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VOLUME 2/ISSUE 8 - JULY 2015

Clinically proven Obagi - Skin care for everyone


The UK’s Best Cosmeceutical,
recognised for the fourth year in
a row by the aesthetic medical
profession.
N 1 O In the
world

www.obagi.uk.com
Treating the Hyperpigmentation
Practitioners discuss
Mesotherapy
Juan Lopez shares
Online Reviews
Emily Ross

Forehead CPD the issue of


hyperpigmentation and
his treatment
protocol for
highlights the best
ways to utilise
Mr Dalvi Humzah and Anna Baker offer detail their treatment optimising skin online reviews for
their insight into forehead rejuvenation approaches hydration clinic marketing
*Mix & match across Restylane (Vital) SkinBoosters and Emervel only. Or, mix & match within Restylane dermal fillers. Cheapest item free. Free Recover Cream limited to 1 per order, per day and subject to availabili-
ty. All prices and offers are subject to VAT (unless ordered on a named patient basis), change without notice and whilst stocks last. Terms and conditions apply, and are available on request. †Skin Therapy offer is for
Aesthetic Journal readers only (quote offer code: AJ-JULY when ordering), is subject to change without notice and whilst promotional stocks last. Terms and conditions apply, and are available on request. ‡DigitRx 5%
offer excludes toxins and carriage charges, and is calculated before any VAT is due. 5% offer ending midnight on Friday 10th July 2015. Full terms and conditions are available on request.
Contents • July 2015
06 News
The latest product and industry news

14 News Special: Consumer Health Reporting


We explore the representation of aesthetics in mainstream media Special Feature
19 On the Scene Hyperpigmentation
Out and about in the industry this month Page 21

CLINICAL PRACTICE
21 Special Feature: Hyperpigmentation
We ask practitioners to share their best tips for treating hyperpigmentation

27 CPD Clinical Article Patient Relations


Mr Dalvi Humzah and Anna Baker detail the anatomy of the forehead area Handling Online Reviews
for aesthetic rejuvenation Page 57
33 Eye Rejuvenation
Dr Maryam Zamani provides an overview of aesthetic treatments for Clinical Contributors
rejuvenating the eyes, and details her ‘Tri Eye’ technique Mr Dalvi Humzah is a consultant plastic recon-
structive and aesthetic surgeon, with a BSc in
36 Aesthetics Awards 2015 anatomy. He is the lead tutor for the award-win-
We look at why you should be attending the Aesthetics Awards 2015 ning anatomy teaching programme, Facial Anat-
omy Teaching.

38 Hyaluronidase Protocol Anna Baker is a dermatology and cosmetic nurse


practitioner. She runs the nurse-led Medicos
Lee Rowe details the importance of hyaluronidase and how to use it
Rx Skin Clinic at The Nuffield Health Hospital
in Cheltenham, and is the coordinator for Facial
41 Treating Acne Scars with Fillers Anatomy Teaching.
Dr Renée Hoenderkamp shares her technique for treating acne scars with
Dr Maryam Zamani is an ophthalmologist,
dermal fillers oculoplastic surgeon and aesthetic doctor. She
qualified at the George Washington University
44 Case Study: Liposuction School of Medicine, later completing her training
Dr Amanda Wong Powell discusses the evolution of liposuction and her at the imperial College London.

own experience of performing VASER Liposuction in clinic Dr Renée Hoenderkamp is a GP registrar in


London. With a special interest in aesthetics and
women’s health, she founded The Non Surgical
49 Mesotherapy for Facial Skin Hydration
Clinic in 2011, focusing on natural looking
Juan Lopez explores the use of mesotherapy to rejuvenate and moisturise solutions for facial ageing and deformity.
the face Dr Amanda Wong Powell is a VASER
liposuction surgeon, founder of Dr. W on Harley
53 Spotlight On: Kybella Street and a member of the Royal College of
We investigate the newly FDA-approved fat reducing injection for the chin Surgeons (Edinburgh). She is also medical
director of medical training platform Meducatus.
55 Abstracts Lee Rowe is an independent nurse prescriber
A round-up and summary of useful clinical papers and aesthetic nurse. Leaving the NHS some years
ago, she set up Innersense Aesthetics with fellow
nurse Lorraine O’brien and now works full time at
IN PRACTICE her York-based clinic.
Juan Lopez is an aesthetic nurse and
57 Handling Online Reviews independent prescriber, with a special interest
in skin health and mesotherapy. Owner of
Emily Ross outlines key ways to manage online clinic reviews
DermaTops.com, he is now launching his clinic,
Skin Medico, in London.
60 Supporting Your Patient
Deborah Vine highlights the importance of working as a team to enhance NEXT MONTH
patient care • IN FOCUS: Augmentation • Filler Retrospective
• CPD: Lower Eyelid Rejuvenation • Building Your Media Profile
63 Social Media Etiquette
Paul Jackson addresses what practitioners should be aware of when
communicating with patients online
Book your tickets now for
66 In Profile: Dr Zein Obagi
Wendy Lewis talks to Dr Zein Obagi about his journey into aesthetics the Aesthetics Awards 2015
www.aestheticsawards.com
68 The Last Word: Titles and Qualifications
Dr Sam Robson argues for better clarification of titles and qualifications in
medical aesthetics

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Editor’s letter
Finally, some sunshine! It feels deceptively Association of Dermatologists and MET office. The app provides
like summer has arrived as I sit here in the the public with a free daily UV-forecast and suggestions on how
journal office with the sun beating down on best to protect specific skin types. Will you be sharing this new
our backs through the windows. Personally technology with your aesthetic patients?
I love the sun, as those of you who know me It’s not only skin tone and texture that we’ll be exploring in this
Amanda Cameron
will testify. However, the sun has not been as issue. Our CPD article this month focuses on the rejuvenation of
Editor kind to me, and my regrettably sun-damaged the forehead, and provides an extensive overview of this area
skin is the result of summers of abuse in the of the face, looking at the anatomy in detail (p. 27). Dr Maryam
70s with little or no SPF. In those days, factor 2 was considered Zamani presents her technique for rejuvenating the eye area
high, and olive oil gave a much better result in terms of tanning. (p.33), and Dr Renée Hoenderkamp looks at the treatment of acne
If only I knew then what I know now! scarring using dermal filler (p. 39). This month we also profile the
These days there is no excuse for having sun-damaged skin, with infamous Dr Zein Obagi, tracing his journey into aesthetics, and his
increased awareness and high SPF, as well as the improvement subsequent brand expansion (p. 66).
in fake tan for those of our patients who want to be darker. Aside As you will all know by now, entries for the Aesthetics Awards are
from the obvious risk of skin cancer, hyperpigmentation is also now closed. We have been overwhelmed by the quality of the
a very prevalent area of concern in aesthetics, a subject that we written entries, and we look forward to announcing the finalists in
explore in this month’s Special Feature (p. 21). September. In the meantime, we want to hear your thoughts about
One thing is clear, and that is that we do live in a strange and this month’s issue. What are your methods for communicating sun
complex world where half the population want to look darker, safety to your patients? Do you have your own technique for eye
and the other half want to look lighter. Regardless of cultural rejuvenation? Let’s keep up the conversation.
preferences, safety in the sun is key, and this message was Email editorial@aestheticsjournal or tweet us @aestheticsgroup
reinforced with the recent launch of a new UV app from the British #talkaesthetics

Editorial advisory board


We are honoured that a number of leading figures from the medical aesthetic community have joined Aesthetics journal’s
editorial advisory board to help steer the direction of our educational, clinical and business content
Mr Dalvi Humzah is a consultant plastic, reconstructive and Dr Raj Acquilla is a cosmetic dermatologist with over 11 years
aesthetic surgeon and medical director at the Plastic and Derma- experience in facial aesthetic medicine. UK ambassador, global
tological Surgery. He previously practised as a consultant plastic KOL and masterclass trainer in the cosmetic use of botulinum toxin
surgeon in the NHS for 15 years, and is currently a member of the and dermal fillers, in 2012 he was named Speaker of the Year at
British Association of Plastic, Reconstructive and Aesthetic Surgeons the UK Aesthetic Awards. He is actively involved in scientific audit,
(BAPRAS). Mr Humzah lectures nationally and internationally. research and development of pioneering products and techniques.

Sharon Bennett is chair of the British Association of Dr Tapan Patel is the founder and medical director of VIVA
Cosmetic Nurses (BACN) and also the UK lead on the BSI and PHI Clinic. He has over 14 years of clinical experience and
committee for aesthetic non-surgical medical standard. Sharon has been performing aesthetic treatments for ten years.
has been developing her practice in aesthetics for 25 years and Dr Patel is passionate about standards in aesthetic medicine
has recently taken up a board position with the UK Academy of and still participates in active learning and gives presentations
Aesthetic Practitioners (UKAAP). at conferences worldwide.

Dr Christopher Rowland Payne is a consultant Mr Adrian Richards is a plastic and cosmetic surgeon with
dermatologist and internationally recognised expert in cosmetic 12 years of specialism in plastic surgery at both NHS and private
dermatology. As well as being a co-founder of the European clinics. He is a member of the British Association of Plastic and
Society for Cosmetic and Aesthetic Dermatology (ESCAD), he was Reconstructive Surgeons (BAPRAS) and the British Association of
also the founding editor of the Journal of Cosmetic Dermatology Aesthetic Plastic Surgeons (BAAPS). He has won numerous awards
and has authored numerous scientific papers and studies. and has written a best-selling textbook.

Dr Sarah Tonks is a cosmetic doctor, holding dual Dr Maria Gonzalez has worked in the field of dermatology
qualifications in medicine and dentistry. Based in for the past 22 years, dividing her time between academic work
Knightsbridge, London she practices a variety of aesthetic at Cardiff University and clinical work at the University Hospital
treatments. Dr Sarah has appeared on several television of Wales. Dr. Gonzalez’s areas of special interest include acne,
programmes and regularly speaks at industry conferences on dermatologic and laser surgery, pigmentary disorders and the
the subject of aesthetic medicine and skin health. treatment of skin cancers.

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@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Standards

Talk #Aesthetics GMC to develop guidance


for doctors carrying out
Follow us on Twitter @aestheticsgroup
cosmetic procedures
#Psoriasis
The General Medical Council (GMC) has launched a public
Psoriasis Foundation @NPF
People w/mild #psoriasis are just as likely to develop psoriatic consultation on the guidance available to UK-based doctors
#arthritis as those w/ moderate to severe forms of the disease. offering cosmetic procedures. The final guidance, expected to be
#health published in early 2016, will aim to set ethical standards that will be
expected of both surgical and non-surgical UK doctors.
#SPF The GMC hopes the guidance will help patients understand what
Dr Anjali Mahto @DrAnjaliMahto to expect from their doctor and ensure that they undergo cosmetic
Physical #sunscreens reflect UV, chemical sunscreens absorb it
treatments in a safe environment. Key points in the new guidance
#sunprotection #SunSafety #healthyskin
will address, amongst others, the need for doctors to be honest with
patients, ensure doctors market their services responsibly, and give
patients enough time and information before they decide to undergo
a procedure. The GMC is also working with the Royal College of
Surgeons (RCS) of England to publish information about which
surgeons have the right skills to carry out cosmetic surgery.
As the vast majority of cosmetic surgery is currently performed within
the private sector, the law currently allows any qualified doctor to
perform the operations, whether or not they are a trained surgeon,
without any additional qualifications or training. The RCS has already
drafted new standards of training and practice in an attempt to correct
this following the PIP scandal and subsequent Keogh Review. Without
#Training a law in place to give the GMC powers to formally recognise these
Andy Millward @AndyMillward_
qualifications, however, the RCS claim the standards will have limited
Passed assessment & doing my @MARSTE_ACADEMY
Dermagen training with @Marie_Reynolds on June 1st. effect on the industry. The proposed legislation would give the GMC
Needle-ss to say I am extremely excited!! the power to inform both members of the public and prospective
employers which surgeons are qualified to perform cosmetic surgery.
Mr David Ward, consultant plastic surgeon and vice president of the
#NeckLift Royal College of Surgeons, said, “It is very important that the newly
River Aesthetics elected government seizes this opportunity to improve patient safety.
@riveraesthetics
A simple change in the law will allow the General Medical Council
Watching the
Neck lift with Dr to detail whether an individual has the appropriate skills and training
Dorinda Donici from to carry out cosmetic surgery.” Professor Sir Bruce Keogh, NHS
Russia #aesthetics England’s medical director, added, “This consultation is a step in the
@Rosmetics @ right direction to tighten standards and protect people from potential
RealYouClinic risks.” Both the public and practitioners are invited to take part in
the consultation, which runs until September 1. Those interested in
participating can find more information on the GMC website.
#Learning
Sue Ibrahim @SkinSpecialist Skin cancer
With 17 years experience in cosmetic dermatology I have
performed thousands of injectable treatments, but I am still
developing my skills.
Suggested increase in
#Training
melanoma cases
Clare McLoughlin @appearancebased
I’m at the Allergan Master Class 2015 today and tomorrow, New research has indicated that melanoma rates are
with Mauricio de Maio! Look forward to seeing some of you increasing among children and young adults. The research
there too! #allergan indicated that melanoma has increased by more than 250%
among children, adolescents and young adults since 1973.
#Success However, the results also suggest an increase in survival
Dr Tijion Esho @DrTijionEsho rates – from 80% between 1973 and 1980, to 95% in 2011. The
Failure is needed at times of success, it keeps you humble,
surveillance, epidemiology and end results (SEER) data analysed
and that is a quality to maintain while progressing in life
35,762 of melanoma cases, looking at individuals of less than 40
years of age from 1973 to 2011.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Dermal filler Awards

