Professional Documents
Culture Documents
BENJAMIN E. HIPPEN
To cite this article: BENJAMIN E. HIPPEN (2005) In Defense of a Regulated Market in Kidneys
from Living Vendors , Journal of Medicine and Philosophy, 30:6, 593-626
BENJAMIN E. HIPPEN
A Regulated
Benjamin E. Hippen
Market in Living Vendor Kidneys
I. INTRODUCTION
The current commitment to the principle of equal access to the waiting list
for deceased donor organs is degenerating into an equal opportunity to die
on the waiting list. Though the number of living donors has increased in
response to a growing number of patients in need of kidney transplants,
this response has been and will be inadequate to the current and future
demand. This has spurred interest in novel strategies to increase the number
of available organs, including market solutions.
593
594 Benjamin E. Hippen
But as is often the case, these choices are made in the context of suffering
and tragedy, compounded by the fact that the range of choices available to
donors and recipients are circumscribed by the proscriptions of federal law
(National Organ Transplant Act, 42 USC 273).
If Fox and Swazey’s criticism of donor/recipient relationships is true,
the option of procuring an organ through an organ market actually confirms
a choice of altruistic organ donation as morally salutary in a way that the
current system does not by the application of a strict counterfactual. A
donor who donates even when an organ market offers an alternative source
of organs donates for altruistic reasons, since the alternative source of
organs is irrelevant to the other-regarding feature of the donation. Donors
who refuse to donate when an organ market is available are not motivated
primarily by altruism. Under a market system, the donor’s choice to become
an altruistic donor, with the attendant moral commitments of gift-giving and -
receiving, can be unambiguously interpreted as a courageous, generous act
of supererogation, freely accepted because both the donor and recipient
could have chosen otherwise without the threat of the continued suffering or
untimely death of the recipient. As living donation increasingly becomes the
only plausible route to transplantation, the pressure on potential donors
from the donor’s recipient, family members, or larger moral community is
likely to increase. Most donors will freely renew their moral commitments to
family, community, or faith and donate. For the same reason, donors who
decline to donate because of the alternative of a market in organs perhaps
ought not to be donors in the absence of a market. Donors and their recipi-
ents who choose to accept the burdens (where they exist) of their new rela-
tionship can do so freely, since each had other choices that would still
result in the recipient receiving a transplant.
(Xue, Ma et al., 2001), the needs of all recipients could be met by 0.06% of
the relevant population, assuming that all other living and deceased organ
donation ceased entirely. Even postulating the most rigorous screening cri-
teria for vendors, future demand (driving the cost of organs) would be sub-
stantially offset by the far greater supply of potential organ vendors.
Second, this argument assumes that the only type of valuable consid-
eration available for exchange is personal wealth. However, every U.S. cit-
izen with ESRD who qualifies for Medicare, regardless of their material
wealth, is provided a welfare entitlement to dialysis. Permitting potential
recipients with ESRD to bargain with the state (or simply granting a new
entitlement) in exchange for a transplant would permit a mutually advan-
tageous exchange: longer and improved quality of life for the recipient,
financial benefit to the vendor, and substantial cost-savings to the federal
government.9
Other types of “valuable consideration” might include lifelong health
care insurance coverage (analogous to benefits afforded to veterans), term
life insurance, loan forgiveness programs, scheduled deposits in a tax-shel-
tered retirement account, etc. Alternatively, vendors with less of a need or
interest in personal enrichment can designate a beneficiary, such as a chari-
table or non-governmental organization. Part of a model vendor contract
might include a life/disability benefit in the event of a post-operative catas-
trophe, one that might be extended free of charge to altruistic donors as
well. As a group, appropriately screened kidney donors appear to have the
same long-term outcomes as their age-matched non-donor counterparts. If
vendors were screened as carefully as donors, they would be a comparably
low-risk group to insure.10
Whatever the cost of organs might end up being in a hypothetical mar-
ket in the United States, the potential cost-savings from a functioning trans-
plant compared to dialysis is substantial. As Matas and Schnitzler have
shown (2004), a doubling of the number of organs procured from a market
system would permit Medicare to pay $50,000 per organ and still break
even. As the number of organs procured increases, the break-even price
also increases.
To be sure, the price of organs would change based on a host of fac-
tors, including the quality of organs and small fluctuations in demand and
supply. The enormous supply of potential vendors would ensure that the
price of any one organ would not be dramatically different from any other.
The growing fraction of highly-sensitized patients on the waiting list, most
of whom are almost biologically untransplantable in the current system,
would especially benefit from this arrangement, since the size of the poten-
tial vending pool would markedly improve the chance of finding an immu-
nologically compatible kidney. The flexibility that market relations make
possible permits vendors to accept valuable consideration substantially
600 Benjamin E. Hippen
tailored to their needs. The argument that organs would only be available to
the rich rests on an overly narrow view of market relationships.
follow-up phone call, 22 were eliminated during the initial testing for medi-
cal (fourteen) or psychological (eight) reasons, and two did not complete
the initial testing. Among the medical disqualifiers were: HIV infection, can-
cer, heart disease, morbid obesity, and hypertension. The Minnesota group
has now successfully transplanted kidneys from 22 non-directed donors
with good results, a yield of 6% (22/360) of the initial inquiries.14 As with
blood products, altruistic organ donors are not always the best candidates
for donation. Careful screening overseen by transplant professionals who
are committed to safe practices allows transplant centers to eliminate poten-
tial donors (or vendors) with medical or psychological contraindications.
