Professional Documents
Culture Documents
January 2020
INTRODUCTION
The charts included within this report are organised by BNF classification (legacy)
and show comparative costs at the NHS Basic price1,2 (as of January 2020) for
selected agents. Except where indicated otherwise, each chart shows the cost of 1
year3 of treatment at a commonly prescribed daily dose (shown in brackets). The
doses given are not intended to imply therapeutic equivalence and for some BNF
sub-classifications, such as angiotensin converting enzyme inhibitors (ACE
inhibitors), the doses may vary according to indication. Additionally, in some
therapeutic areas, for instance antibacterial drugs, the duration of treatment may
differ from that shown. Primarily, this report focuses on costs related to prescribing in
Adults. There are however a few exceptions where products specifically for use in
children are represented, such as in the Emollients and Infant formulas sections.
Additional notes to highlight any relevant cost related information are also added
where appropriate, to improve the clarity of the information presented.
Rationale for inclusion: The cost comparison charts (CCCs) aim to represent the
diversity of products available; including the least expensive, most prescribed, higher
cost products being prescribed and products with additional features. The products
included are furthermore considered in the context of National and local guidance
and stakeholder formulary decisions. It is not possible to represent all
pharmaceuticals within these charts.
1
NHS Business Services Authority (NHS BSA). Drug tariff. https://www.nhsbsa.nhs.uk/pharmacies-
gp-practices-and-appliance-contractors/drug-tariff
2
NHS BSA. Dictionary of medicines and devices (dM+d) https://www.nhsbsa.nhs.uk/pharmacies-gp-
practices-and-appliance-contractors/dictionary-medicines-and-devices-dmd
3
1 year in this instance is equal to 364 days (rather than 365) standardising 1 month as equal to 28
days.
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
1 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
Stakeholders (under password protection) can access the current version of the
CCCs via our website in three formats: PDF, Word and Excel. The Excel version
incorporates a more detailed comparison of contraceptives and allows charts to be
split by BNF subsections in some instances. The PDF format of the previous CCC
report is available for free access.
To navigate to the chart required, hover the cursor over the section required, press CTRL
and click with the left mouse button.
Contents by BNF Legacy / ePACT2 classification Page
1.1 Dyspepsia and gastro-oesophageal reflux disease ................................................................ 6
1.2 Antispasmodics and other drugs altering gut motility ............................................................. 6
1.3 Antisecretory drugs and mucosal protectants ........................................................................ 7
1.5.1 Aminosalicylates .................................................................................................................. 8
1.5.2 Corticosteroids: rectal foams ............................................................................................... 9
1.6 Laxatives ............................................................................................................................... 10
2.2 Diuretics ................................................................................................................................ 11
2.4 Beta-adrenoceptor blocking drugs ........................................................................................ 12
2.5.4 Alpha-adrenoceptor blocking drugs ................................................................................... 13
2.5.5 Drugs affecting the renin-angiotensin system ................................................................... 14
2.6.1/2.6.3 Nitrates and other antianginal drugs ......................................................................... 15
2.6.2 Calcium-channel blockers .................................................................................................. 16
2.8.1/2.8.2 Parenteral anticoagulants/oral anticoagulants.......................................................... 17
2.9 Antiplatelet drugs .................................................................................................................. 18
2.12 Lipid-regulating drugs ......................................................................................................... 19
3.1 Bronchodilators ..................................................................................................................... 20
3.2 Corticosteroids (respiratory): (i) corticosteroid inhalation devices ........................................ 21
3.2 Corticosteroids (respiratory): (ii) combination with bronchodilators, inhalation devices ....... 22
3.1 & 3.2 Inhaled therapy licensed for COPD ............................................................................. 23
3.3 Cromoglicate & related therapy, leukotriene receptor antagonists, and phosphodiesterase
type-4 inhibitors ........................................................................................................................... 24
3.4.1 Antihistamines.................................................................................................................... 24
4.1.1/4.1.2 Hypnotics/Anxiolytics ................................................................................................ 25
4.2.1/4.2.3 Antipsychotic drugs and drugs used for mania and hypomania: maintenance doses
(adults with psychosis) ................................................................................................................ 26
4.2.1 Antipsychotic drugs: low dose ........................................................................................... 27
4.3 Antidepressant drugs ............................................................................................................ 28
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder: (i) stimulant ..... 29
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder: (ii) stimulant;
methylphenidate modified release preparations only ................................................................. 30
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder: (iii) non-stimulant31
4.6 Drugs used in nausea and vertigo ........................................................................................ 31
4.7 Analgesics ............................................................................................................................. 32
4.7.2 Opioid analgesics: (i) oral preparations ............................................................................. 33
4.7.2 Opioid analgesics: (ii) transdermal patches ....................................................................... 34
4.7.2 Opioid analgesics: (iii) modified release preparations ....................................................... 35
4.7.2 Opioid analgesics: (iv) subcutaneous infusion; strong opioids .......................................... 36
£0 £20 £40 £60 £80 £100 £120 £140 £160 £180 £200
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Dicycloverine
(10mg TDS) £2,448.48
Propantheline
(15mg TDS and 30mg ON) £337.03
Hyoscine butylbromide
(20mg QDS) £156.00
Mebeverine MR
(200mg BD) £111.87
*Licensed for up to 3
*Peppermint oil capsules E/C:
£91.52 months. Cost reported is
Mintec® (1 TDS)
based on 1 year supply
Mebeverine for cost-comparison
(135mg TDS) £52.63 purposes only.
