E Galileo Echo

LIS Interface
Specification

This document describes the specifications for the transfer of data between the Echo instrument
and a Laboratory Information System (LIS).
• Detailed list of contents
• Scope
• Definitions
• Connectivity
• Communication
• Echo ASTM message structure
• Echo ASTM record structure
• Examples
• References

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Galileo Echo LIS Interface Specification

Detailed List of Contents

Scope
Definitions
Connectivity
Serial
TCP/IP
Communication
Serial and TCP/IP Data Transfer
Establishment Phase (Link Connection)
Transfer Phase
Termination Phase (Link Release)
Data Characters
Echo ASTM Message Structure
Uploads
Results
Query
Downloads
Orders
Echo ASTM Record Structure
Header Record
Patient Record
Order Record
Field 5.4 – Instrument Assay Code Table
Field 6 – Priority Code Table
Field 12 – Action Code Table
Field 26 – Report Type Table
Result Record
Field 3.4 – Analyte Code Table
Field 4 – Measurement Values Table
Field 9 – Result Status Code Table
Request Information Record
Comment Record
Terminator Record
Field 3 – Termination Code Table
Examples
Group_Screen
Crossmatch
Donor
Query
Order
References

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Scope
This document describes the specifications for the transfer of data between the Echo instrument
and a Laboratory Information System (LIS). To ensure industry standardization, the Echo follows
LIS1-A – Standard Specification for Low-Level Protocol to Transfer Messages between Clinical
Laboratory Instruments and Computer Systems (formerly ASTM E1381-02) for electronic data
transmission and incorporates LIS2-A2 – Specification for Transferring Information between
Clinical Laboratory Instruments and Information Systems (formerly ASTM E1394-97) for the
structure of the data being transferred.

Definitions
Field – One specific attribute of a record that may contain aggregates of data elements further
refining the basic attribute.
Component field – A single data element or data elements that express a finer aggregate or an
extension of data elements that precede it.
Message – A textual body of information consisting of a header (H) record through a message
terminator (L) record.
Record – An aggregate of fields describing one aspect of the complete message.
Download – Data transmitted from a computer system (LIS) to a clinical instrument (Echo).
Upload – Data transmitted from a clinical instrument (Echo) to a computer system (LIS).

Connectivity
Two methods of connectivity are supported by the Echo—serial transfer and TCP/IP socket
transfer. This section describes both methods, each of which supports the LIS1-A low-level
communication protocol.

Serial
Serial connection to the Echo instrument is made using a DB-9 pin connector. Table 1 describes
the connector contact assignments.

Direction
Contact No. EIA Circuit Description Instrument LIS
1 … Shield … No Connection
2 BA Transmitted Data Output Input
3 BB Received Data Input Output
5 AB Signal Ground … …
Table 1 – Connector Contact Assignments for RS 232 D Serial Binary Data Exchange

The default serial communication port is COM2, and it uses the defaulted settings described in
Table 2.

Baud Rate 9600

Data Bits 8
Parity None
Stop Bits 1
Table 2 – Default COM port settings

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The serial mode of operation is a one-way transfer of information with alternate supervision.
Information flows in one direction at a time. Replies occur after information is sent, never at the
same time. It is a simplex stop-and-wait protocol.

TCP/IP
The Echo uses a standard RJ-45-style connector for TCP/IP communication. Detailed
requirements of an interconnecting cable are not defined, but good engineering practice should
be followed in selecting the cable and connectors. Low-capacitance cable and shielded
connectors may be necessary to suppress electromagnetic interface (EMI). Appropriate
connector locking hardware should be used at the conforming connectors.
The data transmission rate for the Echo conforms to a speed of 100Mbps.
The standard framework for TCP/IP network implementation is generally referred to as “socket”
implementation. The normal implementation of a socket-based communication protocol is
asymmetric. One end is considered a “server” providing service to the other end, which is
considered a “client.” Under this client/server paradigm, the LIS is defined as the “server” and
the Echo is defined as the “client.” Both must initially create sockets and bind their local Internet
addresses to their socket. The LIS, as the server, offers a socket for connection. The Echo, as
the client, is independently configurable for both socket and IP address (to facilitate use of
server-defined socket numbers and IP addresses), and requests a connection to the offered
socket.
Due to the harmful nature of viruses, worms, and other network anomalies, it is strongly
recommended that a firewall device be placed between the Echo instrument and the facility
network to protect against the malicious threats of networking. The Echo instrument connects to
the firewall device, which in turn is connected to the facility network. A firewall device is a
hardware component that will restrict access between the Echo instruments and the facility
network to block unwanted use or abuse, and a firewall is only necessary for Ethernet (TCP/IP)
connectivity. The Cisco PIX® 501 is the recommended device to be implemented.