FDA approves dermal filler New sponsors


for hand treatment announced for
The Food and Drug Administration (FDA) has approved the use of dermal filler Aesthetics Awards
Radiesse for volume correction in hand augmentation.
Earlier this year, the FDA Medical Devices Advisory Committee announced a
majority vote of 11 to three in recommending the expanded use of Radiesse
within hand augmentation. Now, the dermal filler, produced by Merz Aesthetics, is
the first to be approved for use in the hand area.
Jim Hartman, vice president and head of US Aesthetics/OTC for Merz North
America told BusinessWire, “Merz is proud to be able to provide patients and
physicians with the first and only dermal filler approved by the FDA for use in the New sponsors have been announced for the
hand.” He added, “This new indication for Radiesse is a result of our focus on Aesthetics Awards 2015. Medical device company
meeting unmet needs in the US aesthetics market, and we are excited to provide Schuco International will now sponsor the Award
our physician customers with this new option to better fulfil the aesthetic desires for Special Achievement, which recognises
of their patients.” the outstanding achievements and significant
Radiesse has been previously FDA approved for the correction of moderate to contribution to the aesthetics profession made by a
severe facial wrinkles and folds. Side effects may include bruising, swelling and particular individual. Previously won by pioneering
redness, which the company state are generally mild and short term. aesthetic practitioner Dr Roy Saleh, this year’s
award will once again celebrate a renowned figure
Skincare in the industry for their dedication to aesthetics.
It has further been announced that Swiss-based
New products launched skincare company Pure Swiss Aesthetics will
sponsor the award for Best Clinic Group UK &
by NeoStrata Ireland (10 clinics or more). This award category
will judge entrants on commitment to excellence
Specialist skincare developer NeoStrata has released in customer services, patient care and patient
new products to join its advanced skincare portfolio.The safety. Teresa Da Graça, chief executive of Pure
new products include Skin Active Dermal Replenishment, and Swiss Aesthetics, said, “Last year’s Aesthetic
Smooth Surface Daily Peel. Awards was Pure Swiss Aesthetics’ introduction to
Skin Active Dermal Replenishment is a night cream, which aims the UK market and that makes our sponsoring this
to deliver optimal hydration and anti-ageing effects for patients year that bit more special.” She added, “We are
with dry skin, using NeoStrata patented technologies that aim to very proud and extremely pleased to be launching
plump, firm and protect the skin. and sponsoring the Best Clinic Group Award with
Smooth Surface Daily Peel is a peel for daily home use, our Swisscode brand.” Entry for the Aesthetics
specifically directed at smoothing fine lines and improving skin Awards 2015 closed on June 30, with the voting
texture. It uses glycolic acid and NeoStrata’s patented Aminofil, process commencing from September 1. The
a tyrosine amino acid derivative (N-Acetyl Tyrosinamide) that awards ceremony will be held on December 5 at
creates a rapid volumising effect, aiming to visibly reduce deep the Park Plaza Westminster Bridge Hotel in London.
facial lines and wrinkles. NeoStrata products are available in the To find out more about the awards, or to book,
UK via AestheticSource. visit www.aestheticsawards.com

Why are Doctors and Nurses switching


T H E A R T O F FA C I A L R E J U V E N AT I O N to VARIODERM HA Dermal Fillers?
• Made in Germany to the highest of standards
• Clinical trials show that it outperforms other major brands for elasticity, longevity
and performance
• Dynamic product range for various indications
• Very competitive pricing
• Very high level of patient satisfaction
Contact info@adareaesthetics.com for further info and pricing.

Adare Aesthetics Ltd, 26 Fitzwilliam Square South, Dublin 2, Ireland.


Mob: +353 (0)85 711 7166 | Tel: +353 (0)1 676 9810
Email: info@adareaesthetics.com | Skype: ivanlawlor | Web: www.adareaesthetics.com
Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015
@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Lips Body contouring

SkinCeuticals introduces Eden Aesthetics to


new lip product distribute new skin
Advanced skincare company SkinCeuticals tightening system
has announced the launch of its new lip
product, Antioxidant (AOX) Lip Complex. Eden Aesthetics
The product, to be released later this month, has acquired the UK
is the latest addition to the company’s distribution rights
‘Correct’ product range. It aims to treat to the Novaestetyc
damaged or ageing lips, with a combination Lift-Shape system.
of pure antioxidants, vitamin E, silymarin and The skin tightening
active ingredients. To be incorporated into a and fractional
daily care routine, SkinCeuticals claims the resurfacing system
AOX Lip Complex delivers three key benefits: aims to improve the
restores hydration, refines and smoothes the appearance of skin
appearance of the lip tissue, and protects through the use of
against environmental damage. Dynamic Quadripolar
It also claims to offer significant benefits when radiofrequency.
offered as part of pre- and post-procedure According to the
care following lip filler augmentation, company, this new
providing relief from common after-effects concept allows the
such as dryness, tightness and swelling. practitioner to focus
“This is a fantastic treatment which I believe the radiofrequency
will quickly become an integral part of my energy where it is
patients’ skincare routine because of how needed most for optimum results. Erika Galtarossa,
it rejuvenates and replenishes lip tissue,” training manager for Novaestetyc, said, “This system
said aesthetic practitioner Dr Sarah Tonks. is based on radio frequency (RF) technology, but it
“AOX Lip Complex delivers an anti-ageing, is a dynamic quadrapolar radiofrequency, which is
protective treatment which I will use in my something specific from us. It means that it is very
clinic both as a preventative option and as effective, but, at the same time, very comfortable to be
an advanced lip therapy for patients with received, and very safe.” Additional handpieces are
premature lip damage.” available to treat larger areas of the body such as the
abdomen, buttocks and thighs.
Botulinum toxin
Technology
Regular Botox may reduce
Consumer gadgets
number of treatments needed
launched to
A study carried out by Dr Alastair Carruthers and his team has revealed that
in patients who regularly received Botox treatments for more than five years, promote sun safety
the time between treatments increased over 22 treatments for glabellar
and crow’s feet lines. The retrospective study looked at data received from The general public are being encouraged to use
multiple centres internationally, covering 194 patients who had received a total gadgets such as mobile apps to protect their skin
of 5,112 Botox treatments. Researchers further found that the average annual from sun. Alongside the Met Office, the British
dose used to treat glabellar lines decreased by 9% as years of treatment Association of Dermatologists (BAD) has produced
increased, with the biggest change happening in the first three years. a mobile app called WORLD UV, which uses GPS
The number of days between Botox injections for glabellar lines went up from technology to calculate local UV levels, and suggest
129 days to 176 days over the course of 22 treatments. For crow’s feet lines, how best users can protect their skin type.
the number of days between treatments also increased from 136 to 209 over In addition, Swedish company Smartsun has
the same period. developed paper wristbands that measure a user’s
Patients further reported positive outcomes, with 98.3% of those aged under UV exposure and changes colour when they need
50 being very satisfied or mostly satisfied with the result of Botox treatment, to reapply sunscreen, while Electronic device
and 86.9% of all patients treated reported looking younger than their actual developer Netatmo has released a bracelet called
age. Dr Carruthers is a consultant for Allergan and has received research JUNE. It communicates with a user’s phone to
grants from the company. The full study, with a full list of disclosures, was recommend adequate SPF and alert users when
published in volume 41, issue 6 of Dermatologic Surgery, in June 2015. they have reached their daily UV limit.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Industry
Vital Statistics
Allergan set to acquire
Kybella manufacturer
Global pharmaceutical company Allergan has announced that it will
acquire Kythera Biopharmaceuticals for $2.1 billion. The news comes
following the recent Food and Drug Administration’s approval of Kybella,
a non-surgical treatment aimed at reducing the appearance of submental
fat, manufactured by Kythera. The acquisition has been agreed as a case 46% of patients use social media
and equity transaction valued at $75 per Kythera share, to be received to look for information about a
as 80% in cash and 20% in Allergan shares, subject to certain customary treatment prior to a consultation
conditions which include the need for approval from Kythera’s stakeholders. (Aesthetic Plastic Surgery)
Brent Saunders, CEO and president of Allergan, said of the news, “The
acquisition of Kythera is a strategic investment that strengthens our leading
global position in aesthetics and continues to position us for long-term Each year,
growth.” The acquisition is subject to expiration or termination of the waiting
54% of the UK
period under the Hart-Scott-Rodino Antitrust Improvements Act 1976. This
states that parties must not complete certain mergers, acquisitions or population is affected
transfers of assets until a detailed filing has been made with the US Federal by skin disease
Trade Commission and the Department of Justice, in order to ensure the (British Association of Dermatologists)
transaction will not adversely affect US commerce under the antitrust laws.
Keith Leonard, CEO and president of Kythera, said, “Allergan’s world-

125 million
class medical aesthetics, global footprint, history and commitment to
developing leading aesthetic products makes them ideally suited to
realise the maximum commercial potential of Kybella.” He continued, “We
An estimated 125 million people
look forward to working with Allergan to ensure a successful US launch of
Kybella, as well as to secure additional approvals globally.” worldwide live with psoriasis
(National Psoriasis Foundation)

Skin cancer

Trial suggests positive outcome 45,506 surgical


procedures were carried
of treating skin cancer with out in 2014
herpes-based drug (British Association of Aesthetic
Plastic Surgeons)

A phase three trial has indicated positive results after a new


herpes-based drug was used to treat skin cancer patients. Dubbed
72% of British people
‘virotherapy’, the new drug, called T-VEC, works by using ‘neutered’ virus
cells to attack the cancer cells, and could become more widely available admitted to being
to cancer patients by next year. sunburned in 2014
More than 400 patients with aggressive melanoma undertook the trial, (British Association of Dermatologists)

which showed one in four had responded to treatment. The trial found
that 16% were still in remission after six months, and 10% of patients
treated had ‘complete remission’ with no detectable cancer remaining.
Members of the control group were treated with a protein designed to
Last year, 44%
of
stimulate the immune response against cancer, but did not include the UK men took steps to
virus component of the treatment. All patients were treated by injection lose weight 44%
and received a dose every two weeks for up to 18 months. (Mintel)
The trial indicated that side effects remained mild compared to
those experienced with chemotherapy drugs, and patients typically
experienced mild flu-like symptoms. Regarding the promising outcome Women under 24 years
of the trial, the authors of the study hope the new drug will offer an
alternative to those with few options.
of age show 45% more
Kevin Harrington, professor of biological cancer therapies at the Institute interest in rhinoplasty than
of Cancer Research London, who led the research, told the Guardian, those between 25 and 34
“This is the big promise of this treatment. It’s the first time a virotherapy (RealSelf)
has been shown to be successful in a phase 3 trial.”

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Events diary Fat reduction

7th – 9th July 2015 SculpSure receives FDA 510(k)


British Association of Dermatologists (BAD)
Meeting, Manchester clearance for non-invasive
www.bad.org.uk/events/annualmeeting
fat reduction
31st July – 2nd August 2015
International Master Course on Aging Skin Medical device manufacturer Cynosure has announced that its hyperthermic
(IMCAS), Asia laser treatment device, SculpSure, has received 510(k) clearance from the
www.imcas.com/en/asia2015/congress Food and Drug Administration for non-invasive fat reduction. The 510(k)
clearance means that the company will now be able to market the device for
19th – 23rd August 2015
the non-invasive treatment of fat. Using a 1060 nm laser with a flexible applicator
American Academy of Dermatology (AAD)
system to treat multiple areas of the body, Cynosure claims the SculpSure system
Summer Meeting, New York
works by disrupting subcutaneous fat cells. “SculpSure represents an entirely
www.aad.org/meetings/2015-annual-
new approach to non-invasive lipolysis, one that is safe and highly effective in
meeting/general-information
reducing adipose tissue and does so in significantly less time than other current
25th – 26th September 2015 treatments,” said Cynosure chairman and CEO Michael Davin.
F.A.C.E2F@ce conference 2015, Cannes
www.face2facecongress.com/en Body countouring

26th September 2015


British College of Aesthetic Medicine
Invasix launches new
Conference, London www.bcam.ac.uk MiniFX application
3rd October 2015
British Association of Cosmetic Nurses Israeli-based medical device company
Conference, Birmingham Invasix Limited has launched its new
www.bacn.org.uk/events/bacn-annual- MiniFX application to expand its multi-
treatment platform, InMode.
conference-exhibition
The new application, now available in
5th December 2015 the UK, will be added to the range of
The Aesthetics Awards 2015, London applications for the InMode system,
www.aestheticsawards.com which aims to allow practitioners to treat
a number of indications on one device.
Invasix claim the new application will allow practitioners to treat smaller and harder
Skincare to reach areas, such as the neck and arms. Like its larger counterpart, BodyFX,
MiniFX is a non-invasive contouring and cellulite treatment which uses four
DMK to introduce technologies; radiofrequency, high amplitude, vacuum and skin temperature. Other
applications for the InMode platform include FRACTORA (for fractional resurfacing
new product range and rejuvenation), FORMA PLUS (for face and body remodelling), LUMECCA (for
internsed pulsed light rejuvenation) and DIOLAZE (for laser hair removal).