Contents
Famotidine
(40mg OD) £506.87
Misoprostol
(200mcg QDS) £243.39
Cimetidine
(400mg BD) £193.04
Nizatidine
(300mg OD) £187.22
Losec® MUPS
(20mg OD) £180.96
Omeprazole tablets
(20mg OD) £87.36
Nizatidine
(150mg OD) £54.36
Pantoprazole
(40mg OD) £46.80
Esomeprazole
(20mg OD) £32.89
Rabeprazole
(20mg OD) £21.32
Ranitidine
(150mg BD) £18.81
Lansoprazole capsules
(30mg OD) £15.73
Omeprazole capsules
(10mg or 20mg OD) £13.39
Lansoprazole capsules
(15mg OD) £12.22
1.5.1 Aminosalicylates
January 2020: Aminosalicylates: treatment doses - cost of 28 days treatment
Olsalazine capsules
(3g max single dose 1g) £432.00
Mezavant® XL tablets
(4.8g once daily) £80.17
Pentasa® tablets/granules
(4g daily in 2-3 divided doses) £68.86
Colazide® capsules
(2.25g three time daily) £58.97
Salofalk® tablets
(3g daily in 3 divided doses) £54.40
Salofalk® granules
(3g once daily) £45.59
£0 £50 £100 £150 £200 £250 £300 £350 £400 £450 £500
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Olsalazine capsules
(500mg twice daily) £1,872.00
Mezavant® XL tablets
(2.4g once daily) £521.13
Pentasa® tablets/granules
(2g once daily) £447.60
Salofalk® tablets
(1.5g daily in 3 divided doses) £353.59
Colazide® capsules
(1.5g twice daily) £340.70
Salofalk® granules
(1.5 daily in 3 divided doses) £313.84
£0 £200 £400 £600 £800 £1,000 £1,200 £1,400 £1,600 £1,800 £2,000
Contents
Prednisolone 20mg/application
£187.00
foam enema
£0 £20 £40 £60 £80 £100 £120 £140 £160 £180 £200
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
1.6 Laxatives
Manevac® (8 g) £2.66
Methylcellulose (2 g) £1.61
2.2 Diuretics
Chlortalidone
(50mg OD) £1,068.22
Amiloride
(5mg OD) £155.22
Eplerenone
£81.64
(50mg OD)
Torasemide
(5mg OD) £71.89
Spironolactone
(50mg OD) £62.53
Indapamide MR
(1.5mg OD) £41.25
Indapamide
(2.5mg OD) £30.68
Bumetanide
(1mg OD) £27.04
Spironolactone
(25mg OD) £15.99
Furosemide
(40mg OD) £10.66
Bendroflumethiazide
(2.5mg OD) £9.75
Timolol
(10mg BD) £968.00
Acebutolol
(400mg BD) £484.12
Metoprolol
(50mg TDS) £169.65
Nadolol
(160mg OD) £156.00
Nebivolol
(2.5mg OD) £153.14
Labetalol
(200mg BD) £127.66
Celiprolol
(200mg OD) £72.41
Sotalol
(80mg BD) £36.92
Carvedilol
(25mg OD) £31.33
Bisoprolol
(5mg OD) £11.05
Atenolol
(50mg OD) £9.49
*Doxazosin MR
(4mg OD) £65.00
Terazosin
(5mg OD) £32.63
Doxazosin
(4mg OD) £15.34
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
Dilzem XL®
(180 mg) £150.15
Adizem XL®
(180 mg) £134.81
Nicardipine
(30 mg BD) £123.89
Verapamil
(120 mg BD) £115.18
Nifedipine MR tabs
(20 mg BD) £114.53
Adizem SR®
(90 mg BD) £110.50
Viazem XL®
(180 mg) £95.68
Tildiem Retard®
(90 mg BD) £94.51
Zemret XL®
(180mg) £91.00
Nifedipine MR tablets
(30 mg) £89.05
Zemtard XL®
(180 mg) £80.60
Nifedipine MR capsules
(20 mg BD) £65.64
Felodipine MR
(5 mg) £54.73
Lercanidipine
(10 mg) £31.20
Lacidipine
(4 mg) £28.34
Amlodipine
(5 mg) £10.79
Ticagrelor
(90mg BD) £709.80
Prasugrel
(5mg OD) £313.04
Aspirin
25mg/Dipyridamole £163.80
MR 200mg BD
Dipyridamole MR
(200mg BD) £159.55
Prasugrel
(10mg OD) £85.67
Clopidogrel
(75mg OD) £19.37
Aspirin EC
(75mg OD) £10.92
Aspirin Dispersible
(75mg OD) £10.01
Contents
3.1 Bronchodilators
January 2020: Bronchodilators - cost of 1 year's treatment
Salmeterol Accuhaler® DPI
