Chemical Preparation, which contains one or more drugs, administered b.

A drug is exposed more prominent liver

with the intention of producing a therapeutic effect. metabolism
a. Mana c. A drug can be administered in a variety of
b. Drugs doses
c. Medicine d. A drug is exposed to gastric secretion
d. Food
In checking the right patient, all of these are correct, EXCEPT:
Proportion of a drug or other substance which enters the circulation when a. Birthdate
introduced into the body and so is able to have an active effect: b. Full name
a. Bioavailability c. Attending Physician
b. Therapeutic Window d. Medical records number
c. Biotransformation
d. Therapeutic Index While reading the doctor’s order, Nurse James is having difficulties
understanding the order. Which of the following should he perform to
Which of the ff statements is TRUE ensure that he prepares the right medications for his patients?
a. Medicines are taken in its purest form to illicit a. Ask the charge nurse regarding the
its pharmacologic effect questionable order
b. All medicines are drugs b. Ask the outgoing nurse regarding the
c. Drugs are taken in its purest form to illicit its questionable order
pharmacologic effect c. Ask the prescribing doctor regarding the
d. All drugs are medicine questionable order
d. Ask the patient regarding the questionable
The organ that primarily metabolizes drugs is order
a. Stomach
b. Kidney This has special coating that resists GI tract acids:
c. Pancreas a. Enteric-Coated tablets
d. Liver b. Suppositories
c. Lozenges
Which of the following is FALSE d. Capsules
a. Drugs are less likely to be absorbed in acidic pH
b. Liquid form are more rapidly available for While reading the doctor’s order, Nurse Clara is having difficulties
absorption understanding the order. Which of the following is NOT CORRECT?
c. Food in the GI tract may interfere with a. Ask the prescribing doctor regarding the
dissolution questionable order
d. Some drugs may be gastric irritant, so food b. Withhold the order and inform the charge
may be necessary to dilute drug concentration nurse regarding the questionable order
c. Withhold the order indefinitely
Which of the following is the study of drug concentration and its effects in d. Document all attempts to contact the
the body? prescribing doctor
a. Pharmaceutics
b. Pharmacokinetics In writing a phone order from a doctor, all of the following must be
c. Pharmacodynamics observed, EXCEPT:
d. Pharmacotherapeutics a. Use TALL Man lettering for sound-alike drugs
b. Read back the order to the ordering physician
He discovered Penicillin in 1928 for confirmation
a. Selman Waksman c. Avoid use of addbreviations
b. Felix Hoffman d. Use two zeroes after decimal points
c. Alexander Fleming
d. Jonas Salk Pick out the appropriate alimentary route of administration when passage
of drugs through liver is minimized:
This is the range where in the plasma concentration of shows its a. Rectal
therapeutic effect. b. Oral
a. Effective Dose c. Intraduodenal
b. Lethal Dose d. Transdermal
c. Therapeutic Index
d. Therapeutic Window Which route of drug administration is most likely to lead to the first-pass
effect?
Drug X when taken, will start to have a therapeutic effect after 2 hours of a. Sublingual
administration, will have its strongest effect after 4 hours of b. Intramuscular
administration, and will lose its effect after 6 hours of administration. If a c. Oral
patient takes Drug X at 6PM, when will the peak effect happen? d. Intravenous
a. 8 PM
b. 10 PM Which of the following measures is performed when administering IV
c. 2 AM medications that are irritating to the subcutaneous tissue?
d. 12 MN a. Z-tract technique
b. SQ Route administration
Epinephrine is an adrenergic agonist drug. Which of the following drug c. Air lock technique
action does it has? d. IM route administration
a. Stimulation of receptor to cause a
pharmacologic effect Among the patient identifiers below, which of them is the most essential:
b. Irritate cells to cause a pharmacologic effect a. Hospital number
c. Replacement of a neurotransmitter in the body b. Gender
d. Depression of a receptor to illicit a c. Patient's name
pharmacologic effect d. Birthdate
e. Age
Tick the feature of the sublingual route
a. Pretty fast absorption At the start of his shift, Nurse Liam noticed 3 Ibuprofen capsules in his
patient’s medication box. He checked the patient’s Medication
Administration Records and noticed the order: “Ibuprofen 200 mg 1 D. Central Nervous System
capsule every 6 hours for episode of headache.” The last dose of Ibuprofen
was given 5 days ago. What shall Liam do with the 3 Ibuprofen capsules?
a. Give the 3 capsules to the patient and instruct
his patient to take 1 capsule when headache Bronchodilation is an effect of which drug?
attacks A. timolol (Blocadren)
b. Return the 3 capsules to the pharmacy and B. A & C
order the capsules when the patient reports C. albuterol (Ventolin, Proventil)
episode of headache D. ipratropium (Atrovent)
c. Keep the 3 capsules in the patient’s medication
box to anticipate any episodes of headache
d. Surrender the 3 capsules to the charge nurse The use of atropine, and anticholinergic, for treatment of symptomatic

