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  • Streptokinase Vs RT PA Updated 2020

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    AHMED TANJIMUL ISLAM
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    This document compares properties of different thrombolytic drugs used to treat blood clots. It shows that rt-PA has high fibrin specificity and a short half-life, resulting in high patency rates of 75-85%. While streptokinase does not have fibrin specificity, it has a longer half-life of 20 hours but lower patency rates of 60-65%. Tenecteplase has the highest fibrin specificity and an even longer half-life of 20 hours, also resulting in high patency rates of 85%.

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    This document compares properties of different thrombolytic drugs used to treat blood clots. It shows that rt-PA has high fibrin specificity and a short half-life, resulting in high patency rates of 75-85%. While streptokinase does not have fibrin specificity, it has a longer half-life of 20 hours but lower patency rates of 60-65%. Tenecteplase has the highest fibrin specificity and an even longer half-life of 20 hours, also resulting in high patency rates of 85%.

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    17 views1 page

    Streptokinase Vs RT PA Updated 2020

    Uploaded by

    AHMED TANJIMUL ISLAM
    This document compares properties of different thrombolytic drugs used to treat blood clots. It shows that rt-PA has high fibrin specificity and a short half-life, resulting in high patency rates of 75-85%. While streptokinase does not have fibrin specificity, it has a longer half-life of 20 hours but lower patency rates of 60-65%. Tenecteplase has the highest fibrin specificity and an even longer half-life of 20 hours, also resulting in high patency rates of 85%.

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    of 1

    Streptokinase Vs rt-PA

    Fibrin specificity Half life Patency rate


    Rt PA ++ 5 hrs 75-85%
    Reteplase ++ 15 hrs 85%
    Tenecteplase ++++ 20 hrs 85%
    Streptokinase No 20 hrs 60-65%

    Dr. Ahmed Tanjimul Islam


    MBBS, MSc (Leeds, England),
    PGD (UNSW, Australia) MD (Neurology)
    Medical Officer of Neurology,
    Rajshahi Medical College Hospital, Bangladesh

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