Derivates functional ai acizieacasboxile.

ci :

" ESTER i
O
=
R -
c
' '
o -
R
OBTINERE :

IT
"

carbonic alcool

}
)
e Ae . t Eaten the

2) Amida Alcool Eater NHS

alcaoliza
'

de
t
-
t

R .

3) Cl acida- t Abood →
Ester + Hd

n ) Anhidrida '
t Abood → Eater t Acid

=
O

F? e ' e code
e
- -

Eeg
-

→
+
.

Hafey

Pnopriestati chimera : t Aida :

Estes the F- Acid t Mccool

e) R de . hidsoliza R -

Coo R
'
the E R Genet -
'
R oh
-

I
Bazica : Estes t Nam - s
fore de Nat Abood
2) R de Amon dita Ccu NHS) '
NaOH R Coo Na
'
R Coo R -
R OH
.

-
t -
t -

Estes + MHz → Amida t al cool : R -

Coor
'
t Mz - s R -
co -
Nhk t R
'
-
one

3) R de .

tzanoesterificare :

Eater Ahead totes

'
Alcool
'
t
I t : R -
Coo -
R
'
t R
"
- oh ⇐ R Coo R " tr ' oh
-
-

2) CLORVRI ACID E
--
e
R -
e
OBTINERE :
'
Cl

Acid casboxilic t Pds

Proprietary chinua :

H R . de hidrotic : R co- - d + the - s R -

code + red

2) R .
de amonoliza '
:
R -
co -
I t Nab → R -
co -
NH at Hd

3) R . de alcaolizoi : R -
co -
I + n' oh
- → R -
Coo -
R
'
t HCl
 3) A MI DE
→
Leg .
de H .

OBIINERE :

) Ac casbaxilic

}
}
i .
t NH's
2) Estes NHS t
AMONGta
'

3) Cl .
acida- t NG
" An hide.de + way Sauditot

5) Nitrile + reach pay.ae,

-

Proprietor't; chima :

) R de hidsoliza Amida Acid casboxilic NHS

'
e .
:
t Hao → t

2) R . de alcoolizd :
Amida t Alcaol → Estes + NM,

3) R . de des hidratare :
Amida Nitrile .

9) R . de redware : Amida '

t 9Mt ¥4 R -

cha -

Nhk

a) AN .
Hi D RIDE
OBTINERE :

•
Deshidsatarea inter san intramolecular .

Proprietary chinnici :

a) R . de hidsolizoi : Anhidrida '

t tho -
s 2 Acid casbaxieic

2) R . de alcoolie : Anhidrida + R oh-

- s Ester + Acid casbaxilic

3) R .
de amonoliza : Anhidridoi +
NHS - o Amida + Awol casbaxieic .

5) N i Thi Li
OBTINERE
e) Amide Nitrile .

2) R -
x t NaCN → R -
⇐N t NaCl
't -

3) Ar -
N IN ]I t CucNCI I → An CIN -

Proprietary chime'd
e) R . de hidroliza : Nihil t He → Amida
Nitric t 2 H2o → Ac .
casboxilec + NH,

2) Redware : Nitric t [n ] → Amine .

 G-rile
=

19 ) E
"

Ef
→ eats
nettle
→
h ÷ +

Naz
.

H) E

C -
e - etc
'
C
'
e -
e
-
-
ee
'
c -
c -

e
-
e

' '
o -

c o -
c -
c d o -
C -
C
l l
c c

* to
C- c- C - c
'
l O -
C
c

42 ) D
foot
Fye
"

1061 B X Acid oalicilic

- one t - code →

t
gj
a-

Re ) 215) E
COOH
149 ) D
-

Mooc C
Huffer +3km -

- >
c
y
Coen
-
-
- -

on
Mooc -
Coon t C -
C
-

dm 'd
d econ

d- c
'

Neo) D E)
'
- the → tfnaehe
a
Cang Oz :

° 231 ) A
C
-
-
the re
-
e -
c 't
C
f
'
e
GHz Cates c e
-
c
-

e
-
o - -
-
t
" ng
C C oh
-

C oh
y,
-
-

c
c- c' -
' '
- m m

Koo
c
cans
o -
c -

Egon
-
e -

-
-
O
c '
c -
C -

c e

C
 Hzc CK -

'
ng
-

9- Chez
du
301 am

re re Q
R out C C c Chez Cody HC C
Cao
-

t
-

→
- -

CHECK
-

'
o
-
n 3 '
e -

'
C -
c

MR -

em
= Cm HD
2mt2
= 12M t2nt2te6 =
the net glmol
Mester = 24+32+37 R -
( lhntlf -
et ) =

=
59 t Mn te = Goth w
g lmof
initial -- 14 ntlf

f - >
1268
final Mnt be

Mnt 60
14ns tlf
136%5,5 lhntlf
t = ⇐
e 2
25
.

1,37 . I> 37 .

9 if
)
"
+60¥
⇐ 14 n t tf t 1,37 ( th n tis - th n - -

5,98 10,96
⇐ 1,37 ( th n tht) =
42 ⇐
13,7 13,7
⇐ 19 , Hm +24,66 = 42¥ 4200 -

-1g
19
27,66
29,66
>

⇐ 15,18 n -
17,34 -

17,33 t
me
24,66

Et n
- h M EE da -
-

Gotjtmol -72 glmol

Hest - he glmol
72 et 136,862.72 =

too

371

Cuz - Cock → CnH2n 02 532

321
48,69 . 48,69 .

M
1619756
th
- 12Mt Ln the =
14Mt 16
291,85
In 14 n t 16 12mi C
48674
6,4
-
- -
- - - -

yg
In toe 48,64 - -

778,24
- -

680,96
-
- -

1200 n
= 48,64 ( 14 n the )
120am = 680,56+778,24 ⇐
n

E'
519,09nF Fff ,
24 ⇐ w - 4,5 12 n