Industry

BACN appoints new vice chair


The British Association of Cosmetic Nurses (BACN)
Skincare manufacturer Danné Montague-King has appointed a new vice chair, as aesthetic nurse
(DMK) has announced it will be introducing a new prescriber Lou Sommereux steps down from the
skincare range to its product portfolio. The new position. The BACN has announced that Andrew Rankin,
range, DMK Fundamentals, will include three skincare aesthetic practitioner and trainer, will now take over the
kits: Acne Control, Age Management and Pigment vice chair position.
Balancing. According to the company, the products BACN chair Sharon Bennett said, “Andrew has given
in each kit work to support the skin’s own natural enormous amounts of his time working with HEE and
function. Presented in ‘Home Prescriptive’ packs, with education. He is sensible and balanced, has been
each kit includes a 30-day supply with initial treatment on the board for a number of years and so understands the business and the input
starting in-clinic. Packs include premium DMK required from this demanding, time-consuming position.”
products such as Enzyme masques, Quick peels On taking up his new position, Rankin said, “I am proud to be given this opportunity,
and Fibromax C, with specific products to treat acne, as I am to support Sharon as chair, to work alongside my peers and to represent our
ageing and pigmentation. members so that we can make a difference, which we surely can.”

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

60
Skin cancer

Trial suggests cancer drug


combination could shrink
Roger Bloxham, Managing Director
nearly 60% of melanomas at AesthetiCare
An international trial of 945 people has indicated that taking a combination of The new AesthetiCare adverts
two cancer drugs can have a significant impact on shrinking tumours in patients talk about being ‘Together on
with advanced melanoma. The results of the trial have suggested that treating the journey to better looking
patients with both ipilimumab and nivolumab stopped the cancer from advancing for skin’ and say, ‘Let’s do things
nearly a year in 58% of cases, with tumours either stable or shrinking over a period differently’. What does all this
of 11.5 months. For ipilimumab alone – a product that was approved by the NHS last mean?
year as an advanced melanoma treatment – the figures were 19% and 2.5 months. We are saying that we want to develop a
long-term partnership plan with clinics and
Dr James Larkin, a consultant at the Royal Marsden Hospital and one of the UK’s
practitioners that will really make a difference to
lead investigators, said, “By giving these drugs together you are effectively taking
their clinical and business results, not just in the
two brakes off the immune system, rather than one, so the immune system is able short term, but for years to come. We are also
to recognise tumours it wasn’t previously recognising and react to that and destroy saying that we have the means to do this with
them.” He continued, “For immunotherapies, we’ve never seen tumour shrinkage the comprehensive product range, skin devices
rates over 50% so that’s very significant to see. This is a treatment modality that I and treatments that make up the AesthetiCare
think is going to have a big future for the treatment of cancer.” ‘Aesthetic System Portfolio’, and through the
superior clinical and business support we
Dermal fillers provide. ‘Let’s do things differently’ is a way of
summarising this approach. ‘Together on the
FDA releases safety notice journey to better looking skin’ describes and
defines our collective passion and focus for
on filler injections better looking and healthier skin, and reflects our
strong dermatology and clinical heritage.

The Food and Drug Administration (FDA) has published a safety What is the AesthetiCare ‘Aesthetic System
communication in relation to the unintentional injection of soft tissue fillers Portfolio’, mentioned above?
into facial blood vessels. After reviewing information that suggests unintentional This is the portfolio of medigrade skincare and
injection of soft tissue fillers into blood vessels in the face can result in rare, skin devices and treatments that we are constantly
but serious, side effects, the FDA are now urging practitioners, and those working on developing and assembling. The
contemplating filler treatment, to be aware of the risks. Risks can include AesthetiCare focus is always on evidence base
blocking of blood vessels, resulting in embolisation, visual impairment, strokes and technologies and formulations that deliver
and necrosis. It can also cause damage to underlying facial structures. The FDA high-level clinical results. When it comes to skin the
portfolio addresses the majority of the needs of an
has advised practitioners to thoroughly warn patients of the risks associated
aesthetic skin clinic, and crucially, the products and
with treatment, and to ensure that they are aware of any signs and symptoms
devices all complement each other, and can be
associated with injection into blood vessels, with a detailed plan for adverse used in evidence-based synergistic combinations
reactions. Following the review, the FDA is working with manufacturers to update to deliver fantastic results.
their labelling with additional warnings, precautions and other statements about
the risk of unintentional injection into blood vessels. What’s the main focus and which indications
does the portfolio combat?
Industry The focus is always better looking and healthier
skin. The indications are rejuvenation of aged
Ferndale Pharmaceuticals and photo-damaged skin, prevention of the
acceleration of skin ageing and providing
and Aesthetic Technology resolution to skin problems such as acne, acne
scars, pigmentation, rosacea / red and flushed
strengthen collaboration skin. We also, through individual technologies
and combinations, provide great enhancement
to lax and sagging skin, including body shaping
Ferndale Pharmaceuticals has acquired 30% of Aesthetic Technology shares in a and inch loss. This breadth and synergy enables
joint commercial venture. Aesthetic Technology is the developer and manufacturer us to truly consult and build long-term clinical and
of the Dermalux LED phototherapy systems, whilst Ferndale Pharmaceuticals is a business partnership.
specialty dermatology company. Upon the collaboration, Dermalux will be integrated
This column is written and supported by
into AesthetiCare, Ferndale’s aesthetic division, with the aim of Aesthetic Technology
expanding into the professional beauty and spa sectors. The companies hope that
Ferndale can provide Aesthetic Technology with enhanced financial strength and
operational infrastructures, particularly with its developing international presence.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Skincare
News in Brief
AesthetiCare launches new Harley Street doctor offers eight-
hour lip filler treatment
product range Aesthetic practitioner Dr David Jack is
offering patients a lip-plumping procedure
that lasts six to eight hours.
Instead of injecting traditional filler, Dr Jack
injects saline solution to the surrounding
area of the lips to produce shorter-term
results. According to reports, the treatment,
dubbed ‘Cinderella Lips’, is becoming
popular amongst people seeking temporary
lip enhancements before committing to
traditional lip fillers.

Waterhouse Young appoints new


doctor to join team
Aesthetic practitioner Dr Saira Vasev has
Skincare and device manufacturer AesthetiCare has launched BiRetix, a new joined the team of clinical staff at the non-
cosmetic range geared at treating spot-prone skin. Included in the range is BiRetix surgical aesthetic practice, Waterhouse
Duo, which contains RetinSphere Technology, (a combination of cosmetic retinoids Young. Previously, Dr Vasdev has
that aim to clear pores and clarify skin. It also contains BOIPEP.15, a botanical complex worked for the NHS where she studied
with Oligopeptide 10, a bioactive peptide containing naturally occurring amino acids recovery procedures for facial injuries. A
to fight P. acnes, and salicylic acid. According to the company, clinical studies have spokesperson for Waterhouse Young stated
indicated that each ingredient works to improve the appearance of comedones, that Dr Vasdev has proven to be a valuable
spots and redness. The BiRetix Micropeel and BiRetix Mask are also included in the member of the team and feedback from her
skincare range. The Micropeel contains a clarifying and exfoliating cleanser with first clients has been exceptional.
botanical extracts and exfoliants that aim to clear pores and stimulate cell renewal,
while the clay mask contains mineral, anti-oxidants and RetinSphere technology, EF MEDISPA opens in Canary Wharf
which aim to control sebum and reduce shine. The new range is part of the Resolve Aesthetic clinic chain EF MEDISPA is set
category of AesthetiCare’s SKINSYNERGY medi-grade skincare portfolio, which also to open its fourth London clinic in Canary
includes products for treating pigmentation and redness. Wharf later this year. The new clinic, which
will be situated on Admiral’s Way, will open
Skincare in August and aim to offer patients the latest
advances in medical aesthetics, with a
AestheticSource announced as particular ethos to cater to Canary Wharf’s
time-short executives. The company’s
headline sponsor for ACE 2016 current clinic portfolio includes clinics in
Kensington, Chelsea and St John’s Wood.
Skincare distributor AestheticSource
has been announced as the official Irwin Mitchell launches new
headline sponsor for the Aesthetics cosmetic tracker app
Conference and Exhibition (ACE) 2016. Specialist cosmetic surgery lawyers at
Following its success as the headline Irwin Mitchell have developed an app
sponsor at ACE 2015, the company that assists those going through cosmetic
is now looking forward to next year’s procedures to track their journey. The new
premium UK aesthetic conference event. app, ‘BeautyTracker’, allows patients to
“AestheticSource are proud to be the headline sponsor at the Aesthetics Conference track their journey with practitioners and
and Exhibition 2016,” said Lorna Bowes, director of AestheticSource. “This year’s clinics in an attempt to improve safety in the
conference was a real success for our team, and we look forward to returning industry, following a rise in patients affected
in 2016 as we take on the headline sponsorship once again.” She added, “The by negligent treatments. Allowing patients
conference always provides fantastic exposure for AestheticSource, and the to keep a log of treatments and details of
extensive agenda really supports our view of the importance of ongoing education practitioners, the app will further provide
within the aesthetic industry. We can’t wait to see what next year’s event will bring to access to expert advice if a treatment goes
the educational table!” ACE 2016 will feature a broad agenda, with in-depth clinical wrong. Users will also be able to access
content on the latest innovations, best practice, advice and demonstrations from independent sources of help and advice
leading professionals in the aesthetics industry. To keep up to date with all the if they have an unsatisfactory outcome
latest announcements regarding Aesthetics events, sign up to receive our weekly following treatment.
e-newsletter at www.aestheticsjournal.com

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Botched Bodies and Cosmetic


Surgery Cowboys: The representation
of aesthetics in mainstream media
Aesthetics explores the prevalence of negative
reporting on our industry, and talks to media
professionals about how it can be improved
Introduction
‘Trout pout’, ‘pillow face’ and the ‘Bride of Wildenstein’ are all terms to maintain, defines the public interest as including, but not being
synonymous with the representation of medical aesthetics in the confined to:2
media. Type ‘cosmetic surgery’ into any search engine and results
generate news of celebrity treatments, botched procedures and, at • Detecting or exposing crime or serious impropriety.
worst, death following surgery. While ‘scare stories’ can of course • Protecting public health and safety.
encourage the public to think carefully about the risks of procedures • Preventing the public from being misled by an action or statement
and the importance of seeking treatment from a safe practitioner, some of an individual or organisation.
aesthetic professionals argue that they can have a negative impact on
the industry. Many practitioners are also quick to criticise the reporting With such a prominent lack of regulation and a high prevalence of
of potentially unsafe treatments and procedures, which often have little un-qualified practice taking place in the UK, it is inevitable that the
to no safety data supporting their use as aesthetic treatments. Stories aesthetic and cosmetic industry ticks the ‘public interest’ box, and
derived from clinical studies can be exaggerated and sensationalised, captures the attention of the media.
claiming new cures and promising immediate, pain-free aesthetic
results. So who is to blame for these hyped-up stories? Many are Misreporting
quick to point the finger at newspapers, competing for sales figures “We are contacted by PRs on a daily basis,” explains Barney Calman,
and desperate to win the widest readership. Yet the two journalists health editor of the Mail on Sunday. “We have to treat everything with
interviewed for this report highlight the challenges of deciphering caution – our journalists always request studies, safety data and the
scientific jargon and the need for more support from the aesthetics proof that something works before writing about it,” he says. Calman
and cosmetic surgery industries to secure accurate reporting. In this, exemplifies one case in which a journalist on his team was sent a
public relations officers (PRs) and the academics approving scientific press release announcing that a particular brand of lip filler could now
press releases have an important role to play. Research published be used for vaginal rejuvenation. “The reporter had done her due
in the British Medical Journal suggests that exaggeration in news is diligence and asked for safety data, which they had sent to her. The
strongly associated with exaggeration in press releases. The study has filler had received a CE mark based on the fact it is safe to be used
indicated that 40% of press releases on biomedical and health-related in the body, however there was certainly nothing to note that it was
science contain exaggerated advice, 33% contain exaggerated casual indicated for use in that area,” he explains. “It turned out there was
claims, and 36% contain exaggerated inference to humans from nothing to support its safety for vaginal rejuvenation.”
animal research.1 Calman notes that following 11 years of reporting healthcare news,
Mr Rajiv Grover, plastic surgeon, former president of the British he is now adept at spotting anything untoward. “But obviously, if we
Association of Aesthetic Plastic Surgeons (BAAPS) and member are lied to or misled then incorrect or unsafe information can get out
of the BAAPS press committee, also notes that it is important that there,” he says.
practitioners take some of the responsibility for the amount of
undesirable stories in the media. He says, “Those negative stories The Value of PR
didn’t just come out by accident – there have been negative things It is common practice for both aesthetic organisations and individual
happening. It’s important that we have high standards everywhere practitioners to employ the support of PR officers to promote their
so there’s less negativity to report.” As such, it seems apparent that services and spread their messages within the media. Julia Kendrick
aesthetic professionals, PRs and media representatives need to work has recently established her self-titled PR consultancy business
together to improve the representation of aesthetics and cosmetic following years of representing large pharmaceutical companies.
surgery in the media, but how can this be done effectively? To minimise the risk of sharing misleading press releases, Kendrick
ensures anything she sends out is to a pharmaceutical standard. “The
The Public Interest companies I work with are focused on ensuring that all material they
‘If it bleeds, it leads’ is an old adage adopted by many media outlets send out is extremely accurate, well referenced, and adheres to the
to explain the sales value of a negative news story in comparison to a standards set out by the ABPI,” she explains. The Association of the
positive one. Despite many people’s objection to this approach, it does British Pharmaceutical Industry (ABPI) Code of Practice sets standards
provide an explanation as to why so much aesthetic and cosmetic for promoting appropriate use of medicine to the public. It states that,
surgery news focuses on the undesirable results and negative “Companies must ensure that their materials are appropriate, factual,
connotations associated with the industry. Along with this, journalists fair and capable of substantiation and that all other activities are
are obliged to report stories that are ‘within the public interest’. The appropriate and reasonable.”3
Editors’ Code of Practice, which all members of the press have a duty Kendrick encourages her clients and other PR companies to adopt

