Y During "Do A y During "Do A Step. N Ot An Action

DIFFERENCES FROM PANDEMIC
®
TM
CREDITS If you’ve played the original Pandemic,
Game Design: Matt Leacock Pandemic: Hot Zone differs as follows:
Producer: Michael Sanfilippo • There are only 3 diseases
Editing: Justin Kemppainen, (instead of 4).
Steven Kimball • During setup, the number of cards
In Pandemic: Hot Zone–North America, you are members of a specialized disease-
fighting team. Using your unique skills, you must work together to stop the spread of Graphic Design: Dan Gerlach, drawn is slightly different.
diseases across North America while working to discover the cures. Samuel R. Shimota
• To discover a cure, players need only
Cover Art: Atha Kanaani 4 cards (instead of 5).
CONTENTS & ASSEMBLY Character Art: Chris Quilliams • There is only 1 research station
You will need: (in Atlanta). Players can’t build
Art Direction: Bree Lindsoe
• 17 sheets of paper (A4 or US Letter) more research stations or take
Managing Art Director: Samuel R.
shuttle flights.
• Miscellaneous small objects to use as disease cubes, player pawns, and other Shimota
markers (see below). • There are only 3 Epidemic cards in
Managing Game Designer: Justin
the player deck, and all of them are
MONTRÉAL
Kemppainen
0
2 2 3 4 TORONTO
BOSTON
CALGARY 1
used every game.
MINNEAPOLIS
The board is laid out in 4 pieces. Cut out the pieces and glue
SEATTLE 2
CHICAGO
Publisher: Steven Kimball
NEW YORK
3
or tape them together to form the map of North America.
DENVER
SAN FRANCISCO INDIANAPOLIS
WASHINGTON
• Diseases cannot be eradicated.
DALLAS
PLAYER TURN
PHOENIX 1. Do 4 Actions
LOS ANGELES ATLANTA
Playtesters: Jeff & Sarah Erwin,
2. Draw 2 Player Cards
3. Draw Infection Cards
Hand size is 6 cards
at all times
MONTERREY
MIAMI
NEW ORLEANS
HAVANA SANTO DOMINGO
Bree Lindsoe, Kahla Gleason, • The Researcher and Dispatcher
Jasmine Radue
GUADALAJARA CIUDAD DE MÉXICO TEGUCIGALPA
effects are slightly altered.
4 4 4
1 Game Board
38 Player Cards Special thanks to Donna Leacock, • Crisis cards can be added to
Hillary Carey, Chris & Kim Farrell, increase the difficulty.
The 24 City cards, 3 Epidemic cards, 4 Event Rich Fulcher, Ken Tidwell, Corbin Nash,
ATLANTA
1. INCREASE
EPIDEMIC
EVENT
TIME
BORROWEDActions”
Play during “Do
step. Not an action.
CRISIS
FAILURE
LOGISTICS ely,
Play immediat
then discard.
cards, and 7 Crisis cards all have the same Jim Cote, Steve Duff, Wei-Hwa Huang,
&, for additional testing, Beth Heile &
P�486,000
Advance the Infection
Player card back. The 24 Infection cards have
Rate marker.
2. INFECT
Draw the bottom card
John Knoerzer.
from the Infection deck
and place 3 cubes on that
a separate Infection card back.
city. Discard that card.
3. INTENSIFY Resolve the “Draw Infection
Cards” step twice this turn. If
USA Shuffle the cards in the The current player can do 2 the “One Quiet Night” event
Infection discard pile additional actions this turn. is played, resolve the step
and put them on top of once instead.
the Infection deck.
24 City 3 Epidemic cards 4 Event 7 Crisis Very special thanks to Tom Lehmann
cards cards cards for his assistance.
ACTIONS
Treat Disease
Z-Man Games is committed to diverse
representation and accessible gaming
Remove 1 disease cube from your city. If
that disease is cured, remove all cubes
of that color from your city instead.
ATLANTA Share Knowledge ACTIONS
Give or take the City card matching your
city from a player in your city. Drive/Ferry MEDIC
Move to a connected city.
Discover a Cure » When you do the
for all. If you have any concerns
In Atlanta, discard 4 City cards of the
Direct Flight Treat Disease
same color to cure that disease.
Discard a City card to move directly to action, remove all
that city. the cubes of 1 color.
Charter Flight » At any time, remove
Discard the City card matching your city
all the cubes of cured
or suggestions, please contact us
to move directly to any city.
diseases in your city
for free.
24 Infection Cards 4 Reference Cards 4 Character Cards
through our website.
® 1995 County Road B2 West
Use small pieces for Use 3 pieces for cure vials, Roseville MN 55113 USA
48 Disease Cubes disease cubes, 16 each in 3 3 Cure Vials
ideally in the same 3 colors as (651) 639-1905
(16 each of 3 colors) different colors. (1 each of 3 colors) the disease cubes. info@ZManGames.com
