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ANTIALLERGICS
I.A. ANTIHISTAMINES
DOSAGE FORM AND
GENERIC NAME BRAND NAME MODE OF ACTION INDICATIONS
STRENGTH
Desloratadine Clarinex Tablets 5mg Long-acting histamine antagonist Relief of nasal and non-nasal symptoms of
with selective H1-receptor seasonal and perennial allergic rhinitis; in
histamine antagonist activity chronic idiopathic urticaria for relief of
symptoms of pruritus and reduction in
number and size of hives.
Cetirizine Zyrtec Tablets 5mg/10mg Competitively antagonizes Symptomatic relief of symptoms (nasal and
histamine at the H1 receptor site nonnasal) associated with seasonal and
perennial allergic rhinitis; treatment of
uncomplicated skin manifestations of
chronic idiopathic urticaria.
Diphenhydramine HCl Benadryl Injection50 mg/mL Competitively antagonizes Symptomatic relief of perennial and
histamine at H1 receptor sites. seasonal allergic rhinitis, vasomotor rhinitis
and allergic conjunctivitis; temporary relief
of runny nose and sneezing caused by
common cold;
Benadryl Allergy Capsules, soft-gels 25 mg; relief of allergic and nonallergic pruritic
Tablets 25 mg;Tablets symptoms; treatment of urticaria and
chewable 12.5 mg; Liquid angioedema; amelioration of allergic
12.5 mg/5 mL reactions to blood or plasma; adjunct to
epinephrine and other standard measures in
anaphylaxis;
Banophen Capsules 25 mg
DOSAGE FORM AND
GENERIC NAME BRAND NAME MODE OF ACTION INDICATIONS
STRENGTH
Loratadine Claritin Tablets: 10 mg, Tablets, Competitively antagonizes Symptomatic relief (nasal and nonnasal) of
rapidly disintegrating: 10 histamine at the H1-receptor site. symptoms associated with seasonal allergic
mg, Syrup: 1 mg/mL rhinitis; treatment of chronic idiopathic
urticaria.
Hydroxyzine HCl Atarax Tablets 10 mg, 25 mg, 50 May be caused by suppression of Symptomatic relief of anxiety and tension
mg, 100 mg; Syrup 10 mg/5 activity in subcortical areas of associated with psychoneurosis; adjunct
mL CNS. therapy in organic disease states with
anxiety; management of pruritus caused by
allergic conditions; sedative before and after
general anesthesia (PO only).
Amlodipine Norvasc Tablets 2.5 mg, 5mg, Inhibits movement of calcium ions Hypertension; chronic stable angina;
10 mg across cell membrane in systemic vasospastic (Prinzmetal's or variant)
and coronary vascular smooth angina.
muscle.
ROUTE OF ADMINISTRATION
Atenolol Tenormin, APO- Blocks beta receptors, primarily Treatment of hypertension (used alone or in
Atenol, Gen-Atenolol, affecting heart (slows rate), vascular combination with other drugs), angina
Med-Atenolol, Novo- system (decreases BP) and, to lesser pectoris resulting from coronary
Atenol, Nu-Atenol, extent, lungs (reduces function). atherosclerosis, acute MI. Unlabeled
Schein Pharm use(s): Migraine prophylaxis, alcohol
Atenolol, Taro Atenolol, withdrawal syndrome, ventricular
Tenolin, Tenormin arrhythmias, supraventricular arrhythmias or
tachycardias, esophageal varices
rebleeding, anxiety.
Betaxolol HCl Betoptic, Betoptic S Blocks beta receptors, primarily Hypertension. Ophthalmic preparation:
affecting cardiovascular system Lowering IOP; ocular hypertension; chronic
(decreases heart rate, cardiac open-angle glaucoma.
contractility and BP) and lungs
(promotes bronchospasm).
Ophthalmic use reduces intraocular
pressure, probably by reducing
aqueous production.
II. CARDIOVASCULAR DRUGS
II.B. BETA-ADRENERGIC BLOCKER
Nadolol Corgard, Alti-Nadolol, Blocks beta-receptors, which primarily Management of hypertension and angina
Apo-Nadol, Novo- affect cardiovascular system pectoris
Nadolol (decreases heart rate, contractility and
BP) and lungs (promotes
bronchospasm).
Isosorbide Mononitrate ISMO, Imdur, Monoket, Relaxation of smooth muscle of Prevention of angina pectoris.
Isotrate ER venous and arterial vasculature.
Isosorbide Dinitrate Dilatrate-SR, Isordil, Isordil Relaxation of smooth muscle of Treatment and prevention of angina
Tembids, Isodril Titradose, venous and arterial vasculature. pectoris.
Sorbitrate, APO-ISDN,
Cedocard-SR
II. CARDIOVASCULAR DRUGS
II.C. ANTI-ANGINAL DRUGS
Dopamine HCl Intropin, Revimine Stimulates beta1 receptors in Correction of hemodynamic imbalances
heart, causing more complete present in shock after MI; trauma,
and forceful contractions endotoxic septicemia, surgery and renal
(inotropy). Also acts on alpha failure or imbalances in conditions of
receptors (dose dependent) and chronic refractory cardiac decompensation
has dopaminergic effects. (eg, CHF).
