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International Distributors

Meeting 2018
Workshops, presentations, business talk and more
No surprise - AZURA with the same performance as Ultimate 3000

No surprise
AZURA on par with UltiMate 3000 RS
AZURA vs. UltiMate
AZURA UHPLC System (998502200)

AZ U R A Au t o s a m p l e r AS 6 . 1 L 56.500* €
1000 bar 100 Hz
AZ U R A C o l u m n t h e r m o s t a t C T 2 . 1

AZ U R A D e t e c t o r D AD 6 . 1 L

AZ U R A P u m p P 6 . 1 L
1000 nm LPG

LightGuide UV Flow Cell Cartridge 2 µL

* W i t h o u t S o f t wa r e & P C
UltiMate™ 3000 RS LC System

W P S - 3 0 0 0 R S Au t o s a m p l e r 60.500* €
1000 bar 200 Hz
TCC-3000RS Column thermostat

D AD - 3 0 0 0 R S D e t e c t o r

LPG-3400RS Pump
800 nm LPG

S e m i a n a l yt i c a l f l o w c e l l 5 µ L

* W i t h o u t S o f t wa r e & P C
Technical comparison
DWELL VOLUME

550 µL 1100 µL

The difference in the dwell volumes results from the larger mixing chamber of the
thermal system, the 100 μL capillary on the autosampler valve
and the additional pre-column cooling.
DISPERSION VOLUME

14.5 µL 14.5 µL

Volume between injection system and


detection system without column
GRADIENT ACCURACY
0.2 mL/min
GRADIENT ACCURACY
1.0 mL/min
GRADIENT ACCURACY
2.0 mL/min
NOISE & DRIFT

15 µAU 17 µAU

< 0.1
mAU/h
CARRY OVER

Limit
0.01%

< 0.005 % < 0.005 %

Peak area percent of the blank after


injection of 2000 µg/mL caffeine.
Application
Determination of 2,6-dimethylaniline impurities
in lidocaine-containing dermal fillers

DMA

LOD

LOQ
Method parameter

1,8
Gradient Buffer ACN
mL/min

ESII 150 mm ID
5 µm
C18P length 4,6 mm

Injection
220 nm 23 °C 1 ppm
10 µL
Calibration

DMA mg/ mL
Level 1 0,010
Level 2 0,025
Level 3 0,030 R-Square or
0.9999 Correlation 0.9999
Level 4 0,050 Coeffecient
Level 5 0,100
Reproducibility

Peak
area

Peak
height Relative
Standard
< 1.0 % < 1.0 %
Deviation
Retention (RSD)
time
Chromatogram
1 ppm

0.001
mg/mL
LOD & LOQ

Signal Noise
Flow cell LOD [ppm] LOQ [ppm]
[mAU] [mAU]
UltiMate 7 mm, 5 µl 1.710 0.057 0.100 0.332
AZURA 10 mm, 10 µl 2.502 0.083 0.100 0.333
International Distributors
Meeting 2018
Workshops, presentations, business talk and more

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