Parenteral administration bradycardia is contraindicated for a client with which of the following
a. Usually produces a more rapid response than
oral administration conditions?
b. Is too slow for emergency use A. Urinary incontinence
c. Generally results in a less accurate dosage than B. Right sided heart failure
oral administration C. Increased intracranial pressure
d. Cannot be used with unconsciousness patients D. Glaucoma

This are flat disc containing a medical agent in a suitable flavored base,
usually throat remedies
a. Lozenges Which of the following is an Alpha agonist that promotes vasoconstriction
b. Suppositories
and elevates blood pressure?
c. EC tablet
A. terbutaline (Brethine)
d. Capsules
B. ipratropium (Atrovent)
Which of the following is CORRECT? C. methoxamine (Vasoxyl)
D. metoprolol (Lopressor)
a. Suspensions must be shaken thoroughly prior
to administration
b. Sublingual medications can be swallowed
c. Enteric-coated tablets can be given via NGT by Pressor effects of epinephrine are blocked by this drug ("epinephrine
disintegrating them manually and mixing them
with water reversal")
d. Insulin syringes can be swap with tuberculin A. metoprolol (Lopressor)
syringes because both can carry a maximum of B. phentolamine (Regitine)
1mL of liquid C. propranolol (Inderal)
D. phenylephrine (Neo-Synephrine)
What is characteristic of the oral route?
a. Fast onset of effect
b. Absorption depends on GI tract secretion and
motor function Nurse Cara is caring for a client who is receiving a central-acting anti-
c. A drug reaches the blood passing the liver
d. The sterilization of medicinal forms is adrenergic agent, methyldopa hydrochloride (Aldomet), intravenously.
obligatory
Which of the following assessment findings would indicate to the nurse
Which of the following drug activates alpha receptors?
that the client may be having an adverse reaction to the medication?
A. Propranolol (Inderal)
A. Palpitations
B. Phenylephrine (Neo-Synephrine)
B. Mood changes
C. Terbutaline (Brethine)
C. Hyperkalemia
D. Isoproterenol (Isuprel)
D. Headache

Which of the following effects Epinephrine, a sympathomimetic agent,

A client is ordered an anticholinergic agent, atropine, to be administered
does to the heart?
preoperatively. Which physiological effect should the nurse monitor for?
A. increased heart rate
A. Reduce heart rate
B. decreased contractility B. Enhance sedation
C. Elevate blood pressure
C. coronary vasodilation D. Dry secretions

D. A&C

Beta 1 receptors are found on the:

Neurotransmitters are _____________ that travel across the A. Heart
B. Stomach
____________ to another cell. C. Lungs
A. chemicals; synapse D. Adipose Tissue
B. electrical signals; synapse
C. electrical signals; receptors
D. chemicals; receptors
Orthostatic (postural) hypotension is a common side-effect of:
The "fight or flight" response during threatening situations in the role of A. Beta Receptor Activation
the: B. Alpha Receptor Blocker
A. Sympathetic Nervous System C. Dopamine Receptor Blockade
B. Parasympathetic System D. Alpha Receptor Activation
C. Somatic Nervous System
 D. Streptokinase

These medications increase the myocardial contractility

Nurse Angelia is administering an adrenergic agent, albuterol (Proventil), A. Positive chronotropic
B. Negative inotropic
to a child with asthma. Which of the following assessments by the nurse
C. Positive inotropic
indicate the need for an adjustment of the medication? D. Negative dromotropic
A. Temperature of 39 degrees Celsius
B. Edema is the lower extremities This drug is useful in terminating atrial but not ventricular tachycardias
C. Lethargy and fatigue A. Flecainide
D. Apical Pulse of 112 B. Sotalol
C. Lidocaine
D. Verapamil