It might be objected that the profit motive would make screening more
difficult, by creating an incentive on the part of the vendor to lie about condi-
tions that are contraindications to donation.15 However, it is difficult to lie
about objective measurements, such as proteinuria, a positive hepatitis serol-
ogy, or pre-existing conditions such as hypertension. Concerns about fraudu-
lent reporting can be addressed through random and redundant screening
prior to accepting candidates for vending. As the examples of blood product
sales and non-directed donor programs show, it is difficult to support argu-
ments against the efficacy of objective screening methods as applied to organ
vending without applying the same arguments to the screening methods in
altruistic donation. It does not denigrate organ donors to argue that altruistic
donations are not safe just by virtue of being altruistic. It is plausible to
believe that for some potential donors, faced with the suffering and prema-
ture death of a loved one on dialysis, the obligation truthfully to reveal facts
that might disqualify them from donating may be of secondary importance.
And, it is a dangerous conceit to suppose that even the most experienced,
empathetic transplant professionals possess an exhaustive, penetrating insight
into the minds and motives of donors, vendors or recipients. The transplant
community, like the transfusion community, relies on imperfect but highly
effective methods of screening. The approach taken with altruistic donors can
be equally applied to organ vendors: trust, but verify.
It might be argued that a small amount of risk to altruistic donors is
only morally justified because their motives are morally salutary and the
donors (and their doctors) undertake the risks freely. Absent this worthy
motivation, the same risk for the same person as a vendor is not permissi-
ble.16 However, this standard of permissibility renders impermissible a great
many procedures currently deemed morally permissible, if not exactly mor-
ally salutary. For example, the legal licitness of elective liposuction permits
patients and physicians to accept a numerically comparable risk of death
from the procedure.17 If it is true that safe practices ought to be a condition
for the participation of transplant professionals in an organ market, the out-
comes by which the safety of organ vending is judged should be the same
outcomes by which the safety of organ donation is judged. Evidence that an
organ market governed by safe, evidence-based practices resulted in
602 Benjamin E. Hippen
They [Blacks and Hispanics] are being asked to give organs to support a
social and medical system that excludes them and within which they
would have a lower probability of receiving an organ, should that need
A Regulated Market in Living Vendor Kidneys 605
arise. One needs to be relatively affluent and otherwise healthy and well
looked after to be recommended for organ transplant. Widespread
refusal to donate among poor Latino and African Americans is a politi-
cal act of considered resistance (Scheper-Hughes, 2001, p. 66, italics
added).
Is it? Studies of Black American attitudes to organ donation suggest that this
is not the best explanation. Siminoff et al. (2001) has reported less of a will-
ingness to donate a deceased family member’s organ after brain death
among Black Americans compared to Caucasians. However, the differences
between the two groups disappeared when family members knew the
deceased’s wish regarding organ donation (Siminoff & Saunders Sturm,
2000). Siminoff and Saunders Sturm also found that one-quarter of the Black
American respondents had not made up their mind about donating their
organs after death, and some 60 percent of respondents had not discussed
the issue with their family. They conclude, “African Americans’ reliance on
knowing their family member’s wishes may explain their lower rates of con-
sent to donation in actual situations where family members, rather than the
potential organ-donors themselves, become the decision makers” (Siminoff &
Saunders Sturm, 2000, p. 66). Other studies have identified this combination
of family member preconceptions about the wishes of the deceased with
the lack of prior communication regarding the deceased’s actual wishes as a
predictor of unwillingness to donate (Siminoff, Arnold et al., 2001; Haustein
& Sellers, 2004). Haustein and Sellers correlated misconceptions about organ
transplantation more generally with unwillingness to donate. In this survey,
persons less willing to donate were also more likely to believe allocation of
deceased donor organs is based on race and income, that it involves
expense for the donor family, that brain-death implies a chance of recovery,
and that designated organ donors are thereby less likely to receive the care
they need (Haustein and Sellers, 2004). A recent review of deceased kidney
donors in the United States from 1996–2001 revealed a net transfer of 18%
from white donors to black recipients, confirming that the direction of
deceased kidney donation runs in the direction of need rather than in pro-
portion to the ethnicity of the donor (Sehgal, 2004). Misapprehension of
verifiable facts, ambivalence about donation and a lack of communication
with others is unconvincingly described as “a political act of considered
resistance” to the enterprise of transplantation.
Fortunately, arguments alleging the symbolic harm of organ commodi-
fication can be formulated without the conceptual baggage of commodity
fetishism. Arthur Caplan has argued that a market in organs would demon-
strate insensitivity to the legacy of human slavery in the United States by
treating human beings as chattel (Delmonico & Scheper-Hughes, 2003;
Israni, Halpern et al., 2005). This argument is difficult to reconcile with
results of a study Caplan cites in support of this position, which shows that
606 Benjamin E. Hippen
Black Americans are far more favorably disposed to paying families who
agree to donate the organs of their deceased loved ones (43.2% versus
12.9% of Caucasians, p < 0.01 (Siminoff & Saunders Sturm, 2000, p. 68). Of
course, the study in question reviewed attitudes regarding deceased donor
organs, not living organ vending. And, the mere fact that Black Americans
were more disposed to accept compensation does not constitute a justifica-
tion of such practices. However, when Black Americans were actually
asked, the purported symbolic link between compensation and slavery was
not prominent enough to dissuade a substantial number of Black Americans
from approving of compensation in principle.