Communication
Serial and TCP/IP Data Transfer
There are three distinct phases in transferring information between the Echo instrument and the
LIS. In each phase, one system directs the operation and is responsible for continuity of the
communication. The three phases assure that the actions of the sender and the receiver are
coordinated. The three phases are establishment, transfer, and termination. Although they are
briefly described here as an overview, the LIS-1A specification should be reviewed for complete
details. Any variance of the LIS-1A specification is described in the following section.

Establishment Phase (Link Connection)

The establishment phase determines the direction of information flow and prepares the receiver
to accept information. The Echo will notify the LIS receiver that information is available under the
following circumstances: sample loading and result availability.
Upon loading samples onto the Echo, the instrument will initiate the establishment phase to
notify the LIS that query information is available. After the Echo determines that the link is in a
neutral state, it will transmit the <ENQ> transmission control character to the LIS. The Echo will
ignore all responses other than <ACK>, <NAK>, and <ENQ>. If the LIS responds with the <ACK>
transmission control character, the establishment phase ends and the transfer phase begins.
Upon result availability, the instrument will initiate the establishment phase to notify the LIS that
result information is available. After the Echo determines that the link is in a neutral state, it will
transmit the <ENQ> transmission control character to the LIS. The Echo will ignore all responses
other than <ACK>, <NAK>, and <ENQ>. If the LIS responds with the <ACK> transmission control
character, the establishment phase ends and the transfer phase begins.

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At no time will the Echo respond to unsolicited messages. The expectation is that messages
containing order information will follow a query made to the LIS. The Echo will maintain the
connection in an active state for 15 seconds following a query to allow for a reply. After this time
is elapsed, the Echo no longer monitors the data link state.

Transfer Phase
During the transfer phase, the Echo transmits and receives messages to and from the LIS. The
transfer phase will continue until all messages are sent. Messages are sent and expected to be
received in frames, with each frame containing a maximum of 247 characters. Messages longer
than 240 characters are divided between two or more frames. Every message must begin a new
frame. A frame is one of two types—an intermediate frame or an end frame. The frame structure
is illustrated in Table 3; however, further explanation on the structure of the frame, including how
the frame number and checksum are calculated, can be found in the LIS1-A specification.

Intermediate Frame End Frame

<STX> FN text <ETB> C1 C2 <CR><LF> <STX> FN text <ETX> C1 C2 <CR><LF>

Where
<STX> Start of Text transmission control character
FN Single digit Frame Number 0 to 7
Text Data Content of Message
<ETB> End of Transmission Block transmission control character
<ETX> End of Text transmission control character
C1 Most significant character of check sum 0 to 9 and A to F
C2 Least significant character of checksum 0 to 9 and A to F
<CR> Carriage Return ASCII character
<LF> Line Feed ASCII character
Table 3 – Frame Structure

The Echo follows the rules outlined for acknowledgements to each frame. An <ACK> signifies
that the last frame was received successfully and indicates readiness to receive another frame. A
<NAK> signifies that the last frame was not successfully received and indicates readiness to
receive the frame again. An <EOT> signifies the last frame was received successfully, but an
interrupt is requested.

Termination Phase (Link Release)

The termination phase returns the data link to the clear or neutral state. The Echo will notify the
LIS that all messages have been sent by sending the <EOT> transmission control character. At
this point, the Echo will regard the data link to be in a neutral state. Upon receiving <EOT>, the
LIS should also regard the data link to be in the neutral state.

Data Characters
All data will be represented as eight-bit, single-byte, coded graphic character values as defined
in ISO 8859-1:1987. The eight-bit values, within the range from 0 to 127 of ISO 8859-1987
correspond to the ASCII standard character set. Values from 0 to 31 are disallowed with the
exception of 7 (BEL), 9 (Horizontal Tab), 11 (Vertical Tab), and 13 (CR), where 13 is reserved as
a record terminator. Values from 32 to 126 and from 128 to 254 are allowed. Values 127 and 255
are also not allowed.
Allowed characters: 7, 9, 11, 12, 13, 32-126, 128–254
Disallowed characters: 0–6, 8, 10, 14-31, 127, 255
All records are to be terminated with character 13 (CR).
The message structure and the record structure are detailed in the sections that follow.