Use 4 different-colored © 2020 Z-Man Games. Pandemic and Z-Man Games are ® of Z-Man
Use 2 different pieces for Games. Hot Zone is a TM of Z-Man Games. Gamegenic and the Gamegenic
pieces as player pawns. 1 Infection Rate marker the Infection Rate and logo are TM/® and © Gamegenic GmbH, Germany. Actual components may
4 Player Pawns Outbreak markers. vary from those shown.
(1 each of 4 colors)
1 1 Outbreak marker 2
2 2 3 4 TORONTO
BOSTON
CALGARY 1
MINNEAPOLIS
SEATTLE 2
SETUP 5. Shuffle the Hand Size
MONTRÉAL
KEY CONCEPTS
CHICAGO 0
MONTRÉAL
2 2 3 4
Infection deck and 2 2 3 4
NEW YORK
3 0
TORONTO
A hand size of 6 cards applies at all times.
TORONTO
1. Place the board within easy reach of placeMONTRÉAL
it facedown
BOSTON
CALGARY 1
all players. Sort the disease cubes and
SAN FRANCISCO
on the board.
DENVER
0 CALGARY
INDIANAPOLIS COOPERATION BOSTON
MINNEAPOLIS 1 Whether it is your turn or not, if you ever
3 4 TORONTO DALLAS
WASHINGTON
MINNEAPOLIS
SEATTLE have2 more than 6 cards in your hand, you
cure vials by color and place them near Pandemic: Hot Zone–North CHICAGOAmerica is a
DENVER
Flip over 2 Infection SEATTLE
BOSTON PLAYER TURN
2
must discard City cards or play Event cards
the board.
CALGARY 1 1. Do 4 Actions cooperative game; all the players are on the
CHICAGO NEW YORK
LOS ANGELES cards. Place 3 cubes of
PHOENIX
ATLANTA
2. Draw 2 Player Cards NEW YORK
until
3
you have only 6 cards left.
MINNEAPOLIS same
team and win or lose 3
together. Each
2. Place the Outbreak and the matching color on
DENVER
SAN FRANCISCO
Hand size is 6 cards MONTRÉAL
member of your team has a 0character WASHINGTON with
at all times INDIANAPOLIS
PLAYER TURNS
DENVER
MONTERREY
Infection Rate markers at 2 2 each 3 of those 4 cities.
SAN FRANCISCO 2 INDIANAPOLIS DALLAS
MIAMI TORONTO
special abilities to help your team succeed,
WASHINGTON
the start of their respective CHICAGO NEW ORLEANS DALLAS
Next, flip over 2 more
PLAYER TURN
PHOENIX and each player BOSTON keeps their hand faceup 1. Do 4 ActionsPlayers take turns in clockwise order,
TEGUCIGALPA
tracks, as shown.
MONTRÉAL CALGARY
NEW YORK LOS ANGELES PLAYER TURNATLANTA 1
cards and place 2
DOMINGO in front of them so4 Actions
that all players can seeHand following these steps each turn. The first
0 LOS ANGELES
3
PHOENIX
HAVANA SANTOATLANTA
1. Do 3. Draw Infection Cards
MINNEAPOLIS 2. Draw 2 Player Cards size is 6 cards
3. TORONTO
Give each player cubes of the matching each other’s cards.
MONTERREY
at all times
time you play, don’t feel like you have to
DENVER at all times
1 reference card. Give BOSTON INDIANAPOLIS SEATTLE color on eachCIUDAD
MEDIC
of DEthose
MÉXICO
MONTERREY
TEGUCIGALPA
2 MIAMI
read the rules cover-to-cover and remember
4 Players canMIAMIdiscuss and freely give each
GUADALAJARA
1 NEW ORLEANS
» When you do the
Treat Disease
4 4
action, remove all
1 random Character cities. CHICAGO
everything. Instead, you can read the rules for
the cubes of 1 color.
WASHINGTON
» At any time, remove
NEW ORLEANS
other advice. Everyone should offer opinions
for free.
DALLAS
card to each player NEW YORK
3 HAVANA for each step, then play that step, checking the
Finally, flip over 2 more
TORONTO
and ideas, but each player decides SANTO DOMINGO
with a matching color 2 HAVANA rules as necessary if you have any questions.
cards and placePLAYER 1 cube
SANTO DOMINGO
TURN
themselves what to do during their turn.
pawn. Each player
CHICAGO
PHOENIX
DENVER
1. Do 4 Actions
MONTRÉAL
SAN FRANCISCO ATLANTA
2 2 of the
3 4 matching color
2. Draw 2 Player Cards TORONTO INDIANAPOLIS
GUADALAJARA0 CIUDAD DE MÉXICO TEGUCIGALPA
4 4 41. Do 4 Actions
places their pawn on NEW YORK GUADALAJARA
3. Draw Infection
CIUDAD DE MÉXICO
DISEASES
TEGUCIGALPA
cities. Cards
MONTRÉAL
3 on each of those WASHINGTON 4 4 4 0
Atlanta. Return any 2. Draw 2 Player Cards
BOSTON
CALGARY DALLAS
Hand size is 6 cards 2 2 3 14
TORONTO
atMINNEAPOLIS
all times
unused reference cards, Character
MONTERREY Place these There are 3 different diseases threatening BOSTON
1
CALGARY
2 PLAYER TURN
North America, each identified by its
SEATTLE
DIANAPOLIS
cards, and pawns to the box. 6 Infection
PHOENIX MIAMI CHICAGO
MINNEAPOLIS
TORONTO
DENVER
1. Do 4 Actions
TORONTO
TEGUCIGALPA
TORONTO
DENVER
WASHINGTON NEW ORLEANS
LOS ANGELES
cards faceup
ATLANTA own color and represented on the board
1.2 DO 4 ACTIONS