Speculative assertions of symbolic relationships between organ markets
and slavery are not interchangeable with moral justifications for or against
organ markets. On the contrary, when these equivocations are taken to be
normative, it deprives individual moral agents of the opportunity to fashion
the meaning of such relationships for themselves. The same criticism can be
applied to arguments which relegate certain moral relationships (like altru-
ism) to the prejudices of a “dominant white majority” (Siminoff & Saunders
Sturm, 2000).20 Reducing altruism to a feature of ethnic hegemony cheapens
the moral worth of altruism as practiced by free individuals. On this
account, neither whites nor blacks are truly free to practice altruism; for
whites, altruism becomes merely an extension of ethnic identity, whereas
for blacks it becomes understood as something like acquiescence with
white hegemony. This interpretation of altruism is strikingly different from
how free individuals who choose to act altruistically understand their own
action, and suggests there is something more generally wrong with defend-
ing moral arguments with assertions about speculative symbolic relation-
ships that are either not verifiable (and therefore not subject to dispute) or,
on examination of the evidence, simply not verified.21
When individuals are free to interact with one another, within the con-
straints of moral permissibility, any single relationship might be interpreted
in a variety of ways. Exchanging money for an organ not essential to life
might be viewed as exploitative of the poor or, alternatively, as empower-
ing of a poor person. The burden of justifying restrictions on these interac-
tions shifts from individual moral agents to those who would impede their
free and peaceable interactions with one another, but the standard of proof
includes fulfillment of the necessary conditions for the morally permissible
participation of transplant professionals. Hence, recognizing the fact of
moral pluralism does not entail a defense of moral relativism. Restrictions
remain on how moral agents may permissibly be treated, regardless of one’s
moral commitments, restrictions which I describe as “side-constraints,”22 and
defend in the final section of the paper. In the case of organ markets, such
side-constraints detail the obligation of transplant professionals to limit their
participation in an organ market to situations in which safe, evidence-based
practices can be reasonably assured.
A Regulated Market in Living Vendor Kidneys 607
Dr. Levey and his colleagues are proposing . . . that after various safe-
guards are observed, we permit and even encourage kidney donation
from a stranger to an unknown recipient. I find their proposal objectionable
and unacceptable. Such donations would not be an act of love, and it is
unclear to me what the prospective donor’s motivation would be, if not
financial. Human ingenuity knows no bounds, and in our fortunately
free society it would be exceptionally difficult to be convinced of the
purity of the motives of a “living stranger donor” (Fox & Swazey, 1992,
p. 47).
focusing on the Philippines (Tiong, 2001). The author describes a moral com-
munity which focuses on the centrality of lifelong debts of gratitude to one’s
family (utang na loob), the normative force of authority figures, loyalty to
social units, and profound religious commitment, arguing convincingly that
moral discourse in Philipino culture, to be intelligible, ought to be interpreted
with this context in mind. As an example, Danilo Tiong describes the hypo-
thetical case of an imprisoned Philipino (“Pusakal”) who is offered the oppor-
tunity to discharge obligations to his family by selling a kidney:
Pusakal’s choice takes advantage of the most efficient and effective means
at his disposal, powered with the noble and morally acceptable motive of
love. Absent the kidney sale, there is little likelihood that he could ever
achieve such opportunities for his family. . . . The case is structurally simi-
lar to a case in which Pusakal donates his kidney to another person, who
then agrees to provide for Pusakal’s family. The only difference in this case
is that the purchase is outright, explicit, and honest (Tiong, 2001, p. 92).
disposed to pay heed to it, humility may require that the moral commit-
ments of vendors, like donors, be evaluated on a case-by-case basis. Humil-
ity and a concern for avoiding complicity might well result in judging
cooperation with some vendors permissible, and with some donors imper-
missible, with the result that the currently accepted distinction between
donor and vendor may be morally relevant, but not decisive, in determining
for transplant professionals the moral permissibility of cooperation.
B. Institutional Integrity
Some who view organ vending as permissible will nevertheless also view it as
a morally reprehensible practice. But nothing obligates individual vendors,
donors, recipients, transplant professionals, or transplant centers to participate
in an organ market. Just as some donors will manifest their moral objection to
organ commodification by refusing to accept compensation, some transplant
centers may communicate opposition to all organ markets by refusing to
cooperate with vendors. By fashioning policy on an institutional level, profes-
sionals, vendors, donors and recipients with compatible moral commitments
can cooperate with each other, and, unlike the current system, the forbear-
ance rights of each can be respected in full.
Beyond the other side-constraints, the specific content of different institu-
tional policies might vary widely. Different institutions may alternatively wel-
come, exclude, or maintain a case-by-case policy regarding vendors, internet-
based donor-recipient pairs, non-directed donors, and directed donations to
members within a specific moral community (such as within a religious faith
or ethnic group). Indeed, with enough agreement across individual transplant
centers, few changes need be made to the current system that governs the
allocation of deceased kidneys by privileging waiting time and HLA-matching.
Alternatively, in conjunction with a willing transplant institution, some wait-
listed recipients might choose to bargain with the state, offering Medicare an
opportunity to save the cost of a lifetime dialysis welfare entitlement in exchange
for acting as the purchasing agent for a transplantable kidney and a few
decades of coverage for immuno-suppression medications. In the event a
directed deceased donation is requested that is incompatible with the moral
commitments of one institution, the deceased donor organ might be shipped
to another institution with compatible moral commitments, perhaps in exchange
for an in-kind deceased donor organ transfer in the future.28 The specific con-
tent of individual institutional policies would be of less relevance than the
more general requirement for institutions to formulate policies that articulate
the moral commitments of the institution’s members.
