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It was also Heraclitus who defined this entity with his term "Logos" or 'rational
principle'. He writes:
**"Heraclitus somewhere says that all things are in process and nothing
stays still, and likening existing things to the stream of a river he says
that you would not step twice into the same river."
In this citation Heraclitus articulates one of the most important problem of philosophy
and of science: As everything is in the process of change, how can one know anything
for certain? The statement is the foundation of 'epistemology', the study of knowledge.
The most recent and significant formulation of the problem is the Heisenberg
Principle (devised by the Nobel prize winning physicist of the 1930s).
Pythagoras and his followers perceived that the ultimate reality (arché) was not
something material, but number (we might translate that to mean that any natural
phenomenon might be described mathematically).
"Ten is the very nature of number. All Greeks and all barbarians alike
count up to ten, and having reached ten, revert again to the unit. And
again,