This document provides guidance on performing a newborn neurological examination, including assessment of various cranial nerves. Key points include:
- Cranial nerve I (olfactory nerve) is assessed by observing changes in behavior, respiration or heart rate in response to irritants like ammonia or vinegar.
- Cranial nerve II (optic nerve) is assessed using the optic blink reflex and observing visual tracking of light.
- Cranial nerve III, IV and VI (oculomotor, trochlear and abducens nerves) are assessed together by observing pupil size, shape and symmetry, light reflexes, and eye movements during visual tracking.
- Cranial nerve V (trigeminal nerve)
This document provides guidance on performing a newborn neurological examination, including assessment of various cranial nerves. Key points include:
- Cranial nerve I (olfactory nerve) is assessed by observing changes in behavior, respiration or heart rate in response to irritants like ammonia or vinegar.
- Cranial nerve II (optic nerve) is assessed using the optic blink reflex and observing visual tracking of light.
- Cranial nerve III, IV and VI (oculomotor, trochlear and abducens nerves) are assessed together by observing pupil size, shape and symmetry, light reflexes, and eye movements during visual tracking.
- Cranial nerve V (trigeminal nerve)
This document provides guidance on performing a newborn neurological examination, including assessment of various cranial nerves. Key points include:
- Cranial nerve I (olfactory nerve) is assessed by observing changes in behavior, respiration or heart rate in response to irritants like ammonia or vinegar.
- Cranial nerve II (optic nerve) is assessed using the optic blink reflex and observing visual tracking of light.
- Cranial nerve III, IV and VI (oculomotor, trochlear and abducens nerves) are assessed together by observing pupil size, shape and symmetry, light reflexes, and eye movements during visual tracking.
- Cranial nerve V (trigeminal nerve)
Script : Red ■ 37 weeks old = Turn head and eyes to source of
Additional notes: Blue light
General Assessment ■ Ophthalmoscope examination is done at Phase 3 ● First we observe while the patient is seated in the parent’s because it is invasive lap. While talking to the parents, inspect the size of the head, ■ We check for the Red retinal fundus reflex, failure stance, body and note any asymmetry. Observe for any skin to see a red orange red reflex may indicate lesion. congenital cataract, congenital glaucoma or ● Mental Status Exam retinoblastoma. We also note retinal ● Observe the patient and undress with permission from the hemorrhages. parents. ■ For the ophthalmoscopic examination, with the ○ (Importance of seeing the child undressed: to see the newborn awake and eyes open, examine the red movement of both the arms and legs) retinal (fundus) reflex by setting the ● Look at the waking patterns, if asleep assess the resting ophthalmoscope at 0 diopters and viewing the posture, if awake introduce a noise and look at the facial pupil from about 10 inches. Normally, a red or expression and the movement of the head. orange color is reflected from the fundus through ○ Sensorium/Level of Alertness the pupil. A thorough ophthalmoscopic ○ Cognitive Functions examination is difficult in young infants but may be ■ Demonstrate expected social behavior needed if ocular or neurologic abnormalities are ■ Elicit developmental milestones?? noted. The cornea can ordinarily be seen at +20 ■ Play behavior and activity diopters, the lens at +15 diopters, and the fundus ● Head at 0 diopters. ○ First we are going to inspect the head and look for any ■ Congenital glaucoma may cause cloudiness of signs of flattening of the occiput on one side (most the cornea. common), premature closure of sutures ■ A dark light reflex can result from cataracts, (craniosynostosis) retinopathy of prematurity, or other disorders. ○ Next is we palpate the sutures and check for any ■ A white retinal reflex (leukokoria) is abnormal, and premature closure as well as palpate the fontanelles cataract, retinal detachment, chorioretinitis and note any bulging (indication of high pressure that suggests intrauterine infection (salt and pepper can be caused by edema eg hydrocephalus) pigmentary changes, or should be suspected ■ anterior fontanelle closure - 10-20 mos ■ Hemorrhages are commonly detected after ■ posterior fontanelle - 3 months vaginal delivery, even in the absence of traumatic ○ Then we determine the circumference of the head using delivery. Retinal hemorrhages may be found in a a tape measure. We measure the occipitofrontal large percentage of otherwise normal infants who circumference and this is done last because children have no history of abnormal delivery and who later get restless if their head movement is restricted. prove to be neurologically normal. ○ Head size ■ They are usually small and multiple, and their ○ Fontanel presence does not necessarily indicate intracranial ○ Sutures bleeding. ○ Scalp swelling ○ Auscultation ○ CN III, IV, VI ○ Transillumination ■ Describe size and shape of pupils; check for ● Spine – check for neural tube