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Infectious Disease [EARS NOSE THROAT]
5) Pharyngitis Modified Centor (aka “McIsaac”) Criteria
Much like sinusitis, viral pathogens are the most common cause C Absent Cough +1
occurring in kids and adults. The primary complaint will be sore throat E Exudates (tonsillar) +1
with pain on swallowing. Some exam findings (pharyngitis plus N Nodes = Anterior Chain +1
conjunctivitis = adenovirus; pharyngitis plus rash on palms/soles = Lymphadenopathy
coxsackie) can help point towards a specific pathogen. Because a T Temp > 38°C +1
bacterial infection with Group A Strep (GAS) can cause rheumatic OR < 14 yrs old or +1
fever if untreated, diagnosing and treating this is important. Post-strep > 44 yrs -1
glomerulonephritis (PSGN) can still happen even if you get treated for
Strep A Pharyngitis. The symptoms are the same whether it’s viral or Score Interpretation
bacterial; the job becoming deciding whether to treat empirically, or if <1 No further testing needed
testing is needed first. 2-3 Perform rapid testing
>4 Empiric antibiotics*
There are scoring systems (Centor, Modified Centor) which can *IDSA doesn’t recommend empiric treatment – test first!
indicate the next step for the patient – supportive care, test for GAS, or
treat for GAS*. Patients under 3 years old have the lowest incidence Group A Strep Pharyngitis Summary
and should not be tested; ages 5-15 years have the highest incidence - Don’t test patients with viral symptoms
so jumping straight to testing in a patient without viral symptoms - Avoid the Centor Criteria in patients under 15
(cough, rhinorrhea) is reasonable. The Modified Centor (aka - Test all patients before treating!
“McIsaac”) criteria attempt to take the higher incidence of the younger - Rapid test has high specificity so confirm negatives
age into consideration.
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