Gamma Bodkin
Name:____________________________________________ Date:_________
DNA Replication
Identify the structure
DNA Helicase
1. _____________________________ Enzyme that unwinds DNA
Okazaki fragments
2. _____________________________ Fragments of copied DNA created on the lagging strand
Leading Strand
3. _____________________________ The strand that is copied in a continuous way, from the 3’ to 5’ direction
DNA ligase
4. _____________________________ Binds Okazaki fragments
DNA Polymerase
5. _____________________________ Builds a new DNA strand by adding complementary bases
DNA single-stranded binding proteins
6. _____________________________ Stabilizes the DNA molecule during replication
Lagging Strand
7. _____________________________ Strand that is copied discontinuously because it is traveling away from helicase
RNA primase
8. _____________________________ Initiates the synthesis DNA by creating a short RNA segment at replication fork
9. Place the events in the correct order:
4 DNA polymerase adds nucleotides in the 5’ to 3’ direction
____
2 Replication fork is formed
____
____
3 DNA polymerase attaches to the primer
5 Okazaki fragments are bound together by ligase
____
1
____ DNA helicase unwinds DNA
one of the strands of DNA in each of the two copies of DNA
is ancient and conserved while the other is newly produced
at the moment of replication.
10. Why is replication called “semi-conservative?” ___________________________________________________
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Name:____________________________________________ Date:_________
DNA Replication - Labeling (with word bank)
DNA polymerase 3’ 5’ DNA Ligase Okazaki fragment DNA Primase
Single Strand Binding Proteins Helicase Leading Strand Lagging Strand
Identify the structure
1. _____________________________ Enzyme that unwinds DNA
2. _____________________________ Fragments of copied DNA created on the lagging strand
3. _____________________________ The strand that is copied in a continuous way, from the 3’ to 5’ direction
4. _____________________________ Binds Okazaki fragments
5. _____________________________ Builds a new DNA strand by adding complementary bases
6. _____________________________ Stabilizes the DNA molecule during replication
7. _____________________________ Strand that is copied discontinuously because it is traveling away from helicase
8. _____________________________Initiates the synthesis DNA by creating a short RNA segment at replication fork
9. Place the events in the correct order:
____ DNA polymerase adds nucleotides in the 5’ to 3’ direction
____ Replication fork is formed
____ DNA polymerase attaches to the primer
____ Okazaki fragments are bound together by ligase
____ DNA helicase unwinds DNA
10. Why is replication called “semi-conservative?” ___________________________________________________
www.biologycorner.com | Image Credit: Wikimedia Commons