C. Rule of Law
Legislative oversight of an organ market is necessary to ensure that stan-
dards of safety are met, to ensure good-faith enforcement of contracts
614 Benjamin E. Hippen
between vendors and other entities, and to protect against fraud. Ideally,
the law should serve as a side-constraint on other means of assuring institu-
tional integrity, such as accrediting powers of professional organizations
with voluntary membership.
In the context of an organ market, and using a distinction developed
by James Buchanan, the rule of law should have two basic functions
(Buchanan, 2000). First, the rule of law should have a productive function,
which facilitates freely agreed-to arrangements between individuals and
institutions. Second, the rule of law should be designed to protect the con-
tractual and forbearance rights of vendors, donors, recipients, professionals,
and institutions. The productive functions of law include provisions for a
common market in which potential vendors and institutions can meet and
negotiate transactional terms, as well as opportunities for vendors to bargain
with the State regarding the exchange-value of existing welfare entitlements.
The protective functions of the law might include designing sample con-
tracts that satisfy the side-constraints of safety and transparency, offering
adjudication and mediation mechanisms for resolving a range of contractual
disputes, and mediating conflicts of interest such as financial inducements
to increase vending through subversion of safe practices.
I have not offered a specific account of what a regulated organ market
would look like in practice. This is a deliberate omission. The proscriptions
I have argued for are side-constraints, which do not entail a single, specific
account of how an organ market must be structured in order to be consid-
ered morally permissible. These side-constraints are hypothetically compati-
ble with the monopsony model advocated by (among others) Nicholas
Tilney (Radcliffe-Richards et al., 1998) and Arthur Matas (2004) or with more
decentralized market models. On my account, fulfillment of the side con-
straints is a necessary condition for a morally defensible organ market. Of
course, the decision of individuals to be participants in an organ market
would depend on much more than that, namely, the dictates of the moral
commitments of the individuals in question. But, all such interactions ought
to satisfy the side constraints of safety, transparency, institutional integrity,
and operation within the rule of law.
Several problems remain for this view of organ markets, even operating
under the side-constraints previously described.
of grave evil to others. The side-constraints are designed with the assumption
that persons do and will continue to disagree radically over the answers to
substantive moral questions, and proceeds on the assumption that such per-
sons can nevertheless sometimes peacefully cooperate with one another. An
organ market, subject to side-constraints, is of instrumental value in the
peaceable mediation of these profound moral differences.
for the same reason. Even if the lack of a robust deceased donor procure-
ment program is not conspiratorial, the lack of a deceased donor program
that results in an increase in demand for organs from living vendors is a sys-
tem which benefits organ traffickers.
A market in organs from living vendors poses further problems. Since
the vendor is selling an organ while alive, an organ qua commodity could
also be viewed as a valuable asset by third parties who have other financial
relationships with vendors. Throughout, I have argued that vendors might
choose to sell their organs for a wide variety of reasons, including the
repayment of accumulated debt. If this is permissible, and absent other
means of payment, may a creditor require the sale of an organ (for living
vendors, or after death) for the purpose of debt repayment? If an organ qua
property is part of the estate of a living or deceased vendor, this question
tests the limits of viewing a vendor’s “right to vend” as a forbearance right.
If it is permissible to allow vendors to sell their organs and use the exchange
to further their own ends, it seems arbitrary to prohibit third parties from
insisting that vendors fulfill a financial obligation by selling a kidney. Nor
does this scenario necessarily violate Epstein’s (1995) caveat regarding con-
tracts that do not mutually benefit both parties, since paying off a debt is
arguably a benefit to the debtor.
However, it does not follow that such exchanges (or such contracts) are
therefore defensible. When, in The Merchant of Venice, Shylock demands a
pound of flesh as payment for a broken contract, Portia (disguised as a
judge) pronounces that the extraction of this gruesome restitution is indeed
part of a legally valid contract. But, Portia qualifies a crucial difference
between what the law permits, and what justice demands.30 Portia’s admo-
nition is a reminder that the side-constraints previously discussed do not
only apply to health care providers and institutions. To treat the side-
constraints as merely pro forma conditions for permissible action is to fail to
accord individuals the respect required by their moral agency. Persistent or
systematic violations of respect for moral agency may require that the con-
tent of the side-constraints be revisited and revised accordingly.
NOTES
1. The arguments in this paper represent the views of the author alone, and do not represent the
policies or opinions of the UNOS ethics committee, nor the Carolinas Medical Center or any department,
division or other employee thereof. The author does not condone the violation of any existing state or
federal law governing transplantation in the United States or elsewhere.
2. In 2002, 6,233 persons were living kidney donors, of which 1,789 (28.7%) were from a spouse
or other biologically unrelated persons. From http://www.ustransplant.org, Table 2.9.
3. As many as 30% of patients on the waiting list for a deceased donor kidney have circulating
antibodies specific for antigens found on renal allografts from human beings. The presence of these anti-
bodies can result in an accelerated rejection of the allograft after transplantation, and can be identified
by a test called a crossmatch. A recipient’s sera may have antibodies against a wide array of antigens
identified in humans, identified by testing against a “panel” of known antigens. The practical conse-
quence for recipients of having such antibodies is that it can make finding a compatible organ much
more difficult, since the donor kidney would need to be both of compatible blood type and not express
antigens against which the recipient has antibodies.