SEATTLE
NEW YORK
3
4. There are 24 Player 3. Draw Infection Cards
EVENT
CHICAGO
by cubes.
BORROWED
in the Infection
TIME
MIAMI
Play during
step. Not an“Do Actions”
00 action.
P�463,0
cards with city names
DENVER NEW YORK
3
PLAYER TURN
SAN FRANCISCO
discard pile. MONTERREY INDIANAPOLIS
at all times You can do up to 4 actions each turn. You
ATLANTA
on them, and 4 cards 1. Do 4 Actions HAVANA DALLAS
SANTO
USA
DOMINGO
The curr
addition ent player
al actions can do 2
this turn
WASHINGTON
DENVER
can do the same action multiple times on
SAN FRANCISCO
.
INDIANAPOLIS
labeled “Event.” Shuffle3. Draw Infection Cards 6. The player with the PLAYER TURN
MIAMI WASHINGTON
the same turn. Actions are summarized on
MIAMI NEW ORLEANS DALLAS
these 28 cards together LOS and
Hand size deal 2
is 6 cards highest
PHOENIX
city population ATLANTA 1. Do 4 Actions
Each city on the board has a matching PLAYER TURN the double-sided reference cards. Some
ANGELES 2. Draw 2 Player Cards
at all times P�463,000 3. Draw Infection Cards MONTRÉAL
GUADALAJARAfaceup to CIUDAD
each player (3 each if you TEGUCIGALPAon
DE MÉXICO 2
a2card3 in their 4
hand LOS ANGELES
Hand size is
at all times
0
6 cards
PHOENIX
Infection card. WhenATLANTA an Infection card is 2.1. Draw
TORONTO
Do 4 Actions
characters
2 Player Cards have actions only they can do.
have only 2 players). takes the first turn.
MONTERREY
4 4 4 3. Draw Infection Cards
MIAMI
drawn, place a SANTO
1 HAVANA cubeDOMINGO in the matching city atHand toall times BOSTON
Drive/Ferry
MIAMI
CALGARY size is 6 cards
W ORLEANS NEW ORLEANS MINNEAPOLIS
represent the spread of disease there.
MONTERREY
Then, divide the rest of these cards The Crisis cards add optional
2
SEATTLE
CRISIS
FAILURE
LOGISTICS ely,
Move your pawn to a city
then discard.
MIAMI
Play immediat
into 3 facedown piles (as evenly as challenge, but they are not used
NEW ORLEANS CHICAGO
3 Disease cubes must be treated promptly; if connected by a line to
SANTO DOMINGO HAVANA NEW YORK
TEGUCIGALPA
GUADALAJARA CIUDAD DE MÉXICO
possible). Shuffle 1 Epidemic
HAVANA card
SANTO DOMINGO during your first game; return
the diseases spread 4 out4of control, 4
Resolve the “Draw Infection
you will
the “One Quiet Night” event
your city.
is played, resolve the step
DENVER once instead.
themGUADALAJARA
to the box.CIUDAD
When you have TEGUCIGALPA
HAVANA
facedown into each pile. Stack these
SANTO DOMINGO
lose the game.
DE MÉXICO WASHINGTON
piles to form the Player deck (smaller experience with the game, if you
4 USA wish to 4 4
Direct Flight
DALLAS
CIUDAD DE MÉXICO TEGUCIGALPA
PLAYER CARDS
PLAYER TURN
play with Crisis cards, see “Crisis Cards” on
GUADALAJARA
piles on the bottom, if any) and place
TEGUCIGALPA the 4 4 4
Discard a City card from
LOS ANGELES ATLANTA
deck on the board. 4 4 4 page 7 for rules and setup.
your hand to move to the
MONTERREY
at all times
Each player has a hand of EVENT
BORROWE
D TIME
city shown on that card.
Play during
MIAMI step. Not an“Do Actions”
Player cards, including City
action.
MIAMI
000
P�463,
NEW ORLEANS
cards and Event cards. During USA
The curr
addition ent player
al acti can
ons this do 2
Charter Flight
the game, you discard City cards
turn.
to accomplish certain goals and play Event Discard the City card from
your hand that shows the
4 4 4
cards for their unique effects; make sure to
EPIDEMIC
1. INCREASE
EPIDEMIC
1. INCREASE
EPIDEMIC
1. INCREASE
place any played or discarded Player cards city you are in to move to
any city.
Advance the Infection Advance the Infection Advance the Infection
Rate marker. Rate marker. Rate marker.
in the Player discard pile.
2. INFECT 2. INFECT 2. INFECT
Draw the bottom card Draw the bottom card Draw the bottom card
from the Infection deck from the Infection deck from the Infection deck
and place 3 cubes on that and place 3 cubes on that and place 3 cubes on that
city. Discard that card. city. Discard that card. city. Discard that card.
3. INTENSIFY 3. INTENSIFY 3. INTENSIFY
Shuffle the cards in the Shuffle the cards in the Shuffle the cards in the
Infection discard pile Infection discard pile Infection discard pile
and put them on top of and put them on top of and put them on top of
the Infection deck. the Infection deck. the Infection deck.
3 4
MONTRÉAL
0
2 2 3 4 TORONTO
BOSTON
CALGARY 1
MINNEAPOLIS
SEATTLE
DALLAS
P�1,341,000
