Professional Documents
Culture Documents
Thesis RRLHemagglutination 2020
Thesis RRLHemagglutination 2020
Hemagglutination Inhibition assay can be used for diagnosing viral infection and quantifying the
specific virus antibodies that inhibit hemagglutination. An example of a virus that uses HAI is the
Influenza virus, a specific antibody binds to the surface of the virus, it inhibits the virus from binding on
the surface of the red cell and it won't form a lattice. Analysis of the HIA antibody level used for
determining the probability of having Influenza (Benoit et al.,2017), identify past exposure to the
virus(Truelove et al., 2016) and assess immune response into the virus-induced antibody (Wilson et al.,
2017). HIA used as a standard to evaluate the efficacy of the vaccine (Ng et al., 2017). Assessing
Plumbago indica and Allium sativum extract effectivity against Influenza virus using HAI (Chavan et al.,
2017)
In our research we're going to use hemagglutination assay for determining which antigen on the
red cell will Vigna radiata extract will react and determine what concentration of V.radiata and the red
cell suspension is suitable for the analysis.