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MICROBIOLOGY/ GENERAL (IV) 26. Virus quantification is done by


A. Egg inoculation B. Hemadsorption
Match the following: C. Plaque assay D. Electron microscopy
27. Pigment production of Staphylococcus aureus is enhanced in
Organism - Selective / Enrichment media A. Milk agar B. Ludlam's medium
C. Pike's medium D. Blood agar
1. Plating media for v cholera - TCBS media 28. HIV virus contains
2. Legionella - BCYE media A. Single stranded DNA B. Single Stranded RNA
3. Bordetella - Border Gengou C. Double Stranded DNA D. Double Stranded RNA
Medium 29. Causative agent of malaria
4. M Tuberculosis - LJ medium A. Protozoa B. Mosquito
5. S Aureus - Mannitol Salt Agar C. Bacteria D. Virus
6. C. Diphtheriae - Loeffer’s serum slope 30. Window period in HIV infection
7. Bacillus Anthracis - PLET A. 1-2 weeks B. 4-8 weeks
( Polymyxin Lithium EDTA thallous acetate) C. 8-12 weeks D. > 12 weeks
8. Compylobacter - Skirrow’s medium 31. What is the sequence which a retrovirus follows on entering a host
9. Reiter’s Treponema - Smith Noguchi cell
Medium A. RNA-DNA-RNA B. RNA-DNA
10. Pseudomonas - Cetrimide Agar C. DNA-RNA D. DNA-RNA-DNA
32. The scientist who discovered the transmisssion of malaria by
11. Resolving power of microscope depends on all except: anopheline mosquito -
A. Refractive index of medium A. Laveran B.Paulmuller
B. Wavelength C. Ronald Ross D. Pampana
C. Diameter of aperture 33. Inclusion bodies of vaccinia is known as -
D. Focal length of objective lens A. Guarnieri bodies B. Negri bodies
12. Specificity of a screening test measures - C. Asteroid bodies D. Schuffiter dots
A. True positives B. False positives
C. False negatives D. True negatives 34. Kaposi sarcoma is caused by -
13. Lipschutz bodies are seen in - A. Human herpes virus-2 B. Human herpes virus-4
A. Hodgkin's disease B. Viral Hepatitis C. Human herpes virus-6 D. Human herpes virus-8
C. Herpes D. Influenza 35. Break bone fever is caused by
14. "Wildcat" is brand name of A. Yellow fever B. Japanese encephalitis
A. NiTi wire B. Braided Stainless steel Wire C. Dengue Fever D. KFD
C. Elgiloy wire D. TMA Wire 36. Best means of giving hepatitis B vaccine is -
15. The green elgiloy wire is A. Subcutaneous B. Intradermal
A. Resilient B. Semi-resilient C. Intramuscular deltoid D. Intramuscular gluteal
C. Ductile D. Soft and Easy to bend 37. Hepatitis C virus is a
16. All of the following are general properties of Viruses except A. Togavirus B. Flavivirus
A. May contain both DNA and RNA C. Filovirus D. Retrovirus
B. Form extracellular infectious particles 38. Bivalent HPV Vaccine contains which types
C. Heat labile D. Not affected by antibiotics A. Type 6,11 B. Type 6,16
C. Type 16, 18 D. Type 11,18
17. Capsid of viral structure is-
A. Extracellular infectious particle 39. Most common type of HPV associated with cervical cancer
B. Protein coat around nucleic acid A. 6,11 B. 5,8
C. Envelop around a virus D. None of the above C. 16, 18 D. 6, 8
18. In malaria, sexual cycle is - 40. Parvovirus causes
A. Sporozoite to gametocytes B. Gametocvtes to sporozoite A. Erythema infectiosuin B. Exanthema subitum
C. Occurs in human D. Responsible for relapse C. Roseola infantum D. Sixth disease
19. In malaria, pre-erythrocytic schizogony occurs in- 41. Slapped cheek sign is seen in -
A. Lung B. Liver A. Parvovirus B19 B. Exanthema subitum
C. Spleen D. Kidney C. Rot virus D. Mumps
20. Which of the following is not a function of school dental nurse 42. All belong to Picorna viruses except
A. Prophylaxis B. Oral examination A. Enterovirus 70 B. Coxsackie virus
C. Fluoride application D. Taking x-rays C. Rhinovirus D. Herpes simplex virus
21. Serum sickness is which type of reaction? 43. Mode of spread of enterovirus is?
A. Type 1 B. Type 2 A. Vector mediated B. Droplet infection
C. Type 3 D. Type 4 C. Faeco oral route D. Skin contact
22. Which is not a DNA virus 44. Herpangina is caused by
A. Parvovirus B. Papovavirus A. Adenovirus B. Enterovirus 72
C. Poxvirus D. Rhabdovirus C. Coxsackie virus A D. Coxsackie virus B