CHICAGO
2
MONTRÉAL
2. DRAW 2 PLAYER CARDS 3. DRAW INFECTION
CARDS
NEW YORK
0
After doing actions, draw the top 2 cards
3 2 2 3 4 TORONTO
USA
DENVER BOSTON
CALGARY 1
together from the Player deck. If there are
One at a time, flip over a
MINNEAPOLIS
WASHINGTON
DALLAS
2
not enough cards left in the deck to draw 2
SEATTLE
number of Infection cards
PLAYER TURN CHICAGO
CALGARY
2 2 3
cards, do not shuffle the Player discard pile
P�1,239,000
LOS ANGELES ATLANTA NEW YORK
SEATTLE
2. Draw 2 Player Cards 3
equal to the current infection
P�724,745
Hand size is 6 cards DENVER
at all times
MONTERREY
INDIANAPOLIS
P�872,000 MIAMI
SAN FRANCISCO
Canada
DALLAS
INDIANAPOLIS
WASHINGTON to form a new deck. The game immediately rate (indicated by the Infection
ends and all players lose (see “Losing and
NEW ORLEANS USA
PLAYER TURN
Rate track). For each flipped card, infect the
Winning” on page 6).
LOS ANGELES ATLANTA
matching city and discard the card to the
HAVANA 2. Draw 2 Player Cards
USA SANTO DOMINGO 3. Draw Infection Cards
at all times
SEATTLE
Epidemic Cards Infection discard pile.
MONTERREY
FLIGHT EXAMPLE SHARE KNOWLEDGE EXAMPLE
MIAMI
4 4 4 NEW ORLEANS
Bridget is in Calgary with the Calgary If your draw includes any Epidemic cards, To infect a city, place
Bridget is in Havana and wants to HAVANA SANTO DOMINGO
TORONTO
City card in hand, and Char is in Seattle immediately do the following: 1 matching cube on
get to San Francisco to Treat Disease.
that city. If the city
She has the Indianapolis and Dallas with the Seattle City card in hand.
4 4 4
1. Increase: Move MONTRÉAL
On his turn, Alan Drives twice from 2 already 4 has 3 cubes SAN of FRANCISCO
City cards in hand. During her turn, the Infection 2 3 TORONTO
she does the Direct Flight action and Chicago to Calgary, does the Share Rate marker 2 2 3that color, 4CALGARYdo not place a TORONTO BOSTO
Knowledge action to take the Calgary fourth cube. Instead, an
discards the Indianapolis card to
MINNEAPOLIS
1 space to the
SEATTLEoutbreak CALGARYoccurs in the
move directly to Indianapolis, Drives City card from Bridget, then Drives to right on its track.
city (see “Outbreaks” below).
CHICAGO
MINNEAPOLIS PHOEN
to Dallas, then does the Charter Flight Seattle. On their turn, Char can do the LOS ANGELES
MONTRÉAL
NEW YORK
2. Infect: 2Draw 3 the
0
Share Knowledge action to give the
MINNEAPOLIS
action and discards the Dallas card 2 4
SEATTLE IfTORONTO
you need DENVER to place a cube, but there are
bottom card from
to move directly to San Francisco. Seattle City card to Alan. During each CALGARY SAN FRANCISCO
no cubes of that color BOSTON
left1 INDIANAPOLIS
in the supply, the CHICAGO
the Infection deck WASHINGTON
Share Knowledge action, both players
MINNEAPOLIS
game immediately ends and all players lose
DALLAS
Treat Disease and place
SEATTLE 3 matching 2
agree to give or take the card. (see
CHICAGO “Losing and Winning” on page 6).
PLAYER
Remove 1 disease cube cubes on that city.LOS ANGELES PHOENIX
ATLANTA 1. Do 4 A
2. Draw
Discover a Cure DENVER
NEW YORK 3. Draw
3
from your city, returning it to If that city SAN
would have 4 or more
FRANCISCO
It is rare but possible for the Infection deck Hand siz
INDIANAPOLIS at all tim
the supply. You must be in Atlanta to do this SAN FRANCISCO cubes of the same color, fill it to 3
DENVER
to
INDIANAPOLIS
run out of cards.
MONTERREY
If it does, shuffle the
MIAMI
action. Discard 4 City cards of cubes instead, then DALLAS an outbreak Infection discard DALLAS
pile to form
WASHINGTON
a new deck.
NEW ORLEANS
If this disease color has been
the same color from your hand to occurs (see “Outbreaks” to the right).
cured (see “Discover a Cure” Outbreaks PLAYER TURN
discover the cure for that disease. LOS ANGELES Discard the PHOENIX
Infection card to the ATLANTA
PHOENIX
1. Do 4 Actions
HAVANA SANTO D
to the right), remove all cubes of that color LOS ANGELES If you would place Handa fourth
3. Draw Infection Cards ATLANTA GUADAL
Place the matching cure vial onto its cure Infection discard pile. MONTRÉAL
size is 6 cards
from your city instead.
at all times
MONTERREY
cube of
GUADALAJARAthe same color
CIUDAD DE MÉXICO on
0
TEGUCIGALPA
space on the board.
33. Intensify: Shuffle all cards in the NEW ORLEANSTORONTO 4
2 2 4 a city, an outbreak
MIAMI
of that
Share Knowledge Infection discard pile, including
