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  • Glyceryl Trinitrate IV, IV Nitroglycerin (Nitroglycerin IV) Dosing, Indications, Interactions, Adverse Effects, and More

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    Nafiul Islam
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    This document provides information on nitroglycerin intravenous (IV) for healthcare professionals, including dosing and uses. It is intended for treatment of angina with dosages starting at 5 mcg/min and increasing up to 20 mcg/min. Higher dosages may be needed depending on the type of IV administration set used. Uninterrupted infusion for over 24 hours can cause tolerance to develop. Renal dosing adjustments are also provided. Off-label uses include treatment of hypertensive crisis and variceal bleeds. Dosing for congestive heart failure is also outlined.

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    glyceryl trinitrate IV, IV Nitroglycerin (nitroglycerin IV) dosing, indications, interactions, adverse effects, and more

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    This document provides information on nitroglycerin intravenous (IV) for healthcare professionals, including dosing and uses. It is intended for treatment of angina with dosages starting at 5 mcg/min and increasing up to 20 mcg/min. Higher dosages may be needed depending on the type of IV administration set used. Uninterrupted infusion for over 24 hours can cause tolerance to develop. Renal dosing adjustments are also provided. Off-label uses include treatment of hypertensive crisis and variceal bleeds. Dosing for congestive heart failure is also outlined.

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    © All Rights Reserved
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    383 views2 pages

    Glyceryl Trinitrate IV, IV Nitroglycerin (Nitroglycerin IV) Dosing, Indications, Interactions, Adverse Effects, and More

    Uploaded by

    Nafiul Islam
    This document provides information on nitroglycerin intravenous (IV) for healthcare professionals, including dosing and uses. It is intended for treatment of angina with dosages starting at 5 mcg/min and increasing up to 20 mcg/min. Higher dosages may be needed depending on the type of IV administration set used. Uninterrupted infusion for over 24 hours can cause tolerance to develop. Renal dosing adjustments are also provided. Off-label uses include treatment of hypertensive crisis and variceal bleeds. Dosing for congestive heart failure is also outlined.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    nitroglycerin IV (Rx)
    Brand and Other Names: glyceryl trinitrate IV, IV Nitroglycerin, NitroBid IV, NTG, Tridil
    Classes: Nitrates, Angina

    Dosing & Uses


    Adult Pediatric

    Dosage Forms & Strengths

    infusion solution

    25mg/250mL
    50mg/250mL
    100mg/250mL

    injectable solution

    5mg/mL

    Angina

    If intolerant of or unresponsive to SL NTG

    5 mcg/min

    Increase by 5 mcg/min q3-5min up to 20 mcg/min, THEN  

    Increase by 10 mcg/min

    May later increase by 20 mcg/min

    Higher dosages required for PVC admin sets

    Uninterrupted infusion >24 hours produces tolerance

    Renal Failure

    CrCl: 10-50 mL/min: Administer q24-72hr

    CrCl: <10 mL/min: Administer q72-96hr

    Other Indications & Uses


    Angina pectoris, perioperative HTN, CHF in the setting of MI, induction of intra-operative hypotension

    Off-label: hypertensive crisis, variceal bleeds (with vasopressin), sympathomimetic-induced


    cardiopulmonary toxicities

    Dosage Forms & Strengths

    infusion solution

    25mg/250mL
    50mg/250mL
    100mg/250mL

    injectable solution

    5mg/mL

    Congestive Heart Failure

    Not FDA approved

    Initial: 0.25-0.5 mcg/kg/min IV infusion, may increase by 0.5-1 mcg/kg/min q3-5min PRN  

    Usual range: 1-5 mcg/kg/min IV infusion

    No more than 20 mcg/min

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