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Neuropsychiatric aspects of traumatic brain injury file:///C:/Users/USER/AppData/Roaming/Mozilla/Firefox/Profiles/c2y...

Apathy

Apathy refers to a syndrome of disinterest, disengagement, inertia, lack of


motivation, and absence of emotional responsivity. The negative affect and cognitive
deficits seen in patients with depression are not seen in patients with apathy. Apathy
may be secondary to damage of the mesial frontal lobe (Duffy and Campbell, 1994). It
often responds well to psychostimulants, dextroamphetamine, amantadine, or
bromocriptine (Gualiteri, 1991).

Behavior Dyscontrol Disorder

This is complex syndrome characterized by disturbance in mood, behavior and


cognition (Rao and Lyketsos, 2002). The disorder has been subdivided into two
variants: (1) major variant, in which the symptoms are chronic, persistent and severe
and (2) minor variant, in which the symptoms are acute and transient.

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