R., Laybourn,P. and Merryweather,J.
Structure of genes encoding precursors of the yeast peptide mating pheromone a-factor
[2] Michaelis,S. and Herskowitz,I., et al.
The a-factor pheromone of Saccharomyces cerevisiae is essential for mating
[3] Jacq,C., Alt-Moerbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.G., Bargues,M., Baron,L., Becker,A.,
Biteau,N.,, et al.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
[4] Marsischky,G., Rolfs,A., Richardson,A., Kane,M., Baqui,M., Taycher,E., Hu,Y., Vannberg,F., Weger,J.,
Kramer,J., Moreira,D.,, et al.
Direct Submission
[5] Betz,R., Crabb,J.W., Meyer,H.E., Wittig,R. and Duntze,W., et al.
Amino acid sequences of a-factor mating peptides from Saccharomyces cerevisiae
[6] Brake A.J., Brenner C., Najarian R., Laybourn P., Merryweather J.
Structure of genes encoding precursors of the yeast peptide mating pheromone a-factor.
[7] Michaelis S., Herskowitz I.
The a-factor pheromone of Saccharomyces cerevisiae is essential for mating.
[8] Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau
N., et al.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
[9] Marsischky G., Rolfs A., Richardson A., Kane M., Baqui M., Taycher E., Hu Y., Vannberg F., Weger J., Kramer
J., et al.
Creation of the YFLEX clone resource: cloning of Saccharomyces cerevisiae ORFs in the Gateway
recombinational cloning system.
[10] Betz R., Crabb J.W., Meyer H.E., Wittig R., Duntze W.
Amino acid sequences of a-factor mating peptides from Saccharomyces cerevisiae.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact
GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: MFA1 peptide is for in vitro research use only. Not for use in diagnostics or therapeutic
procedures.

Important Notes: During shipment, small volumes of MFA1 peptide vial. For products with volumes of 200 µL
or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop
centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed
on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-
Prot/TrEMBL and NCBI. To better serve our clients with everything we know about MFA1 peptide, all related
information, articles, resources about MFA1 peptide are being stored on our online database. Let us know if you
have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any
legal liability or responsibility for the accuracy, completeness or utility of any information, product or process
disclosed.

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Tel: (858)458-0866 Fax: (858)458-0833 Email: sales@genwaybio.com
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