defects etc. ptosis, lid lag or retraction ○ We observe the patient and look for any signs of spinal ● First part involves observation; describing and back deformities as well as search for any tufts of the size, shape and symmetry of pupils. You hair, bulgings or openings along the spine. should also check if there is presence of ● Cranial Nerves ptosis or nystagmus. ○ CN I (menkes/swaiman) ■ Direct and consensual pupillary light reflex ■ note the change in behavior or change in ● Normal Report: Both pupils are briskly respiratory or heart rate reactive to light meaning constriction was ■ Functional by 5-7 months observed upon illumination. ■ It is infrequently accessed because it is functional ■ Extraocular muscles movement by 5-7 months of age. ● With the use of a bright object, test the EOMs ■ By contrast, newborns do respond to inhalation of and observe the patient’s gaze as he/she irritants, such as ammonia or vinegar, because the follows the object. reflex is transmitted by the trigeminal nerve; ● Normal Report: The patient was able to hence, this reflex is preserved in the infant with follow the direction of the object indicating arhinencephaly intact EOMs ■ (baka itanong) olfactory pathway: olfactory ○ CN V (Source: Bates) receptors → collectively (CN1) → olfactory tract ■ Motor: Test the rooting reflex by gently stroking the → olfactory cortex → olfactory information perioral skin at the corners of the mouth and ○ CN II (bates) sucking reflex observed when the baby is feeding. ■ We assess the visual acuity by using the optic Also take note of the strength of the suck. blink reflex, the newborn blinks in response when ■ Sensory: Not yet elicited on neonates shown a bright light at 1 month of age can fixate ■ Tests for pain and sensation are imprecise at this on an object. age, and the gross response of infants to stroking ■ The newborn infant follows toward a light or a and pinprick with withdrawal, crying, and change bright object during an alert period in sucking rates may be the only information ■ Visual acuity possible. More sophisticated testing can be ■ Term infants → 20/150 devised during which heart and respiratory rates ■ 6 months → 20/20 are monitored (SWAIMAN'S) ■ 28 weeks old = (N) PM infant blinks ○ CN VII (Source: Bates) ■ 32 weeks old = Eye closure maintained until light ■ Motor: Observe the baby’s crying and smiling while source is removed assessing the symmetry of the nasolabial folds, forehead and even eye closure. Take note that cranial VII innervates all muscles of facial ● Another way of testing this is we will give the movements and expression. neonate a bottle of milk which will elicit ■ Sensory: Not yet elicited on neonates swallowing and gag reflex. ■ Facial movements are readily observed during ● If there is no spillage of milk, it means that the crying. neonate has an intact CN 10 ■ Asymmetry should be carefully assessed to determine whether it is related to an upper motor ■ CN XI (Spinal Accessory Nerve) neuron lesion (such as the so-called central ■ Infants – observe head movements seventh nerve palsy causing contralateral lower ● Observe the head movements of the neonate face weakness), a peripheral nerve lesion ■ Cannot assess adequately during infancy (causing unilateral weakness of both the upper ● Since muscles (SCM and Trapezius muscle) and lower face), or a muscle problem such as are still underdeveloped hypoplasia of the depressor anguli oris that causes ■ Ask for the consent of the mother to undress the weakness of a lower lip and is also referred to as child until to the torso or ask the mother to do this asymmetric crying facies (SWAIMAN'S) for the newborn. Once consent is given, ask the ○ CN VIII mother to lift the newborn ■ Use noise makers/rattles, infants will turn head or ■ When the mother lifts the baby, observe for the tilt head towards the source, startle response or an symmetry the upper trapezius muscle (Bates) and increase in their state of alertness. if there is no involuntary movements, ■ CN VIII mediates hearing and vestibular function, fasciculations or atrophy (difficult to assess) - (BATES TABLE page 847) Test for acoustic blink SWAIMAN, then CN 11 is intact reflex or tracking in response to sound, by using a noisemaker or rattle, neonate will turn their head ○ CN XII (Hypoglossal Nerve) or tilt their head towards the source, startle ■ Examine bulk and power of tongue. Atrophy, response or an increase in their state of alertness, deviation from midline with protrusion (Check both ears L&R). Patient respond well to ■ Check for involuntary movements sound indicates intact cranial nerve VIII. ● We will examine the tongue using a gloved ■ Normal: Startle/blink in response to sound, turn finger and put it in the neonate’s mouth to head towards source stimulate the mouth of the baby to open and CN VIII: Hearing is normally present in term to protrude his tongue babies, Neonates blink or startle with loud noise - ● Once it is open, gently squeeze the Blue book neonate’s cheeks to get a better visualization - In a normal newborn, pause briefly during of the baby’s mouth and observe for its sucking