620 Benjamin E. Hippen
4. In 2002, 68,468 patients were listed for a deceased donor kidney transplant, and 3,396 died on
the waiting list (4.9%). From http://www.ustransplant.org, Table 1.7.
5. The choice to donate or not to donate an organ often occurs in the context of observing a
recipient’s progressive illness and consequent suffering. This context is not neutral with regard to donor
motivation. Even if the suffering of recipients does not generate prima facie moral obligations on the
part of donors, the experience of a recipient’s suffering can impact the moral psychology of donor moti-
vation in variable ways. As Elaine Fox and Judith Swazey have shown (Fox & Swazey, 1992), a decision
to donate made in the context of the recipient’s suffering does not ensure that altruistic motives for
donation are paramount.
6. The process of screening organ donors operates on the premise that organ donation is super-
erogatory, rather than merely obligatory. Most every transplant center emphasizes to the donor that they
are not obligated to donate, that participation in the donor screening process in no way obligates them
to proceed with donation, and that the donor can withdraw their consent to donate for any reason, at
any time, and with assurances that the reasons for this decision will not be communicated to anyone. It
is implausible that such safeguards would exist to ensure that donors would be free to refuse a moral
obligation.
7. Note that a reduction in donations in response to an organ market does not imply a reduction
in the number of available organs for transplantation, just a reduction in the number of donated organs.
8. As Tibor Machan explains, “[State-imposed restriction] deprives the person who is the target of
such restrictions or constraints from being able to take charge of his or her conduct, to direct himself or
herself in life, thus robbing the person of the opportunity to earn moral credit, to become morally better
(or worse)“ (1997, p. 249).
9. Yen et al. (2004) calculated that costs to Medicare for a renal transplant and immunosuppression
over 20 years was $311,473, compared to $530,746 for a dialysis patient with a 10-year median life span.
10. In addition, a program providing health care coverage to persons in exchange for donating a
kidney could also serve a dual purpose as an ongoing registry, where the long-term health effects of
donation could be studied in a detail previously not available to researchers.
11. Starr concludes: “But, in examining the tainted-blood tragedies of the 1980s, it becomes clear
that no system was immune from mistakes, whether capitalist or socialist, monolithic or decentralized.
Countries that emerged from the crisis with relatively low blood borne disease rates had a few simple,
common elements: diligent people in charge who fostered rapid response, open communications, and
close control over the source of their supplies. Safety is a matter of practice, not ideology“ (italics added)
(1998, p. 355).
12. As Joel Schwartz observes, “All together, collection facilities pay plasma donors well over
$200 million each year. The plasma-products industry, facilitated by these transactions, generates more
than $4 billion in revenues worldwide. American firms are responsible for more than 60% of these sales.
America exports plasma and plasma products to 80% of the world’s nations.” (1999)
13. 3.1 per 1,000 donations from volunteers deferred compared to 0.7 per 1,000 from paid
“donors”, p < 0.001. (Simon, 1998; Strauss, 2001) An important difference between organ vending and
plasma vending is the fact that plasma vendors are frequent vendors. The safety of the products sold by
plasma vendors is ensured through multiple, repeated screenings. Analogous effective safeguards in
screening organ vendors would need to be identified and adopted for the analogy to withstand scrutiny.
14. Gilbert et al. (2005) reported similar attrition, for similar reasons, in Washington, D.C.; how-
ever seven of their potential donors were found to be active substance abusers.
15. I deal with the companion concern, that the profit motive would cause an insoluble conflict of
interest for the transplant center, in the final section.
16. The fact that harvesting a kidney entails some physical risk does not provide sufficient reason
to prohibit an organ market, since the objection applies equally to living organ donation. But, the
known risks of living kidney donation (Ellison et al., 2002; Matas et al., 2003) can serve as a standard by
which vendor safety can be compared.
17. The risk of post-operative death from a lipoplasty procedure was recently reported to be 95/
496,245 or 0.019%. (Grazer & de Jong, 2000)
18. Even when safe practices are able to be reasonably guaranteed, transplant centers and trans-
plant professionals would still be free not to accept organs from vendors. Objections to some or all
organ vending is entirely consistent with understanding the right to donate (or to be a vendor) as a for-
bearance right (Cherry, 2000). Concerns regarding a potential tort on the part of an organ vendor against
a transplant center fall outside vendor’s forbearance right to donate, and the correlative obligation of
A Regulated Market in Living Vendor Kidneys 621
non-interference on the part of transplant professionals, and are therefore unfounded. Also, acting on
disapproval of organ vending need not be limited to transplant professionals. Just as some recipients
might find centers that assure them a transplant in the near future more attractive, some donors and
recipients with principled objections to organ vending might prefer to receive their operations and sub-
sequent care at centers that share these moral commitments.
19. Commodity fetishism describes a subversion of proper human activity and social relationships
by changing the concepts by which these activities and relations are understood into the language and
concepts of commodities, which in turn are governed by market forces rather than by moral agents
(Radin, 1996, p. 81).
20. “The current U.S. organ procurement system is based upon values that reflect the attitudes and
beliefs of the dominant white majority. The primary moral basis of this system is altruism” (Siminoff &
Saunders Sturm, 2000, p. 68). This provocative conclusion, (while false), does demonstrate that sweep-
ing generalizations regarding social perceptions of organ markets are frequently unfounded.