Nurse Hanna is preparing a teaching plan for a client with migraine Angina pectoris is
A. Result from insufficient blood supply to the
headaches who is receiving a beta blocker to help manage this disorder. myocardium due to stenosis or obstruction of coronary
arteries
What instructions would be appropriate to relay to this client? B. An often-fatal form of arrhythmia characterized by
A. “Take this drug as ordered, even when feeling well, to rapid, irregular fibrillar twitching of the ventricles of
prevent vascular changes associated with migraine the heart instead of normal contractions, resulting in a
headaches.” loss of pulse
B. “This medication will have no effect on your heart rate C. The cardiovascular condition in which the heart's ability
or blood pressure because you are taking it for to pump blood weakens
migraines.” D. All of the above
C. “This drug will relieve the pain during the aura phase
soon after a headache has started.” This drug increases the osmotic blood plasma and relieves increase in ICP
D. “Take this drug only when you have prodromal A. Furosemide
symptoms indicating the onset of a migraine B. Mannitol
headache.” C. Lasix
D. Hydrochlorothiazide
Drugs activating this receptor are used in treating asthma: The following statements are true concerning mechanism of nitrate's
A. Beta 1 Adrenergic beneficial clinical effect, except?
B. Muscarinic Cholinergic A. Decreased myocardial oxygen requirement
C. Beta 2 Adrenergic
B. Relief of coronary artery spasm
D. Nicotinic Cholinergic C. Improved perfusion to ischemic myocardium
When giving antilipidemics, what should be frequently monitored? SATA
D. Increased myocardial oxygen consumption
A. Kidney function
B. Liver function Indicate the drug belonging to antagonists of heparin
C. Lipid profile
A. Aspirin
D. Creatinine B. Phytomenadione
C. Dalteparin
Antidote for Digoxin toxicity
D. Protamine sulfate
A. Immune fab
B. Vitamin k Drugs most commonly used in chronic heart failure are: SATA (may kulang)
C. Phytomenadione A. Cardiac glycosides
D. Protamine Sulfate B. Diuretics
C. ACE inhibitors
All of the following statements regarding cardiac glycosides are true,
D. Calcium channel blocker
except?
A. They inhibit the activity of the Na+ K+ ATPase This drug is a class II antiarrhythmic drug
B. They decrease intracellular concentrations of calcium A. Flecainide
in myocytes B. Propanolol
C. They increase vagal tone C. Lidocaine
D. They have a very low therapeutic index
D. Verapamil
All of the following are recommended at the initial stages of treating NSAIDs can be given to which of the following patient:
patients with heart failure, except A. Patient who had a Percutaneous Coronary Intervention
A. Reduced salt intake (PCI) in for the management of Myocardial Infarction.
B. Verapamil B. 34 year old male who had experience joint pains and
C. Captopril di ko sure pero sabi nung isang classmate eto muscle aches after an activity
daw C. 20 years old female who is experiencing idiopathic
D. Furosemide bleeding over her gastrointestinal tract showing a
significant low hemoglobin.
Antilipidemics can be given alone to patients with elevated cholesterol? D. 3 years old male who had a history of asthma.
A. True
B. False
Which of the following is an opioid analgesics?
All of these drugs are antiplatelet agents, except A. Mefenamic Acid
A. Aspirin B. Meperidine
B. Urokinase C. Aspirin
C. Ticlopidine D. Ketorolac
D. Clopidogrel