when bell is presented; after several motility, size, shape and atrophy (OSCE PD- stimulations, the pauses stop as habituation PEDIA Neurological exam) and look at the occurs (use of bell or other noise). base (underside) and lateral margins of - No habituation occurs for neurologically tongue (SWAIMAN) for presence of abnormal infants. - PD PEDIA Neuro fasciculations since usually it is located here ■ Asymmetry or loss of tongue bulk may indicate ○ CN IX, X abnormalities of CN 12 or its nucleus (Swaiman) ■ Observe while baby is feeding milk ■ Note quality of the cry ● Sensory Examination ■ Elicit the gag reflex ○ Perioral tactile sensation can be evaluated by the ■ Has both sensory and motor function. For cranial rooting response in which gentle stroking of the cheek nerve IX (Glossopharyngeal Nerve), this usually results in the infant turning towards stimulus with an innervates the posterior ⅓ of the tongue. We open mouth ready to latch onto the object (UpToDate) observe the uvula and soft palate when a neonate cries as well as the gag reflex ● Motor Examination ● The uvula and palate usually elevates when ○ Assess the motor tone, observe their position at rest a neonate cries and if there is a vagal nerve and their resistance to passive movement. To further problem, the uvula will deviate toward the assess the tone, apply gentle manipulation of the UNaffected side (PD PEDIA NEURO) infant’s limbs and note any spasticity or flaccidity. ● Sucking - tests for strength of masseter and ○ When held in the vertical position, the hypotonic and temporalis muscles (OSCE PD PEDIA) weak infant tends to slide through the examiner’s ● Swallowing dysfunction requires close hands. In the horizontal position, the hypotonic infant scrutiny to determine which cranial nerve or droops over the examiner’s arms without raising head nerves are involved (CN 5,7,9,10 and 11). (SWAIMAN) or legs. ● For CN 10 (Vagus nerve), we don’t need to ○ To test the arm traction, take the arm and gently pull make the neonate cough, hearing the until the shoulder is slightly off the mat. There should be neonate cry loudly this signifies that the some flexion maintained at the elbow. neonate has an intact CN 10 ○ For the arm recoil, the forearms are flexed for few ● Apply gentle pressure to the trachea or seconds, then fully extended, and then released. The suprasternal notch to test for cough in newborn (PD PEDIA NEURO) arms should return to the flexed position. ● The quality and strength of the cry is a way ○ Tone of the shoulder girdle with the scarf sign; take of looking at (CN IX) Cranial Nerves 9 and the baby’s hand and pull the opposite shoulder like a (CN X) 10 function.(Neuro Exam - Newborn cranial scarf. The hand should not go past the shoulder and the nerves - Embryology. (n.d.). Embryology.Med. Retrieved elbow should not cross the midline of the chest. November 10, 2020, from https://embryology.med.unsw.edu.au/embryology/index.p ○ For the leg traction, hold the leg by the ankle and pull hp/Neural_Exam_-_Newborn_cranial_nerves) upward until the buttock is lifted off the mat. The knee ● A neonate with generally depressed CNS should maintain a flexed angle. function often cries infrequently (SWAIMAN) ○ To test leg recoil, the legs are fully flexed, then the legs in the newborn infant, an extensor plantar response are quickly extended and released. The legs should (Babinski) may be physiologic and may persist for several months. spring back to the flexed position. ○ Primitive Reflexes (palmar to galant reflex - bates & ○ To assess the popliteal angle. Flex the thigh fully, and menkes) extend the leg at the knee. The angle between the thigh ■ Palmar grasp - Touch the palmar surface of the and the leg is typically about 90 degrees. Extension of neonate and the positive response for this is the the leg beyond 90 to 120 degrees would be seen in fingers of the neonate will curl around your finger. hypotonia. Present at birth to 4-5 months. ■ Plantar grasp - Touch at the base of the toes, and ○ Source: SWAIMAN'S PEDIATRIC NEURO the neonate will respond by curling his/her toes ○ Check videos here: around your finger. Present at birth to 9-12 months https://embryology.med.unsw.edu.au/embryology/inde ■ Rooting reflex - Stroke the perioral skin at the x.php/Neural_Exam_-_Newborn_positions_- corners of the mouth then the neonate is expected _vertical_suspension to respond by opening his/her mouth, turning on to the stimulated side and begin to suck. Present at ● Reflex Examination (bates) birth until 3-4 months ○ Tendon Reflexes ■ Moro reflex (aka Startle reflex) - Make sure to ■ Biceps − Elbow flexed, tapping the biceps tendon in the support neonate’s head and back, including the antecubital fossa leads to flexion at the elbow. ■ Knee (patellar) − Tapping the quadriceps tendon below legs. Abruptly lower the entire body for about 2 the patella leads to extension of the knee. meters. The positive response for this: the arms ■ Ankle - slightly dorsiflex the ankle, strike the will abduct, extend, the hands will open, and the achilles tendon legs will flex. ■ Alternative way is to grab the neonate’s