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

this approach and suggests that, “If you’re conducting yourself and individual practitioners looking to enhance their public profile. Kendrick
your business to the highest possible standards in the industry, you’re shares some of her best tips for talking to journalists:
setting yourself up in a way that’s going to be successful, credible
and ethical.” While ensuring the accuracy of the content you share • Don’t get drawn into sensationalism; avoid commenting on
is essential, it is sometimes beneficial to inject some fun into press rumours, you’ll only fuel the fire.
releases, suggests Tingy Simoes, especially when fighting for news • Use your own expertise to provide a balanced perspective on the
space amongst negative reports. Mr Grover agrees, “Journalists in topic in question.
mainstream media are getting hundreds of press releases per day. • Research the journalist’s background and publication prior
Unless you make it interesting for them and stand out, there’s no to interview; consider who they are, their specialty, who the
reason for them to read it because they have no time.” publication’s audience is, the tone of the publication, and what you
As the managing director of Wavelength Marketing Communications expect the journalist is looking for.
and Cacique Public Relations, Simoes is known amongst journalists • Avoid talking in jargon and acronyms – Albert Einstein once said,
and practitioners for her eye-catching email subject lines and inventive “If you can’t explain it simply, you don’t understand it well enough”.
treatment captions. She’s coined phrases such as, ‘The Miami Thong Modify your response so that it’s appropriate to the journalist, the
Lift’, which she says generated international press coverage, and media outlet and the readership.
‘The Smile Transplant’, which refers to the treatment available to facial
palsy sufferers. Associating the phrase with the news that the NHS Kendrick explains that she hopes these methods will improve the
wasn’t routinely funding ‘smile transplants’4 garnered a hugely positive standard of communication needed between the aesthetics world
response from the UK media, according to Simoes. “If you give and the media. Aidin adds that a practitioner who can explain things
something a name that people can automatically understand and tie well is invaluable to her reporting. She says, “I’ve learnt a lot from
it to something current, you’ll get something that’s very well respected certain practitioners who are intelligent and great communicators; it’s
and sometimes makes global news,” she explains. From a journalist’s very important.”
perspective, Calman adds, “There’s certainly a harmonious respect
to be had – if PRs come up with fun ways of selling things, and can Looking Forward
project a treatment onto a fun theme, then it can often work really well While the aesthetic industry remains severely lacking in regulation, and
in terms of selling a page.” Simoes also highlights the importance of manufacturing companies continue to innovate and create, it seems
PR officers understanding the topic they are trying to promote to the unlikely that the media storm surrounding our industry will die down
media. “I find it sad that some PR agencies are cheapening aesthetics any time soon. As a journalist, Calman argues that it is not the job of
by not understanding it,” she says, adding, “I work so hard on our media professionals to police the industry. “We’re not medical experts,”
press releases, ensuring all the information is in there; statistics, detail, he says. “We’re reporters, and our job is to translate information
layman’s terms – we’re trying to educate people and find the things we receive into a format the can be readily understood by our
that are fascinating about the industry.” Freelance journalist Beatrice readers.” In addition, any journalist can be taken to the Independent
Aidin agrees, noting that she deletes any ambiguous press releases Press Standards Organisation (IPSO), an independent regulator
she receives. “PRs have a tough job to do, especially in terms of of the newspaper and magazine industry, and reprimanded for a
medical PR. I think, though, that if the PRs haven’t understood the story, breach of the Editors’ Code.5 Calman says, “We take the code very
how will I? If they don’t know what they’re talking about I have no faith seriously and make all of our journalists attend IPSO seminars on their
I’m going to get something accurate.” Calman adds, “I wouldn’t like to responsibilities of reporting accurately and not distorting the facts.”
blame PR officers because they’re simply working with the information Kendrick notes that you’re never going to be able to chase down
that they’re given. Their job is to have connections with journalists, not and correct every sensationalist story. As a press officer, she says the
to be medical experts.” importance lies in communicating at the highest possible standard with
the aim of minimising the risk of inaccurate reporting. “It’s about having
Improvement Strategies the trust and relationship to follow up with journalists if there’s anything
Mr Grover explains that the BAAPS has recently formed an majorly wrong – it ultimately benefits their reputation, as well as
organisation called the National Institute of Aesthetic Research (NIAR) provides consumers with accurate information.” Mr Grover highlights
to address the lack of data on the efficacy and safety of aesthetic and the work of associations such as the British College of Aesthetic
cosmetic surgery treatments. Working in association with the Healing Medicine and the British Association of Cosmetic Nurses, which are
Foundation, a charity that supports people living with disfigurement regularly campaigning for higher standards of regulation within the
and visible loss of function, Mr Grover explains that the BAAPS hopes industry. To conclude, he reiterates his first point; “It’s important that we
the NIAR can investigate areas lacking research and produce reliable have high standards everywhere, so there’s less negativity to report.”
data to be shared with the public. He says, “Although the institute’s in
REFERENCES
its infancy, it will hopefully gain the trust of the media and inform the 1. The association between exaggeration in health related science news and academic press
releases: retrospective observational study (UK: British Medical Journal, 2014) <http://www.bmj.
public of aesthetic developments in an appropriate way.”
com/content/349/bmj.g7015>
The fast-paced nature of news also means that the industry 2. Editors’ Code of Practice (UK: Independent Press Standards Organisation, 2015) <https://www.
ipso.co.uk/IPSO/cop.html>
needs to act quickly to comment on breaking stories and provide
3. Code of Practice for the Pharmaceutical Industry (UK: Association of the British Pharmaceuti-
knowledgeable and reliable explanations or opinion. As Calman cal Industry, 2015) <http://www.abpi.org.uk/our-work/library/guidelines/Documents/code_of_
4. practice_2015.pdf4>
explains, even journalists who specialise in healthcare reporting are
5. Rebecca Smith, Smile transplants for stroke sufferers ‘not routinely funded’ by NHS (UK: The
not likely to be medically trained, let alone journalists working within Telegraph, 2012) <http://www.telegraph.co.uk/news/health/news/9683290/Smile-transplant-for-
stroke-sufferers-not-routinely-funded-by-NHS.html>
a different specialty, leaving clinical studies and press releases open
6. About IPSO (UK: Independent Press Standards Association, 2015) <https://www.ipso.co.uk/
to interpretation. Being able to help journalists in their enquiries as IPSO/index.html>
soon as possible is beneficial to the industry as a whole, as well as for

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


COMPOSED • CONFIDENT • MY CHOICE

PURIFIED1• SATISFYING2,3,4 • CONVENIENT5

Now approved for


crow’s feet lines

Bocouture® 50 Abbreviated Prescribing Information Please refer to the Summary of Product dry eye. General disorders and administration site conditions; Common: injection site haemotoma.
Characteristics (SmPC) before prescribing. 1162/BOC/AUG/2014/PU Presentation 50 LD50 units of Post-Marketing Experience; Flu-like symptoms and hypersensitivity reactions like swelling, oedema
Botulinum toxin type A (150 kD), free from complexing proteins as a powder for solution for injection. (also apart from injection site), erythema, pruritus, rash (local and generalised) and breathlessness
Indications Temporary improvement in the appearance of moderate to severe vertical lines between have been reported. Overdose May result in pronounced neuromuscular paralysis distant from the
the eyebrows seen at frown (glabellar frown lines) and lateral periorbital lines seen at maximum smile injection site. Symptoms are not immediately apparent post-injection. Bocouture® may only be used
(crow’s feet lines) in adults under 65 years of age when the severity of these lines has an important by physicians with suitable qualifications and proven experience in the application of Botulinum
psychological impact for the patient. Dosage and administration Unit doses recommended for toxin. Legal Category: POM. List Price 50 U/vial £72.00 Product Licence Number: PL 29978/0002
Bocouture are not interchangeable with those for other preparations of Botulinum toxin. Reconstitute Marketing Authorisation Holder: Merz Pharmaceuticals GmbH, Eckenheimer Landstraße 100,
with 0.9% sodium chloride. Glabellar Frown Lines: Intramuscular injection (50 units/1.25 ml). 60318 Frankfurt/Main, Germany. Date of revision of text: August 2014. Further information
Standard dosing is 20 units; 0.1 ml (4 units): 2 injections in each corrugator muscle and 1x procerus available from: Merz Pharma UK Ltd., 260 Centennial Park, Elstree Hill South, Elstree, Hertfordshire
muscle. May be increased to up to 30 units. Injections near the levator palpebrae superioris and WD6 3SR.Tel: +44 (0) 333 200 4143
into the cranial portion of the orbicularis oculi should be avoided. Crow’s Feet lines: Intramuscular
injection (50units/1.25mL). Standard dosing is 12 units per side (overall total dose: 24 units); 0.1mL Adverse events should be reported. Reporting forms and information can be found at
(4 units) injected bilaterally into each of the 3 injection sites. Injections too close to the Zygomaticus www.mhra.gov.uk/yellowcard Adverse events should also be reported to Merz Pharma UK Ltd at
major muscle should be avoided to prevent lip ptosis. Not recommended for use in patients over the address above or by email to medical.information@merz.com or on +44 (0) 333 200 4143.
65 years or under 18 years. Contraindications Hypersensitivity to Botulinum neurotoxin type A or to
any of the excipients. Generalised disorders of muscle activity (e.g. myasthenia gravis, Lambert-Eaton 1. Bocouture 50U Summary of Product Characteristics. Bocouture SPC 2014 August available from:
syndrome). Presence of infection or inflammation at the proposed injection site. Special warnings URL: http://www.medicines. org.uk/emc/medicine/23251.
and precautions. Should not be injected into a blood vessel. Not recommended for patients with 2. Prager, W et al. Onset, longevity, and patient satisfaction with incobotulinumtoxinA for the
a history of dysphagia and aspiration. Adrenaline and other medical aids for treating anaphylaxis treatment of glabellar frown lines: a single-arm prospective clinical study. Clin. Interventions in
should be available. Caution in patients receiving anticoagulant therapy or taking other substances in Aging 2013; 8: 449-456.
anticoagulant doses. Caution in patients suffering from amyotrophic lateral sclerosis or other diseases 3. Sattler, G et al. Noninferiority of IncobotulinumtoxinA, free from complexing proteins, compared
which result in peripheral neuromuscular dysfunction. Too frequent or too high dosing of Botulinum with another botulinum toxin type A in the treatment of glabelllar frown lines. Dermatol Surg 2010;
toxin type A may increase the risk of antibodies forming. Should not be used during pregnancy unless 36: 2146-2154.
clearly necessary. Should not be used during breastfeeding. Interactions Concomitant use with 4. Prager W, et al. Botulinum toxin type A treatment to the upper face: retrospective analysis of
aminoglycosides or spectinomycin requires special care. Peripheral muscle relaxants should be used daily practice. Clin. Cosmetic Invest Dermatol 2012; 4: 53-58.
with caution. 4-aminoquinolines may reduce the effect. Undesirable effects Usually observed within 5. Data on File: BOC-DOF-11-001_01
the first week after treatment. Localised muscle weakness, blepharoptosis, localised pain, tenderness,
itching, swelling and/or haematoma can occur in conjunction with the injection. Temporary vasovagal Bocouture® is a registered trademark of Merz Pharma GmbH & Co, KGaA.
reactions associated with pre-injection anxiety, such as syncope, circulatory problems, nausea or 1183/BOC/DEC/2014/DS Date of preparation: December 2014
tinnitus, may occur. Frequency defined as follows: very common (≥ 1/10); common (≥ 1/100, < 1/10);
uncommon (≥ 1/1000, < 1/100); rare (≥ 1/10,000, < 1/1000); very rare (< 1/10,000). Glabellar Frown
Lines: Infections and infestations; Uncommon: bronchitis, nasopharyngitis, influenza infection. PURIFIED1• SATISFYING2,3,4 • CONVENIENT5
Psychiatric disorders; Uncommon: depression, insomnia. Nervous system disorders; Common:
headache. Uncommon: facial paresis (brow ptosis), vasovagal syncope, paraesthesia, dizziness.
Eye disorders; Uncommon: eyelid oedema, eyelid ptosis, blurred vision, blepharitis, eye pain. Ear
and Labyrinth disorders; Uncommon: tinnitus. Gastrointestinal disorders; Uncommon: nausea, dry
mouth. Skin and subcutaneous tissue disorders; Uncommon: pruritus, skin nodule, photosensitivity,
dry skin. Musculoskeletal and connective tissue disorders; Common: muscle disorders (elevation of
eyebrow), sensation of heaviness. Uncommon: muscle twitching, muscle cramps. General disorders Botulinum toxin type A
and administration site conditions; Uncommon: injection site reactions (bruising, pruritis), tenderness,
Influenza like illness, fatigue (tiredness). Crow’s Feet Lines: Eye disorders; Common: eyelid oedema, free from complexing proteins
aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Meet the Expert to Expert


