Where does transcription occur in

Eukaryotes?
Nucleus
Where does replication occur in
Eukaryotes?
Nucleus
Where does translation occur in
Eukaryotes?
Cytoplasm
Where does transcription occur in
Prokaryotes?
Cytoplasm
Where does replication occur in
Prokaryotes?
Cytoplasm
Where does translation occur in
Prokaryotes?
Cytoplasm
AUG
Start Codon, Methionine
UAA, UAG, UGA
Stop Codon
Codon-Anticodon Relationship
 tRNA anticodons recognize
complementary codons in the mRNA,
which results in adding the correct
amino acid to a growing polypeptide
chain
Degenerate Code
Multiple codons encode for a single
amino acid due to wobble pairing
Wobble Pairing
Atypical base pairing between the third
nucleotide in the codon and anticodon
that allows tRNAs to recognize more
than one codon
Missense Mutation
A point mutation in the DNA that results
in the change in a single amino acids
Silent Mutation
A point mutation that does not change
the amino acid that is encoded by the
codon
Nonsense Mutation
 A point mutation in the DNA that results
in the change of a single amino acid to a
stop codon
Reading Frame
Sequence of DNA or RNA that is split
into groups of three nucleotides
(codons), initiated by the start codon
AUG
5’ cap
A modified Guanine that is added to the
first nucleotide of pre-MRNA to prevent
exonuclease degradation of the mRNA
sequence in Eukaryotes
3’ poly-A tail
 A tail of 150 or more Adenine
nucleotides that prevent exonuclease
degradation of the mRNA sequence in
Eukaryotes
What are the protective molecules in
Prokaryotes that prevent
exonuclease degradation of the
mRNA sequence
There are none