£426.00
(50 mcg BD)
Tiotropium Handihaler® refill DPI
£406.47
(18 mcg OD)
Indacaterol/glycopyrronium Breezhaler® DPI
£394.33
(85mcg/43mcg, 1 act OD)
Vilanterol/Umeclidinium Ellipta® DPI
£394.33
(22mcg/55mcg, 1 act OD)
Aclidinium Genuair® DPI
£394.33
(322 mcg, 1 act BD)
Aclidinium/formoterol Genuair® DPI
£394.33
(340mcg/12mcg, 1 act BD)
Olodaterol/tiotropium Respimat® SMI
£394.33
(2.5mcg/2.5mcg, 2 act OD)
Indacaterol inhalation powder caps DPI
£390.57
(150 mcg, 1 act)
Salmeterol inhaler MDI
£355.02
(25 mcg, 2 act BD)
Umeclidinium Ellipta® DPI
£333.67
(65mcg, 1 act OD)
Glycopyrronium Breezhaler® DPI
£333.67
(50mcg, 1 act)
Olodaterol Respimat® SMI
£319.71
(2.5mcg, 2act OD)
Tiotropium Braltus Zonda® DPI
£313.04
(10 mcg OD)
Formoterol Turbohaler® DPI
£300.91
(6 mcg BD)
Tiotropium Respimat® SMI
£279.07
(5 mcg OD)
Soltel® (Salmeterol) inhaler MDI
£242.06
(25 mcg, 2 act BD)
Formoterol Easyhaler®
£144.08
(12 mcg, 1 act BD)
Terbutaline Turbohaler® DPI
£100.71
(500 mcg, 1 act QDS)
Salamol Easi-Breathe® MDI
£91.73
(100 mcg, 2 act QDS)
Airomir Autohaler® MDI
£87.65
(100 mcg, 2 act QDS)
Salbutamol Accuhaler® DPI
£87.36
(200 mcg, 1 act QDS)
Ipratropium inhaler MDI
£80.95
(20 mcg, 2 act QDS)
Salbutamol Easyhaler® DPI
£48.27
(200 mcg, 1 act QDS)
Salbutamol Easyhaler® DPI
£48.19
(100mg, 2 act QDS)
Airomir® inhaler MDI
£28.68
(100 mcg, 2 act QDS)
Salbutamol inhaler CFC-free MDI
£21.84
(100 mcg, 2 act QDS)
Ventolin Evohaler® MDI
£21.84
(100 mcg, 2 act QDS)
£0 £50 £10 0 £15 0 £20 0 £25 0 £30 0 £35 0 £40 0 £45 0
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
Roflumilast
(500mcg OD) £457.55
Montelukast
(10mg OD) £53.04
3.4.1 Antihistamines
January 2020: Antihistamines - cost of 1 year's treatment
Contents
4.1.1/4.1.2 Hypnotics/Anxiolytics
January 2020: Hypnotics and anxiolytics - cost of 14 days treatment
Loprazolam 1 mg £11.25
Lormetazepam 1 mg £8.27
Melatonin MR 2 mg £7.18
Zolpidem 10 mg £0.96
Temazepam 20 mg £0.78
Nitrazepam 5 mg £0.52
Diazepam 10 mg £0.51
Contents
4.2.1/4.2.3 Antipsychotic drugs and drugs used for mania and hypomania:
maintenance doses (adults with psychosis)
January 2020: Drugs used for adults with psychosis:
maintenance doses - cost of 1 year's treatment
Risperidone 500microgram
(orodispersible) BD £475.28
Contents
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder:
(i) stimulant
Dexamfetamine tabs
(Generic, 5mg BD) £49.42
Dexamfetamine tabs
(Generic, 2.5mg BD) £24.71
Dexamfetamine tabs
(Amfexa®, 5mg QDS) £74.26
Dexamfetamine tabs
(Amfexa®, 5mg BD) £37.13
Dexamfetamine tabs
(Amfexa®, 2.5mg BD) £18.56
Lisdexamfetamine caps
(70mg OD) £83.16
Lisdexamfetamine caps
(50mg OD) £68.60
Lisdexamfetamine caps
(30mg OD) £58.24
Methylphenidate
(20mg BD) £20.38
Methylphenidate
(10mg BD) £7.28
Methylphenidate
(5mg BD) £5.66
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder:
(ii) stimulant; methylphenidate modified release preparations only
4.4 CNS stimulants and drugs used for attention deficit hyperactivity disorder:
(iii) non-stimulant
January 2020: Drugs used for attention deficit hyperactivity disorder - Non-stimulant -
cost of 28 days treatment
Atomoxetine 4mg/ml oral
solution sugar free (100mg OD) £198.33
Atomoxetine caps
(80mg-100mg OD) £67.33
Atomoxetine caps