Experts Day, London
Evening, Featuring live
demonstrations,
London lectures and Q&A
sessions, Lifestyle
Skincare distributor Aesthetics hosted
AestheticSource hosted its Expert to Expert
a ‘Meet the Experts day at the Royal
Evening’, chaired Society of Medicine
by dermatologist Dr in London on May 30.
Sandeep Cliff, at the Royal Society of Medicine in London on June 3. Professor Delegates were invited
Beth Briden, medical director and CEO of the Advanced Dermatology and to a variety of talks with aesthetics practitioners
Cosmetic Institute in Minnesota, began the sessions by detailing new active from across the industry, discussing techniques for
ingredients in skincare, and introduced new products from skincare specialists facial rejuvenation. Aesthetic practitioner Dr Fabio
NeoStrata. Dr Uliana Gout, chairperson of the International Chemical Peel Society, Ingallina began the sessions with a discussion
then addressed the need for evidence-based skincare, which was followed by on understanding anatomical landmarks for facial
dermatologist Dr Mukta Sachdev’s presentation on the importance of pre-peel rejuvenation, which was then followed by dental
preparation in order to avoid pigmentation issues in skin of colour. surgeon Dr Lee Walker, who demonstrated effective
To conclude the presentations, Dr Stefanie Williams discussed the effects of ways of contouring the lips and perioral area with
sugar on skin. She advised practitioners to urge patients to monitor their starch Teoxane’s Teosyal Pen. Later in the afternoon,
intake – a major contributor of sugar in food – and highlighted that those with delegates were able to question the expert panel,
diabetes appear to age quicker. “It was a very, very good evening,” said attendee with renowned practitioner Dr Tracy Mountford
and aesthetic practitioner Dr Jamshed Masani, following the final Q&A session. acting as moderator for the event. Of the day, Sue
“Especially Dr Mukta Sachdev’s lecture on skin of colour, how she handles Wales, co-founder of Lifestyle Aesthetics, said, “It is
peels with pre-peel regimes, and then doing the peels and still getting good inspiring to see so many experienced practitioners
results. We in Britain are so frightened to treat skin of colour for the reasons of turning out on a Saturday to gain more tips from our
hypopigmentation and hyperpigmentation.” experts.”

FACE, London Proof in Real


Life Reveal,
Berlin
The treatment of 10 identical twins was announced as the secret behind
Galderma’s Proof In Real Life campaign at the Reveal event in Berlin on May
The Facial Anti-Ageing Conference and Exhibition (FACE) 28. One sibling from each pair of twins had been treated with both Restylane and
was held from June 4-6 at the Queen Elizabeth II Centre, Restylane Skinboosters, or just one of the products, with the aim of demonstrating
London. Throughout the weekend, attendees were invited natural-looking results achieved through aesthetic treatment. Global
to lectures on anti-ageing concerns of the face. Topics pharmaceutical company Galderma created the Proof In Real Life campaign with
covered the likes of sun protection, treating blonde/white the hope of challenging misconceptions that aesthetic treatments create extreme
hair and pigmentation. The event also incorporated the results. Actress Sharon Stone was announced as the global ambassador for the
annual BODY Conference into its programme, with one campaign at the Aesthetic & Anti-Aging Medicine World Congress in March, and
session by aesthetic practitioner Dr Uliana Gout discussing later hosted the Reveal event alongside plastic surgeon Mr Per Hedén, who
hand rejuvenation procedures and the importance of careful detailed how the patients had been treated. In her opening speech, Stone said,
injecting for this area. On Saturday afternoon, Dr Stefanie “Tonight’s a very special night, not just for Galderma, but for the world of beauty.
Williams joined the programme to demonstrate medical We all know that the aesthetic world is famous for showing extreme looks and
needling with PRP, offering key advice on procedure images of aesthetic treatments, which, as many of us know, are not true. The
protocol to ensure optimal results. Andrew Morris, country only way to change this perception is to be bold and to be honest.” The sets of
operations manager for Sinclair Pharma, said, “The FACE twins were welcomed to the stage to showcase their results and, following the
conference was very busy for Sinclair with lots of interest Reveal, mingled with guests to discuss their experiences. Dr Kuldeep Minocha,
in Silhouette Soft and ELLANSÉ, particularly in their lead aesthetic practitioner at Absolute Aesthetics in London, treated all but two
combination use. There was standing room only at our sets of the twins. He said, “We worked with the individuals as I would in a normal
training workshops which reinforces Sinclair’s commitment consultation – it was important to me to treat the participants like any other patient.
to quality training.” It’s a very unique campaign and it’s been quite amazing to see the results.”

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Colour me youthful:
the problem with
hyperpigmentation
Sun damage, hormones, inflammation – the
causes of hyper-pigmented skin are almost as
numerous
numerousas asthe
thetreatments
treatmentsononoffer
offerto
tocorrect
correctit.
it.
Allie Anderson talks to practitioners to find out how
to
todeal
dealwith
withthe
thecommon
commonaesthetic
aestheticconcern
concern
If there’s one presentation in the world of medical aesthetics associate hyperpigmentation with the health of their skin. “Patients
that continues to challenge practitioners, it’s hyperpigmentation. come to see me because they’ve reached a point in their lives
Yet, evidence suggests that patients are increasingly seeking when they’re bothered by hyperpigmentation,” Miss Balaratnam
consultation and treatment for the problem. “Whether that’s because adds. For example, someone with many freckles on their face
it’s become a bigger issue, or that it’s always been there but people (caused by increased melanin) may perceive them to be attractive
haven’t been seeking advice from private medical professionals in youth, but less appealing with age. Similarly, dark liver spots on
before, I’m not sure,” remarks Dr Simon Ravichandran, founder of the face may be no cause for concern for one person, and be very
the Clinetix Medispa group. Whatever the reason, he reports that distressing for someone else. Many practitioners, therefore, assess
pigmentation treatments account for around 10-15% of his clinics’ hyperpigmentation not in terms of how severe it is, but the degree to
patient cohort. which it affects the patient.

Cause and effect Measures of severity can be useful, though. Dr Ravichandran uses
Hyperpigmentation – or hyperpigmentation disorders – are caused by the Melasma Area and Severity Index (MASI), which uses a formula
overproduction of melanin by the pigment cells, called melanocytes, to calculate an overall score of severity based on the practitioner’s
and less commonly, by a greater number of melanocytes.1 The assessment of:
umbrella term ‘melasma’ is often broadly used to describe
hyperpigmentation disorders of unknown aetiology, associated with 1. The extent of coverage on four areas of the face (forehead, left
hormonal changes (including pregnancy), certain medications and cheek region, right cheek region and chin), each given a score of
sun exposure. Additionally, increased pigment can be caused by 0 to 6 based on percentage coverage.
post-inflammatory hyperpigmentation (PIH), such as that left by acne 2. Darkness of the hyperpigmentation, where 0 is absent and 4 is
scarring, psoriasis, and previous aesthetic treatments. maximum.
Exposure to sunlight triggers melanin production in order to protect 3. Homogeneity of the hyperpigmentation, using the same scale as
the skin from harmful ultraviolet (UV) rays.2 Excessive sun exposure the darkness measure.4
results in increased melanin production, making sun exposure
a major cause of hyperpigmentation. Accordingly, practitioners The usefulness of the MASI score has been disputed on the basis that
report that patients presenting with UV-induced hyperpigmentation it is wholly subjective, but a 2009 study published in the Journal of the
tend to be in their 40s and 50s, having spent many years tanning, American Academy of Dermatology found it to be a reliable and valid
much of that time ill-informed about the risks associated with measure of melasma severity.5 It also serves as a useful evaluation of
sun exposure and sunbeds. Patients seeking treatment for treatment outcomes and improvements, says Dr Ravichandran.
hyperpigmentation more generally range in age from early 30s to According to Aysha Awwad, director of Medico Beauty, many patients
late 50s, with more than 90% of cases occurring in women.3 are concerned specifically about premature ageing, focusing on the
appearance of wrinkles rather than uneven pigment. She uses the
Subjective assessment Glogau Photo-damage and Ageing Skin Scale (also known as the
Miss Sherina Balaratnam, medical director of S-Thetics clinic Glogau Wrinkle Scale) to determine a patient’s ‘ageing skin type’. This
and a former NHS trainee plastic surgeon, comments, “Younger is determined by the grade of photo-ageing, which is skin damage
patients – even in their 20s – have less advanced skin damage, primarily visible in the form of discolouration and wrinkles, and which
but they’re more conscious of it from an appearance point of view.” develops at different ages depending on the degree of exposure
That, she says, is owing to greater appreciation among younger to UV light.6 The scale is used to ascertain which treatments and
patients of the dangers of UV damage, which in turn leads them to products match the patient’s skin type and needs.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Figure 1: Glogau Photo-damage and Ageing Skin Scale7

Type Description Patient age Indicators

Type 1 Early wrinkles 20s to 30s • Early photo-ageing


• Mild pigment changes
• Minimal wrinkles
• No age spots

Type 2 Wrinkles in motion 30s to 40s • Early to moderate photo-ageing


• Appearance of smile lines
• Early brown age spots
• Skin pores more prominent
• Early changes in skin texture

Type 3 Wrinkles at rest 50s and older • Advanced photo-ageing


• Prominent brown pigmentation
• Visible brown age spots
• Small blood vessels and wrinkles, even at rest

Type 4 Only wrinkles 60s and 70s • Severe photo-ageing


• Yellow-grey skin colour
• Prior skin cancers
• Pre-cancerous skin changes (actinic keratosis)

Treatments and techniques Laser therapy for hyperpigmentation


Hyperpigmentation treatments fall into three main groups: topical Lasers are commonly the last line of defence against
agents, peels and lasers. Triple-combination topical therapy hyperpigmentation, but some practitioners offer laser/light-
comprising hydroquinone, tretinoin (a prescription-strength retinoic based treatment routinely. At River Medical in Ireland, the Fraxel
acid) and a corticosteroid has been found in a number of studies to Dual 1550/1927 laser is used in patients with prematurely aged
be most effective in treating melasma.8,9 Indeed, Dr Ravichandran and sun-damaged skin. After a topical anaesthetic cream has
describes this as “the gold standard”, and it is his preferred first-line been left on the skin for 45 minutes, the laser is applied, with
treatment. Miss Balaratnam also opts for hydroquinone to inhibit treatment taking just 20-40 minutes. “The melanocytes down on
tyrosinase (which causes melanin cells to become more active), the epidermal/dermal junction grow out like branches of a tree,
along with tretinoin “to help drive the product deeper into the which appear as freckles or pigmentation on the skin’s surface,”
cellular layers in order to target deeper discoloration.” This follows business manager Aileen Gillic explains. “So the source of the
a Visia Skin Consultation imaging session to analyse a number of problem is not always directly beneath the area of pigmentation
contributors’ complexion health and appearance, including UV spots – it might be 5-6cm away. For that reason, a full treatment to
that indicate sun damage, skin tone variation, pore size and wrinkles. the whole area (the entire face, décolletage or hand) – rather
The results may also indicate exfoliation with a cosmeceutical such than just to the pigmented spots – is absolutely necessary.” Side
as alpha hydroxyl acid (AHA), forms of which are beneficial in treating effects of the 1550 and 1927 nanometre light wavelengths include
PIH and melasma.10 redness and swelling immediately after treatment, with a dry and
flaky skin appearance for up to 14 days. “It’s not proper clinical
Retinoids, such as retinoic acid, have been shown to be effective in downtime, but it’s social downtime,” Ms Gillic adds.
treating PIH,11 but can cause skin irritation. A kinder alternative is the
non-prescription vitamin A derivative retinaldehyde, which is well
tolerated.12 Awwad chooses this in a topical formulation, claiming
it’s gentler than skin-bleaching agents like hydroquinone. “We don’t Chemical peels in various
want to bleach the pigment out of the skin [with hydroquinone];
we want to understand why the melanocytes are behaving in the formulations are employed
way they are, and regulate their behaviour,” she says. Her clinic’s
treatment protocol also incorporates layered topical treatments by some practitioners
applied after deep cleansing of the skin, using a Forao sonic
cleansing device to stimulate blood flow and maximise penetration and there is evidence
of the active ingredients. Chemical peels in various formulations are
employed by some practitioners and there is evidence to support to support their use as a
their use as a second-line treatment in some patient groups.9,13
Common options include alpha hydroxyl acid (such as glycolic and second-line treatment in
mandelic acids) and Jessner’s peel (a medium-depth peel containing
salicylic acid, lactic acid and resorcinol). These are typically applied some patient groups
in the clinic setting, and used in combination with longer-term topical
therapies that the patient uses at home.