23. True about herpes virus is? 45. Enterovirus 72 is


A. Circular double stranded DNA virus A. Hepatitis A B. Hepaitis E
B. Linear double stranded DNA virus C. Hepatitis G D. Hepatitis C
C. Circular double stranded RNA virus 46. Diagnosis of polio -
D. Circular single stranded RNA virus A. Detection of polio virus in stool
24. Viruses can be isolated from clinical samples by cultivation in the B. Serology
following except - C. Limb wasting D. AFP
A. Tissue culture B. Embryonated eggs 47. Most common mode of transmission of polio virus
C. Animals D. Chemically defined media A. Droplet infection B. Fecal-oral route
C. Blood transfusion D. Vertical transmission
25. Influenza virus culture is done on 48. Not true about paramyxoviruses-
A. Chorioallantoic membrane B. Allantoic cavity A. Belong to family myxoviridae
C. Yolk sac D. All B. Are DNA viruses
C. Have linear nucleic acid D. Antigenically stable

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49. Influenza virus has 70. Acute hemorrhagic fever with renal involvement is caused by-
A. 5 segments of SS RNA B. 8 Segments of ds DNA A. KFD B. Yellow fever
C. 8 segments of ssDNA D. 8 segments of ssRNA C. Hanta virus D. JE
50. H1N1 is 71. Most common tumour caused by virus is -
A. Swine flu B. SARS A. Warts B. Carcinoma cervix
C Avian D. Chicken pox C. Nasopharyngeal carcinoma D. Lymphoma
51. Rash of chicken pox is - 72. Regarding Hepatitis E true is
A. Deep seated B. Centripetal distribution A. Occurs with Hepatitis B B. Single stranded DNA virus
C. Monomorphic D. Umblicated C. Occurs along with HIV
52. Following are true of kyasanur forest disease except D. Mortality increased in pregnancy
A. Transmitted by Soft tick B. Caused by retrovirus 73. Hepatitis E clinically resembles
C. Incubation Period is 3-8 days A. Hepatitis A B. Hepatitis B
D. Killed vaccine available C Hepatitis C D. Hepatitis D
53. Genetic reassortment is seen with 74. In Japanese Encephalitis, pigs acts as -
A. Astrovirus B. Herpes virus A. Amplifier B. Definitive host
C. Rotavirus D. Hepadena virus C. Intermediate host D. Any of the above
75. True about rotavirus vaccine-
54. All are associated with EBV except - A. Killed vaccine B. Given subcutaneous
A. Infectious mononucleosis C. Pentavalent vaccine
B. Nasopharyngeal carcinoma D. Should be given befor 5years
C. Oral hairy leukoplakia D. Epidermodysplasia
55. Hemorrhagic fever is caused bu 76. Hepatitis B vaccination is given to a patient. His serum will reveal
A. West-Mile fever B. Sandfly fever A. HBsAg B. Anti-HBsAg
C. Ebola virus D. All of the above C. IgM Anti-HBcAg and HBsAg
56. HCV is - D. IgM and IgG Anti-HBcAg
A. Enveloped RNA B. Nonenveloped RNA 77. False about antigen drift-
C. Nonenveloped positive strand RNA A. Causes pandemic
D. Enveloped negative strand RNA B. Occurs due to mutation
57. Most common cause of viral pneumonia in infant is- C. Occurs more frequently
A. Rhinovirus B. RSV D. Affected by previous antibodies
C. Reovirus D. CMV 78. H5N1 is a strain of -
58. First antibody to appear in hepatitis - A, Avian flu B. New vaccine against AIDS
A. IgManti-HBe B. IgG-anti-HBe C. Agent for Japanese encephalitis
C, IeM anti-HBc D. IgM anti-HBs D. Causes chickengunya fever
79. Which of the following antigen is found within the nuclei of infected
59. Commonest hcpatotropic virus causing increased chronic carrier hepatocytes and not usually in the peripheral circulation in Hepatitis B'
state is infection?
A. HEV B. HAV A. HBcAg B. HBcAg
C. HBV D. HCV C. Anti-HBc D. HBsAg
60. Trichuris trichura is
A. Round worm B. Whip worm 80. With which of the following of viral hepatitis infection in pegnancy,
C. Hook worm D. Thread worm the maternal mortality is highest -
61. Both intranuclear and cytoplasmic inclusion is seen in A. Hepatitis A B. Hepatitis B
A. Poxvirus B. Herpesvirus C. Hepatitis C D. Hepatitis E
C. Measles virus D. Mumps virus 81. Negri bodies are found in
62. Cowdry type A inclusion bodies are seen in A. Hypothalamus B. Hippocampus
A. HBV B. Herpesvirus C. Midbrain D. Medulla
C. Adenovirus D. Poxvirus 82. Oncogenic virus is
63. Sentinel lymph node is A. CMV B. VZV
A. Group of lymph nodes C. Polio virus D. EBV
B. First stop alone the route of Lymphatics 83. Which prion disease affect buman
C. A node that is skipped during distant metastasis A. Scrapic B. Madcow disease
D. Distant metastatic node C. Kuru
D. Bovine spongiform encephalopathy
64. Varicella zoster remains latent in 84. Which of the following wires is better choice if alignment is needed?
A. Lymphocytes B. Monocytes A. Nitinol B. TMA wire
C. Trigeminal ganglion D. Plasma cells C. Elgiloy wire D. Stainless steel wire
65. EBV action in nasopharynx is through- 85. Anti Malaria week
A. CD 3 B. Cd4 A. l-7th May B. 1-7th June
C. CD 8 D. CD 21 C. 1-7th July D. 1-7th August
66. Next to HBV, virus implicated in hepatocellular Ca is - 86. Chediak higashi syndrome, defect is-
A. HCV B. Herpes A. Fusion of lysosome B. T-cells Pattern
C. HAV D. HEV C. B-cells D. Complement