(10mg, 18mg or 60mg OD) £50.56
Atomoxetine caps
(25mg or 40mg OD) £49.76
Guanfacine MR tabs
(Intuniv®) 7mg (4mg + 3mg) OD £141.68
Guanfacine MR tabs
(Intuniv®, 6mg OD) £131.04
Guanfacine MR tabs
(Intuniv®) 5mg (3mg + 2mg) OD £124.04
Guanfacine MR tabs
(Intuniv®, 4mg OD) £76.16
Guanfacine MR tabs
(Intuniv®, 3mg OD) £65.52
Guanfacine MR tabs
(Intuniv®, 2mg OD) £58.52
Guanfacine MR tabs
(Intuniv®, 1mg OD) £56.00
£0 £50 £100 £150 £200 £250
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
4.6 Drugs used in nausea and vertigo
January 2020: Drugs used in nausea and vertigo - cost of 1 year's treatment
Hyoscine patch
(1mg/72hours, once every 3 days) £777.66
Hyoscine
(20 mg TDS) £117.00
Promethazine
(Avomine®, 25 mg BD) £81.38
Cinnarizine
(15 mg TDS) £65.13
Promethazine
(Phenergan® 25 mg BD) £64.74
Cyclizine
(50 mg BD) £51.98
Prochlorperazine
(5 mg TDS) £41.34
Metoclopramide
(10 mg TDS) £38.61
Betahistine
(16 mg BD) £37.79
Contents
4.7 Analgesics
January 2020: Analgesics - cost of 7 days treatment
Tramacet®
(8 tablets) £9.03
Tramacet® effervescent
(8 tablets) £9.03
Aspirin 300 mg
(12 tablets) £8.98
Tramadol MR 400 mg
(1 tablet) £7.13
Remedeine®
(8 tablets) £6.41
Nefopam 30 mg
(9 tablets) £3.96
Co-codamol 30/500
(8 capsules) £3.08
Co-codamol 30/500
(8 tablets) £2.58
Codeine 30 mg
(8 tablets) £2.42
Dihydrocodeine 30 mg
(8 tablets) £2.38
Co-dydramol 10/500
(8 tablets) £1.78
Co-codamol 8/500
(8 tablets) £1.78
*see NHSE and NHSI (2019).
Tramadol 50 mg Items which should not routinely be
(8 capsules) £1.53
prescribed in primary care:
Paracetamol 500 mg Guidance for CCGs. Select the link
(8 tablets) £1.33 beneath the chart.
£0 £2 £4 £6 £8 £10
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
Pethidine 50 mg
£55.91
(8 tablets)
Pentazocine 25 mg tablets
£50.08
(8 daily)
Pentazocine 50 mg capsules
(4 daily) £28.50
Oxycodone 40 mg MR tablets
(2 daily) £25.05
Oxycodone 20 mg capsules
£22.86
(4 daily)
Tapentadol 75 mg tablets
(4 daily) £18.68
Hydromorphone 8 mg MR capsules
(2 daily) £14.02
Meptazinol 200 mg
(8 tablets) £11.06
Tramadol MR 400 mg
(1 tablet) £7.13
Morphine 20 mg
(5 tablets) £6.63
Morphine MR tablets
(60 mg BD) £5.67
*see NHSE and NHSI (2019).
Items which should not routinely
Buprenorphine 400 mcg sublingual be prescribed in primary care:
(4 tablets) £5.64
Guidance for CCGs. Select the
Morphine MR capsules link beneath the chart.
(60 mg BD) £3.78
Osmanil® £23.46
Victanyl® £22.55
Durogesic DTrans®,
Fentanyl and Yemex® £15.69
Fentanyl patches -
Fencino® £10.55 50mcg per hour, 1
every 3 days
Matrifen® and
Mezolar Matrix® £9.38
Opiodur® £8.91
Hapoctasin®
(1 every 3 days) £8.29
Bupeaze®
(1 every 4 days) £6.12
Butrans® £7.89
Butec®, Reletrans®
and Sevodyne® £3.55
Buprenorphine once weekly
patches - 10 mcg per hour
Panitaz® and Bupramyl® £3.16
Bunov® £2.49
Contents
MXL 120mg
capsules (1 OD) £7.29
MST Continus 60mg
tablets (1 BD) £5.67
Morphgesic SR 60mg
tablets (1 BD) £4.21
Zomorph 60mg modified-release
capsules (1 BD) £3.78
MXL 60mg
capsules (1 OD) £3.74
MST Continus 30mg tablets (1 BD) £2.91 Several NHS bodies recommend
that modified-release forms of strong
Morphgesic SR 30mg opioids be prescribed by brand
tablets (1 BD) £2.16 name to avoid confusion and reduce
risk of harm.