malleolus, ■ Tonic neck response - Put the neonate in a supine then slightly dorsiflex the ankle position, then turn the head into one side holding ■ A rapid, rhythmic, plantar flexion of the foot can be the jaw over the shoulder. The positive response noted. up to 10 beats normal in neonate; this is for this test is that the arm and leg on the side unsustained ankle clonus where the head is turned will extend, while the ■ Triceps and brachioradialis reflexes are not tested opposite arem and leg will flex. Appears at birth as they are difficult to elicit before 6 months of age and persists until 2 months. ■ DTR are variable in newborns and infants because ■ Galant reflex (Truncal incurvature) - Support the CST pathways are not fully developed infant prone with one hand. Stroke one side of the ■ Their exaggerated presence or absence has little back 1cm from the midline and from the shoulder diagnostic significance, unless this response is to the buttocks. Notice that the positive response different from results of previous testing or extreme for this is the spinal curves towards the stimulated responses are observed side. Appears at birth and persists until 2 months. ■ Grading of DTR ■ Landau reflex - done by suspending the baby ○ Areflexia 0 prone with one hand and flex the baby’s head ○ Hyporeflexia 1 down. Normal response is that the baby’s head will ○ Normal 2 lift up and the spine will straighten. Seen from birth ○ hyperreflexia 3 until 6 months ○ Clonus present 4 ■ Parachute reflex - done by suspending the baby ● *not performed: prone and slowly lowering the head toward a ○ Jaw − Tapping the chin with the mouth slightly open surface. Normal response is the baby will leads to slight jaw closure. spontaneously extend the upper extremities in a ○ Brachioradialis (supinator) − Tapping above the protective manner. This begins from 8 months and wrist on the radial aspect of the forearm leads to does not disappear. flexion at the elbow. ■ Positive Support Reflex - done by holding the baby ○ In the newborn, it may be difficult to elicit the around the trunk and lowering the baby until the triceps reflex because of strong flexion of the feet touches a flat surface. Normal response is elbows in the normal neonatal resting posture. when the hips, knees and ankles extend, the baby ○ Superficial Reflexes will stand up partially bearing weight and sags after ■ Abdominal reflexes in four quadrants of the abdomen 20-30 secs. Seen from birth or 2 months until 6 are elicited by gentle stroking in an axial to peripheral months. direction, resulting in contraction of the abdominal wall. ■ Placing and Stepping reflex - Hold the baby upright The absence of response may be consistent with an as in the positive support reflex. Bring the dorsi of ipsilateral pyramidal tract lesion. the feet against the under edge of the table top. ■ Cremasteric reflex in males can be demonstrated by Normal response is that upon contact, the hip and stroking the inner thigh area in an anterior to posterior direction, which results in ipsilateral scrotal retraction and knee of that foot will flex and the other foot will step testicular rise due to contraction of the scrotal dartos forward and alternate stepping occurs. muscle. The lack of response or an asymmetrical response may be consistent with a corticospinal tract ● Cerebellar Function abnormality. ○ Hypotonia is characterized by reduced resistance to ■ Anal wink reflex is elicited by gentle stroking of the passive range of motion in joints. It can be tested from perianal region, which results in contraction of the the earlier examinations and can be tested further by perianal muscle. The absence of an anal reflex suggest manipulation of the limbs (examine all 4 limbs. (+) loss of innervation of the external sphincter muscle hypotonia = freely moving joint; check symmetry and caused by spinal cord abnormalities such as: ● Spina bifida trunk tone). The baby should also be suspended in the ● Tumor supine, lateral and prone position on the examiner’s ● Injury hand. ■ Babinski reflex ○ Observe the posture of the child in bed. (+) floppy child Using an applicator stick or tongue blade, slowly stroke = frog like position (hips abducted, knees flexed). the lateral side of the patient’s sole from the heel to the Palpation: feel the muscle (+) hypotonic muscle = soft great toe. and flabby. ○ Horizontal/Ventral suspension: (+) hypotonia when baby assumes the rag doll posture or “U” posture in a horizontal suspension ○ Vertical suspension/Rag doll gait: (+) hypotonia when infant “slips through” at the shoulders when the examiner grasps the baby under the arms in an upright position ○ (+) hypotonia if there is significant head lag with traction when pulled up from the supine to the sitting position ○ Pendular quadriceps reflex same with the knee (patellar) reflex. Place your hand under the knee and the leg at about 90 degree angle at the knee. Strike the patellar tendon with the reflex hammer using a pendular action rather than a chopping action. ○ Nystagmus - Inspect the baby’s eye and let the baby follow your finger/toy through field of gaze