67. Which of the following is Calcivirus 87. A pregnant woman from bihar presents with hepatic
A. Hepatitis E B. Hepatitis B encephalopathy. The likely diagnosis -
C. Hepatitis C D. Hepatitis A A. Hep. E B. Hep. B
C. Sepsis D. Acute fatty liver of pregnancy
68. EB virus belong to which group 88. Presence of HBe Ag in patients with hepatitis indicates
A. Retrovirus B. Herpesvirus A. Simple carriers B. Late convalescence
C. RNA virus D. Poxvirus C. High infectivitv D. Carrier status
69. Dengue hemorrhagic fever is caused by -
A. Type I dengue virus 89. HDV is
B. Reinfection with same serotype of dengue virus A. SS RNA Virus B. SS-DNA virus
C. Reinfection with a different serotype of dengue virus C. SS DNA Virus D. DS-DNA virus
D. Infection in an immunocompromised host

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90. Most common route of spread of Hepatitis E is 111. Prions are


A. Sex B. Feco-oral A. Made up of bacterial and viral particles
C. Blood transfusion D. IV injections B. Immunogenic
91. Scalds are due to C. Infectious D. RNA particles
A. Chemicals B. Moist heat 112. Brick shaped virus
C. Dry heat D. High A. Chickeh pox B. Small pox
92. In transmission of malaria, mosquito bite transfers- C.CMV D. EBV
A. Sporozoite B. Merozoite 113. Prions consists of
C. Hypnozoite D.Gametocyte A. DNA and RNA B. DNA, RNA and Protein
93. Most sensitive diagnostic test for dengue is ? C. RNA and Protein D. Only proteins
A. IgM elisa B. Complement fixation test 114. Measles virus is -
C. Neutralization test D. Electron microscopy A. Paramyxovirus B. Orthomyxovirus
94. Hepatitis A is transmitted by C. Poxvirus D. Picomavirus
A. Blood route B. Inhalation 115. All are peripheral lymphoid organ except:
C. Feco-oral route D. All A. LN B. Spleen
95. Least reduction in primary stainless steel crown? C. MALT D. Thymus
A. Lingual B. Labial
C. Occlusal D. Proximal 116. Segmented genome is found in
A. Retrovirus B. Rotavirus
96. Causative organism of SARS C. Poliovirus D. Rhabdovirus
A. HINI B. Corona Virus 117. Lysogenic conversion is
C. Rotavirus D. RSV A. New properties in a bacterium due to integration of phase
97. Staphylococcus epidermidis B. Transfer of DNA from one bacterium to another by a bacteriophage
A. Coagulase positive C. Transfer of free DNA
B. Commonly involved in catheter associated urinary tract infection D. Transfer of genome during physical contact
C. Commonest cause of rheumatic fever 118. The chancer that a health worker gets HIV from an accident needle
D. Commonest cause of abscesses prick is
98. Owl eye intranuclear inclusion body is seen in ? A. 1% B. 10%
A. Herpes zoster B. Herpes simplex C. 95% D. 100%
C. CMV D. EBV 119. CMV retinitis in HIV occurs when the CD4 counts falls below
99. The role played by MHC 1 and 2 is to: A. 50 B. 100
A. Stimulate interleukin production C. 200 D. 150
B. Immunoglobulin class switch over
C. Transduce the signal to T-cell following antigen binding 120. Commonest helminthic infection in ADIS is
