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Toxicology NRC 11203

Activity Nº2 (Score 57% First Term)

1. (2.5 Points) Regarding de History of the Toxicology, match the items on the
right to the items on the left (Look at the example):

A. Poisonous frog (_H_) Biochemistry, Chemistry, Pharmacology, Medicine


B. Etymology of toxicology (_C_) Cantarella – Aquetta di Perugia
C. The Borgia Family (_F_) Forensic Toxicology, Clinical Toxicology, Environmental Toxicology,
Occupational Toxicology
D. Ebers Papyrus (_B_) Toxicon - Logia
E. Spanish physician: Orfila (_I_) Madame Lafarge: convicted of murdering her husband by arsenic
poisoning
F. Divisions-Branches of (_E_) Lead Poisoning-Miners
toxicology
H. Overlapping disciplines with (_D_)Different kind of poisons used with abortive purposes (Hemlock –
Toxicology Aconite – Opium)
I. Hippocrates off Kos (_A_) Poisonous berries

2. (2.5 Points) Explain the following statement, and give an example related to
the normal life. Use your own words, any kind of plagiarism won’t be
accepted “All substances are poisons; there is one that is not a poison. The right
dose differentiates a poison and a remedy”. NOT MORE THAN 250 WORDS.

For me the statement states that:

When the dose is not correct; when the dose of a medicine is exceeded, this would
no longer be a remedy if not a poison.

On the other hand, if the dose ingested is low, it will not cause harmful effects.

When the dose is correct, the remedy becomes effective.

Example:

A poisoning with paracetamol (Acetaminophen)


Acetaminophen is regularly an effective and safe drug, but it is not harmless if
ingested correctly.

It is poisonous, when the prescribed dose is taken several times. The dose of
paracetamol to cause gravity is not accidental, it is because it was ingested
intentionally.

Translation in Spanish

Para mí, la declaración dice que:

Cuando la dosis no es correcta; Cuando se excede la dosis de un medicamento,


esto ya no sería un remedio si no un veneno.

Por otro lado, si la dosis ingerida es baja, no causará efectos nocivos.

Cuando la dosis es correcta, el remedio se hace efectivo.

Ejemplo:

Envenenamiento con paracetamol (acetaminofeno)

El acetaminofeno es regularmente un medicamento efectivo y seguro, pero no es


inofensivo si se ingiere correctamente.

Es venenoso, cuando la dosis prescrita se toma varias veces. La dosis de


paracetamol para causar gravedad no es accidental, es porque se ingirió
intencionalmente.

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