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Klinghardt
Reihe: Entgiftung
Teil I: Glyphosat
Juli 2020
What is glyphosate?
H
Glycine - Glyphosate
GLYCINES
*A Samsel and S Seneff. Entropy 2013; 15: 1416-1463.
**K Syed and SS Mashele. PLOS ONE 2014; 9(4):| e95616.
Entgiftung Teil I: Glyphosat
Scientific Research Vol.6 No.1, January 2015 PP. 42-70
Aluminum and Glyphosate Can Synergistically Induce Pineal Gland Pathology: Connection to Gut
Dysbiosis and Neurological Disease
Stephanie Seneff, Nancy Swanson, Chen Li
ABSTRACT
Many neurological diseases, including autism, depression, dementia, anxiety disorder and Parkinson’s disease, are
associated with abnormal sleep patterns, which are directly linked to pineal gland dysfunction. The pineal gland is
highly susceptible to environmental toxicants. Two pervasive substances in modern industrialized nations are
aluminum and glyphosate, the active ingredient in the herbicide, Roundup. In this paper, we show how these two
toxicants work synergistically to induce neurological damage. Glyphosate disrupts gut bacteria, leading to an
overgrowth of Clostridium difficile. Its toxic product, p-cresol, is linked to autism in both human and mouse models.
p-Cresol enhances uptake of aluminum via transferrin. Anemia, a result of both aluminum disruption of heme and
impaired heme synthesis by glyphosate, leads to hypoxia, which induces increased pineal gland transferrin synthesis.
Premature birth is associated with hypoxic stress and with substantial increased risk to the subsequent development
of autism, linking hypoxia to autism. Glyphosate chelates aluminum, allowing ingested aluminum to bypass the gut
barrier. This leads to anemia-induced hypoxia, promoting neurotoxicity and damaging the pineal gland. Both
glyphosate and aluminum disrupt cytochrome P450 enzymes, which are involved in melatonin metabolism.
Furthermore, melatonin is derived from tryptophan, whose synthesis in plants and microbes is blocked by glyphosate.
We also demonstrate a plausible role for vitamin D3 dysbiosis in impaired gut function and impaired serotonin
synthesis. This paper proposes that impaired sulfate supply to the brain mediates the damage induced by the
synergistic action of aluminum and glyphosate on the pineal gland and related midbrain nuclei.
Clostridia Salmonella
Bifidobacteria
*A Samsel and S Seneff. Journal of Biological Physics and Chemistry 2017;17: 8-32
Celiac disease
*AHC Van Bruggen et al. Science of the Total Environment 2018;616-617: 255–268.
Abstract
In the present study glyphosate residues were tested in urine and different organs of dairy
cows as well as in urine of hares, rabbits and humans using ELISA and Gas Chromatography-
Mass Spectroscopy (GC-MS). The correlation coefficients between ELISA and GC-MS were
0.96, 0.87, 0.97and 0.96 for cattle, human, and rabbit urine and organs, respectively. The
recovery rate of glyphosate in spiked meat using ELISA was 91%. Glyphosate excretion in
German dairy cows was significantly lower than Danish cows. Cows kept in genetically
modified free area had significantly lower glyphosate concentrations in urine than
conventional husbandry cows. Also glyphosate was detected in different organs of
slaughtered cows as intestine, liver, muscles, spleen and kidney. Fattening rabbits showed
significantly higher glyphosate residues in urine than hares. Moreover, glyphosate was
significantly higher in urine of humans with conventional feeding. Furthermore, chronically
ill humans showed significantly higher glyphosate residues in urine than healthy
population. The presence of glyphosate residues in both humans and animals could haul the
entire population towards numerous health hazards, studying the impact of glyphosate
residues on health is warranted and the global regulations for the use of glyphosate may
have to be re-evaluated.
Entgiftung Teil I: Glyphosat
Journal of Organic Systems, 9(2), 2014
Abstract
A huge increase in the incidence and prevalence of chronic diseases has been reported in the United
States (US) over the last 20 years. Similar increases have been seen globally. The herbicide glyphosate
was introduced in 1974 and its use is accelerating with the advent of herbicide-tolerant genetically
engineered (GE) crops. Evidence is mounting that glyphosate interferes with many metabolic processes
in plants and animals and glyphosate residues have been detected in both. Glyphosate disrupts the
endocrine system and the balance of gut bacteria, it damages DNA and is a driver of mutations that
lead to cancer. In the present study, US government databases were searched for GE crop data,
glyphosate application data and disease epidemiological data. Correlation analyses were then
performed on a total of 22 diseases in these time-series data sets.