Zomorph 30mg modified-release
capsules (1 BD) £1.94
Diamorphine 15mg/24hours £5.70 Please Note: Doses shown are only approximately equivalent and for
price comparison purposes only. Extreme caution is required when
Morphine 30mg/24hours £3.45 converting from one parenteral opioid to another and specialist advice
Oxycodone 15mg/24hours £3.20 should always be sought.
Contents
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
Contents
4.8 Antiepileptic drugs
January 2020: Antiepileptic drugs - cost of 1 year's treatment
Ethosuximide 250mg capsules (QDS) £4,498.00
Perampanel 2mg tablets (OD) £1,820.00
Lacosamide 150mg (BD) £1,686.62
Brivaracetam (Briviact®) 50mg tablets (BD) £1,685.32
Eslicarbazepine 800mg £1,650.13
Primidone 250mg tablets (BD) £831.38
Levetiracetam (Desitrend®) 750mg sachets (BD) £750.69
Vigabatrin 500mg tablets (QDS) £646.61
Topiramate 200mg tablets (BD) £542.00
Epival CR tablets (1200mg daily) £254.36
Epilim Chrono tablets (1200mg daily) £254.25
Clonazepam 2mg tablets (BD) £246.21
Oxcarbazepine 450mg tablets £226.12
Sodium valproate 200mg gastro-resistant tablets £211.19
Episenta MR capsules (1200mg daily) £189.28
Phenytoin sodium 100mg capsules (TD) £143.39
Zonisamide 100mg capsules (QDS) £120.38
Clobazam 10mg tablets (BD) £92.70
Levetiracetam 750mg tablets (BD) £76.93 Levetiracetam (Desitrend®) 750mg sachets (BD) = Levetiracetam (Desitrend®) 500mg sachets (BD) +
Levetiracetam (Desitrend®) 250mg sachets (BD)
Carbamazepine 400mg MR tablets (BD) £65.26
Lamotrigine 100mg tablets (BD) £56.68 Oxcarbazepine 450mg tablets = Oxcarbazepine 300mg tablets (BD) + Oxcarbazepine 150mg (BD) tablets
Modified-release sodium valproate:
Gabapentin 400mg capsules (TD) £42.81 Epilim Chrono tablets 1200mg daily = Epilim Chrono 500mg tablets (BD) + Epilim Chrono 200mg tablet (OD)
Pregabalin 150mg capsules (BD) £40.17 Episenta MR capsules 1200mg daily = 2 x Episenta 300mg MR capsules BD
Epival CR tablets 1200mg daily = 2 x Epival 300mg CR tablets BD
Phenobarbital 30mg tablets (TD) £37.44
£0 £500 £1,000 £1,500 £2,000 £2,500 £3,000 £3,500 £4,000 £4,500 £5,000
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
Pramipexole tablets
£45.33
(1050mcg [700mcg + 350mcg], TDS)
Pramipexole tablets
£6.41
(700mcg, TDS)
Pramipexole tablets
£38.92
(350mcg, TDS)
Pramipexole tablets
£11.98
(88mcg, TDS)
Ropinirole MR tablets
£126.33
(24mg, OD)
Ropinirole MR tablets
£84.22
(16mg, OD)
Ropinirole MR tablets
£42.11
(8mg, OD)
Ropinirole MR tablets
£25.09
(4mg, OD)
Ropinirole MR tablets
£12.54
(2mg, OD)
Ropinirole tablets
£323.72
(6mg [5mg + 1mg], QDS)
Ropinirole tablets
£247.51
(5mg, QDS)
Ropinirole tablets
£185.63
(5mg, TDS)
Ropinirole tablets
£36.78
(2mg, TDS)
Ropinirole tablets
£57.16
(1mg, TDS)
£0 £50 £100 £150 £200 £250 £300 £350
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
Doses given do not imply therapeutic equivalence £0 £10 £20 £30 £40 £50
copyright © RDTC 2020
Contents
Galantamine 24mg
MR capsules £1,037.40
Galantamine 12mg
tablets £963.30
Rivastigmine 4.6mg/24
hours patches £946.04
Memantine hydrochloride
5 mg/actuation oral solution £897.04
Galantamine 16mg
MR capsules £843.70
Rivastigmine 6mg
capsules £836.94
Galantamine 8mg
tablets £805.61
Rivastigmine 9.5mg/24
hours patches £242.30
Rivastigmine 3mg
capsules £72.80
Memantine 20mg
tablets £25.48
Donepezil 10mg
tablets £14.95
Donepezil 5mg
tablets £12.87
Contents
£0 £1 £2 £3 £4 £5 £6 £7 £8
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
250mg/5ml
£16.14
Flucloxacillin oral solution:
250mg QDS (7 days)
250mg caps: £1.67
250mg/5ml
Erythromycin suspension: £8.77
250mg QDS (5 days)
250mg tabs: £1.21
250mg/62mg/5ml
Co-Amoxiclav suspension: £5.00
TDS (5 days) 250mg/125mg
tabs: £1.56
50mg/5ml
Trimethoprim suspension: £4.99
