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Dr Siraj Ahmad
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FMGE Revision: Newer Drugs

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Q. Vortioxetine is a recently approved agent for:


a. Epilepsy
b. On-Off phenomenon
c. Depression
d. Schizophrenia

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Q. A 65 year old male was on levodopa therapy


from last year. Now he develops the bradykinesia
hours after the drug intake. Which of the following
is the newly approved agent effective for this
condition:
a. Oprelevekin
b. Opicapone
c. Obidoxime
d. Omecamtive mecarbil

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Q. Remdesvir is recently been started in


management of Covid-19. This agent act by
inhibiting:
a. DNA dependent RNA polymerase
b. DNA dependent DNA polymerase
c. RNA dependent DNA polymerase
d. RNA dependent RNA polymerase

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Q. Mechanism of action of safinamide:


a. CRMP inhibitor
b. mGLUR5 receptor inhibitor
c. MAO-b inhibitor
d. COMT inhibitor

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True about Nicorandil


a.It is a nitrate ester that can cause vasodilation
b.It is a potassium channel blocker
c.It activate Na+/Ca+ exchanger
d.A and C both

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Q. Ranolazine is an approved drug for angina. It


acts by:
a. Fatty acid synthesis inhibitor
b. Na+K+ ATPase inhibitor
c. Late Na+ current entry inhibitor
d. Funny current blocker

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Q. The approved agent Nitarsudil is used in:


a. Angina
b. Arrhythmia
c. Glaucoma
d. Cataract

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Q. Edaravone is a recently approved agent for:


a. Multiple sclerosis
b. Wilsons’s disease
c. Amyotropic lateral sclerosis
d. Parkinsons disease

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Q. Which of the following is a 5HT4 receptor


agonist utilised in constipation dominant IBS:
a. Istradefylline
b. Prucalopride
c. Flibanserin
d. Lorcarserin

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• Istradefylline: Adenosine (A2A) receptor


antagonist

• Flibanserin: 5HT1a agonist. For hypoactive


sexual disorder in females.

• Lorcarserin: 5HT2c agonist. Obesity

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Q. Pretomanid is a newly approved agent for drug


resistant tuberculosis was launched in market.
This agent acts by:
A. Mycolic acid synthesis of MTB
B. ATP synthase inhibition of MTB
C. RNA polymerase inhibition
D. Myocolic acid inhibition of MTB

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Q. Omadacycline is a recently approved agent for:


a. Respiratory infection
b. Acne
c. Abdominal infection
d. burns

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Q. Which of the following antiepileptic drug


acts by CRMP protein inhibition:
a. Rufinamide
b. Safinamide
c. Lacosamide
d. Chlorpropamide

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