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Echo ASTM Message Structure

The Echo instrument supports both uploads to an LIS and downloads from an LIS. The following
outlines the records for uploads and downloads.

Uploads
Results
Messages will contain the Header (H) record, Patient (P) record, Order (O) record, Result (R)
record, and the Terminator (T) record. The records will appear in the following manner:
H
P|1
O|1
R|1
R|2
R|n…
O|n
R|n
L
Note: Result messages will contain one patient per message, but they may contain multiple
order and result records per patient record.

Query
Messages will contain the Header record (H), Request for Information (Q) record, and the
Terminator (T) record. The records will appear in the following manner:
H
Q|1
Q|2
Q|n…
L

Downloads
Orders
Messages should contain the Header (H) record, Patient (P) record, Order (O) record, Comment
(C) record (required for XM orders), and the Terminator (T) record. The records should appear in
the following manner:
H
P|1
O|1
C|1
O|2
C|1
O|n…
P|n
L
Note: Multiple orders per patient and multiple patient records per message can be received.
Only one comment record per order record is expected.

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Echo ASTM Record Structure

For the tables in this section describing record structure, the following information applies:
• If a field is expected to contain multiple components, the Comp column will provide
reference to the component number.
• The Req column provides whether a field is required for uploads (U), downloads (D),
both (B), or if it is optional (O). If blank, then the field is not supported by the Echo.

Header Record
Field Comp Field/Component Name Req Description on use
1 Record type ID B H
The character H identifies the record as the header record.
2 Delimiter Definition B | - field delimiter
\ - repeat delimiter
^ - component delimiter
& - escape character
Note: The five characters that immediately follow the H (the
header ID) define the delimiters to be used throughout the
subsequent records of the message. A field delimiter follows
these characters to separate them from subsequent fields.
The first six (6) characters of the header record will appear as
follows: H|\^&|
3 Message Control ID
4 Access Password
5 Sender Name or ID B Echo
Instrument will send Echo as the Sender Name/ID.
Instrument will accept the ID that the LIS sends.
6 Sender Street Address
7 Reserved Field
8 Sender Telephone
9 Characteristic of Sender
10 Receiver ID B Echo
Instrument will send the configurable LIS ID.
Instrument will expect Echo when receiving messages.
11 Special Instructions
12 Processing ID
13 ASTM Version No. B LIS2-A2
14 Date and time of message B YYYYMMDDHHMMSS

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Patient Record
Field Comp Field/Component Name Req Description on use
1 Record Type ID B P
The character P identifies the record as the patient record.
2 Sequence Number B 1, 2, 3, n…
The number used defines the nth occurrence of the patient
record.
3 Practice Assigned ID O Medical Record Number
4 Laboratory Assigned ID
5 Patient ID No. 3
6 Patient Name O Last Name^First Name^Middle Name
6.1 Last Name O Patient Last Name
6.2 First Name O Patient First Name
6.3 Middle Name or Initial O Patient Middle Name (or Initial)
7 Mothers maiden name
8 Birthdate O YYYYMMDD or YYYYMMDDHHMMSS
9 Patient Sex O M, F, or U
10 Patient Ethnic origin
11 Patient Address
12 Reserved Field
13 Patient Tel Number
14 Attending Physician
15 Special Field 1
16 Special Field 2
17 Patient Height
18 Patient Weight
19 Patient’s Diagnosis
20 Patient Active Medicines
21 Patient’s Diet
22 Practice Field No. 1
23 Practice Field No. 2
24 Admission & Discharge
25 Admission status
26 Location
27 Alt. Diagnosis
28 Alt. Diagnosis Code
29 Patient Religion
30 Marital Status
31 Isolation Status
32 Language
33 Hospital Service
34 Hospital Institution
35 Dosage category

Note: The Echo does not authenticate nor verify the Patient Demographics received in fields 3,
6, 8, and 9. The instrument will simply return the values that were received from the LIS.