These medications are given to prevent further clotting Which of the following is a local anesthetic?
A. Heparin A. Sevorane
B. Aspirin B. Midazolam
C. Clopidogrel C. Lidocaine
 D. Dormicum
The following are the adverse/side effect of Corticosteroids (steroids)
except:
A. Hyperglycemia
B. Infection
C. Weight loss
D. Cushing Syndrome
The patient is having an active bleeding and has a pain scale of 5/10.
Which of the following medications should not be given to the patient:
(Select all that apply)
A. Aspirin
B. Mefenamic Acid
C. Ketorolac
D. Paracetamol
Which of the following is NOT true regarding NSAIDs:
A. This should be given with foods.
B. Enteric coated tablets should not be crushed and must
be swallowed.
C. It is the drug of choice for patient who experience
osteoarthritis and renal dysfunction.
D. NSAIDs should be use cautiously with pregnant women
Corticosteroids cannot cause gastric irritation?
A. True
B. False
C. I don't know..
The ultimate goal of pain management is:
A. Freedom from pain
B. Use the medication according to its indication
C. Prevent the occurrence of toxicity and dependency
A teenager, a known asthmatic, is admitted to the medical unit. The
patient came in due to shortness of breath and difficulty of breathing.
Upon assessment, there is a wheezing sound at the bilateral lungs. What
medication would warrant the nurse’s attention?
A. Mefenamic acid
B. Heparin
C. Cefazolin
D. Montelukast
Opioid agonist act in the central nervous system by the means of:
A. Mimicking the effects of natural pain reliever of the
body such as endorphins.
B. Inhibiting prostaglandin synthesis in the peripherals.
C. Antagonizes the effects of opioid in the receptor sites.
D. Inhibits stimulation of arachidonic pathway and the
release of prostaglandins.
Which of the following is true about steroids:
A. After the duration of treatment, the patient may
immediately discontinue the steroid treatment.
B. People who are on steroid therapy may stay with
immunocompromised patient such as cancer patients.
C. It can be taken with or without meals.
D. Blood pressure is not affected in steroid therapy.
Patient X will be undergoing a coronary artery bypass graft (CABG), which
medication should be withheld?
A. Penicillin
B. Paracetamol
C. Dormicum
D. Aspirin
Pain can be acute or chronic?
A. True
B. False
C. Depends on severity
A 35 year old male patient who had major operation and continuously
reports pain. He has a standing order of morphine 1mg IV every 4 hours.
As a nurse in charge to the patient, you must:
A. Hook the patient to ECG monitor
B. Count the respiratory cycle for 1 whole minute
C. Assess the oxygen saturation
D. Assess for any signs of bleeding
A patient diagnosis with rheumatoid arthritis is on Methotrexate. While on
drug therapy, the patient experience flu like symptoms, sore throat and
decrease in complete blood count. This event is:
A. Pancytopenia
B. Allergic Reactions
C. Drug is eliciting its effectiveness
D. Infections
The client with myasthenia gravis who is taking Tensilon develops a
sudden increase in weakness, accompanied by an increase in heart rate
from 76 to 100 beats/min and an increase in blood pressure from 122/72
to 152/82. What conclusion can the nurse make from these findings?
A. The client’s condition is responding to treatment.
B. The client is experiencing myasthenic crisis.
C. The client is experiencing cholinergic crisis.
D. The client is experiencing a mixed crisis.
Nurse Shane is preparing a client newly diagnosed with multiple sclerosis
for discharge home from a rehabilitation center. The client has been
prescribed cyclophosphamide and methylprednisolone. What should be
included in a teaching plan for this client?
A. “Try to use physical aids such as walkers as little as
possible.”
B. “Avoid people with colds.”
C. “You may discontinue these medications when your
symptoms improve.”
D. “Take hot baths.”
The client who has experienced status epilepticus treated with IV
diazepam has been ordered to receive phenytoin to prevent a recurrence.
What statement indicates that the client understands how to take this
medication?
A. “Even when my seizures stop, I will take this drug.”
B. “This will stop me from getting an aura before a
seizure.”
C. “I will not be able to be employed while taking this
medication.”
D. “I must drink at least 2 L of water daily.”
Which of the following medication is the drug of choice for cholinergic
crisis?
A. Albuterol
B. Atropine
C. Hydantoin
 D. Dopamine A. Seizures, tremors, diaphoresis
B. Blurred vision, anorexia, dysarthria
C. Ataxia, sedation, dizziness
A client with multiple sclerosis has been treated for 6 months with D. Libido changes, edema, dystonia

mitoxantrone (Novantrone). What clinical manifestation would alert Nurse

Carol to an adverse effect of this medication? The nurse is teaching a child and the family about the medication
A. Black, tarry stools
B. Crackles in the lungs phenytoin (Dilantin) prescribed for seizure control. Which of the following
C. Nausea and vomiting after meals
D. Periorbital edema side effects is most likely to occur?
A. Drowsiness
B. Vertigo
The area of the brain responsible for conscious thought, intellect, memory C. Gum hyperplasia
D. Vomiting
storage and processing, controlling the movement of skeletal muscles, and

sensation is the:
A. Cerebellum. The client is prescribed phenytoin (Dilantin) for treatment of a seizure
B. Cerebrum.
C. Medulla oblongata. disorder. What precautions or instructions should be taught to this client?
D. Thalamus. A. “Avoid direct exposure to sunlight while on this
medication.”
B. “Do not take warfarin (Coumadin) while on this
medication.”
A client presents with an acute exacerbation of multiple sclerosis. Which C. “Do not take aspirin or aspirin-containing products
while on this medication.”
drug should the nurse be prepared to administer? D. “Avoid contact sports and heavy physical exercise while
A. Dantrolene sodium, a hydantoin derivative on this medication.”
B. Baclofen, a skeletal muscle relaxant
C. Betaseron, an immunosuppressive agent
D. Methylprednisolone, a glucocorticoid
A female client who has a history of seizure went to a health care facility to