100mg BD (3 days)
100mg tabs: £0.19
250mg/5ml
Clarithromycin suspension: £4.84
250mg BD (5 days)
250mg tabs: £1.04
250mg/5ml
Penicillin V oral solution: £4.78
250mg QDS (5 days)
250mg tabs: £0.81
250mg/5ml
suspension: £3.84
Amoxicillin 250mg caps: £1.86
500mg TDS (5 days)
500mg caps: £1.05
Contents
5.1.1 Penicillins
January 2020: Penicillins - cost of 5 days treatment
Ampicillin (1 g) £14.39
Flucloxacillin (1 g) £0.96
Phenoxymethylpenicillin / Penicillin
V (1 g) £0.81
Contents
5.1.2 Cephalosporins
January 2020: Cephalosporins - cost of 5 days treatment
Contents
5.1.3 Tetracyclines
January 2020: Tetracyclines - cost of 5 days treatment
*Tetracycline (1 g) £1.88
*Oxytetracycline (1 g) £1.36
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
5.1.12 Quinolones
January 2020: Quinolones - cost of 5 days treatment
Contents
£0 £1 £2 £3 £4 £5 £6
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
Contents
Contents
Hypodermic equipment: (i) needles for PF and reusable insulin pens (4mm to 6
mm)4
January 2020: Needles for Pre-filled and Reusable Insulin Pens
4mm to 6mm - cost of 100 needles [Blue signifies safety needles]
Registered trade names ®
BD AutoShield Duo £30.41
Microdot Dual Safety £25.00
Dropsafe Safety £23.00
Mylife Clickfine AutoProtect £19.00
Microdot Safety £17.00
Neon Verifine Safety £14.89
NovoFine £13.02
NovoTwist £12.99
GlucoRx Safety £12.95
Microdot Max Safety £12.89
Insupen 33G £12.69
Unifine Pentips 33G + Unifine
Pentips Plus £12.50
Unifine Pentips 5mm/31G £12.00
Unifine Pentips 31G & 32G £11.75
IME-FINE £11.20
BD Micro-Fine Ultra
& BD Micro-Fine+ £9.80
Mylife Clickfine £9.11 NHS Clinical Commissioners and NHS
England guidance recommends that
Nanopass £7.60 prescribers in primary care should not
NeedleBay Fine
initiate insulin needles that cost more than
£6.95
£5 per 100 needles for any diabetes
Omnican Fine 31G £6.01 patient. For further details, select the link
Glucoject, Insupen & Unifine beneath the chart
Pentips Plus £5.95
HaemoFine £5.35
Microdot Droplet £4.95
GlucoRx FinePoint and Neon BD Viva pen needles
Verifine £4.50
supplied in packs of
BD Viva £3.99 90 costing £3.59
TriCare, 4SURE 31G & 32G
+ Omnican Fine 32G £3.95
PROFine £3.80
Mylife Penfine Classic £3.55
GlucoRx CarePoint
and CareFine £2.75
Microdot Max £2.74
Needles may not be interchangeable - consult product literature copyright © RDTC 2020
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
4
NHS BSA Drug tariff, Part IXA: Appliances
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
48 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
Hypodermic equipment: (ii) needles for PF and reusable insulin pens (8 mm)4
January 2020: Needles for Pre-filled and Reusable Insulin Pens 8mm -
cost of 100 needles [Blue signifies safety needles]
Registered trade names ®
NovoFine £9.24
IME-FINE £8.20
BD Micro-Fine+ £7.99
Nanopass £7.60
NHS Clinical Commissioners and NHS
NeedleBay Fine £6.95 England guidance recommends that
prescribers in primary care should not
Omnican Fine £6.01 initiate insulin needles that cost more than
£5 per 100 needles for any diabetes
Glucoject, Insupen & Unifine patient. For further details, select the link
Pentips Plus £5.95
beneath the chart
HaemoFine £5.35
PROFine £3.80
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
4
NHS BSA Drug tariff, Part IXA: Appliances
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
49 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
Softclix lancets
0.4mm/28gauge £4.03
FreeStyle lancets
0.5mm/28gauge £3.82
Microlet lancets
0.5mm/28gauge £3.72
Greenlan lancets
0.35mm/28gauge £3.00
CareSens lancets
0.36mm/28gauge £2.95
FastClix lancets
0.3mm/30gauge £2.89
Palmdoc Lancets
0.38mm/30gauge £2.85
Mylife lancets
0.3mm/30gauge £2.75
GlucoZen lancets
