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Behavioral Sciences Pharmacology

Shan Nanji
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Behavioral Science Pharmacology

Tricyclic Anti-Depressant's

n MOA:
n  Blocks __________________
n  Blocks __________________Receptors
n  Interferes with AV Nodal Conduction
n  Strongly __________________
n  Anti Histamine

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

Tricyclic Anti-Depressant's
n  Amitriptyline – First line for chronic pain
n  AMY-TRIPT-yline
n  __________________ – Second line for bed wetting
n  Nortriptyline – Least amount of effects on blood pressure
n  NOR-triptyline
n  Desipramine – Least amount of side effects over all
n  DESI-pramine
n  __________________ – Second line for OCD

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

Tricyclic Anti-Depressant's
n  S/E:
n  Coma
n  Cardiotoxicty
n  Convulsions

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

Stimulants:
n MOA:
n  Blocks CC Reuptake

n  Clinical Use:

n  ADHD
n  Narcolepsy
n  Appetite Suppression

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

Stimulants:
n  S/E:
n  Hypertension
n  Tachycardia
n  Anorexia

n Methylphenidate
n Dextroamphetamine
n Methamphetamine

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

n SSRI’s
n Sertraline – PTSD
n SIR-traline
n Fluoxetine - Depression
n  __________________ – Social Phobia
n  DOC Pre-mature Ejaculation
n  __________________ – Helps restore
memory post stroke

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

n SSRI’s
n S/E:
n  Anorgasmia!
n  Serotonin Syndrome
n  Hyperthermia
n  Confusion
n  Diarrhea
n  Seizures
n  Cardiovascular Collapse

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

n SNRI’s
n Venlafaxine - Depression
n  __________________– Depression
n  More effect on NE

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

n Maprotiline
n MOA:
n  Blocks NE Reuptake

n  S/E:
n  Orthostatic HypOtension
n  Sedation

Shan Nanji - NanjiMD@gmail.com

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Behavioral Science Pharmacology

n Buproprion – For Smoking Cessation

n  increases __________________

n Buspirone – For Anxiety

n BUS-pir-ON-e

n Benzodiazepines – Increase the ____________ of Cl- Channels

n  __________________ – Shortest Acting
n  Flourazepam – Longest Acting
n  __________________ – Second line for absence seizures
n  Triazolam – Puts you to sleep
n  __________________ – Maintains sleep
Shan Nanji - NanjiMD@gmail.com
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Midazolam…

45 minutes anterograde amnesia…

Shan Nanji - NanjiMD@gmail.com

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Sleep Pharm…

n Triazolam - Helps you go to sleep

n Tamazepam – Helps maintain sleep
n  Which helps increase REM but can cause priapism?

- Trazodone

Shan Nanji - NanjiMD@gmail.com

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Phenothiazines

n Low Potency
n  __________________ – Decreases BP by blocking Alpha 1
n  __________________ – Can cause iris pigmentation

Shan Nanji - NanjiMD@gmail.com

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Phenothiazines

n High Potency
n Perchlorperazine – Anti-emetic in adults
n __________________– Anti-emetic in children
n Fluphenazine – Anti-psychotic, depot form
n Trifluoperazine

n  S/E:
n  Extrapyramidal System

Shan Nanji - NanjiMD@gmail.com

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Antipsychotics: Butrephenons

n High Potency
n Haloperidol

Shan Nanji - NanjiMD@gmail.com

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Antipsychotics: Butrephenons

n Atypicals
n  __________________ – Gold standard
n  S/E:
n  Agranulocytosis
n  Neutropenia
n  Seizures

n Olanzapine
n  S/E :
n  __________________

Shan Nanji - NanjiMD@gmail.com

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Antipsychotics: Butrephenons

n Atypicals
n  __________________
n  S/E:
n  Increases PRL

n Quetiapine
n  S/E:
n  __________________

Shan Nanji - NanjiMD@gmail.com

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Antipsychotics: Butrephenons

n Atypicals
n Ziprasidone
n  S/E:
n  Prolonged QT Possible

n Aripiprazole
n  S/E:

Shan Nanji - NanjiMD@gmail.com

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Monoamine Oxidase Inhibitors

“MAO-I”

n MOA:
n  Block Mono-Amine Oxidase
n  Increase Serotonin, NE, and Dopamine

n MAOi- A
n  __________________
n Isocarboxacid
n  __________________

Shan Nanji - NanjiMD@gmail.com

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Monoamine Oxidase Inhibitors

“MAO-I”

n MAOi-B
n Selegeline

Shan Nanji - NanjiMD@gmail.com

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Mood Stabilizers

n  __________________
n  First Blocks Na
n  Then blocks Ca

n  Fetal S/E:

n  __________________
n  __________________
n  Bone Marrow Supression

Shan Nanji - NanjiMD@gmail.com

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Mood Stabilizers

n Lithium
n  Blocks __________________

n  Fetal S/E:

n  Epsteins Anomaly
n  Right Atrium is __________________
n  Left Heart __________________
n  __________________ Blood Pressure

Shan Nanji - NanjiMD@gmail.com