Important Topics

PHARMACOLOGY AND THERAPEUTICS

Antihypertensive drugs, Pharmodynamics( Indication & side
effects of Thiazide Diaretics).
Drug Administration (Merit & Demerit)
Classify pharasympatholytics,
Pharmacodynamics: Indication & side effects of atropine; Beta
blocker, contraindication
Drug used in peptic ulcer
Side effects of proton pump inhibitor.
Propranolol
Classification of Bronchodliator.
Classification of oral antidiabetic drugs.
Pharmacological action, clinical use & side effects
Renin angiotensin aldosterone blocker; classification
Drug metabolism ; role of cytochrome P-450, Factor
influencing drug metabolism
Drug receptor
Metocloparmide as anti-emetic
Furosemide as diuretics
Neostigmine
Diuretics classification
Define pharmacological, indications and side effects of loop
diuetrics, side effect of atropine
Classification of pharsympatholutic drugs
Bio transformation; discuss its different phases
Classify antihyperlipdameic ;Action, Clinical use and side
effects of HGM-CoA reductase inhibitor
Sodium Nitroprusside
Route of drug administration
Classification of oral antibiotics drugs
Sympathomimetic drugs
Biosynthesis; pharmacological actions; clinical use and side
effects of Adrenaline
Antihypertensive drugs;
Drugs used in peptic ulcer
Drug Metabolism and its different phases
Discuss mechainism, action, therputic use and side effect of
proton pumpinhibitor
Volume of distribution
Classification of Antihistamine
Types of drug receptors
Drug dependence
Atropine; side effects, contra-indications
Mechanism of action and Adverse effects Sodium Nitroprusside
and Frusemide
Mechanism of action and Adverse effects Methyl dopa, Digoxin
Mechanism of action and Adverse effects of succinyl choline
Pharmacological properties and therapeutics use and side
effect; organophosphorus compounds and Alpha- Blocker
Tachyphylaxis ; N. fedipine, d-tubocraeine, Methhyl dopa,
Spironolactone, Hydralazine, Neostigmine, Succinylcholine
Bio- Transformation of drugs
Metaclopramide
Classify pharasympatholytics drugs
Classify Antocholinergic Drugand discuss Antropine
Classify Anti-Anginal Drugs; therapeutics use and side effect
Nitroglycerine
Plasma Half life of a drug
Therapeutics Index
Discuss graded and quantal dose response relationship
Bioavailability
Classify sypathominntics; describe biosythessis, metabolism,
uses of Adernaline. Differentiate its action from Ephedrine.
Cough and Asthma,. Classify Bronchodliators. Discuss briefly
di-sodioum chro,oglycare, Theophylline, and ipratropium
Classify Neo-Muscular blocking drugs,
Discuss glucuronide conjugation
Define and classify autacoids, discuss action of hiostamine
Pharmacological properties and therapeutics use and side
effect; Antihastamine
Adrenaline in anaphylactic shock; Explain
Antropine in organophosphate poisioning
Use of misprostol for pepticulacer induced by NSAIDs.
Scopolamine in motion sickness
Classify Beta-Blocker. Pharmacological properties and
therapeutics use and side effect; propranolol
Pharmacological properties of Antropine, & Homatropine :
Neostigmine & Physosstigmine : Adrenaline & Noradrenaline
Phase-ii metabolism in detail

