300 million people

the leading cause of

disability worldwide.
• 9% of patients in primary care settings

• 30% of acutely hospitalized adults

• 40% of older patients in long-term care

• 80% of severely depressed patients think of suicide

Biological
Psychological

DEPRESSION

Social Spiritual
Biological Psychological

MOOD
DISORDER

Social Spiritual
Biological Psychological

MOOD
DISORDERS

Social Spiritual
Biological Psychological

MOOD
DISORDERS

Social Spiritual
Loss of interest or pleasure in
almost all activities
Appetite Weight
Diminished ability to concentrate
• Classic appearance
• Mood

• Speech
• Perceptual disturbances
• Thought content

• Cognition
• Impulse control
• Judgment and insight
• Reliability
Flight of ideas/Racing thoughts
• Mood
• Speech
• Perceptual disturbances

• Thought

• Sensorium and cognition

• Impulse control
• Impaired judgment
• Reliability
Mania

Hypomania

Euthymia

Minor Dep

Major Dep
1 2 3 4 5
Major Depressive Disorder Bipolar I Disorder Bipolar II Disorder Cyclothymia Dysthymia
Biological Psychological
Major Depressive Disorder
• Selective Serotonin
Reuptake Inhibitors (SSRI)
• Serotonin-Norepinephrine
Reuptake Inhibitors (SNRI)
• Tricyclic antidepressants
MOODBipolar Disorder
• Lithium
DISORDER• Anticonvulsant Mood
Stabilizers –
Carbamazepine, Valproate,
Lamotrigine
• Atypical Antipsychotics –
adjuncts
• Benzodiazepines - adjuncts
Biological Psychological

MOOD
DISORDER
Psychotherapies:
• Cognitive Therapy
• Interpersonal Therapy
• Behavior Therapy
• Psychoanalytically Oriented Therapy
• Family Therapy
Biological Psychological

MOOD
DISORDER
Hospitalization indications:
• Risk for suicide or homicide
• Grossly reduced ability to get food
• Need for diagnostic procedures for
uncooperative patients
• History of rapidly progressing features
• Breach in the patient’s usual support
systems
Biological Psychological

MOOD
DISORDER