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Order Record
Field Comp Field/Component Name Req Description on use
1 Record type ID B O
The character O identifies the record as the order record.
2 Sequence Number B 1, 2, 3, n…
The number used defines the nth occurrence of the order
record at a particular hierarchical level and is reset to 1
whenever a patient record of greater hierarchical significance
is transmitted.
3 Specimen ID B Sample Accession Number
4 Instrument Specimen ID
5 Universal Test ID ^^^Assay Code
5.1 Universal Test ID Reserved by standard
5.2 Universal Test ID Name Reserved by standard
5.3 Universal Test ID Type Reserved by standard
5.4 Instrument Code B Instrument Assay Code
See Instrument Assay Code Table
6 Priority B R (See Priority Code Table)
7 Request Order Date
8 Specimen Collection Date
9 Collection End Time
10 Collection Volume
11 Collector ID
12 Action Code D N (See Action Code Table)
13 Danger Code
14 Relevant Clinical Inf.
15 Date specimen received
16 Specimen Descriptor B Type^Source
16.1 Specimen Type B Blood
16.2 Specimen Source B Patient or Product
Note: Patient is used when sample is from a patient; Product
is used when sample is from a donor unit or product.
17 Ordering Physician
18 Physician Tel No.
19 User Field 1
20 User Field 2
21 Laboratory Field 1
22 Laboratory Filed 2
23 Report Date Time
24 Instrument Charge
25 Instrument Section ID
26 Report Type O Y, Z (See Report Type Table)
27 Reserved Field
28 Location or Ward
29 Infection Flag
30 Specimen Service
31 Specimen Institution

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Field 5.4 – Instrument Assay Code Table

Assay Codes Description

ABOD Full Forward and reverse blood type with Rh determination

ABOD Long Forward and reverse blood type with Rh determination

Neonate Forward blood type

Donor Long Forward blood type for confirmation of donor units

Donor Short Forward blood type for confirmation of donor units

ABOD Check Forward blood type

ABOD Check
Forward blood type with Rh determination and 3-Cell screen
Screen

ABOD Check2 Forward blood type

ABOD Check2
Forward blood type with Rh determination and 3-Cell screen
Screen

Ag_CcEeK Detection of the C, c, E, e, and Kell antigens

Ag_CcEeK2 Detection of the C, c, E, e, and Kell antigens

Ag_C RH2 Detection of the C (RH2) antigen

Ag_c RH4 Detection of the c (RH4) antigen

Ag_E RH3 Detection of the E (RH3) antigen

Ag_e RH5 Detection of the e (RH5) antigen

Ag_Kell Detection of the Kell antigen

ABOD Full
Forward and reverse blood type with Rh determination and 3-Cell screen
Screen

ABOD Long
Forward and reverse blood type with Rh determination and 3-Cell screen
Screen

Screen Three cell antibody screen

Ready ID Antibody identification panel

Extend I Extended antibody identification panel

Extend II Extended antibody identification panel

Crossmatch IgG crossmatch

DAT Direct Antiglobulin Test

Weak D Weak D determination

Autocontrol Autocontrol for agglutination

Note: Assay Codes are subject to change.

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Field 6 – Priority Code Table

Code Description Echo Supported
S Stat
A As soon as possible
R Routine Y
C Callback
P Preoperative

Field 12 – Action Code Table

Code Description Echo Supported
C Cancel request for the battery or tests named
A Add the requested tests or batteries to the existing specimen
with the patient and specimen identifiers and date-time given in
this record
N New requests accompanying a new specimen Y
P Pending Specimens
L Reserved
X Specimen or test already in process
Q Treat specimen as a Q/C test specimen

Field 26 – Report Type Table

Code Description Echo Supported
O Order record; user asking that analysis be performed
C Correction of previously transmitted results
P Preliminary results
F Final results
X Order cannot be done, order cancelled
I In instrument pending
Y No order on record for this test (in response to query) Y
Z No record of this patient (in response to query) Y
Q Response to query (this record is a response to a request-
information query

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Result Record
Field Comp Field/Component Name
1 Record type ID
2 Sequence Number
3 Universal Test ID
3.1 Universal Test ID
3.2 Universal Test ID Name
3.3 Universal Test ID Type
3.4 Instrument Analyte Code
4 Measurement Value
4.1 Original Result Value
4.2 Edited Result Value
4.3 Measured Value
5 Units
6 Reference Range
7 Result Abnormal Flags
8 Nature of Abnormality
9 Result Status
10 Date of Change in Instrument
11 Operator Identification
12 Date/Time test started
13 Date/Time test completed
14 Instrument Identification
E–12
Req Description on use
U R
The character R identifies the record as the result record.
U 1, 2, 3, n…
The number used defines the nth occurrence of the result
record at a particular hierarchical level and is reset to 1
whenever an order record of a greater hierarchical
significance is transmitted.
U ^^^Analyte Code
Reserved by standard
Reserved by standard
Reserved by standard
U Instrument Analyte Code
See Analyte Code Table
U Original Reaction^Edited Reaction^Measured Value
If providing well results, this field is divided into components
as described in 4.1, 4.2, and 4.3. If the Analyte code
indicates an interpretive value, only component 4.1 will be
populated.
See Measurement Value Table for possible values
U Original instrument reaction
U User edited reaction
U Instrument measured reaction
U F (See Result Status Code Table)
U Operator ID
U YYYYMMDDHHMMSS
U Instrument serial number
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Field 3.4 – Analyte Code Table