PHARMACEUTICS-II
Classify Tablets according to the metjhod of manufacture &
types of drug delivery system
Wet granulation
Propellants, Liquified gas propellant, various types
Two-Phase system, also aerosol
Rotary die process for filling capsule
Syrup and elixris
Disintengants and Binder
Wet Gum method for emulsion
Suspending agent
Collodion
Example on Mole?
Classification of suppositories and its preparation and storage
Ointment bases and preparation of oinment
Advantage of Parental preparation, component of parental
Merit and Demerit of tablet dosage form
Dry Granulation and method of tablet manufacture
Classes and designation of tablets
USP syrup; self preserved
Elixirs from syrup; differentiate
Spirit and Aromatic Water and Tinetures
Cold filling process of aerosol
Cream
Preparation of tablets by direct compression method
Binder and Adhesive, lubricants, disintegrants
Classify tablets excipients and tablets with example.
Importance of tablet granulation
Soft gelatin capsule
Rotary die process along with simple diagram
Topical powder
Various formulas used in calculating doses for children
Method of syrup preparation
Define and Classify aerosol , various prpllent use in
manufacturing aerosol
Enlist tablet granulation
Advantage and disadvantage of suppositories; how they are
packed and stored
Solvent and vehicle of injection
Uses and packing powder in detail
Transdermal drug delivery system
Gel and Magma
HLB values with reference to emulsion formulation
Fusion method for preparation of suppositories, oinments
Isotonic solution
Pastes
Explain hard gelatin capsule and filling of hard gelatin capsule
Official use of injections

PHARMACEUTICAL MICROBIOLOGY
Bacterial growth curve
Factor affecting growth of bacteria
Virus structure and function and its Classification
Human immunodeficiency virus
Influenza virus
Rabies virus
Structure of monomeric antibody, classify and function of
antibodies
Penicillin production and purification
Factory and hospital hygene
Bacterial cell structure and Function
Bacterial staining methods
Immunity; types with example
Fermentation; production of erythromycin
Sterilization and disinfection; differentiate;both study in detail
Malaria; transmission, Pathogenesis, clinical findings,
treatment control and prevention
Fungal infection
Culture media
Hepatitis
Measles
Hypersensitivity and its types; All hypersensitivity reaction
with example
Cephalosporin and Pencilin production by fermentation
Mycotic infection
Classification of parasites,
Life cycle and pathogenicity of Malarial parasite
Enlist 4gm +ve and 4gm –ve bacteria; discuss capsule cell wall
and spore of the bacterial cell.
Fermentation; Fermentative production of Penicillin
Manufacturing of sterile pharmaceutical products
Differentiate b/w vaccine and seras ; types of vaccine in detail
Sterile manufacturing

PHARMACOGNOSY
Enzyme
Factor affecting enzyme activity
Pepsin and papain
Botanical sources, family , part, chemical constitiuent and
medicinal of following:-
Larkspur, Opium, Rauwolfia, Atropa, Digital. Aloe, Glycyrrhiza,
Fennel, Colchicum
Classify allergens, inhalant allergens
Allergy; Diagnosing allergy
Importance of crude drug drying
Cod liver oil
Crude drug evaluation and its production for commercial
market
Natural pesticides
Surgical cotton
Diagram of clove
Adulteration of crude drug
Croton tiglium as poisonous drug
Opium
Asafoetida
Glycyrhiza
Belladona
Auxins
Curing
Natural pesticides; Name it; Explain pyrethrum flower?
Path enzymes? Mechanism and treatment of poisoning by
bitter almond
Standard for pepsin,popain, & pacrelipase
PAKISTAN STUDY
Ideology of Pakistan seen and enunciated by Allama Iqbal
Factor leading to the Muslim separation in British India
Strategic importance of Pakistan Location?
Ethnicity, Impact on poloitical and government of Pak
Two Nation theory justification of sub-continent
Khilafat Movement
Pakistan resolution
Efforts made for islamization by diff govt
Purpose for creation of Pakistan
S.S Ahmed Khan Aligharh movement
Fourteen points of Jinnah
Congress attitude at Nehru report
Feature of 1973 Constitution
Natural resources of Pakistan
Problem faced by Muslim world
Geographical importance of Pakistan
Weak democracy; suggestion for sustainable democracy
Environmental issues of Pakistan
Kashmir issue Problems and Prospects
Natural resources of Pakistan
Suggestion for political and economical Development of
Pakistan
Fundamental factor for the Establishment of Pakistan
Socio-Ecnomic reformsduring Zulfiqar Ali Bhutoo (1972-1977)