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DNA Replication - Labeling: DNA Primase DNA Ligase

The document provides an overview of DNA replication, including key enzymes and structures involved such as DNA helicase, DNA polymerase, and Okazaki fragments. It outlines the order of events during replication and explains why the process is termed 'semi-conservative.' Additionally, it includes a labeling exercise with a word bank for educational purposes.

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0% found this document useful (0 votes)
746 views2 pages

DNA Replication - Labeling: DNA Primase DNA Ligase

The document provides an overview of DNA replication, including key enzymes and structures involved such as DNA helicase, DNA polymerase, and Okazaki fragments. It outlines the order of events during replication and explains why the process is termed 'semi-conservative.' Additionally, it includes a labeling exercise with a word bank for educational purposes.

Uploaded by

Ederlyn Zate
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Name: __________________ Date: ___________

DNA Replication - Labeling (with word bank)

DNA polymerase 3’ 5’ DNA Ligase Okazaki fragment DNA Primase


Single Strand Binding Proteins Helicase Leading Strand Lagging Strand

DNA Ligase DNA Primase

3’

5’
Okazaki fragment

Lagging
Strand

DNA polymerase
Leading
Strand Helicase Single Strand Binding Proteins

Identify the structure


1. DNA Helicase - Enzyme that unwinds DNA
2. Okazaki fragments - Fragments of copied DNA created on the lagging strand
3. Lagging Strand - The strand that is copied in a continuous way, from the 3’ to 5’ direction
4. DNA Ligase - Binds Okazaki fragments
5. DNA polymerase - Builds a new DNA strand by adding complementary bases
6. Single Strand Binding Proteins - Stabilizes the DNA molecule during replication
7. Leading Strand - Strand that is copied discontinuously because it is traveling away from helicase
8. DNA Primase - Initiates the synthesis DNA by creating a short RNA segment at replication fork

9. Place the events in the correct order:


4 DNA polymerase adds nucleotides in the 5’ to 3’ direction
2 Replication fork is formed
3 DNA polymerase attaches to the primer
5 Okazaki fragments are bound together by ligase
1 DNA helicase unwinds DNA

10. Why is replication called “semi-conservative?”


- Since they generate two copies of the original molecule of DNA. There is one initial strand and one newly-
synthesized strand in each copy. (answer may vary)

www.biologycorner.com | Image Credit: Wikimedia Commons


www.biologycorner.com | Image Credit: Wikimedia Commons

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