21. Discussing the importance of the symbolic relationship of offering tokens of thanks rather
than compensation to donors, Delmonico and Scheper-Hughes argue that symbols are “figurative
representations of core social values and boundaries [that are] both subtle and complex, and do not
always stand up to rational analysis” (Delmonico et al., 2002, p. 2004). Nonetheless, the authority of
asserted symbolic value over the product of autonomous decision-making is apparently justified if “. . .
it can be shown that the social fabric of society would be threatened or weakened” (Delmonico and
Scheper-Hughes, 2003, p. 694). The reason this argument doesn’t stand up to rational analysis is
because there is no single set of “core social values” that bridges the deep moral disagreements
which are the hallmark of moral pluralism in contemporary secular societies (Engelhardt, 1996;
Engelhardt, 2004). Judgments about the “weakness” or “strength” of the “social fabric” are transpar-
ently circular, depending entirely on the content of the various moral commitments of persons who
make up society. Attempts to identify normative symbols of “core social values” that trump the moral
commitments of rational individuals are inevitably shown to be ciphers for specific moral commit-
ments over which there is profound disagreement between such individuals (Engelhardt, 1996).
Fashioning public policy in an attempt to paper over these disagreements with appeals to “societal
norms” subordinates moral pluralism to political power, obscuring in practice the distinction between
power and authority.
22. The term “side-constraints” is a widely recognized term coined by Robert Nozick (1975).
23. For example, Vivekanand Jha (2004) plausibly argues that such a system is not currently possi-
ble in India, due to widespread corruption and lack of legal protection for vendors, but might be permis-
sible in countries where such protections could plausibly be enacted and enforced.
24. This contrasts with the reluctant defense of a market in organs by Veatch (2003), who
sanguinely argues that a society that conspicuously fails to provide for its worst-off citizens might as
well permit them to sell their organs. As with the critics of organ markets, Veatch assumes that
organ vending would always be an act of desperation, a view which inadequately explains Pusakal’s
situation.
25. Humility is not quietism. Rather, humility with regard to evaluating the moral commitments
of others should entail a reconsideration of the burden and standards of proof as to what constitutes
morally permissible actions, and does not entail that no such standards exist. Thus, for example, invol-
untary female circumcision may properly be judged a grave moral violation, regardless of the coher-
ence of the practice with other moral/cultural commitments of a culture. There is a legitimate question
as to why such a judgment is not merely circular or unjustifiably ethnocentric. While the burden of
proof regarding the moral wrongness of cultural practices may lie with the accuser, a cross-cultural
standard of proof includes the assumption that while persons in all cultures may be influenced by
moral commitments arising from cultural norms, persons are not exhaustively defined by cultural
norms. Thus, the judgment that involuntary female circumcision is a grave moral wrong begins with
the observation that it is involuntary, an implicit recognition that persons possessed of reason, instan-
tiated within a set of cultural commitments, can nevertheless peaceably dissent from those commit-
ments, and ought to be able to do so without fear of physical violation. As I have argued above, while
the fact of difference (and therefore dissent) does not have normative significance in and of itself, the
moral authority to suppress difference (and therefore dissent) is quite limited. However, within the
limits of protection is the ability of dissenters to peaceably dissent without subjection to physical harm
by a moral community. I concede that the cultural/psychological harms of ostracism are also harms,
which in turn may lead to physical harms (such as destitution) but confess that the narrow moral
622 Benjamin E. Hippen
authority I am committed to does not justify intervention by the state to resolve these problems. Indi-
viduals, on the other hand, may be obligated by their own particular moral commitments to assist
where the state lacks authority to do so. Alternatively, individuals may also be obliged not to partici-
pate in transactions judged to be grave moral wrongs.
26. Long-term follow-up data from participants in organ trafficking is difficult, since most return to
their country of origin, and none have any interest in admitting their participation in illegal activity.
Organ traffickers have little incentive to publish outcomes data, since their activities are subject to legal
and professional sanction. Good outcomes will not reduce the legal and professional risks of their enter-
prise, and advertising poor outcomes can only serve to increase such risks and possibly reduce patron-
age. Though there is disagreement in the literature on this point, a review of small studies from a variety
of countries suggest that on the whole, recipients’ outcomes from paid vendors are worse compared to
transplants from living related donors. See (Reddy et al., 1990; Thiagarajan et al., 1990) for examples of
positive results and compare with (Chugh, 1996; Ivanovski et al., 1997; Lawrence, 1997; Chugh and Jha,
2000; Goyal et al., 2002; Higgins et al., 2003; Jha, 2004). This outcome is not country-specific. (Sever
et al., 2001).
27. As Richard Epstein argues, “The case in favor of freedom rests on the postulate of mutual gains
through trade. The rationale for the institution provides the essential clue for its limitation. When bar-
gaining takes place in settings where mutual gain is not the probable outcome, there is sufficient warrant
for the law to step in and set that transaction aside” (Epstein, 1995, p. 80).
28. Institutions with a policy of refusing to cooperate with all organ vendors would face derivative
problems of moral complicity with organ vending. If an organ market were to substantially increase the
number of available organs for transplantation, and the rates of altruistic living donation and deceased
donation did not drop substantially, the result would be that fewer recipients on the deceased donor
waiting list would compete for a similar number of deceased donor organs, increasing the rate of trans-
plantation while on the waiting list. Thus, institutions that did not directly participate in organ vending
might derive “free-rider” benefits from the shortened waiting list. Conversely, if an organ market resulted
in a marked decrease in the number of altruistic living donors and deceased donors, recipients at that
institution might either be more disadvantaged by virtue of competing for even fewer organs, or decide
to pursue organ vending opportunities at another institution. In this situation, the institution may not be
complicit in organ vending, but the recipients wait-listed at that institution might be disadvantaged by
the institution’s policy of non-participation. This disadvantage might not matter if the moral commit-
ments of the disadvantaged recipients are nevertheless reflected by the institution’s policy of non-
cooperation with vendors.