Assay Code Analyte Codes
Rh Ctrl, Anti-A, Anti-B, Anti-AB, Anti-D1, Anti-D2, A1 Cells, B Cells, ABOD
ABOD Full
Full Interp
Anti-A, Anti-B, Anti-D1, Anti-D2, A1 Cells, A2 Cells, B Cells, O Cells, ABOD
ABOD Long
Long Interp
Neonate Rh Ctrl, Anti-A, Anti-B, Anti-AB, Anti-D1, Anti-D2, Neonate Interp
Donor Long Rh Ctrl, Anti-A, Anti-B, Anti-AB, Anti-D1, Anti-D2, Donor Long Interp
Donor Short Rh Ctrl, Anti-A, Anti-B, Anti-D, Donor Short Interp
ABOD Check Rh Ctrl, Anti-A, Anti-B, Anti-D, ABOD Check Interp
ABOD Check ABOD Check: Rh Ctrl, Anti-A, Anti-B, Anti-D, ABOD Check Interp
Screen Screen: Screen 1, Screen 2, Screen 3, Pos Ctrl, Screen Interp
ABOD Check2 Rh Ctrl, Anti-A, Anti-B, Anti-D, ABOD Check2 Interp
ABOD Check2 ABOD Check2: Rh Ctrl, Anti-A, Anti-B, Anti-D, ABOD Check2 Interp
Screen Screen: Screen 1, Screen 2, Screen 3, Pos Ctrl, Screen Interp
Ag_CcEeK Rh Ctrl, Anti-C, Anti-c, Anti-E, Anti-e, Anti-K, Ag_CcEeK Interp
Ag_CcEeK2 Rh Ctrl, Anti-C, Anti-c, Anti-E, Anti-e, Anti-K, Ag_CcEeK2 Interp
Ag_C RH2 Rh Ctrl, Anti-C, Ag_C RH2 Interp
Ag_c RH4 Rh Ctrl, Anti-c, Ag_c RH4 Interp
Ag_E RH3 Rh Ctrl, Anti-E, Ag_E RH3 Interp
Ag_e RH5 Rh Ctrl, Anti-e, Ag_e RH5 Interp
Ag_Kell Rh Ctrl, Anti-K, Ag_Kell Interp
ABOD Full: Anti-A, Anti-B, Anti-AB, Anti-D1, Anti-D2, A1 Cells, B Cells, ABOD
ABOD Full Full Interp
Screen
Screen: Screen 1, Screen 2, Screen 3, Pos Ctrl, Screen Interp
ABOD Long: Anti-A, Anti-B, Anti-D1, Anti-D2, A1 Cells, A2 Cells, B Cells, O
ABOD Long Cells, ABOD Long Interp
Screen
Screen: Screen 1, Screen 2, Screen 3, Pos Ctrl, Screen Interp
Screen Screen 1, Screen 2, Screen 3, Pos Ctrl, Screen Interp
R-ID 1, R-ID 2, R-ID 3, R-ID 4, R-ID 5, R-ID 6, R-ID 7, R-ID 8, R-ID 9, R-ID 10,
Ready ID
R-ID 11, R-ID 12, R-ID 13, R-ID 14, Pos Ctrl, Neg Ctrl, Ready ID Interp
E-I 1, E-I 2, E-I 3, E-I 4, E-I 5, E-I 6, E-I 7, E-I 8, E-I 9, E-I 10, E-I 11, E-I 12, E-I
Extend I
13, E-I 14, Pos Ctrl, Neg Ctrl, Extend I Interp
E-II 1, E-II 2, E-II 3, E-II 4, E-II 5, E-II 6, E-II 7, E-II 8, E-II 9, E-II 10, E-II 11, E-II
Extend II
12, E-II 13, E-II 14, Pos Ctrl, Neg Ctrl, Extend II Interp
Crossmatch Donor, IgG XM, Ind Ctrl, Crossmatch Interp
DAT DAT Rxn, Ind Ctrl, DAT Interp
Weak D Anti-D, Ind Ctrl, Weak D Interp
Autocontrol Auto Rxn, Rh Ctrl, Auto Interp

Note: The sequence of the Analyte Codes in the Upload Messages is not fixed.
Note: Analyte Codes are subject to change.

