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  • Immunoglobulin G

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    Jemuel Bucud Lagarto
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    The document discusses the five classes of antibodies (immunoglobulins): IgG, which is most prevalent and protects against pathogens while crossing the placenta; IgE, which is rare and triggers allergic reactions by binding to mast cells; IgD, which binds antigens to sensitize B cells; IgM, which is the largest and first produced during an immune response causing blood transfusion reactions; and IgA, which is secreted in mucus and other fluids to provide immunity.

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    The document discusses the five classes of antibodies (immunoglobulins): IgG, which is most prevalent and protects against pathogens while crossing the placenta; IgE, which is rare and triggers allergic reactions by binding to mast cells; IgD, which binds antigens to sensitize B cells; IgM, which is the largest and first produced during an immune response causing blood transfusion reactions; and IgA, which is secreted in mucus and other fluids to provide immunity.

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    10 views1 page

    Immunoglobulin G

    Uploaded by

    Jemuel Bucud Lagarto
    The document discusses the five classes of antibodies (immunoglobulins): IgG, which is most prevalent and protects against pathogens while crossing the placenta; IgE, which is rare and triggers allergic reactions by binding to mast cells; IgD, which binds antigens to sensitize B cells; IgM, which is the largest and first produced during an immune response causing blood transfusion reactions; and IgA, which is secreted in mucus and other fluids to provide immunity.

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    © All Rights Reserved
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    Immunoglobulin G (IgG)

    Most prevalent antibody in human body. It protects against fungi, bacteria, toxins etc. It
    can cross the placenta barrier and provide immunity to the fetus.

    Immunoglobulin E (IgE)
    Is the isotype of antibody that is rarest in the serum and is mostly found bound to mast
    cell and basophils via its Fc region and responsible for allergic reaction.

    Immunoglobulin D (IgD)
    Is an individual molecule on the surfaces of the B cells, where it can bind antigens in the
    extracellular fluid. This binding can play a role in the sensitization of the B cell involved.

    Immunoglobulin M (IgM)
    This is the largest class of antibody and the first to be produced during an immune
    response. IgMs are responsible for blood transfusion resaction in ABO blood groups system.

    Immunoglobulin A (IgA)
    It is the second most prevalent antibody. It is secreted through the mucous lining of the
    digestive tract, saliva, tears, ect. It is also found in colostrum, providing immunity to the new
    born.

    Prepared By:

    Jemuel Bucud Lagarto

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