0.36mm/28gauge £2.50
GlucoRx lancets
0.31mm/30gauge £2.25
Droplet lancets
0.31mm/30gauge £2.19
£0 £1 £2 £3 £4 £5 £6 £7
copyright © RDTC 2020
Contents
4
NHS BSA Drug tariff, Part IXA: Appliances
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
50 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
6.1.6 Blood glucose monitoring: (i) test strips (50) greater than £10
January 2020: Blood glucose monitoring - cost of 50 tests more
than £10
Registered trade names ®
FreeStyle Lite £16.41
FreeStyle £16.40
Sensocard £16.30
Myglucohealth £15.50
Breeze 2 £15.00
Betachek C50
Betachek C50 £14.99 testing strips
w hen supplied in
Dario packs of 100
£14.95 costing £29.98
BGStar £14.73
Betachek G5 £14.19
IME-DC £14.10
CareSens N £12.75
MediTouch 2 £12.49
Active £10.03
Contents
6.1.6 Blood glucose monitoring: (ii) test strips (50) less than £10
January 2020: Blood glucose monitoring - cost of 50 tests below
£10
Registered trade names ®
Contour, Mobile and
OneTouch Select Plus £9.99
GlucoMen areo Sensor and
Advocate Redi-Code+ £9.99
Dario Lite and
CareSens PRO £9.95
GlucoRx GO and
GO Professional £9.95
TRUEyou £9.92
OKmeter Core £9.90
Omnitest 3 and 5 £9.89
Element, GlucoLab
and GluNEO £9.89
palmdoc iCare Advanced £9.70
Contour TS £9.60
Mylife Pura and Unio £9.50
Microdot + £9.49
Fora Advanced pro GD40 £9.25
AutoSense testing
AutoSense £9.00 strips w hen
supplied in packs
VivaChek Ino and 4SURE £8.99 of 25 costing £4.50
GlucoRx HCT Glucose
and Nexus £8.95
WaveSense JAZZ
and JAZZ Duo £8.74
Contour Plus £8.50
SURESIGN Resure £8.49
TEE2 £7.75
Performa £7.50
Microdot Max £7.49
SD Codefree and
*Kinetik Wellbeing £6.99
Betachek Visual £6.80
Visually
readable
Glucoflex-R £6.75
*True Metrix £6.25
Finetest Lite £5.95
*The follow ing products are based on
palmdoc £5.90 w hen they are supplied in packs of
100 costing:
GlucoRx Q £5.45 *GlucoZen.auto - £10.85
Kinetik Wellbeing - £13.98
*GlucoZen.auto £5.43 *True Metrix -£12.50
£0 £2 £4 £6 £8 £10 £12
Test strips are not usually interchangeable - consult manufacturers' literature copyright © RDTC 2020
Contents
Contents
6.4.1 Female sex hormones and their modulators: (i) combination HRT
preparations
January 2020: Combination HRT preparations - cost of 28 days
treatment
Duavive® (Conjugated
oestrogens/bazedoxifene) £15.00
6.4.1 Female sex hormones and their modulators: (ii) oestrogen only HRT
patches
January 2020: Oestrogen only HRT patches - cost of 28 days
treatment
£0 £1 £2 £3 £4 £5 £6 £7 £8
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
6.4.1 Female sex hormones and their modulators: (iii) oestrogen only HRT
preparations except patches
January 2020: Oestrogen only HRT preparations (excluding
patches) - cost of 28 days treatment
Vaginal ring
£0 £2 £4 £6 £8 £10 £12
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Contents
Contents
Oral Progestogen-only
Zelleta (28) £12.91 Contraceptives
Contents
Items which should not routinely be prescribed in primary care: Guidance for CCGs
8.3.4.2 Gonadorelin analogues: prostate cancer indication
January 2020: Prostate cancer treatments - cost of 1 year's treatment
Contents
Contents
Contents
Nabumetone (1 g) £89.70
£0 £50 £100 £150 £200 £250 £300 £350 £400 £450 £500
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Catacrom®
(Sodium cromoglicate 2% 0.3ml unit dose) £19.32
Alomide®
(Lodoxamide 0.1%) 10ml £5.21 Assumptions & Calculations
A drop equates to 0.05ml. For example a 10ml bottle
Optrex Allergy® contains 200 drops/applications per pack for non-metered-
(Sodium cromoglicate 2%) 10ml £3.88
dose products
Opticrom Allergy® 1 drop/application per eye to both eyes for lodoxamide
(Sodium cromoglicate 2%) 10ml £3.35 and sodium cromoglicate four times daily. For all
antihistamines as above but twice daily.
