5/11/2020 PhysioEx Exercise 9 Activity 4

PhysioEx Lab Report

Exercise 9: Renal System Physiology
Activity 4: Solute Gradients and Their Impact on Urine Concentration
Name: Nicole de León
Date: 5 November 2020
Session ID: session-bd9c5cfb-d824-a2bf-6621-78726adcf229

Pre-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.

1 As filtrate passes through the nephron, the renal process of reabsorption describes

You correctly answered: the movement of water and solutes from the tubule lumen, into the
interstitial space, and, finally, into the peritubular capillaries.

2 The maximum solute concentration refers to the amount of solutes

You correctly answered: in the interstitial space.

3 Antidiuretic hormone (ADH) affects the permeability of

You correctly answered: the collecting duct.

4 ADH aids the reabsorption of

You correctly answered: water.

Experiment Results
Predict Question
1 Predict Question: What will happen to the urine volume and concentration as the solute
gradient in the interstitial space is increased?

Your answer: The urine volume will increase and the concentration will decrease.

Stop & Think Questions

1 Why is the solute concentration (mOsm) in the proximal tubule the same as in the blood?

You correctly answered: Because water and many plasma solutes filter into Bowman's
capsule.

2 In the presence of ADH, what component of the tubule fluid moves out of the collecting duct
and into the interstitial space?
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You correctly answered: water.

Experiment Data
Urine Volume (ml) Urine Conc. (mOsm) Conc. Grad. (mOsm) ADH
80.57 300 300 present
40.28 600 600 present
26.86 900 900 present
16.86 1200 1200 present

Post-lab Quiz Results

You scored 100% by answering 3 out of 3 questions correctly.

1 Tubule fluid osmolarity will always be the greatest in which of these locations?

You correctly answered: the bottom of the loop of Henle.

2 Tubule fluid volume will always be the greatest in which of these locations?

You correctly answered: the proximal convoluted tubule.

3 Where does ADH directly alter the urine volume?

You correctly answered: in the collecting duct.

Review Sheet Results

1 What happened to the urine concentration as the solute concentration in the interstitial
space was increased? How well did the results compare to your prediction?

Your answer:

Como se observa en los resultados el volumen de la orina disminuyó sin embargo la

concentración fue aumentando conforme aumento la concentración del espacio intersticial
tal, al contrario de como fue la predicción.

2 What happened to the volume of urine as the solute concentration in the interstitial space
was increased? How well did the results compare to your prediction?

Your answer:

Conforme la concentración del espacio intersticial fue disminuyendo el volumen de la orina

fue incrementando y la concentración de la orina fue disminuyendo, tal y como predije.

3 What do you think would happen to urine volume if you did not add ADH to the collecting
duct? i
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5/11/2020 PhysioEx Exercise 9 Activity 4

Your answer:

Si no se añadiera ADH al conducto colector el volumen de la orina debería disminuir debido

a que el ADH estimula la reabsorción del agua reduciendo el volumen de la orina.

4 Is most of the tubule filtrate reabsorbed into the body or excreted in urine? Explain.

Your answer:

Se reabsorbe la mayor parte del filtrado de los túbulos en el cuerpo para prevenir la perdida
de fluidos y mantener la homeostasis.

5 Can the reabsorption of solutes influence water reabsorption from the tubule fluid? Explain.

Your answer:

La reabsorción de solutos afecta la reabsorción de agua porque el agua seguirá al soluto por
ósmosis por lo que, en efecto, la reabsorción de solutos influye en la reabsorción de agua de
los fluidos del túbulo.

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