Activity 2: Please select the letter that matches your thinking:

1. What is the name under which a drug is listed by the U.S. Food and Drug Administration (FDA)?

a. Brand

b. Nonproprietary

c. Official

d. Trademark

2. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological dependency.
Under which classification

does this drug fall?

a. I

b. II

c. III

d. IV

3. The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this drug’s
classification?

a. Abuse potential for this drug is low.

b. Psychological dependency is likely.

c. There is a high potential for abuse.

d. This drug is not a controlled substance.

4. Which of the following terms used to naming drugs depicts the drug’s atomic and molecular
structure?

a. Generic

b. Trade

c. Official

d. Chemical
1. Which of the following refers to the ability of a drug to produce a maximum response
of a tissue after combination with the receptor?
a. Efficacy
b. Intrinsic Activity
c. All of the Above.
d. None of the Above.

2. Which of the following best describes an agonist drug?

a. It is a drug that produces pharmacological effect when it combines with a
receptor.
b. It is a drug that has an affinity only but no intrinsic activity.
c. It is the fraction of the drug that reaches the systemic circulation.
d. It refers to the quantity of the drug needed to produce the therapeutic effect
following administration.

3. A client experiences profound drowsiness when a stimulant drug is given. This is

an unusual reaction for this drug, a reaction that has not been associated with that
particular drug. What is the term for this type of drug reaction?
a. Allergic reaction
b. Idiosyncratic reaction
c. Enzyme-specific reaction
d. Unaltered reaction

4. The provider has ordered atropine, a drug that will prevent the patient’s own
chemical, acetylcholine, from causing parasympathetic effects. What type of drug
would atropine be considered?
a. An antagonist
b. A partial agonist
c. An agonist
d. A protagonist
5. A nursing student reads in a pharmacology textbook that 10 mg of morphine is
considered to provide the same pain relief as 200 mg of codeine. This indicates
that the morphine would be considered more potent than codeine.
(Fill in the blank.)
6. What is the term used to describe the magnitude of maximal response that can
be produced from a particular drug?
a. Efficacy
b. Toxicity
c. Potency
d. Comparability
7. The nurse looks up butorphanol (Stadol) in a drug reference guide prior to
administering the drug and notes that it is a partial agonist. What does this term
mean?
a. It is a drug that produces the same type of response as the endogenous
substance.
 b. It is a drug that will occupy a receptor and prevent the endogenous
chemical from acting.
c. It is a drug that causes unpredictable and unexplained drug reactions.
d. It is a drug that produces a weaker, or less efficacious, response than an
agonist drug.
3. The nurse reads that the drug to be given to the client, has a “narrow
therapeutic index.” The nurse knows that this means that the drug has what
properties?
a. It has a narrow range of effectiveness and may not give this client the
desired therapeutic results.
b. It has a narrow safety margin and even a small increase in dose may
produce adverse or toxic effects.
c. It has a narrow range of conditions or diseases that the drug will be
expected to treat successfully.
d. It has a narrow segment of the population for whom the drug will work as
desired.
4. Which of the following best describes what the Margin of Safety (MOS) of a drug
is all about?
a. Amount of a pharmaceutical that can be given before toxicity first appears
b. Difference between the Effective Dose to 50% of the population (ED50) and
the Toxic Dose to 50% of the population (TD50)
c. Ratio of the Toxic Dose to 1% of the population (TD01) to the Effective Dose
to 99% of the population (ED99)
d. Compare the therapeutically effective dose to the toxic dose of a
pharmaceutical agent

5. Which drug will go through a disintegration process after it is administered?

a. Intramuscular (IM) cephalosporins
b. Intravenous (IV) vasopressors
c. Oral analgesics
d. Subcutaneous antiglycemics

11. The nurse is preparing to administer an oral medication and wants to ensure a
rapid drug action. Which form of the medication will the nurse administer?
a. Capsule
b. Enteric-coated pill
c. Liquid suspension
d. Tablet

12. The nurse is teaching a client who will be discharged home with a prescription for
an enteric-coated tablet. Which statement by the client indicates understanding of the
teaching?
a. “I may crush the tablet and put it in applesauce to improve absorption.”
b. “I should consume acidic foods to enhance absorption of this medication.”
c. “I should expect a delay in onset of the drug’s effects after taking the tablet.”
d. “I should take this medication with high-fat foods to improve its action.”

13. A nurse is preparing to administer an oral drug that is best absorbed in an acidic
environment. How will the nurse give the drug?
a. On an empty stomach
b. With a full glass of water
c. With food
d. With high-fat food

14. The nurse is reviewing medication information with a nursing student prior to
administering an oral drug and notes that the drug has extensive first-pass effects.
Which statement by the student indicates a need for further teaching about this
medication?
a. “The first-pass effect means the drug may be absorbed into systemic circulation
from the intestinal lumen.”
b. “The first-pass effect means the drug may be changed to an inactive form and
excreted.”
c. “The first-pass effect means the drug may be changed to a metabolite, which
may be more active than the original.”
d. “The first-pass effect means the drug may be unchanged as it passes through
the liver.”

15. The nurse prepares to change a client’s medication from an IV to an oral form
and notes that the oral form is ordered in a higher dose. The nurse understands that this
is due to differences in
a. bioavailability.
b. pinocytosis.
c. protein binding.
d. tachyphylaxis.

16. The nurse is preparing to administer a drug and learns that it binds to protein at a
rate of 90%. The client’s serum albumin level is low. The nurse will observe the client for
which of the following?
a. Decreased drug absorption.
b. Decreased drug interactions.
c. Decreased drug toxicity.
d. increased drug effects.

17. The nurse is administering two drugs to a client and learns that both drugs are
highly protein-bound. Which of the following trend should the nurse expect to happen?
a. Decreased bioavailability of both drugs.
b. Decreased drug effects.
c. Decreased drug interactions.
d. Increased risk of adverse effects.

18. A client has been taking a drug that has a protein-binding effect of 75%. The
provider adds a new medication that has a protein-binding effect of 90%. The nurse will
expect which of the following?
a. decreased drug effects of the first drug.
b. decreased therapeutic range of the first drug.
c. increased drug effects of the first drug.
d. increased therapeutic range of the first drug.

19. The nurse gives a medication to a client with a history of liver disease. The nurse
will monitor this client for which of the following?
a. decreased drug effects.
b. increased drug effects.
c. decreased therapeutic range.
d. increased therapeutic range.

20. The nurse gives 800 mg of a drug that has a half-life of 8 hours. How much drug
will be left in the body in 24 hours if no additional drug is given?
a. None
b. 50 mg
c. 100 mg
d. 200 mg

21. The nurse administers a narcotic analgesic to a client who has been receiving it
for 1 day after orthopedic surgery. The client reports no change in pain 30 minutes after
the medication is given. The nurse recognizes that this client is exhibiting
a. drug-seeking behavior.
b. drug tolerance.
c. the placebo effect.
d. tachyphylaxis.

22. A client who takes a drug that undergoes gastric absorption will begin taking an
opioid analgesic after sustaining an injury in a motor vehicle accident. The nurse will
observe the client closely for which effects?
a. Decreased effects of the first drug
b. Increased effects of the first drug
c. Decreased effects of the narcotic
d. Increased effects of the narcotic