Epinephrine Adrenalin Chloride Solution: Stimulates both alpha-and beta- Treatment and prophylaxis of cardiac
0.1%, 1 mg/mL as HCl; Ana- receptors (alpha-receptors at arrest and attacks of transitory
Kit Asthma Nefrin Solution for high doses; beta1 - and beta2 atrioventricular heart block; treatment of
inhalation: 2.25%; Nephron: -receptors at moderate doses) Adams-Stokes syndrome; treatment of hay
Solution for inhalation: 2.25% within sympathetic nervous fever; relief of bronchial asthma; treatment
racepinephrine HCl (1.125% system. Relaxes smooth muscle of syncope caused by heart block or
epinephrine of bronchi and iris and is carotid sinus hypersensitivity; symptomatic
base)racepinephrine HCl antagonist of histamine. relief of serum sickness, urticaria and
(1.125% epinephrine base); angioedema; relaxation of uterine
Epifri: Solution: 0.5%, 1%, musculature; anaphylaxis;
2%
II. CARDIOVASCULAR DRUGS
II.D. VASOPRESSOR
Diphenhydramine HCl AllerMax Tablets 50 mg Competitively antagonizes Symptomatic relief of perennial and
histamine at H1 receptor sites. seasonal allergic rhinitis, vasomotor rhinitis
and allergic conjunctivitis; temporary relief
of runny nose and sneezing caused by
common cold; relief of allergic and
DOSAGE FORM AND
GENERIC NAME BRAND NAME MODE OF ACTION INDICATIONS
STRENGTH Competitively antagonizes Symptomatic relief of perennial and
AllerMax Allergy and Liquid 6.25 mg/5 mL histamine at H1 receptor sites. seasonal allergic rhinitis, vasomotor rhinitis
Cough Formula and allergic conjunctivitis; temporary relief
of runny nose and sneezing caused by
Banophen Capsules 25 mg common cold; relief of allergic and
Benadryl Injection 50 mg/mL nonallergic pruritic symptoms; treatment of
Benadryl Allergy Capsules, soft-gels 25 mg urticaria and angioedema; amelioration of
Tablets 25 mg; Tablets, allergic reactions to blood or plasma;
chewable 12.5 mg Liquid
12.5 mg/5 mL
III.C. CORTICOSTEROIDS
Hydrocortisone (Cortisol) Hydrocortisone Buteprate Short-acting glucocorticoid that Treatment of primary or secondary adrenal
Pandel; Hydrocortisone depresses formation, release, and cortex insufficiency, rheumatic disorders,
Butyrate Locoid; activity of endogenous mediators collagen diseases, dermatologic diseases,
Hydrocortisone of inflammation including allergic states, allergic and inflammatory
Cypionate Cortef; prostaglandins, kinins, histamine, ophthalmic processes, respiratory diseases,
Hydrocortisone liposomal enzymes, and hematologic disorders (idiopathic
Phosphate Hydrocortisone complement system. Also modifies thrombocytopenic purpura), neoplastic
Phosphate;Hydrocortison body's immune response. diseases, edematous states (resulting from
e Sodium Succinate A- nephrotic syndrome), GI diseases
Hydrocort, Solu-Cortef (ulcerative colitis and sprue), multiple
sclerosis, tuberculous meningitis, trichinosis
with neurologic or myocardial involvement.
DOSAGE FORM AND
GENERIC NAME BRAND NAME MODE OF ACTION INDICATIONS
STRENGTH
Beclomethasone Beclovent Aerosol: 42 mcg/actuation Has potent anti-inflammatory effect Oral inhalation: QVAR: Maintenance
Dipropionate on respiratory tract and in nasal prophylactic treatment of asthma; asthma
passages. patients requiring systemic corticosteroid
Beconase Aerosol: 42 mcg/actuation
administration where adding an inhaled
corticosteroid may reduce or eliminate need
for systemic corticosteroids.
Beconase AQ Spray: 0.042%
beclomethasone
dipropionate, monohydrate
Budesonide Pulmicort Turbuhaler Powder: 200 mcg (each Exerts potent anti-inflammatory Intranasal: Management of seasonal and
actuation delivers effect on nasal passages. perennial allergic rhinitis symptoms in adults
approximately 160 and children (Rhinocort, Rhinocort Aqua);
mcg)/metered dose management of nonallergic perennial rhinitis
in adults (Rhinocort only). Oral inhalation:
For the maintenance treatment of asthma
Pulmicort Respules Inhalation suspension: 0.25 as prophylactic therapy in adults and
mg/2 mL children and for patients requiring oral
Inhalation suspension: 0.5 corticosteroid therapy for asthma (inhaler).
mg/2 mL
Rhinocort Aerosol: approximately 32
mcg micronized
budesonide/actuation. With
propellants.
ROUTE OF ADMINISTRATION
ADULTS: PO 25 mg
phenylpropanolamine/100 to 400 mg
guaifenesin q 4 hr (immediate release
tablets) or 75 mg
phenylpropanolamine/100 to 600 mg
guaifenesin q 12 hr (sustained release
tablets). CHILDREN: PO 6.25 to 12.5
mg phenylpropanolamine/50 to 200 mg
guaifenesin q 4 hr.
HYDROCORTISONE BUTEPRATE
ADULTS & CHILDREN: Topical Apply
thin film to affected area bid.
HYDROCORTISONE BUTYRATE
ADULTS & CHILDREN: Topical Apply
sparingly to affected areas bid to qid.
HYDROCORTISONE AND
HYDROCORTISONE CYPIONATE
ADULTS & CHILDREN: PO 20 to 240
mg/day. HYDROCORTISONE
SODIUM PHOSPHATE ADULTS &
CHILDREN: IV/IM/SC 15 to 240
mg/day.
ROUTE OF ADMINISTRATION