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  • Treatment of Psoriasis

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    iman
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    The document discusses treatment options for psoriasis based on disease severity. For limited disease, topical corticosteroids, vitamin D analogs, tar, topical retinoids, tacrolimus or pimecrolimus are recommended. For moderate to severe disease, phototherapy, systemic therapies including retinoids, methotrexate and cyclosporine are used. Biologic immune modifying agents that target TNF, IL-12/IL-23, IL-17 and IL-23 are also used for more severe cases.

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    Treatment of Psoriasis

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    The document discusses treatment options for psoriasis based on disease severity. For limited disease, topical corticosteroids, vitamin D analogs, tar, topical retinoids, tacrolimus or pimecrolimus are recommended. For moderate to severe disease, phototherapy, systemic therapies including retinoids, methotrexate and cyclosporine are used. Biologic immune modifying agents that target TNF, IL-12/IL-23, IL-17 and IL-23 are also used for more severe cases.

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    © All Rights Reserved
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    10 views1 page

    Treatment of Psoriasis

    Uploaded by

    iman
    The document discusses treatment options for psoriasis based on disease severity. For limited disease, topical corticosteroids, vitamin D analogs, tar, topical retinoids, tacrolimus or pimecrolimus are recommended. For moderate to severe disease, phototherapy, systemic therapies including retinoids, methotrexate and cyclosporine are used. Biologic immune modifying agents that target TNF, IL-12/IL-23, IL-17 and IL-23 are also used for more severe cases.

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    © All Rights Reserved
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    Treatment of Psoriasis

    Limited disease:
    - Topical corticosteroids
    - Vitamin D analogs, such as calcipotriene and calcitriol
    - Tar
    - Topical retinoids (tazarotene)
    - Topical tacrolimus or pimecrolimus (for facial or intertriginous areas)
    - Localized phototherapy (for recalcitrant disease)
    - Combinations of potent topical corticosteroids and either
    calcipotriene, calcitriol, tazarotene, or UVB phototherapy

    Moderate to severe disease:


    - Phototherapy
    - Systemic therapies:
    - Retinoids, methotrexate, cyclosporine, apremilast
    - Biologic immune modifying agents:
    - Anti-tumor necrosis factor (TNF) agents (adalimumab, etanercept, infliximab)
    - Anti-interleukin (IL)-12/IL-23 antibody (ustekinumab)
    - Anti-IL-17 antibodies (secukinumab and ixekizumab)
    - Anti-IL-17 receptor antibody (brodalumab)
    - Anti-IL-23/IL-39 antibodies (guselkumab and tildrakizumab) 

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