29. Eventually, this caution would need to be either supported or refuted by evidence. It should
be emphasized that the side-constraints I argue for would require any study of the safety of organ vend-
ing in other countries to report outcomes data on both vendors and recipients.
30. PORTIA.
Tarry a little; there is something else.
This bond doth give thee here no jot of blood;
The words expressly are ‘a pound of flesh’:
Take then thy bond, take thou thy pound of flesh;
But, in the cutting it, if thou dost shed
One drop of Christian blood, thy lands and goods
Are, by the laws of Venice, confiscate
Unto the state of Venice.
GRATIANO. O upright judge! Mark, Jew: O learned judge!
SHYLOCK. Is that the law?
PORTIA.
Thyself shalt see the act;
For, as thou urgest justice, be assur’d
Thou shalt have justice, more than thou desir’st.
The Merchant of Venice, Act IV, i (Shakespeare, 1974).
31. I am grateful for discussions of issues related to this paper with Lisa Rasmussen, Maureen
Kelley, Robert S. Gaston, Mark Deierhoi, Francis Delmonico, Lance Stell and Gregory Pence. I am espe-
cially indebted to the intellectual labors in this area of Mark Cherry, and more generally to the mentor-
ship and friendship over the years of H. Tristram Engelhardt, Jr. The responsibility for all errors of fact,
judgment, or reasoning rest with the author.
A Regulated Market in Living Vendor Kidneys 623
REFERENCES
Gilbert, J.C., Brigham, L., & et al. (2005). The nondirected living donor program: a
model for cooperative donation, recovery and allocation of living donor kid-
neys. American Journal of Transplantation, 5(1), 167–174.
Gossmann, J., Wilhelm, A., & et al. (2005). Long-term consequences of live kidney
donation follow-up in 93% of living kidney donors in a single transplant cen-
ter. American Journal of Transplantation, 5(10), 2417–2424.
Goyal, M., Mehta, R.L., & et al. (2002). Economic and health consequences of sell-
ing a kidney in India. Journal of the American Medical Association, 288(13),
1589–1593.
Grazer, F.M., & de Jong, R.H. (2000). Fatal outcomes from liposuction: census sur-
vey of cosmetic surgeons. Plastic and Reconstructive Surgery, 105(1), 436–46
discussion 447–448.
Haustein, S.V., & Sellers, M.T. (2004). Factors associated with (un)willingness to be
an organ donor: importance of public exposure and knowledge. Clinical
Transplantation, 18(2), 193–200.
Higgins, R., West, N., & et al. (2003). Kidney transplantation in patients travelling
from the UK to India or Pakistan. Nephrology, Dialysis, Transplantation, 18(4),
851–852.
Israni, A.K., Halpern, S.D., & et al. (2005). Incentive models to increase living kid-
ney donation: encouraging without coercing. American Journal of Transplan-
tation, 5(1), 15–20.
Ivanovski, N., Stojkovski, L., & et al. (1997). Renal transplantation from paid, unre-
lated donors in India – it is not only unethical, it is also medically unsafe.
Nephrology, Dialysis, Transplantation, 12(9), 2028–2029.
Jacobs, C.L., Roman, D., & et al. (2004). Twenty-two nondirected kidney donors:
an update on a single center’s experience. American Journal of Transplanta-
tion, 4(7), 1110–1116.
Jha, V. (2004). Paid transplants in India: the grim reality. Nephrology, Dialysis,
Transplantation, 19(3), 541–543.
Kahn, J.P., & Delmonico, F.L. (2004). The consequences of public policy to buy and
sell organs for transplantation. American Journal of Transplantation, 4(2),
178–180.
Kasiske, B.L., Cangro, C.B., & et al. (2002). The evaluation of renal transplantation
candidates: clinical practice guidelines. American Journal of Transplantion,
1(Suppl 2), 1–95.
Lawrence, R. (1997). Abuse of live related kidney transplantation. Nephrology,
Dialysis, Transplantation, 12(9), 2028.
Lee, Y.H., Huang, W.C., & et al. (1994). The long-term stone recurrence rate and
renal function change in unilateral nephrectomy urolithiasis patients. The Jour-
nal of Urology, 152(5 Pt 1), 1386–1388.
Machan, T.R. (1997). Blocked exchanges revisited. Journal of Applied Philosophy,
14(3), 249–262.
Matas, A.J. (2004). The case for living kidney sales: rationale, objections and con-
cerns. American Journal of Transplantation, 4(12), 2007–2017.
Matas, A.J., Bartlett, S.T., & et al. (2003). Morbidity and mortality after living kidney
donation, 1999–2001: survey of United States transplant centers. American
Journal of Transplantation, 3(7), 830–834.
A Regulated Market in Living Vendor Kidneys 625
Matas, A.J., & Schnitzler, M. (2004). Payment for living donor (vendor) kidneys:
a cost-effectiveness analysis. American Journal of Transplantation, 4(2),
216–221.
Meier-Kriesche, H.U., & Kaplan, B. (2002). Waiting time on dialysis as the strongest
modifiable risk factor for renal transplant outcomes: a paired donor kidney
analysis. Transplantation, 74(10), 1377–1381.