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Developments will likely continue to be aimed


at minimising side effects, which – paradoxically
– include increased hyperpigmentation. Dr
Ravichandran believes that advancements in
topical products like liquorice extract will lead
the way, as well as mandelic acid, which “are
showing some promise in the management of
pigmentation”. There is some emerging evidence
of the efficacy of combination salicylic and
mandelic acid peels in treating melasma and PIH,14
with more research needed.

Dr Gonzalez, however, cites more advanced and


The laser that has been at the forefront of removing skin pigment targeted lasers as the panacea in pigmentation solutions. “Lasers
for several years is the Q-switched laser, which uses selective have to be seen as the pinnacle in treating hyperpigmentation.
photothermolysis to target specific areas of hyperpigmentation. The technology has improved over the last decade or so and is
Dermatologist Dr Maria Gonzalez from the Specialist Skin Clinic improving all the time,” she remarks. The biggest development
uses the ND:Yag (neodymium-doped yttrium aluminium garnet in recent years has arguably been the picosecond laser, which
crystal) 1042 nm laser to treat darker skin, while the 532 nm laser effectively delivers a high-energy, very short-wave pulse of light
is indicated in fairer-skinned patients. She chooses laser for to a highly targeted area with minimal collateral damage to the
photo-damaged skin in patients who present with solar lentigos, surrounding skin. “I believe there is an advancement of that already
seborrheic warts and dark freckles, and to treat very extensive or waiting in the wings, so strategic and precise use of lasers is very
resistant melasma. “We focus the laser on the area of pigmentation, much the treatment of the future.”
but patients are often happier if we treat the whole face as they feel
they’ve got a more even result,” Dr Gonzalez comments. Although Greater understanding of the mechanisms that cause melasma
pre-treatment skin preparation does not significantly improve may help to channel future research into effective remedies for this
outcomes, she adds, post-treatment care will usually incorporate an condition. In general, however, a wider acceptance of the damaging
emollient-based moisturising regime. effects of the sun’s UV radiation – and importantly, adequately
protecting ourselves against the risks of damage – remains the first
Sun protection defence in staving off and dealing with this ever-challenging complaint. 
Whatever the cause of hyperpigmentation – be it UV damage,
REFERENCES
idiopathic melasma, or PIH – exposure to UV radiation generally 1. C.B. Lynde; J.N. Kraft; C.W. Lynde, ‘Topical Treatments for Melasma and Postinflammatory
Hyperpigmentation’, Skin Therapy Letter, 11(9) (2006), pp. 1-6 
exacerbates the condition. Consequently, patients should
2. World Health Organization, The known health effects of UV (www.who.int, 2015) <http://www.who.int/
take extreme care with sun exposure following treatment for uv/faq/uvhealtfac/en/index2.html>
3. Rendon M, Berneburg M, Arellano I, Picardo M., ‘Treatment of melasma’, J Am Acad Dermatol, 54
hyperpigmentation. The primary method of both optimising the
(2006), pp. 272-81
outcomes of the treatment and preventing further photo-damage 4. BMJ Best Practice, Melasma Classification (London: BMJ Best Practice, 2015) <http://bestpractice.bmj.
com/best-practice/monograph/627/basics/classification.html>
and pigmentation is use of a high sun protection factor (SPF) of
5. Pandya AG et al. ‘Reliability assessment and validation of the Melasma Area and Severity Index (MASI)
at least 30 (some practitioners recommend SPF 50+), applied and a new modified MASI scoring method’, Journal of the American Academy of Dermatology, 64(1)
(2011), pp. 78-83.
liberally throughout the year. “For anybody who embarks on
6. Richard G. Glogau, MD, & Associates, Glogau Wrinkle Scale (San Francisco: SFDerm, 2015) <http://
[hyperpigmentation] treatment, we insist on a homecare regime, www.sfderm.com/glogau-wrinkle-scale/>
7. Table adapted from ref. 6.
because without that, patients are wasting our time and their
8. Rivas S and Pandya AG, ‘Treatment of melasma with topical agents, peels and lasers: and evidence-
money,” comments Gillic. “As well as year-round SPF 50, I almost based review’, American Journal of Clinical Dermatology, 14(5) (2013), pp. 359-76.
9. Shankar K et al, ‘Evidence-based treatment for melasma: expert opinion and a review’. Dermatology
always suggest some vitamin C in the regime to help the sun
and therapy, 4(2) (2014), pp. 165-86.
protection to work that bit harder.” 10. Van Scott EJ, Yu RJ., ‘Alpha hydroxy acids: Procedures for use in clinical practice’, Cutis, 43 (1989),
pp. 222–8; Van Scott EJ, Yu RJ., ‘Hyperkeratinization, corneocyte cohesion, and alpha
Dr Ravichandran promotes sun avoidance. “It’s an absolute must
hydroxy acids’, J Am Acad Dermatol, 11 (1984), pp. 867–79; Goodman GJ, Baron JA., ‘Postacne
for all groups of pigmentation disorder,” he says. “I advise patients scarring: A qualitative global scarring grading system’, Dermatol Surg, 32 (2206), pp. 1458–66. Cited
in BS Chandrashekar et al, ‘Retinoic acid and glycolic acid combination in the treatment of acne scars’,
against sun beds and sun exposure, and recommend a high SPF
Indian Dermatology Online Journal, 6(2) (2015), pp 84–88.
that covers both UVA and UVB, along with a hat and dark glasses, 11. Schmidt JB, Donath P, Hannes J, Perl S, Neumayer R, Reiner A. ‘Tretinoin-iontophoresis in atrophic
acne scars’, Int J Dermatol, 38 (1999), pp. 149–53; Rossi AB, Leyden JJ, Pappert AS, Ramaswamy
and covering up in the sun.”
A, Nkengne A, Ramaswamy R, et al. ‘A pilot methodology study for the photographic assessment
of post-inflammatory hyperpigmentation in patients treated with tretinoin’. J Eur Acad Dermatol
Venereol. 25 (2011), pp. 398–402. Cited in BS Chandrashekar et al, ‘Retinoic acid and glycolic acid
The development of treatment and techniques
combination in the treatment of acne scars’, Indian Dermatology Online Journal, 6(2) (2015), pp.
In darker-skinned individuals, an almost-ghostly white complexion 84–88.
12. Saurat JH et al, ‘Topical retinaldehyde on human skin: biological effects and tolerance’, Journal of
with very clear demarcation lines was once a tell-tale sign of
Investigative Dermatology, 103(6) (1994), pp. 770-4.
hyperpigmentation treatment. “The only solutions years ago were 13. Rashmi S et al, ‘Chemical Peels for Melasma in Dark-skinned Patients’, Journal of cutaneous and
aesthetic surgery, 5(4) (2012): 247–253.
harsh chemicals that bleached the skin, and fully ablative laser
14. Garg VK, Sinha S, Sarkar R. ‘Glycolic acid peels versus salicylic-mandelic acid peels in active
treatment,” explains Miss Balaratnam. “Now, we have skin-lightening acne vulgaris and post-acne scarring and hyperpigmentation: A comparative study’. Dermatol
Surg. 2009;35:59–65, cited in Rashmi S et al, ‘Chemical Peels for Melasma in Dark-skinned Patients’,
agents that are so much kinder to the skin, and they’re becoming
Journal of cutaneous and aesthetic surgery, 5(4) (2012), pp. 247–253.
increasingly more sophisticated. From fully ablative to fractionally
ablative lasers, it’s interesting to see how this will develop in the
coming years.”

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Forehead
rejuvenation
and contouring
strategies
Mr Dalvi Humzah and Anna Baker discuss
anatomically-sound approaches to treating
and re-contouring the forehead
The aesthetic practitioner is able to address and successfully but little is available in the context of forehead re-contouring. In
treat many of the senescent changes of the upper face, in this article, the authors will share their specialised techniques,
particular the forehead and glabellar, through a variety of non- underpinned by regional anatomy, with discussion of approaches
surgical injectable modalities. To achieve an effective result, a described within the current literature available. The acronym
current and accurate anatomical awareness, as well as a detailed in Figure 1 (used by many medical students) will be alluded to
understanding of product suitability is imperative in order to reduce throughout the article, to allow the reader to clearly visualise the
complications and yield an excellent cosmesis. In this article, a anatomical planes described for product placement.4
variety of techniques will be analysed in terms of their suitability to
refine skin texture and re-contour this region. The Forehead
Topographically the forehead may be defined as the area bounded
Key Words laterally by the superior temporal septum which arises from the
Dermal filler, botulinum toxin A, anatomy, forehead, re-contouring temporal crest, inferiorly by the orbital rims with the supra orbital
adhesion and nasion and superiorly the hairline (a variable which is
Introduction difficult in those who are follicularly challenged).5 When describing
When considering a ‘beautiful’ face, the forehead, in terms of height, the regional anatomy, many texts will address the course and
contour and appearance, is accepted as one of the seven keystone details of individual structures, which while correct, fails to provide
areas to acknowledge.1 In this article, the anatomy of the forehead a three-dimensional description of the areas of interest for a non-
and glabellar will be reviewed with regard to the application of surgical practitioner.
specific non-surgical cosmetic treatments. It is acknowledged A different view is required when treating an area with what is
that botulinum toxin is used to effectively reduce and soften the essentially a blind approach, as the practitioner can not see the
appearance of static and dynamic rhytides at the forehead and structures under the skin whether using a needle or cannula. The
glabellar.2 The use of dermal fillers to re-contour this region can five-layered approach outlined above will enable a practitioner
provide exceptional results.3 The current literature covers varied to quickly determine the position of product placement, and
injection techniques to treat the upper face using botulinum toxin, also understand where important structures are in relation to
the approach utilised. It is, however, imperative when using this
Figure 1: SCALP approach that the practitioner has an in-depth knowledge of the
Layer one: Skin named structures in each area.
Layer two: Subcutaneous layer
Layer three: Aponeurotic layer, commonly referred to as the Layer One: Skin
SMAS layer; a strong musculo-aponeurotic sheet, encasing the A lot of vital anatomical information can be learnt by examination
whole face of this important structure. Apart from the overall appearance of
Layer four: Loose areolar tissue; a gliding plane to allow for the skin and the ageing changes, superficial arterial and venous
mimetic expression structures may be visible that will alert the injector to avoid
Layer five: Periosteum/ deep tissue (muscle/fascia) puncturing these – and, in doing so, avoid adverse events. The
dynamic lines in the glabellar region define the underlying median/

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Forehead 1 Forehead 2

MF ST

SOM SOL
LT ST
ROOF
M P

P: Procerus
M: Median forehead ST: Supratrochlear
ST: Supratrochlear vessels SOM: Supratrochlear medial
MF: Middle forehead fat pad SOL: Supratrochlear lateral
LT: Lateral temporal cheek compartment ROOF: Retro orbicularis orbital fat

central fat compartment (see layer two). The glabella line also medial forehead and the infratrochlear nerve supplies skin on the
indicates the line of the supratrochlear vessels located near the medial eyelid(s), passing above the medial palpebral ligament.10
subdermis, and the deep insertion of the medial portion of the Frontal branches of the facial nerve transition subcutaneously in the
corrugator. The lateral dermal attachments of the corrugator are temple to innervate the frontalis segmentally in the subcutaneous
often seen as a semicircular depression laterally.6 The horizontal plane (layer two).11
forehead lines represent septal dermal attachments to the Accompanying the nerves, the arteries follow a similar course.
underlying frontalis, and when running horizontally indicate the The skin of the glabellar and forehead region is mainly supplied
contiguous nature of the frontalis muscle.7 The midline dip and by branches from the bilateral supratrochlear, supraorbital and
lateral appearance of the forehead lines indicate the point of superficial temporal arteries.12 The supratrochlear artery branches
separation and lateral position of the muscle. This approach to from the ophthalmic artery in the orbit and emerges by piercing
injection, named the ‘objective-muscle-identification approach’, the orbital septum above the medial canthal tendon.10 It runs in the
will help the injector to accurately and effectively tailor toxin vicinity of the procerus and corrugator muscles in the nasal root
placement.8 and the glabellar area, passing subcutaneously in level two on its
superior path. The artery has several branches during its course and
Layer Two: Subcutaneous anastomoses with the supraorbital artery and supratrochlear artery.10
This is an important layer as many structures are located here and Within the corrugator complex, the artery is vulnerable to injury from
understanding this area in detail will allow a practitioner to reduce needle puncture from toxin needle placement and caution is advised
adverse events. Prior to the seminal work by Rohrich and Pessa, here due to its superficial path. The main artery runs in the glabellar
the subcutaneous fat was viewed as an amorphous structure under line often just under the subdermis in layer two.12
the skin. However, these authors identified three compartments.7 The supraorbital artery is the larger of the two; it divides into a
The (median) central compartment is located in the midline region superficial and deep branch, and the former penetrates the frontalis
of the forehead. It has a consistent location that abuts the middle and enters layer two; then anastomosing with the superficial
temporal compartments on either side with an inferior border at the temporal artery and lacrimal artery. It thus connects the internal and
nasal dorsum (supratrochlear artery). The lateral boundary is possibly external carotid systems.12 Due to these anastomoses within this
a septal barrier and could be referred to as the central temporal layer, the injector must approach layer two with a high degree of
septum. The middle temporal fat compartments lie on either side of caution to reduce potentially irreversible complications. The deep
the central forehead, the inferior border is the orbicularis retaining branch runs on the deep surface of the frontalis and runs obliquely
ligament, and the lateral border corresponds to the superior laterally – often leaving an indentation on the bone. Occasionally
temporal septum. The lateral temporal-cheek compartment connects the deep branch will separate in the orbital cavity and enters the
the lateral forehead fat to the lateral cheek and cervical fat. The forehead through a separate bony canal approximately one cm
separation between the middle temporal compartment and lateral above the midportion of the orbital rim.13 Deep injections of toxin
temporal compartment may occasionally be seen as an oblique in this region may spread down this canal and enter the orbital
depression on the skin in some patients. While these are important contents, resulting in ptosis.13
anatomic concepts, it is interesting to note that we are unclear as The venous return from the face is usually superficial; the
yet what their role is in the ageing of the forehead, unlike other supraorbital and supratrochlear veins traverse to the medial
regions that have been examined, for example, the mid-face fat canthus where they unite to form the angular vein.14 This becomes
compartments as described by Gierloff et al.9 the facial vein, which pursues a straight course behind the facial
Other important structures are the nerves and vessels. The artery, just below the border of the mandible. Blood from the
Trigeminal nerve (Cranial nerve V) branches supply the sensory upper lateral forehead is also collected into the tributaries of the
innervation to the forehead.5 Lateral to the medial end of the upper superficial temporal vein.14
margin of the orbit, the supraorbital nerve indents the bone into a
foramen. The nerve passes superiorly and penetrates the frontalis Layer Three: Frontalis
around the superior orbital adhesion and runs superiorly in the The occipito-frontalis is an exceptionally thin muscle, fusing with
forehead fat supratrochlear to supply the scalp and vertex. The the galea aponeurotica from the lateral two thirds of the highest
smaller supratrochlear nerve passes up on the medial side of the nuchal line of the occipital bone, extending its fine fibres anteriorly
supraorbital nerve penetrating frontalis similarly to innervate the to fuse with the procerus muscle at the nasal bone.15 It is part of

