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RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

(Schematic Diagram)

Systemic blood
pressure drops

decreased filtrate
volume, renal perfusion
and ECF volume deficit
(↑ thirst and water
intake)

↑ production of
juxtaglomerular cells
of kidneys

Renin production

↑ angiotensin I
production

angiotensin II formed
in the blood

stimulates adrenal
vasoconstriction of
cortex
the blood vessels

↑ peripheral resistance aldosterone secretion

↓ NA⁺ and H2O


excretion

↑ blood volume

↑ blood pressure
(hypertension)

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