Professional Documents
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MaDhusuDhan reDDy
IntroDuctIon
• Odontoblast layer
• Cell-free zone
• Cell-rich zone
• Pulp proper
Dentin
Odontoblasts layer
Predentin
Cell rich zone
Pulp core
Dentin
cell Free zone
• It is also called weil’s zone
• 40 microns wide &relatively free of cells
• Traversed by
– 1. Blood vessels
– 2. Unmyelinated nerves
– 3. Cytoplasmic process of fibroblasts
• This zone is found below the odontoblastic zone
cell rIch zone
• Present in subodontoblastic layer
• Contains more proportions of fibroblast and
undifferentiated mesenchymol cells.
• Macrophages, dendritic cells and lymophocytes.
• Zone formed due to migration of cells from pulp
proper
• Mitosis seen when dead odontoblasts are replaced
• Also contain young collagen fibres during early
dentiogenis.
pulp core
• Odontoblasts
• Fibroblasts
• Undifferentiated Cells
• Defense Cells
ODONTOBLASTS
desmosome
ODONTOGENiC PROCESS
• Odontoblasts give off a single process that extends
into dentin and housed within dentinal tubules
• These process devoid of major organelles
• They contain abundance of microtubular
filaments and coated vesicles
FUNCTiONS OF ODONTOBLASTS
H&E stain
Immunohistoc
hemical
method
These cells have a dual function: synthesize and
degradation of fibers and ground substances in the same
cell .
• In young pulp:
• large cells with large multiple processes centrally located
oval nucleus, numerous mitochondria, well developed
golgi bodies well developed RER
Fibroblast
(protein secreting cell).
In periods of less activity and aging these cells
appear smaller and round or spindle-shaped with
few organelles , they are termed fibrocytes.
UNDiFFERENTiATED mESENCHYmE
• These mesenchymal cells are distributed through out the
pulp, frequently around the perivascular area - believed
to be toti potent cell
• They are Polyhedral shaped with peripheral processes
and large oval nuclei
• Difficult to differentiate from fibroblast under light
microscopy
• Under adequate stimilus they may differentiate into
odontoblast or fibroblast or macrophages.
• In older pulp, their number and ability to differentiate
comes down
DEFENCE CELLS
localized
diffuse
(pulp stones )
Dentinal
Tubules
Predentin
A, True pulp stone; B, Pulp
cavity; C, Dentin
A, False pulp stone; B, Pulp cavity
False pulp stone
Functions
Functions of
of the
the pulp
pulp
1- Inductive:
Dental papilla induces the enamel organ
formation and also determines the
morphology of the tooth .
2- Formative :
Pulp organ produces dentin. Odontoblasts
develop the organic matrix and function in its
calcification.
3-Reparative: through the formation of highly
mineralized reparative dentin at the site of
injury to seal off the pulp from the source of
irritation . Also the pulp may mineralize the
affected dentinal tubules by forming
sclerotic dentin .
4-Defensive : pulp inflammation represents
other aspect of its response to irritation. In
this condition, the defensive cells of the
pulp
will be increased and activated to repair
and heal the inflamed pulp and
phagocytoses the invading bacteria and
their toxin .
5- Protective: : any environmental irritating
stimuli always elicit pain as a response .
6- Nutritive : the extensive pulp vasculature
ensures an excellent nourishment to the
odontoblasts for the continuously forming
secondary dentin . This is provided through the
capillaries found in the odontogenic zone .