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a group of musculoaponeurotic muscles, which elevate the brow periorbital regions are the superior temporal septum, the inferior
with medial fibres blending inferiorly with the corrugator supercilli temporal septum and the supraorbital adhesion. The temporal
and orbicularis oculi muscles blending laterally with orbicularis oculi ligament arises from the frontal bone as an expansion at the
over the external frontal bone. anterior end of the superior temporal septum, inserting into the
The occiptofrontalis muscle represents the third layer in the scalp, superficial fascia at the junction of the superficial temporal fascia
which equates to the superficial musculoaponeurotic system and galea, on the deep surface of the frontalis muscle. The base
(SMAS) layer in the face. Spiegel et al established that superiorly is located parallel to the arcus marginalis of the orbital rim at a
to the nasion, the frontalis fibres are contiguous for a variable distance of 10mm above it. The superior temporal septum arises
distance before an aponeurosis is apparent in the space between from the periosteum along the superior temporal line of the
the bilateral muscles, which may vary considerably between skull and inserts into the line of junction between the superficial
individuals.16 Male subjects may display a wide variation in the temporal fascia and the galea. Anteriorly, this line of junction
medial muscle border as a ‘W’ shape with a variable attenuation occurs between the superficial temporal fascia and the galea,
point. Female subjects demonstrate a less irregular central lining the deep surface of the lateral border of the frontalis muscle;
dehiscence shape with a continuous frontalis and ‘V’ shape the expanded end is the temporal ligamentous adhesion. The
dehiscence. The dynamic forehead lines may indicate the muscle supraorbital ligamentous adhesion arises from the frontal bone
configuration (see layer one). These findings are key in analysing above the orbital rim, extending between the temporal ligament
the frontalis muscle activity accurately, to treat effectively and and the origin of the corrugator muscle. The inferior border
administer botulinum toxin judiciously. is located approximately 6mm above the deep attachment of
the periorbital septum; the ligament is condensed around the
Appropriate patient selection for botulinum toxin is crucial. Patients with branches of the supra-orbital nerve and corrugator muscle origin.
brow ptosis are poor candidates for correction of forehead ryhtides The periorbital septum originates from three-quarters of the
with toxin.1 This needs to be assessed prior to considering treatment. circumference of the orbital rim, extending from the corrugator
If present, in the authors’ experience, dermal fillers (including skin origin around to the inferomedial boney origin of the orbicularis
boosting or intradermal blanching) may provide superior results, and oculi. The origin and boundaries of these attachments are
may additionally subtly enhance the position of the brows. significant in terms of re-contouring the forehead with dermal fillers
within the supraperiosteal plane; placement with a blunt cannula
Layer Four: Loose Areolar Tissue does not permit dissection of these fixed attachments, thus,
This layer represents a gliding plane – essentially an avascular product remains safely enclosed within the desired plane and
plane. The frontalis glides over this layer and is a safe plane to anatomical boundary (Figure 1).
place dermal fillers for deep forehead contouring (see below), as
an avascular plane does not comprise any vessels or structures to Anaesthesia
compromise. For optimum patient comfort when re-contouring the forehead, it may
be preferable to block the supratrochlear and supraorbital nerves
Layer Five: Periosteum respectively. 3% mepivicaine or 2% lidocaine may utilised for this
The final layer is anatomically the point where the ligaments that purpose, with small volumes used to specifically block these nerves
define the forehead arise. Moss et al5 describe the following low in the supraorbital region.17 Lidocaine mixed with the dermal filler
arrangement of ligamentous attachments in the upper face: the may also be used, although the injection technique is slower and
temporal ligamentous adhesion supports the region immediately may still be uncomfortable for the patient.
superior to the eyebrow at the junction of its middle and lateral Topical anaesthesia is insufficient for this advanced deep technique,
thirds. Located at the intersection of the temporal, frontal and despite the use of a blunt cannula as the supraorbital nerves
innervate the underside of the frontalis and periosteum.17
Figure 2: Principle retaining ligament defining
the forehead and temporal boundary
Superior temporal Deep Correction
septum Re-contouring the forehead using a supraperiosteal
approach is gaining popularity.13 Redefining this
anatomical region provides a youthful contour,
and facilitates deep support in counteracting the
morphological age-related bone resorbtion noted in
both male and female individuals at the glabellar angle.15
Inferior temporal
septum Restoring the boney support to the frontal eminence, as
well as the lateral brow, achieves a subtle redraping of
the overlying tissues and the procedure is popular within
certain ethnic populations who strive achieve a rounded,
convex appearance to the forehead.3 Facial mapping
prior to treatment, along with baseline photography, is
key for practitioner and patient to agree on the expected
outcome from treatment.
Once the full face has been thoroughly cleaned with
chlorhexidine and hair tied back, re-contouring may be
achieved by commencing an entry point medial to the

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Conclusion
The content of this paper has been compiled to equip the clinician
A male patient may with current evidence and knowledge pertaining to non-surgical
forehead re-contouring. The key to successfully and safely treating
favour augmentation of this region is a current and accurate anatomical knowledge and in
particular an understanding of the layered concept in relation to the
the supraciliary arch to forehead (SCALP). Anatomy is a dynamic and three dimensional
subject; as anatomical awareness develops, it is imperative that
enhance a masculine practitioners keep abreast of this specialist subject. Didactic and
interactive practical teaching courses will enable an in-depth
brow in conjunction with analysis in respect to important facial structures. Once this view
is appreciated, it will enable practitioners to develop safe and
the frontal eminence, effective techniques in treating facial zones.

with threads placed Mr Dalvi Humzah is a consultant plastic reconstructive


and aesthetic surgeon, with a BSc in anatomy. He has
been a tutor for the Royal College of Surgeons of England
supraperiosteally and is an examiner for the Intercollegiate MRCS for the
Royal College of Surgeons of Glasgow. He is the lead
tutor for the award-winning teaching programme, Facial Anatomy
Teaching, and actively teaches and lectures internationally.
temporal fusion line, utilising a 25g needle entry point to the depth
of the supraperiosteal plane (layer four). Calcium hydroxylapatite Anna Baker is a dermatology and cosmetic nurse
with its highly viscous, elastic and cohesive properties without practitioner. She runs the nurse-led Medicos Rx Skin
Clinic at The Nuffield Health Hospital in Cheltenham,
additional lidocaine provides an ideal product to use in this layer.
and is the coordinator for Facial Anatomy Teaching.
A 25g cannula is inserted along the supraperiosteal plane to Baker runs nurse-led photodynamic therapy clinics for
deposit linear threads of product to augment the right and left non-melanoma skin cancer and is currently studying post-graduate
frontal eminences from the lateral entry points. The volume of Applied Clinical Anatomy at Keele University.
product required to achieve the desired result will vary between REFERENCES
individuals, depending upon the degree of correction required. A 1. Little A.C., Jones B.C., DeBruine L.M., ‘Facial attractiveness: evolutionary based research’, Trans P.,
Soc B., 366 (2011), pp. 1638-1659.
cannula length of 38mm or 50mm is preferable, depending on the 2. Dubina M., Tung R., Bolotin D., Mahoney A.M., Tayebi B., Sato M., Mulinari-Brenner F., Jones T.,
dimensions of the frontal bone; within the supraperiosteal plane, West D.P., Poon E., Nodzenski M., Alam M., ‘Treatment of forehead/glabellar rhytide complex
with combination botulinum toxin a and hylaruronic acid versus botulinum toxin A injection alone:
the cannula will glide with ease without risk of injury to nerves or a split-face, rater-blinded, randomized control trial’, Journal of Cosmetic Dermatology, 12(4) (2013),
vascular compromise. Busso and Howell describe this technique pp. 261-6.
3. Busso M., Howel J.D., ‘Forehead Recontouring Using Calcium Hydroxylapatite’, Dermatologic
as ‘horse shoe’ placement of product, which achieves a subtle Surgery, 36 (2010), pp. 1910-1913.
lift across the length of the brow. 3 A male patient may favour 4. Smith A.G., Irving’s Anatomy (4th Ed.) (Churchill Livingstone, 1972)
5. Moss J.C., Mendelson B.C., Taylor G.I. ‘Surgical Anatomy of the Ligamentous Attachments in the
augmentation of the supraciliary arch to enhance a masculine Temple and Periorbital Regions’, Plastic And Reconstructive Surgery, 105 (4) (2000), pp. 1475-1489.
brow in conjunction with the frontal eminence, with threads 6. Weider J.M., Moy L.R, ‘Understanding botulinum toxin surgical anatomy of the frown, forehead and
periocular region’, Dermatological Surgery, 24 (1998), pp. 1172-1174.
placed supraperiosteally. Following correction, the product is 7. Rohrich R.J., Pessa J.E. ‘The Fat Compartments of the Face: Anatomy and Clinical
then moulded into the desired contour, and the patient advised to Implications for Cosmetic Surgery’, Plastic And Reconstructive Surgery. 119(7):2219-2227.
8. Guerrerosantos J., Eduardo P.G.C., Arriola J.M., Manzano A.I.V.,Villarian-Munoz B., Benavides
withhold from applying makeup for 48 hours. L.G., Vazquez M.G., ‘Effectiveness of Botulinum Toxin (Type A) administered by the fixed-site dosing
Loghem et al concur that a cannula approach is preferable, approach versus the muscle area identification’, Aesthetic Plastic Surgery, 39 (2015), pp. 243-251.
9. Gierloff M., Stohring C., Buder T., Gassling V., Acil Y., Wiltfang J., ‘Aging Changes of the Midfacial Fat
and also advocate an entry point from the temporal crest.18 The Compartments: A Computed Tomographic Study’, Plastic And Reconstructive Surgery, 129(1) (2012),
ligamentous attachments in the upper face aid in retaining the pp. 263-273.
10. Sinnatamby C.S. (2006) Lasts Anatomy Regional & Applied. 11th Edition. Churchill Livingstone
product supraperiosteally, facilitated further by cannula placement.18 Elsevier.
11. Agarwal C.A., Mendenhall S.D., Foreman K.B., Owsley J.Q., ‘The Course of the Frontal Branch of the
Facial Nerve in Relation to Facial Planes: An Anatomic Study’, Plastic And Reconstructive Surgery,
Superficial Correction 125(2) (2010), pp. 532-537.
To further enhance the result of the deep correction, it is possible 12. Shimizu, Y., Imanishi N., Nakajima T., Nakajima H., Aiso A., Kishi K., ‘Venous Architecture of the
Glabellar to the Forehead Region’, Clinical Anatomy, 26(2) (2013), pp. 183-195.
to combine the use of botulinum toxin A to soften dynamic 13. Carruthers J.D.A., Fagien S., Rohrich., R.J., Weinkle S., Carruthers A. (2014). Blindness Caused by
ryhtides across the forehead and glabellar complex. For more Cosmetic Filler Injection: A Review of Cause and Therapy. Plast Reconstr Surg 134(6):1197-1201.
14. Imanishi N., Najajima H., Minabe T., Chang H., Aiso S., ‘Venous Drainage Architecture of the
established ryhtides, a cohesive, polydensified matrix hyaluronic Temporal and Parietal Regiosn: Anatomy of the Superficial Temporal Artery and Vein’, Plastic And
acid dermal filler may be combined through a ‘blanching’ Reconstructive Surgery, 109(7) (2002), pp. 2197-2203.
15. Lorenc Z.P., Smith S., Nestor M., Moradi A. ‘Understanding the functional anatomy of the frontalis
technique using a 30g needle, described by Micheels et al, who and glabellar complex for optimal aesthetic botulinum toxin type A therapy’, Aesthetic
postulate that blanching is not caused by vasoconstriction, but Plastic Surgery, 37(5) (2013), pp. 975-83.
16. Spiegel J.H., Goerig R.C., Lufler R.S., Hoagland T.M., ‘Frontalis midline dehiscence: An anatomical
instead by the transparent and transient appearance of the gel in study and discussion of clinical relevance’, Journal of Plastic, Reconstructive & Aesthetic
close proximity to the skin’s surface.19 A superficial or intradermal Surgery, 62 (2009), pp. 950-954.
17. Zide B.M., Swift R., ‘How to block and tackle the face’, Plast Reconstr Surg, 101(3) (1998), pp. 840-51.
depth may be established by ‘tenting’ the needle to visualise the 18. Loghem J., Yutskovskaya Y.A., Werschler W.P., ‘Calcium Hydroxylapatite: Over a Decade of Clinical
outline in the skin, with the bevel placed downwards, depositing Experience’, The Journal of Clinical and Aesthetic Dermatology, 8(11) (2015), pp. 38-49.
19. Micheels P., Sarazin D., Besse S., Sundaram H., Flynn T.C. ‘A Blanching Technique for Intradermal
multiple bead-like punctures, just under the skin until the rhytide Injection of the Hylauronic Acid Belotero’, Plastic And Reconstructive Surgery, 132(4S-2) (2013), pp.
has been eliminated. The product is gently massaged following 59S-68S.