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Field 4 – Measurement Values Table

Type Component 4.1 Component 4.2 Component 4.3
Reactions 0, 1+, 2+, 3+, 4+, ?, 0, 1+, 2+, 3+, 4+, ?, 0 – 100
C, H, Q, M, R, U, X C, H, Q, M, R, U, X
Value Legend:
? Questionable
C Control Failure
H Hemolyzed or Sample Interference
Q QC Failure
M Monolayer Verification Error
R Reagent Verification Error
U Undetermined Failure
X Empty Well
Type Component 4.1
Grouping A Pos, A Neg, A NTD, B Pos, B Neg, B NTD, AB Pos, AB Neg, AB NTD,
Interpretations O Pos, O Neg, O NTD, NTD NTD, NTD Pos, NTD Neg, Ctrl Fail, QC
Failure, Invalid
Screen Positive, Negative, No Int, Invalid, Ctrl Fail, QC Failure
DAT Interpretations Positive, Negative, No Int, Invalid, Ctrl Fail
Crossmatch IgG Comp (Check ABO Comp), Incompatible, No Int, Invalid, Ctrl Fail
Interpretations
Phenotyping C+, C-, c+, c-, E+, E-, e+, e-, K+, K-, combinations of
Interpretations C+c+E+e+K+, No Int, Invalid, Ctrl Fail, QC Failure
Weak D Positive (Perform DAT Assay), Negative, No Int, Invalid, Ctrl Fail, QC
Interpretations Failure
Antibody Panel Complete, Invalid, Ctrl Fail
Interpretations
Autocontrol Positive, Negative, No Int, Invalid, Ctrl Fail
Interpretations

Note: Result/Interpretation text is subject to change.

Field 9 – Result Status Code Table

Code Description Echo Supported
C Correction of previously transmitted results
P Preliminary results
F Final results Y
X Order cannot be done
I In instrument, results pending
S Partial results
M This result is a MIC level
R This result was previously transmitted
N This result record contains necessary information to run a new
Q This result is a response to an outstanding query
V Operator verified/approved result
W Warning: validity is questionable
* Feature proposed for a future release of the Echo software.

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Request Information Record

Field Comp Field/Component Name Req Description on use
1 Record type ID U Q
The character Q identifies the record as the query record
2 Sequence Number U 1, 2, 3, n…
The number used defines the nth occurrence of the query
record
3 Starting Range ID U Accession Number
4 Ending Range ID
5 Universal Test ID U ALL
6 Nature of Request Time Limits
7 Beginning Request Results Date
and Time
8 Ending Request Results Date and
Time
9 Requesting Physician
10 Physician Tel Number
11 User Field No. 1
12 User Field No. 2
13 Request Information Status
Codes

Comment Record
Field Comp Field/Component Name Req Description on use
1 Record type ID D C
The character C identifies the record as a comment record.
2 Sequence Number D 1, 2, 3, n…
The number used defines the nth occurrence of the query
record
3 Comment Source D L
4 Comment Text D Donor^Actual Unit Number
4.1 Comment Code D Donor
4.2 Comment Text D Actual donor or unit number identifier
5 Comment Type

Note: Comment record is required when ordering the Crossmatch assay.

