Hypertension > Tth Report of the Joint National Committee on Detection, Evaluation, & of igh a? (JNC-7): Category Systolic (mmHg) Diastolic (r Normal <120 &<80 Pre-hypertension 120-139 0 80-89 Stage 1HPN 140-159 0 90-99 Stage 2 HPN 2160 Or> 100 8th Report of the Joint National Committee on Detection, Evaluation, & Treatment of High BP (JNC-8): Blood Pressure Stages Ere aera cg Hypertension > most common cardiovascular disorder + sustained BP > 130/>80 (systolic/ diastolic) » NOTE: PLEASE REMEMBER THE DIFFERENTIATION OF JNC VII AND JNC VIII CLASSIFICATIONTHINGS TO REMEMBER HYDRALAZINE causes SLE HYDRALAZINE AND METHYLDOPA are the drug of choices to treat hypertension in pregannt patients Na NITROPRUSSIDE is the DOC for hypertensive crisis/emergency Na NITROPRUSSIDE is associated with cyanide poisoning MINOXIDIL CAUSES HIRSUTISM CaCB is divided into 2..Dihydropyridines are those that ends in “DIPINE” and Non-dihydropyridines that includes diltiazem and verapamil. their difference is that dihydropyridines acts on the vessel only while non-dihydropyridine acts on the vessels and in the heart THINGS TO REMEMBER CLONIDINE- causes rebound hypertension on withdrawal METHYLDOPA - gives positives coombs tst that indicates presence of hemolytic anemia ALPHA - 1 BLOCKERS/CaCB/ACEI/A2RBS/VASODILATORS - ALL will act as antihypertensives via vasodialtion. ALL will exhibit reflex tachycardia. ALPHA - 1 BLOCKERS- will exhibit” FIRST DOSE PHENOMENON” meaning to say it will cause orthostatic hypotension after first dose ACEI causes coughing because of the increse of bradykinin ACE! is the DOC in hypertensive diabetics Direct Renin inhibitor is named as Aliskiren