MONTERREY
Curing diseases is how you win the game; color occurs instead. Do not
BOSTON
If there is another player in you must cure all 3 diseases to win. Curing the card drawn from the bottom
CALGARY
placeHAVANAa fourth cube in the
1
SANTO DOMINGO NEW ORLEANS
your city and both players diseases makes the Treat Disease action during the “Infect”MINNEAPOLIS
step, and outbreaking city. When an
agree, you can do one of more effective against that disease, but place themGUADALAJARA
facedown CIUDAD on top of the outbreak occurs, move
SEATTLE DE MÉXICO TEGUCIGALPA
2
the following: Infection deck. 4 4 4
TORONTO
keep in mind: the Outbreak
CHICAGO marker
• Give the City card matching your city to • Curing a disease does not immediately After resolving Epidemic cards, return them down 1 space on NEW YORK
3
MONTRÉAL
that player. remove cubes already on the board. to the box. If you draw 2 Epidemic cards
2 2 3 the 4Outbreak track. TORONTO
• Take the City card matching your city at once, do the 3DENVER
steps above, then repeat Then,
GUADALAJARAplace 1 cube
CIUDAD DE MÉXICO TEGUCIGAL
BOSTON
• Curing a disease does not prevent
CALGARY
new
from that player.
SAN FRANCISCO
them. Epidemic cards are not drawn into INDIANAPOLISof the outbreaking
MINNEAPOLIS
cubes from being placed on the board. WASHINGTON
your hand and do not count toward your
DALLAS
SEATTLE
disease on each city
Reminder: Any time you get a card, check
CHICAGO
hand size. Do not draw another card to connected to the NEW YORK
to be sure you have not exceeded the outbreaking city. PLAYER TURN
replace an Epidemic card.
hand size of 6 cards. LOS ANGELES
PHOENIX
SAN FRANCISCO ATLANTA
DENVER
1. Do 4 Actions
INDIANAPOLIS
WASHINGTON
DALLAS 3. Draw Infection Cards
5 at all times 6
PLAYER TURN
MONTERREY PHOENIX
ATLANTA 1. Do 4 Actions
LOS ANGELES 2. Draw 2 Player
3. Draw Infection
Chain Reaction Outbreaks TURN END
While resolving an outbreak, if you add
CRISIS CARDS FINE POINTS
After drawing and resolving Infection cards, After you have played the game a few • If you draw an Epidemic or Crisis card
a cube to a city that already has 3 cubes
your turn ends, and the player to your left times using the basic rules, you can on your turn, you do not draw a card to
of that color, do not place a fourth cube.
takes the next turn. test your skills against dangerous and replace it.
Instead, after you resolve the outbreak in
the current city, a chain reaction outbreak unpredictable Crisis cards. • The hand size of 6 Player cards applies
occurs in each of those cities. EVENT CARDS at all times. If you receive a card from
SETUP another player or draw cards during your
When a chain reaction outbreak occurs, Players can play Event cards at any EVENT
turn that give you more than 6 cards,
TIME
BORROWEDActions”
Play during “Do
Shuffle all 7 Crisis cards facedown. During
step. Not an action.
move the Outbreak marker down 1 space. time, even during other players’
you must play Event cards or discard City
Then, place cubes in the connected cities. turns. Playing an Event card is not step 5 of setup, in addition to shuffling
The current player can do 2
additional actions this turn.
cards until you have only 6 cards in hand.
Do not add a cube or advance the outbreak an action, and the player who plays Epidemic cards into 3 separate piles,
the card chooses how it is used. shuffle a number of Crisis cards facedown • You must be in Atlanta to do the
marker for any cities that already had an
into each pile to adjust difficulty as follows: Discover a Cure action.
outbreak or chain reaction outbreak while Event cards cannot be played while you
MONTRÉAL
resolving the current Infection card. • Standard difficulty: 1 Crisis card per pile. • You win immediately when you
are already resolving a card. This means
0
3 4
discover the third cure. You do not need
that once an Infection card is drawn,
TORONTO • Heroic difficulty: 2 Crisis cards per pile. to remove the remaining cubes from
TORONTO
it’s too late to play an Event card to the board.
BOSTON
MONTRÉAL
1 Return the unused Crisis card(s) to the box
0stop that cube from being placed (or an
CALGARY 0
MONTRÉAL
3 4 TORONTO
outbreak occurring).
MINNEAPOLIS
TORONTO without looking at them. • When an effect refers to “your city,” it
CALGARY
BOSTON
1 BOSTON
1 means the city your pawn is currently in.
2
