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Dihybrid Inheritance

Dihybrid inheritance refers to


the simultaneous inheritance
of two characters
Mendel’s experiment
 Mendel investigated the inheritance of
seed shape (round v wrinkled) and seed
colour (green v yellow) at the same time.
 From his monohybrid crosses he knew that
round seeds were dominant to wrinkled
seeds and yellow seeds were dominant to
green seeds.
 He chose to cross plants that were pure
breeding for both dominant features
(round and yellow seeds) with plants that
were pure breeding for both recessive
features (wrinkled and green seeds)
Results
Parents plants with round x plants with wrinkled
and yellow seeds and green seeds

F1 offspring 100% plants with round and yellow seeds

F1 intercross plants with round x plants with round


and yellow seeds and yellow seeds
F2 offspring Total 556 seeds collected from F2 plants

Ratio
315 9 round and yellow seeds
108 3 round and green seeds
101 3 wrinkled and yellow seeds
32 1 wrinkled and green seeds

However, the ratio of dominant to recessive features


is still 3:1
Explanation of Mendel’s results
 Let the allele for round seeds be R and the
allele for wrinkled seeds be r
 Let the allele for yellow seeds be Y and the
allele for green seeds be y

Parents Phenotype round x wrinkled


yellow seeds green seeds
Genotype RR YY rryy

Gametes RY RY ry ry

F1 offspring
gametes
gametes RY RY
ry RrYy RrYy
ry RrYy RrYy
F1 intercross

Parents

phenotype round, yellow seeds x round, yellow seeds


genotype Rr Yy Rr Yy

Gametes RY Ry rY ry RY Ry rY ry

What are the genotypes and phenotypes of the F2


offspring and in what ratio?
F2 offspring
gametes
gametes RY Ry rY ry
RY RRYY RRYy RrYY RrYy
Ry RRYy RRyy RrYy Rryy
rY RrYY RrYy rrYY rrYy
ry RrYy Rryy rrYy rryy

genotypes phenotypes expected observed

RRYY (1) RrYy (4) yellow, round


RRYy (2) RrYY (2) yellow, round 9 315
RRyy (1) Rryy (2) round, green 3 108
rrYY (1) rrYy (2) wrinkled, yellow 3 101
rryy (1) wrinkled, green 1 32
 Allowing for statistical error, Mendel’s results
were a reasonable approximation to the
expected 9:3:3:1 ratio
 Each of a member of an allelic pair may
combine randomly with either of another pair
 A test cross can be performed to check the
possible genotypes of a plant producing round,
yellow seeds (RRYY, RrYY, RrYy, RRYy) by
crossing the plants with a homozygous
recessive plant with wrinkled green seeds
genotype rryy

 What phenotypes and genotypes would


the offspring possess from the 4 crosses,
and in what ratios?

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