Professional Documents
Culture Documents
Referencias Introducción
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Mercenne G, Bernacchi S, Richer D, Bec G, Henriet S, Paillart JC, Marquet R. HIV-1 Vif binds
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Briggs JA, Simon MN, Gross I Kräusslich HG, Fuller SD, Vogt VM, Johnson MC. The
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Wei P, Garber ME, Fang SM, Fischer WH, Jones KA. A novel CDK9-associated C-type cyclin
interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to
TAR RNA. Cell 1998, 92(4): 451-62.
Yang OO, Nguyen PT, Kalams SA, Dorfman T, Gottlinger HG, Stewart S, et al. Nef-mediated
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Collins KL, Chen BK, Kalams SA, Walker BD, Baltimore D. HIV-1 Nef protein protects
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Ferguson MR, Rojo DR, von Lindern JJ, O'Brien WA. HIV-1 replication cycle. Clin Lab Med
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Turner BG, Summers MF. Structural biology of HIV. J Mol Biol 1999, 285(1): 1-32.
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Henderson BR, Percipalle P. interactions between HIV Rev and nuclear import and export
factors: the Rev nuclear localization signal mediates specific binding to human importin-
beta. J Mol Biol 1997, 274: 693-707.
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Mehle A, Strack B, Ancuta P, Zhang C, McPike M, Gabuzda D. Vif overcomes the innate
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Keegan LP, Gallo A, O’Connell MA. 2001. The many roles of an RNA editor. Nature Rev.
Genet. 2, 869-878.
Eckmann CR, Neunteufl A, Pfaffstetter L, Jantsch MF. 2001. The human but not the Xenopus
RNA-editing enzyme ADAR1 has an typical nuclear localization signal and displays the
characteristics of a shuttling protein. Mol. Biol. Cell 12, 1911-1924.
Brownawell AM, Macara IG. 2002. Exportin-5, a novel karyopherin, mediates nuclear export
of double-stranded RNA binding proteins. J. Cell Biol. 156, 53-64.
Patel CV; Handy I, Goldsmith T, Patel RC. 2000. PACT, a stress-modulated cellular activator
of interferon-induced double stramded RNA-activated protein kinase, PKR. J. Biol. Chem.
275, 37993-37998.
Reichman TW, Parrot AM, Fierro-Monti I, Caron DJ, Kao PN, Lee CG, Li H, Mathews MB. 2003.
Selective regulation of gene expression by nuclear factor 110, a member of the NF90
family of double stranded RNA-binding proteins. J. Mol. Biol. 332, 85-98.
Larcher JC, Gasmi, L, Viranaichen W, Eddé B, Bernard R, Ginzburg I, Denoulet P. 2004. Ilf3
and NF90 associate with the axonal tAeting element of Tau mRNA. Faceb 14, 1761-1763.
Parrot AM, Walsh MR, Reichman TW, Mathews MB. 2005. RNA binding and phosphorylation
determine the intracellular distribution of nuclear factor 90 and 110. J. Mol. Biol. 348, 281-
923.
Kao PN, Chen L, Brock G, Ng J, Kenny J, Smith AJ, Corthésy B. 1994. Cloning and
expression of cyclosporine A- and FK506-sensitive nuclear factor of activated T-cells:
NF45 and NF90. J. Biol. Chem. 269, 20691-20699.
Patel RC, Vestal DJ, Xu Z, Bandyopadhyay S, Guo W, Erme SM, Williams BR, Sen GC. 1999.
DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the
interferon-induces protein kinase, PKR. J. Biol. Chem. 274, 20432-20437.
Saunders LR, Jurecic V, Barber GN. 2000. The 90- and 110- kDa Human NFAR proteins are
translated from two differentially spliced mRNA encoded on chromosome 19p13.
Genomics. 71, 256-259.
Langland JO, Kao PN, Jacobs BL. 1999. Nuclear factor-90 of activated T-cell: a double-
stranded RNA-binding protein and substrate for the double –stranded RNA-dependent
protein kinase, PKR. Biochemistry. 38, 6361-6368.
Parrot AM, Walsh MR, Reichman TW, Mathews. 2005. RNA binding and phosphorylation
determine the intracellular distribution of nuclear factor 90 and 110. J. Mo. Biol. 348, 281-
293.