ask the nurse regarding the use of birth control pills while on phenytoin
The client asks the nurse why he is taking bromocriptine (Parlodel), a
therapy. The nurse correctly states to the client that:
Parkinson’s disease medication. The nurse’s reply is based in the A. Taking phenytoin decreases the effectivity of the birth
control pills.
understanding that bromocriptine mimics the effects of dopamine by: B. Pregnancy is not allowed while taking phenytoin.
A. Activating dopamine receptors in the brain C. To discontinue phenytoin and proceed with the oral
B. Decreasing the storage of dopamine peripherally contraceptive.
C. Decreasing dopamine levels in the brain D. There is no known interaction between these
D. Inhibiting monoamine oxidase type B medicines so there is nothing to worry about.

The white fatty substance that coats axons to increase signal speed is: The entire central nervous system is divided into two main regions: The
A. Adipocytes
B. Myelin _________
C. Microfibrils A. Brain and the spinal chord
D. Dendrites B. Neurons and the glial cells
C. Motor neurons and the sensory neurons
D. None of the above
When caring for a client who is receiving phenytoin, an anti-seizure

medication, and warfarin (Coumadin), an anticoagulant, the nurse would
expect which of the following drug-drug interactions?
A. Decreased effectiveness of phenytoin
B. Increased effectiveness of warfarin
C. Decreased effectiveness of warfarin
D. Increased effectiveness of phenytoin
The nurse evaluates that carbidopa and levodopa (Sinemet), a Parkinson’s
Disease medication, is therapeutically effective if the client has:
A. Increased tolerance to pyridoxine
B. Increased urinary output
C. Decreased tremors at rest
D. Decreased GI responses

Both the depolarization and repolarization changes that occur during the Amphetamines, should never be given in combination with:
A. Antihypertensives
action potential are produced by:
B. MAO inhibitors
A. Small neuroglial cells that act as batteries for the
C. Oral hypoglycemics
neuron itself
D. Insulin
B. Ions moving across the cell membrane
C. Enzymes creating new ions
D. Negative stimuli
The client is experiencing status epilepticus. Which of the following drugs

should Nurse Jelai ready to administer?

When monitoring a client who is taking benzodiazepines, the nurse should A. Atropine
B. Propranolol
be alert for which CNS side effects?
C. Lorazepam
 D. Theophylline

The daughter of a client with Alzheimer’s disease asks if the medication

her mother is taking for AD will improve the client’s dementia. What is the

nurse’s best response?

A. “The medication is used to halt the advancement of AD
but will not cure it.”
B. “Medications do not improve dementia but help
control emotional responses.”
C. “You will see slow but steady improvement in memory
but not in problem solving.”
D. “The medication will help your parent live
independently once more.”

Nurse Frances is caring for a client with a history of epilepsy who suddenly

begins to experience a tonic-clonic seizure and loses consciousness. What

would be her best action?

A. Take the client’s blood pressure.
B. Restrain the client’s extremities.
C. Place an airway into the client’s mouth.
D. Administer benzodiazepine as ordered.

Denny is diagnosed with attention deficit disorder. Which of the following

drugs is commonly used for his condition?

A. phendimetrazine (Adipost), an appetite suppressant
B. methylphenidate (Ritalin), an amphetamine
C. diethylpropion (Nobesine), a sympathomimetic amine
and anorectic agent
D. caffeine, a CNS stimumant

The nurse would monitor for decreased effect of amphetamines when

these drugs are given with:

A. All of the above
B. Antidiabetic agents
C. Caffeine
D. Tricyclic antidepressants

A depressed client is experiencing severe insomnia. The health care

provider orders trazadone (Desyrel), an antidepressant with a sedative

effect. The nurse tells the client to expect:

A. Improvement of acne
B. Reduced arthritic pain
C. Less nasal stuffiness
D. Relief of insomnia

When administering IV phenytoin (Dilantin), an anti-seizure medication,

the nurse should:

A. Administer it at a rate 100 mg/min.
B. Mix the drug in dextrose solution.
C. Mix the drug in saline solution.
D. Protect the drug from light exposure.