LOSING & WINNING
EAPOLIS MINNEAPOLIS
2
• Whenever an effect allows you to
CHICAGO
2
CHICAGO CHICAGO interact with another player during your
NEW YORK The game immediately ends and all players
NEW YORK turn (moving their pawn, giving/taking
3
3
NEW YORK
3
lose if any of the following occur: cards), both players must agree.
DENVER
INDIANAPOLIS
• The Outbreak marker
INDIANAPOLIS
DENVER WASHINGTON WASHINGTON • Due to outbreaks, a city can have up to 3
CHAIN OUTBREAK EXAMPLE reaches the last space of
DALLAS
INDIANAPOLIS
cubes of each color on it.
the Outbreak WASHINGTON
track.
PLAYER TURN
CRISIS CRISIS CRISIS
PLAYER TURN LOGISTICS FAILURE
CRISIS
ely, then discard.
PLANES GROUN
CRISIS
DED
ely. Stays in play.
UNACCEPTAB CRISIS
LE LOSSES
ely, then discard.
Toronto
DALLASand Montréal2. Draw 2 Playerboth have 32.1. Draw
Play immediat Play immediat Play immediat
S
HOT SPOT ely, then discard. LIMITED OPTION CONTAMINATION
1. Do 4 Actions
PHOENIX
• If the “Hot Spot” Crisis card would place
ely. Stays in play. ely, then discard.
ATLANTA ATLANTA Do 4 Actions Play immediat Play immediat Play immediat
Cards 2 Player Cards
Hand size is 6 cards • You need to place a cube on the board,
blue cubes on them. Hand sizeDuring
is 6 cards
at all times
the “Draw at all times
Players cannot do the
Direct Flight or Charter Draw the bottom card from cubes on a city that already has 1 or
but there are no cubes ofTURN
that color left
Flight actions. the Infection deck. Return
PLAYER
the “One Quiet
DrawNight” eventcard from
the bottom Reduce players’ handsize
Choose 1 pawn
and 3and check
Infection Cards” step, the Toronto more cubes of that color, instead fill that
that Infection card
is played,the
resolve the step
Infection deck and place When the to 5 cards.
next Crisis Discard
card is or play matchingthe color
cubes to of
thetheir
box.city. Place
MONTERREY once3 instead.
matching cubes on that Eventthis
drawn, discard cards as needed.
card. 1 cube of that color on each
city. Discard that card. When the next Crisis card is connected city.
drawn, discard this card.
PHOENIX in the supply.
MIAMI
1. Do 4 Actions
city to 3 cubes, then an outbreak occurs.
MIAMI
NEW ORLEANS
Infection card is drawn. Instead of
NEW ORLEANS ATLANTA
placing a fourth cube on Toronto, a 3. Draw Infection Cards
• You do the “Draw 2 Player Cards” step,
blue HAVANA
outbreak occurs. Blue
SANTO DOMINGOHAVANA
cubes are
SANTO DOMINGO
but there are not
enough cards left in
at all times PLAY CHARACTER
MONTERREY
placed on New York and Chicago, and the deck before drawing (either 1 or 0
When you draw a Crisis card, resolve
CLARIFICATIONS
ICO
GUADALAJARA
instead
TEGUCIGALPA
CIUDAD DE MÉXICO
of placing4 TEGUCIGALPA
a fourth 4 cube on 4 cards are left).
MIAMI
4
NEW ORLEANS
4 4 its effect. Some Crisis cards have an • The Dispatcher’s second effect
Montréal, a chain reaction outbreak moves another player’s pawn to a city
When the cures for all 3 diseases have immediate effect, while other Crisis cards
occurs in Montréal. Blue cubes are connected to that player’s city, not to a
been discovered, the players immediately remain in play until the next Crisis card
placed on Boston and New York, but city connected to the Dispatcher’s city.
win HAVANA
the game! is drawn. Just like Epidemic cards, do not
not on Toronto, because Toronto SANTO DOMINGO
draw another card to replace a Crisis card. • The Medic’s automatic removal of cubes
has already had an outbreak while You do not need to remove all cubes from
can occur on other players’ turns (such
resolving this Infection card. the board to win. After your team discovers If you draw both an Epidemic card and a
as if he is moved by the Dispatcher or
CIUDAD DE MÉXICO the cures for the diseases, local doctors are
TEGUCIGALPA Crisis card when drawing Player cards,
GUADALAJARA the “Airlift” event).
able to treat anyone still 4affected
4 by them
4 resolve the Crisis card first. If you draw 2
with the cures your team discovered. Crisis cards at once, you choose the order • The Researcher’s effect is limited to
to resolve them. giving any City card, not taking.
7 8
INDIANAPOLIS CHICAGO TORONTO MONTRÉAL
P�872,000 P�2,716,000 P�2,732,000 P�1,705,000
USA USA Canada Canada
Print & Play Edition Print & Play Edition Print & Play Edition Print & Play Edition
BOSTON NEW YORK WASHINGTON ATLANTA