Pei Y, Zhu P, Dang Y, Wu J, Yang X, Wan B, Liu JO, Yi Q, Yu L. 2008. Nuclear export of
NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at ser647 in
response to CD28 costimulation. J. Immunol. 180, 222-229.
Referencias Materiales y Metodos
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Fouchier RA, Meyer BE, Simon JH, Fischer U, Malim MH. HIV-1 infection of non-dividing
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Taborda NA, Acevedo LY, Patino CP, Forero JE, López-Herrera A. Actividad antiviral in vitro
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Tiedemann RE, Zhu YX, Schmidt J, Yin H, Shi CX, Que Q, Basu G, Azorsa D, Perkins LM,
Braggio E, Fonseca R, Bergsagel PL, Mousses S, Stewart AK. Kinome-wide RNAi studies in
human multiple myeloma identify vulnerable kinase tAets, including a lymphoid
restricted kinase, GRK6. Blood. 2010, 115: 1594-1604.
Referencias Resultados
Parrot AM, Walsh MR, Reichman TW, Mathews MB. RNA binding and phosphorylation
determine the intracellular distribution of nuclear factor 90 and 110. J. Mol. Biol. 2005,
348: 281-923.
Keegan LP, Gallo A, O’Connell MA. 2001. The many roles of an RNA editor. Nature Rev.
Genet. 2001, 2: 869-878.
Parker LM, Fierro-Monti I, Mathews MB. Nuclear factor 90 is a substrate and regulator of the
eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinase. J Biol
Chem. 2001, 35: 32522-32530
Henderson BR, Percipalle P. interactions between HIV Rev and nuclear import and export
factors: the Rev nuclear localization signal mediates specific binding to human importin-
beta. J Mol Biol 1997, 274: 693-707.
Doyle M, Jantsch MF.. New and old roles of the doublé-stranded RNA- binding domain. J.
Struc. Biol. 2003, 140: 147-153.
Kao PN, Chen L, Brock G, Ng J, Kenny J, Smith AJ, Corthésy B. Cloning and expression of
cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90. J
Biol Chem. 1994, 32: 20691-20699.
Eckmann CR, Neunteufl A, Pfaffstetter L, Jantsch MF. The human but not the Xenopus RNA-
editing enzyme ADAR1 has an typical nuclear localization signal and displays the
characteristics of a shuttling protein. Mol. Biol. Cell. 2001, 12: 1911-1924.
Brownawell AM, Macara IG. 2002. Exportin-5, a novel karyopherin, mediates nuclear export
of double-stranded RNA binding proteins. J. Cell Biol. 2002, 156: 53-64.
Shi L, Godfrey WR, Lin J, Zhao G, Kao PN. NF90 regulates inducible IL-2 gene expression
in T cells. J Exp Med. 2007, 5: 971-977.
Pei Y, Zhu P, Dang Y, Wu J, Yang X, Wan B, Liu JO, Yi Q, Yu L. Nuclear export of NF90 to
stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in
response to CD28 costimulation. J Immunol. 2008, 1: 222-229.
Zhu P, Jiang W, Cao L, Yu W, Pei Y, Yang X, Wan B, Liu JO, Yi Q, Yu L. IL-2 mRNA
stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by
protein kinase. J Immunol. 2010, 9: 5140-5149.
Briggs JA, Simon MN, Gross I Kräusslich HG, Fuller SD, Vogt VM, Johnson MC. The
stoichiometry of Gag protein in HIV-1. Nat Struct Mol, Biol. 2004, 11: 672-675.
Shin HJ, Kim SS, Cho YH, Lee SG, Rho HM. Host cell proteins binding to the encapsidation
signal epsilon in hepatitis B virus RNA. Arch Virol. 2002, 3: 471-491.
Wang P, Song W, Mok BW, Zhao P, Qin K, Lai A, Smith GJ, Zhang J, Lin T, Guan Y, Chen H.
Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral
nucleoprotein. J Virol. 2009, 16: 7850-7861.
Agbottah ET, Traviss C, McArdle J, Karki S, St Laurent GC 3rd, Kumar A. Nuclear Factor
90(NF90) tAeted to TAR RNA inhibits transcriptional activation of HIV-1. Retrovirology.
2007, 12: 4:41.