Pollenase Allergy® Rounded up to nearest full pack
(Sodium cromoglicate 2%) 10ml £3.35
Relestat®
(Epinastine 500 mcg/ml) 5ml £9.90
Zaditen®
(Ketotifen 250 mcg/ml) 5ml £7.80
Ketofall®
(Ketotifen 0.4ml unit dose) £6.95
Optilast®
(Azelastine 0.05%) 8ml £6.40
Antihistamines
Opatanol®
(Olopatadine 1mg/ml) 5ml £4.68
Otrivine-Antistin®
(Antazoline 0.5%, Xylometazoline 0.05%) 10ml £3.35
Contents
Pilocarpine 4% £369.20
Pilocarpine 2% £296.27
Pilocarpine 1% £288.60
Travoprost £38.87
Brinzolamide £36.40
Dorzolamide 2% £31.46
Contents
13.2.1 Emollients: (iii) bath and shower preparations, cost per 100g or 100ml
January 2020: Emollients: bath and shower preparations (cost per
100g or 100ml)
Oilatum® shower gel fragrance free (150g) £3.51
Zerolatum® Emollient bath additive (500ml) £0.96 N.B. see NHSE and NHSI (2019).
Items which should not routinely be
Hydromol® Bath & Shower emollient (500ml) £0.89 prescribed in primary care:
Guidance for CCGs. Select the link
beneath the chart.
LPL 63.4 (500ml) £0.63
£0 £1 £2 £3 £4
Doses given do not imply therapeutic equivalence copyright © RDTC 2020
Items which should not routinely be prescribed in primary care: Guidance for CCGs
Contents
Contents
Dovobet® ointment
(60g)** £277.76
Conditions for which over the counter items should not routinely be prescribed in primary
care: Guidance for CCGs. (2018)
Contents
Contents
5
BNF for Children. Borderline substances.
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
76 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
Appeel® £9.73
Dansac £9.66
EasyLease £9.52
Brava® £9.33
Sensi-Care® £8.68
Independence £7.28
Adapt™ £7.21
Peel-Easy™ £7.18
Elite® £6.98
Salts £6.81
Remove £6.80
ZenSetiv £5.90
Lifteez £5.60
CliniPeel® £5.50
Clear £5.19
Offmate £5.10
Lift £3.28
£0 £2 £4 £6 £8 £10 £12
6
NHS BSA Drug tariff, Part IXC: Stoma appliances.
NOT TO BE USED FOR COMMERCIAL OR MARKETING PURPOSES
77 January 2020
Regional Drug and Therapeutics Centre Cost comparison charts
Expiry dates below take account of the SPC and any paediatric extension. The table
also indicates where a licence for a generic/biosimilar product is in the latter stages
of the EU licensing process or is already available in the EU. However, it does not
follow that a generic/biosimilar product will be available in the UK as patent issues
differ between countries. Patent legislation is complex and the information below
should be used as a guide only.
Note that patent expiries are subject to change when new licence extensions (SPC
or paediatric) are granted to the originator product or if court decisions alter the
patent status of a drug. In addition, the patent expiries detailed only cover the basic,
manufacturing patent. Additional patents on formulations and uses can influence
when a generic or biosimilar becomes available commercially.
Patent expiry date may not give an accurate date as to when a generic version will
actually be marketed in the UK, once a generic has been granted a product licence.
Generic
Patent expiry Date includes
or biosimilar Commissioning
Drug BNF date * = UK patent paediatric
available/ in route
only, no SPC extension
development
Melatonin (controlled
release - Circadin®) 4 2020 Jan - CCG
Asenapine 4 2020 Feb - CCG
Ziconotide 4 2020 Feb -- NHSE
Dexrazoxane 8 2020 Mar - NHSE
Erlotinib HCl 8 2020 Mar - Yes NHSE
Aliskiren 2 2020 Apr - CCG
Cinacalcet 9 2020 Apr Yes Yes NHSE
Eculizumab 9 2020 Apr - NHSE
Temsirolimus 8 2020 Apr - NHSE
Tipranavir 5 2020 May - NHSE
Bevacizumab 8 2020 Jun Yes Yes NHSE
C1-esterase inhibitor 3 2020 Jul - NHSE
Natalizumab 8 2020 Jul Yes NHSE
Tapentadol 4 2020 Jul - CCG
Fosaprepitant 4 2020 Aug Yes NHSE
Micafungin 5 2020 Sep - NHSE
Ambrisentan 2 2020 Oct - Yes NHSE
Depends on
Tocilizumab 10 2020 Dec Yes indication