Glyphosate is the primary ingredient of Monsanto’s “Roundup”
In this comparative study, we compensated for many of the known variables that influence children's growth
and development by selecting two groups of 4-5-year-old Yaqui children who reside in the Yaqui Valley of
northwestern Mexico. These children share similar genetic backgrounds, diets, water mineral contents, cultural
patterns, and social behaviors. the major difference was their exposure to pesticides. Pesticides have been
applied to the agricultural area of the valley since the late 1940s -iIn 199, high levels of multiple pesticides were
found in the cord blood of newborns and in breast milk. Building on anthropological methods for rapid rural
appraisal of problems within the environment, a Rapid Assessment Tool for Preschool Children (RATPC) was
developed to measure growth and development. The children of the agrarian region were compared to
children living in the foothills, where pesticide use is avoided. The RATPC measured varied aspects of physical
growth and abilities t perform, or function in, normal childhood activities. No differences were found in g
patterns. Functionally, the exposed children demonstrated decreases in stamina, eye-hand coordination,
30 minute memory, and the ability' to draw a person. The RATPC pointed out areas in which more in-depth
research on the toxicology of pesticides would be valuable.
Results:
A large number of published studies support the notion that long term, low level (LTLL) exposure to
organophosphorus (OP) esters may cause autonomic, neurological and neurobehavioral effects.
The question addressed in this particular review is whether LTLL exposure to OP may produce neurotoxicity.
11 studies support the existence of a positive link between exposure to OP and neurotoxicity; appearance of
neurotoxicity does not seem to be related to the number or the intensity of acute cholinergic attacks.
Additional five studies using experimental animals, all of which showed a positive link between OP and
neurotoxicity. Seven additional case studies without controls, some involving large numbers of patients,
concluded that there is a positive link between OP and neurotoxicity. 19 additional studies investigated such a
link using cases and control groups. Of these, 15 studies (about 80%) showed a positive link and only four failed
to identify any link between OP and neurotoxicity.
There is a characteristic pattern of involvement of 15 functional indices of the autonomic nervous system
The peripheral nerve involvement in OP exposure is predominantly sensory in nature affecting both small and
large fiber populations. Neurobehavioral involvement of mainly cognitive dysfunction and other features are also
described in other studies
The parasitic nematodes Hysterothylacium sp. type MB larvae as bioindicators of lead and cadmium:
a comparative study of parasite and host tissues
H. KHALEGHZADEH-AHANGARa1, M. MALEKa1 c1 and K. McKENZIEa2
SUMMARY
Cadmium and lead concentrations were compared in tissues of cutlassfish, Trichiurus lepturus L., its intestinal
nematode Hysterothylacium sp. type MB larvae, and in water from the same location in the Sea of Oman.
Metal accumulation in hosts, parasites and sea water was measured by ICP-OES. Hysterothylacium larvae from
the intestinal lumen and visceral cavity showed much higher metal concentrations than in host tissues or sea
water. Statistical analyses revealed no significant differences in metal accumulation between infected and
uninfected hosts. Cadmium concentration in the host muscle was lower than in intestine, liver and gonad
tissues. The mean concentrations of lead and cadmium in nematodes were 289·03 and 81·5 times higher than
in host intestine, 188·4 and 225 times higher than in host muscle, 108·6 and 65·3 times higher than in host
gonads, 70·5 and 19·5 times higher than in host liver and 3351 and 148 times higher than in sea water.
The results show the value of this and possibly related nematodes as bioindicators of heavy metals and other
environmental toxins and their potential use in environmental studies.
Entgiftung Teil I: Glyphosat
Chlorella in pregnant and breastfeeding mothers
we can help create healthy babies in a toxic world
• “Effect of chlorella pyreneidosa on fecal excretion and liver accumulastion of polychlorinated
dibenzo-p-dioxin in mice” Chemosphere 2005;59 297-304
• „Maternal-fetal distribution and transfer of dioxins in pregnant women in Japan, and attempts to
reduce maternal transfer with Chlorella (Chlorella pyrenoidosa) supplements“
S.Nakano et al Chemosphere, April 2005
Abstract
High-resolution solid-state 19F NMR method has been used to examine the chemical structural
forms of fluorine introduced into the bone tissue of experimental animals (Vistar rats) exposed to
30 day fluoride inhalation. It is shown that in the bone tissue three structural forms of fluorides are
deposited: a solid phase of F-apatite and mobile nanoparticles of CaF2 and MgF2 (or KMgF3) with
the ratio of fluorine concentration in these three forms 2:2:1. During the following 30 day
rehabilitation this ratio remains constant, the total fluorine content in the bone tissue decreases 3
times and the F-apatite phase transforms into disordered (F, OH)-apatite.
A protective effect of the zeolitic enterosorbent (klinoptilolite) on fluorine binding in the
intoxication process was found, as well as the promotional effect of this enterosorbent on fluorine
excretion during the postfluoride rehabilitation.