P�685,000 P�8,623,000 P�694,000 P�486,000
USA USA USA USA
GUADALAJARA NEW ORLEANS MIAMI HAVANA
P�1,495,000 P�393,000 P�463,000 P�2,130,000
México USA USA Cuba
SANTO DOMINGO TEGUCIGALPA CIUDAD DE MÉXICO MONTERREY

P�965,000 P�1,363,000 P�8,851,000 P�1,136,000
República
Dominicana Honduras México México
DALLAS SEATTLE MINNEAPOLIS DENVER
P�1,341,000 P�724,745 P�422,000 P�705,000
USA USA USA USA
CALGARY PHOENIX SAN FRANCISCO LOS ANGELES

P�1,239,000 P�1,626,000 P�884,000 P�3,990,000
Canada USA USA USA
CRISIS CRISIS CRISIS CRISIS
HOT SPOT ely, then discard. FAILURE rd.
LOGISTICS ely
NDED
PLANES GROUStays in play. LIMITED OPT IONS
y.
, then disca ely. ely. Stays in pla
Play immediat Play immediat Play immediat Play immediat
Draw the bottom card from Players cannot do the Reduce players’ hand size
the Infection deck and place Direct Flight or Charter to 5 cards. Discard or play
3 matching cubes on that Flight actions. Event cards as needed.
the “One Quiet Night” event
city. Discard that card. is played, resolve the step When the next Crisis card is When the next Crisis card is
once instead. drawn, discard this card. drawn, discard this card.
CRISIS CRISIS CRISIS EVENT

ILURE ATION rd. ABLE LOSSrdES BORROWED TIME
SANITATION ,FA
then discard.
ely
CONTAMINely, then disca
UNACCEPTely, then disca . o Actions”
Play during “D tion.
Play immediat Play immediat Play immediat step. Not an ac
Choose 1 pawn and check Draw the bottom card from

Advance the Infection Rate the color of their city. Place the Infection deck. Return The current player can do 2
marker (unless it is already 1 cube of that color on each that Infection card and 3 additional actions this turn.
at the end of the track). connected city. matching cubes to the box.
EVENT EVENT EVENT
AIRLIFT e. Not an actio
n. REMOTE TREA
TMENT
e. Not an actio
n. ONE QUIETe.N
IGHT
Not an action.
EPIDEMIC
Play at any tim Play at any tim Play at any tim
1. INCREASE
Advance the Infection
Rate marker.
2. INFECT
Draw the bottom card
from the Infection deck
and place 3 cubes on that
city. Discard that card.
3. INTENSIFY
Return any 2 cubes Skip the “Draw Infection Shuffle the cards in the
Move 1 pawn to any city. Cards” step this turn. Infection discard pile
from the board to the supply.
and put them on top of
the Infection deck.
ACTIONS
ACTIONS
Charter Flight
Direct Flight
Drive/Ferry
Charter Flight
Direct Flight
Drive/Ferry
that city.
Discard a City card to move directly to

that city.