D. Presenting the antigen for recognition by T-cell A. Trichuris trichura
antigen binding receptors B. Strongyloides stercoralis
100. Forschheimer spot is seen in C. Enteroblus vermicularis D. Nector anenicanus
A. Measles B. Chicken pox 121. Which of the following hepatitis viruses is a DNA virus -
C. Erythema infectiosum D. Rubella A. Hepatitis C virus B. Hepatitis B virus
C. Delta agent D. Hepatitis E virus
101. The following is used in “Rule of nines” to estimate the body surface 122. DNA polymerase of HBV is encoded by which of the following-
in burns A. S gene B. C gene
A. Body weight B. Body surfaces area C. Pgene D. X gene
C. Dehydration D. A and B 123. In HIV wondow period indicates
102. Pulmonary capillary wedge pressure is measured using A. Time period between infection and onset of first symptoms
A. Foley's catheter B. Fogarty balloon catheter B. Time period between infection and detection of antibodies against HIV
C. Swan-Ganz catheter D. Arterial catheter C. Time period between infection and minimum multiplication of the
103. Acute Hepatitis B can be earliest diagnosed by organism
A. IgMantiHBcab B. Hbs Ag D. Time period between infection and maximum multiplication of the
C. IgC anti HBc abs D. AntiHBsAgab organism
104. Wasserman test is: 124. HIV can be detected and confirmed by
A. Agglutination test B. Precipitation test A Polymerase chain reaction (PGR)
C. Neutralization test D. Complement fixation B. Reverse Transcriptase – PCR
105. Ito’s test is for C. Real time PCR D. Mimic PCR
A. Leishmania donovani
B. Lymphogranuloma venerium 125. ELISA test when compared to western blot technique is
C. Chancroid D. Sarcoidosis A. Less sensitive, less specific B. More sensitive, More specific
106. Cultivable (in vitro) hepatitis virus is C. Less sensitive, more specific D. More sensitive, less specific
A. Hepatitis A B. Hepatitis B 126. Property of elution is found in
C. Hepatitis C D. Hepatitis D A. Myxovirus B. Togavirus
107. The most common presentation of congenital CMV infection is - C. Parvovirus D. Adenovirus
A. Hepatosplenomegaly B. Microcephaly 127. Phage typing can be done for
C. Cerebral calcification D. Chorioretinitis A. Salmonella B. Streptococcus
C. Shigella D. Pseudomonas
128. Small pox belongs to which class of poxviruses
108. Commonest complication of mumps is A. Parapoxvirus B. Capripoxvirus
A. Orchitis and oophritis B. Encephalitis Leporipox virus D. Orthopoxvirus
C. Pneumonia D. Myocarditis 129. Neurological complications following Rabies vaccine is common
109. Incubation period of HBV is with
A. 45 to 180 days B. 6 to 60 days A. HDCS Vaccine B. Chick embryo Vaccine
C. 10 days D. 10 hrs C. Semple Vaccine D. Duck Egg Vaccine
110. Composition of ZN stain arc all EXCEPT: 130. All are cultivable virus Except -
A. Basic fuchsin B. Acid fuchsin A. Rotavirus B. Enterovirus
C. Phenol D. Alcohol C. ECHO virus D. Coxsackie virus

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