Herpesvirus p base

(Val) Acyclovir HSV, VZV, EBV, “G”, Thymidine Kinase , Bone Marrow
o
(Val) Ganciclovir cmv , “G”, Tk, Phosphotransferase , Bone Marrow
foscarnet All, Nonnucleotide, IV Nephrotoxicity p
base
nucleoside
analogs
HIV “ 2 + 1 ” oh
NRT-1 any other class -navir p base
(pro) -tegra- chain length
NRT-i NNRT-i protease-i Entry-i Integrase-i x termination

Tenofavir(R) Efavirenz(T) Atazanavir/r(5) Maravisol Ral-tegra-vir

Emtricitabine Darunavir/r (CCRS) } base
Ritonavir gp120
Enfurvitide
(gp41) non nucleotide
analog

Interfesur Interfesur RdRp = NSSB

Relpivirine Hep B + Hep C +
Lamivudine Nevirapine Ribavirin “G” Ribavirin
Zidovudine (ART=Pregnancy) Reverse Transcriptase Direct Acting Antagonists 2 Mechanisms
Tenofavir 2 Meds Sofosuvir - NS5B - Nucleotide Analog -i
Abacavir = HSR = 5% fatal Adefoavir -uvir
Dasabuvir - NS5B - Nonnucleotide Analog -i
DidAnosine = 30% pancreatitis Lamivudine “C”
Entacavir “G” -previr - NS 3/4 A - protease -i

-asvir Ledipasvir - NSSA-i - assembly