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Terminator Record
Field Comp Field/Component Name Req Description on use
1 Record type ID B L
The character L identifies the record as the terminator record.
2 Sequence Number B 1
There will only be one terminator record per message.
3 Termination Code B N (See Termination Code Table)

Field 3 – Termination Code Table

Code Description Supported by
Echo
N Normal termination Y
T Sender aborted
R Receiver requested abort
E Unknown system error
Q Error in last request for information
I No information available from last query
P Last request for information processed

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Examples
Result
ABOD Full Screen
H|\^&|||Echo|||||LIS|||LIS2-A2|20060306164429
P|1|1171984|||Patient^Test||19590422|M
O|1|0651439A||^^^ABOD Full|R||||||||||Blood^Patient
R|1|^^^Rh Ctrl|0^0^0|||||F||brentp||20060306164429|M0002
R|2|^^^Anti-A|0^0^0|||||F||brentp||20060306164429|M0002
R|3|^^^Anti-B|3+^3+^45|||||F||brentp||20060306164429|M0002
R|4|^^^Anti-AB|3+^3+^45|||||F||brentp||20060306164429|M0002
R|5|^^^Anti-D1|3+^3+^29|||||F||brentp||20060306164429|M0002
R|6|^^^Anti-D2|3+^3+^40|||||F||brentp||20060306164429|M0002
R|7|^^^A1 Cells|2+^2+^17|||||F||brentp||20060306164429|M0002
R|8|^^^B Cells|0^0^0|||||F||brentp||20060306164429|M0002
R|9|^^^ABOD Full Interp|B Pos|||||F||brentp||20060306164429|M0002
O|2|0651439A||^^^Screen|R||||||||||Blood^Patient
R|1|^^^Screen 1|4+^4+^100|||||F||brentp||20060306164429|M0002
R|2|^^^Screen 2|4+^4+^99|||||F||brentp||20060306164429|M0002
R|3|^^^Screen 3|4+^4+^100|||||F||brentp||20060306164429|M0002
R|4|^^^Pos Ctrl|4+^4+^100|||||F||brentp||20060306164429|M0002
R|5|^^^Screen Interp|Pos|||||F||brentp||20060306164429|M0002
L|1|N

Crossmatch
H|\^&|||Echo|||||LIS|||LIS2-A2|20060309084558
P|1|1171984|||Patient^Test||19590422|M
O|1|0651439A||^^^Crossmatch|R||||||||||Blood^Patient
R|1|^^^Donor|R02460|||||F||brentp||20060309084558|M0002
R|2|^^^IgG XM|3+^3+^68|||||F||brentp||20060309084558|M0002
R|3|^^^Ind Ctrl|4+^4+^94|||||F||brentp||20060309084558|M0002
R|4|^^^Crossmatch Interp|Incomp.|||||F||brentp||20060309084558|M0002
L|1|N

Donor
H|\^&|||Echo|||||LIS|||LIS2-A2|20060310100612
P|1|||||||
O|1|FY72698||^^^Donor Short|R||||||||||Blood^Product
R|1|^^^Rh Ctrl|0^0^0|||||F||brentp||20060310100612|M0002
R|2|^^^Anti-A|0^0^0|||||F||brentp||20060310100612|M0002
R|3|^^^Anti-B|0^0^0|||||F||brentp||20060310100612|M0002
R|4|^^^Anti-D|3+^3+^24|||||F||brentp||20060310100612|M0002
R|5|^^^Donor Short Interp|O Pos|||||F||brentp||20060310100612|M0002
L|1|N

Query
H|\^&|||Echo|||||LIS|||LIS2-A2|20050222140243
Q|1|0651439A||ALL
Q|2|R02460||ALL
L|1|N

Galileo Echo Operator Manual ECO-001-101 (E) E–17

Galileo Echo LIS Interface Specification

Order
H|\^&|||LIS|||||Echo|||LIS2-A2|20050222140243
P|1|1171984|||Patient^Test||19590422|M
O|1|0651439A||^^^Crossmatch|R||||||N||||Blood^Patient
C|1|L|Donor^R02460
L|1|N

H|\^&|||LIS|||||Echo|||LIS2-A2|20050222140243
P|1|1171984|||Patient^Test||19590422|M
O|1|0651439A||^^^ABOD Full Screen|R||||||N||||Blood^Patient
L|1|N

H|\^&|||LIS|||||Echo|||LIS2-A2|20050222140243
P|1|
O|1|FY72698||^^^Donor Short|R||||||N||||Blood^Product
L|1|N

References
NCCLS. Standard Specification for Low-Level Protocol to Transfer Messages Between Clinical
Instruments and Computer Systems. NCCLS document LIS1-A [ISBN 1-56238-489-9]. NCCLS,
940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2003.
NCCLS. Specification for Transferring Information Between Clinical Laboratory Instruments and
Information Systems; Approved Standard—Second Edition. NCCLS document LIS2-A2 [ISBN 1-
56238-550-X]. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898
USA, 2004.

E–18 ECO-001-101 (E) Galileo Echo Operator Manual