DELA CRUZ, KIMBERLY H.

BSN II – FAYE ABDELLAH

AGO ANTA
NIST GONIST
AGONIST
 Ligands that activate a receptor to produce a biological response. An agonist is It increases
 A drug which imitates the action of neurotransmitters in the brain. something that cellular function
causes a specific
 A muscle whose contraction moves a part of the body directly. if they block the
physiological action of a
 DRUG: methadone
response in substance that
the cell normally decreases
 Both agonists and antagonists have to be structurally similar to the  Cellular function
in order to fit into the active site of the receptor
 Both receptor sites Those molecules
Are drugs that bind
 Both are key players in the chemistry of the human body and in that bind to
to cell receptors
pharmacology. specific receptors
and cause a that prevent the 
 DRUG: Both used to treat opioid addiction process in agonists from
ANTAGONIST the cell to become eliciting biological
more active. response. 
 Ligands that block agonist mediated responses
 A drug the blocks neurotransmitters.
 A muscle whose action counteracts that of agonist.
Examples of Examples are
 DRUG: Naltrexone
full agonists are naltrexone and
heroin, oxycodone, naloxone. Naloxone
methadone, is sometimes used
hydrocodone, to reverse a
morphine, opium heroin overdose.
and others.