Nozick, R. (1975). Anarchy, state, and utopia. Oxford: Blackwell.
Ojo, A.O., Hanson, J.A., & et al. (2001). Survival in recipients of marginal cadaveric
donor kidneys compared with other recipients and wait-listed transplant candi-
dates. Journal of the American Society for Nephrology, 12(3), 589–597.
Oniscu, G.C., Brown, H., & et al. (2004). How old is old for transplantation?. American
Journal of Transplantation, 4(12), 2067–2074.
Pence, G. (2002, April 9). Organ donors risk health. Los Angeles Times, B13.
Prottas, J.M. (1992). Buying human organs – evidence that money doesn’t change
everything. Transplantation, 53(6), 1371–1373.
Radcliffe-Richards, J., Daar, A.S., Guttman, R.D., Hoffenberg, R., Kennedy, I., Lock, M.,
Sells, R.A., & Tilney, N. (1998). The case for allowing kidney sales. Lancet, 351,
1950–1952.
Radin, M.J. (1996). Contested commodities. Cambridge: Harvard University Press.
Reddy, K.C., Thiagarajan, C.M., & et al. (1990). Unconventional renal transplanta-
tion in India. Transplantation Proceedings, 22(3), 910–911.
Scheper-Hughes, N. (2000). The global traffic in human organs. Current Anthropol-
ogy, 41(2), 191–224.
Scheper-Hughes, N. (2001). Commodity fetishism in organs trafficking. Body Soci-
ety, 7(2–3), 31–62.
Scheper-Hughes, N. (2002). The ends of the body: Commodity fetishism and the
global traffic in organs. SAIS Review, XXII(1), 61–80.
Schwartz, J. (1999). Blood and altruism—Richard M. Titmuss’ criticism on the com-
mercialization of blood. Public Interest, 136 (Summer, 1999).
Sehgal, A.R. (2004). The net transfer of transplant organs across race, sex, age, and
income. The American Journal of Medicine, 117(9), 670–675.
Sever, M.S., Kazancioglu, R., & et al. (2001). Outcome of living unrelated (commer-
cial) renal transplantation. Kidney International, 60(4), 1477–1483.
Shakespeare, W. (1974). The Riverside Shakespeare. Boston: Houghton Mifflin Company.
Siminoff, L.A., Arnold, R.M., & et al. (2001). The process of organ donation and its
effect on consent. Clinical Transplantation, 15(1), 39–47.
Siminoff, L.A., & Saunders Sturm, C.M. (2000). African-American reluctance to
donate: beliefs and attitudes about organ donation and implications for policy.
Kennedy Institute for Ethics Journal, 10(1), 59–74.
Simon, T.L. (1998). Monetary compensation for plasma donors: a record of safety.
Transfusion, 38(9), 883–886.
Sonnenday, C.J., Warren, D.S., & et al. (2004). Plasmapheresis, CMV hyperimmune
globulin, and anti-CD20 allow ABO-incompatible renal transplantation without
splenectomy. American Journal of Transplantation, 4(8), 1315–1322.
Starr, D.P. (1998). Blood: An epic history of medicine and commerce. New York:
Alfred A. Knopf.
Strauss, R.G. (2001). Blood donations, safety, and incentives. Transfusion, 41(2), 165–167.
626 Benjamin E. Hippen
Surman, O.S., Fukunishi, I., Allen, T., & Hertl, M. (2005). Live organ donation:
Social context, clinical encounter, and the psychology of communication. Psy-
chosomatics, 46(1), 1–6.
Textor, S.C., Taler, S.J., & et al. (2003). Blood pressure evaluation among older liv-
ing kidney donors. The Journal of the American Society for Nephrology, 14(8),
2159–2167.
Thiagarajan, C.M., Reddy, K.C., & et al. (1990). The practice of unconventional
renal transplantation (UCRT) at a single centre in India. Transplantation Pro-
ceedings, 22(3), 912–914.
Tiong, D.C. (2001). Human organ transplants. In A. Tan-Alora & J.M. Lumitao (eds.),
Beyond a western bioethics: Voices from the developing world. Washington, DC:
Georgetown University Press.
Titmuss, R.M. (1970). The gift relationship: From human blood to social policy.
London: Allen & Unwin.
Tyden, G., Kumlien, G., & et al. (2003). Successful ABO-incompatible kidney trans-
plantations without splenectomy using antigen-specific immunoadsorption and
rituximab. Transplantation, 76(4), 730–731.
Veatch, R.M. (2003). Why liberals should accept financial incentives for organ pro-
curement. Kennedy Institute for Ethics Journal, 13(1), 19–36.
Warren, D.S., Zachary, A.A., & et al. (2004). Successful renal transplantation across
simultaneous ABO incompatible and positive crossmatch barriers. American
Journal of Transplantation, 4(4), 561–568.
Xue, J.L., Ma, J.Z., & et al. (2001). Forecast of the number of patients with end-
stage renal disease in the United States to the year 2010. The Journal of the
American Society for Nephrology, 12(12), 2753–2758.
Yen, E.F., Hardinger, K., & et al. (2004). Cost-effectiveness of extending Medicare
coverage of immunosuppressive medications to the life of a kidney transplant.
American Journal of Transplantation, 4(10), 1703–1708.
Zargooshi, J. (2001). Quality of life of Iranian kidney “donors”. The Journal of Urol-
ogy, 166(5), 1790–1799.