Print & Play Edition
EPIDEMIC EPIDEMIC
ACTIONS
ACTIONS
1. INCREASE 1. INCREASE
Discover a Cure
Share Knowledge
Treat Disease
Discover a Cure
Share Knowledge
Treat Disease
city from a player in your city.



city from a player in your city.


Advance the Infection Advance the Infection

Rate marker. Rate marker.
2. INFECT 2. INFECT
Draw the bottom card Draw the bottom card
from the Infection deck from the Infection deck
and place 3 cubes on that and place 3 cubes on that
city. Discard that card. city. Discard that card.
3. INTENSIFY 3. INTENSIFY
Shuffle the cards in the Shuffle the cards in the
Infection discard pile Infection discard pile
and put them on top of and put them on top of
the Infection deck. the Infection deck.
Print & Play Edition Print & Play Edition
GENERALIST
» You can do up
to 5 actions on
your turn.
MEDIC
» When you do the
Treat Disease
action, remove all

the cubes of 1 color.
» At any time, remove
for free.
ACTIONS Print & Play Edition ACTIONS Print & Play Edition
Drive/Ferry Treat Disease DISPATCHER
Move to a connected city. Remove 1 disease cube from your city. If » Action: Move any
of that color from your city instead. pawn directly to any
Direct Flight other pawn’s city.

Share Knowledge
that city. Give or take the City card matching your » Action: Move
city from a player in your city. another player’s
Charter Flight Discover a Cure pawn to a
Discard the City card matching your city connnected city.
to move directly to any city. same color to cure that disease.
ACTIONS Print & Play Edition ACTIONS Print & Play Edition
Drive/Ferry Treat Disease RESEARCHER
Move to a connected city. Remove 1 disease cube from your city. If
that disease is cured, remove all cubes » Action: Give a
of that color from your city instead. City card from your
Direct Flight hand to another

Share Knowledge
Discard a City card to move directly to player in your city.
that city. Give or take the City card matching your
city from a player in your city. The card does not
need to match
Charter Flight Discover a Cure your city.
Discard the City card matching your city In Atlanta, discard 4 City cards of the
to move directly to any city. same color to cure that disease.
MONTRÉAL ATLANTA
TORONTO WASHINGTON
CHICAGO NEW YORK
INDIANAPOLIS BOSTON
HAVANA MONTERREY
MIAMI CIUDAD DE MÉXICO
NEW ORLEANS TEGUCIGALPA
GUADALAJARA SANTO DOMINGO
DENVER LOS ANGELES
MINNEAPOLIS SAN FRANCISCO
SEATTLE PHOENIX
DALLAS CALGARY
2 2 3 4
CALGARY
MINNEAPOLIS
SEATTLE
DENVER
SAN FRANCISCO
DALLAS
PHOENIX
LOS ANGELES
MONTERREY
MONTRÉAL
0
TORONTO
BOSTON
ARY 1
MINNEAPOLIS
2
CHICAGO
NEW YORK
3
DENVER
INDIANAPOLIS
WASHINGTON
DALLAS
PLAYER TURN
at all times
MONTERREY
SAN FRANCISCO
DALLAS
PHOENIX
LOS ANGELES
MONTERREY
GUADALAJARA CIUDAD DE MÉXICO
INDIANAPOLIS
WASHINGTON
DALLAS
PLAYER TURN
at all times
MONTERREY
MIAMI
NEW ORLEANS
CIUDAD DE MÉXICO TEGUCIGALPA
4 4 4

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DIFFERENCES FROM PANDEMIC

USA USA Canada Canada

BOSTON NEW YORK WASHINGTON ATLANTA

USA USA USA USA

México USA USA Cuba

SANTO DOMINGO TEGUCIGALPA CIUDAD DE MÉXICO MONTERREY

USA USA USA USA

CALGARY PHOENIX SAN FRANCISCO LOS ANGELES

Canada USA USA USA

CRISIS CRISIS CRISIS EVENT

Choose 1 pawn and check Draw the bottom card from

Move to a connected city.

to move directly to any city.

Move to a connected city.

Print & Play Edition

city from a player in your city.

of that color from your city instead.

same color to cure that disease.

city from a player in your city.

of that color from your city instead.

Advance the Infection Advance the Infection

Print & Play Edition

Print & Play Edition

Print & Play Edition

Print & Play Edition

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