correction, providing exceptional levels of correction for static


and/or superficial rhytides.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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move away from removal of excess skin and towards a trend to


replace volume and induce collagen stimulation. Restoration of the
periorbita is multifaceted and entails smoothing of the lower eyelid,
often using a combination of different modalities, such as botulinum
toxin, fillers, lasers, radiofrequency and ultrasound technology, to
achieve the best aesthetic outcome.
Increased collagen degradation and decreased collagen synthesis
means the adult skin loses approximately 1% of its dermal collagen
content on an annual basis.5,6

Treatment Options
Technological advancements have been made to increase collagen
synthesis. Skin rejuvenation can be categorised into two main
categories: invasive and non invasive. In the last decade, there
has been increased demand for noninvasive procedures for skin
rejuvenation and a simultaneous explosion of new non-surgical

Tri Eye techniques and combinations of such treatments to improve and


rejuvenate the skin around the peri-orbita. These modalities include
Intense Pulsed Light (IPL), fractionated laser treatments, radiofrequency
and ultrasound technology. The evolving list of nonablative lasers

Treatment
and light systems also includes broadband infrared light, dual yellow
laser, pulsed dye (585, 595 nm), Nd: Yag (1064, 1320nm), Diode
(910, 1450 nm) and Er: Glass (1540 nm lasers).7 IPL is a non-coherent
light that covers a large wavelength to be absorbed by the desired
chromophores. It works by causing reversible thermal damage to
collagen in the dermal layer and helps fibre remodeling without
Dr Maryam Zamani provides ablation to the epidermis.8 Regia et al showed improvement in flaccid
an overview of the aesthetic skin related to the increase of collagen in the deep reticular dermis,
promoting a skin tightening effect with IPL.8 Periorbital and facial
treatments available for rejuvenation treatment with IPL may help those patients with Fitzpatrick Skin types
of the eye, and details her ‘Tri I-IV with pigmentation and vascular issues with secondary benefits of
mild collagen induction.9
Eye Rejuventation’ and ‘Tri Eye Radiofrequency is another nonablative skin rejuvenation modality used
Transformation’ techniques to cause shrinkage of dermal collagen and promote the formation

The eyes are the aesthetic centre of the face and are often Figure 1
referred to as the ‘window to the soul’. The periorbita is an area
where we can often see the first signs of ageing and is cause for
common requests for rejuvenation in aesthetic practices. Complaints
include excess skin, fine lines and wrinkles, puffiness around the
eyes and pigmentation issues. To understand these issues we need f
to understand the process by which they occur. g

Starting in the third decade of life, redundancy of upper eyelid skin a h


begins and continues to progress until that skin rests on the upper i
b
eyelid lashes. This results in a hooded appearance that can also c
d
be accentuated by the descension of the brow and underlying fat
e j
pads. In the fourth decade of life, the lateral canthal rhytids and
accentuation of the lower eyelid folds are apparent at rest. This
is followed by the herniation of fat pads in the upper and lower
eyelids (Figure 1).1
With age, the cheek, periorbita and subobicularis fat atrophy while the Lid cheek segment
orbital retaining ligament relaxes. The process results in a downward Malar segment
Nasolabial segment
displacement of the lid-cheek junction and an indentation between
the lower eyelid and the cheek, also known as the tear trough.2
Other factors can influence the appearance of the tear trough as
well. Volume loss accentuates the nasojugal grove and the inferior a Dermatochalasis g Central fat pad
b Pelpebromalar groove h Lacrimal gland
orbital rim creating a hollow appearance (Figure 1).3 Some individuals c Malar mound i Fat herniation
are predisposed to having lower eyelid fat prolapse that can further d Mid cheek groove • Lower medial fat pad
e Tear trough • Lower central fat pad
accentuate the loss of volume directly inferior.4 Bone resorption in (Nasojugal groove) • Lower lateral fat pad
facial ageing in conjunction with soft tissue atrophy has created a f Medial fat pad j Malar fat pad (descent)

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Figure 2: Reticular vessels treated with Nd: Yag 1064 Figure 3: Tri Eye Rejuvenation: Figure 4: Tri Eye Transformation

Before Before Before

After After After

Before and two weeks following treatment Before and three months after treatment with Botulinum Before and one month following treatment
toxin A, Volbella and Ultherapy

of new collagen through controlled neocollagenesis without include reduced erythema, oedema, downtime and dyschromic
integumental injury. Radiofrequency devices are able to achieve changes, particularly important in treating Fitzpatrick skin types V
greater depths of thermal injury with tissue penetration to the level and VI.12 Such treatment modalities have an important role in treating
of the dermis and subcutaneous layer without producing thermal the delicate lower eyelid skin, particularly in patients that are not yet
burns.5 Such treatments are generally a succession of four to eight candidates for lower eyelid blepharoplasty. In a comparative split-face
treatments depending on the particular device used. trial with fractional Er:YAG and microfractional CO2 laser resurfacing
Nd: YAG 1064 laser and the Norseld Dual Yellow Laser are non- showed greater efficacy and patient satisfaction for the fractional
ablative lasers used for aesthetic rejuvenation of the face. Nd: CO2 laser,17 however recovery time and risks for CO2 laser were
YAG 1064 can be used successfully and selectively to target higher. The spectrum of adverse sequel range from mild (prolonged
haemoglobin in reticular vessels seen in the peri-orbita and erythema, milia) to moderate (transient to permanent dyspigmentation,
temples (Figure 2).10 Norseld Dual Yellow Laser also uses the 578 local infection) to severe (hypertrophic scarring, ectropian, systemic
nm yellow wavelength to target chromphores associated with infection).1
oxyhaemoglobin in red telangectatic vessels. The Norseld laser is Ultherapy is another non-invasive treatment modality using
highly successful in treating small red telangectatic vessels along microfocused ultrasound (MFU) with visualisation to create thermal
the eyelid margin.11 micro-injuries also known as thermal coagulation points (TCP) in
Fractional resurfacing for aesthetic enhancement continues to the dermis and subdermal tissue. Despite its lower energy, MFU is
evolve using ablative, non-ablative and fractional technologies capable of heating tissue to greater than 60C to a depth of 5mm
because of their improved safety profile. These three approaches within the mid to deep reticular layer of the dermis and subdermis,
mainly differ in the mode of thermal damage, degrees of efficacy while sparing the overlying papillary dermal and epidermal layers
and downtime.12 Fractional laser technology has gained increased of the skin.18,19 MFU causes collagen fibres in the superficial
popularity in improving scars, fine lines, dyspigmentation, and musculoaponeurotoic system and deep reticular dermis to contract
wrinkles because of its favourable side effect profile, recovery time and stimulate de novo collagen.18 An ultimate lift is created in the
and outcome.12,13 Common indications for both non-ablative and healing of the TVP resulting in firming, tightening and shrinking
ablative resurfacing are for periorbital wrinkles, photo ageing and of the dermis and subdermal tissues. The efficacies of Ultherapy
dyschromias. Laser resurfacing is used to help remove a specific treatments vary on the vector direction of treatment and the total
layer of skin down to a specific depth of skin. In doing so, fine energy supplied. Off label, Ultherapy has been used for improving
lines and wrinkles can be softened, pigmentation improved and the infraorbital skin laxity by both tightening the obicularis oculi
skin tightened. Ablative lasers have the advantage of predictable muscle and the orbital septum.18,20,21 Ultherapy has a reputation of
depth of tissue ablation. Erbium; YAG lasers such as the iPixel being painful; however with proper pre-treatment analgesics, this is
by Alma can represent an improvement over CO2 lasers in well controlled.22 Pain, oedema, headache, numbness, paresis, PIH,
producing less downtime.12,14,15 Fractional resurfacing produces bruising and welts are potential transient risk profiles that need to
specific microthermal zones of photothermolysis creating columns be discussed with the patient.23
of injury whereas ablative skin resurfacing creates a confluent Botulinum toxin is an effective neuromodulator used in aesthetic
area of epidermal and dermal injury.16 Fractional thermolysis rejuvenation to temporarily paralyse the muscles of facial
leaves intervening areas of normal skin untouched whereby expression thereby decreasing wrinkle lines created by muscle
re-epithelialisation and repair can occur rapidly. These treated activity. In the periorbita, botulinum toxin has FDA approval for
zones compromise 15-25% of the skin surface per treatment treatment of the crow’s feet and glabellar lines and can be effective
depending on the machine, wavelength, fluency and stacking in treating the lower eyelid lines and elevating the tail of the
application of the laser. From my experience, generally two to eyebrow. As a low risk procedure, botulinum toxin is considered a
six sessions are needed to complete a treatment. Similar to relatively safe treatment to help diminish the lines created by facial
ablative resurfacing, the thermally ablated tissue is repopulated expression.24
by fibroblast-derived neocollagenosis and epidermal stem cell Hyaluronic acid (HA) fillers are now playing an even bigger role in
production.12 The advantages of the fractionated laser treatment treating the ageing eye and face as a three dimensional approach

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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to rejuvenation with particular attention to proportional ideals. In of the appearance of the skin around the eyes but who are not yet
determining the HA to use in the periorbita it is essential to look surgical candidates or do not feel ready or willing to have surgery.
at the viscosity (how the gel flows from the needle) and elastic The ‘Tri Eye Rejuvenation’ combines botulinum toxin, HA fillers and
modulus (gel stiffness) of the product. In treating the periorbita, Ultherapy in two sessions, ten to 14 days apart, to treat brow ptosis,
I prefer using products from the Juvéderm Vycross family, crow’s feet and the tear trough in a younger patient generally aged
particularly Volbella in the anatomical tear trough because of its 30-50. In the first visit, Ultherapy is used to treat the brow and the
lower HA concentration of 15 mg/ml. A lower HA concentration lower eyelid and to promote lifting and tightening of the periorbita.
means the gel is less hydrophilic and will absorb less water from 10-14 days later patients return for treatment of the tear trough and
surrounding tissue, causing less oedema.25 HA can be injected into temples with HA fillers and toxin to the crow’s feet (Figure 3). All
the peri-orbita and malar region with both deep (pre-periosteal and patients are educated about waiting three to six months to observe
submuscular) and dermal injections in order to temporarily help the final improvement from Ultherapy and that botulinum toxin and
reduce the appearance of lines and wrinkles. While techniques HA treatments require maintenance.
vary, most incorporate serial depots of HA along the inferior orbital Alternatively ‘Tri Eye Transformation’ combines HA filler, laser and
rim, into the subobicularis oculi muscle either in a ‘haystacking’ the iPixel to treat patients that suffer more from periorbital volume
or injection-withdrawal technique to layer support. An often loss resulting in fine lines, wrinkles and prominence of vasculature.
undertreated and neglected area for HA treatment is temporal This treatment has approximately three to six days of downtime. In
hollowing and can have a significant impact on overall facial the first visit, Norseld or Nd: Yag is used to target telangectactic and
rejuvenation. All HA injections in the periorbita carry significant risk reticular vessels in the periorbita. On the same visit, iPixel is used to
and great care to understand and respect the underlying anatomy fractionally ablate the periorbital skin. Three more sessions of iPixel
must be taken to minimise potential pitfalls. are completed monthly and upon satisfaction of this resurfacing, HA
filler is injected to help augment the volume loss in the temples and
Tri Eye Rejuvenation and Transformation periorbita, which includes the tear trough and mid cheek segments.
In treating the periorbita, there is a vast array of combination
treatments that can be implemented. I find that often the most Conclusion
successful aesthetic results come from combining different Both these and other combination treatments used for rejuvenation
modalities together to create a more unified approach to of the periorbital region have been tested to show relatively
rejuvenation and improve overall patient satisfaction. Creating a long-lastingefficacy and high patient satisfaction.27, 28 Integrated
patient specific treatment plan to combat specific issues is needed treatments for the eye area using variant procedures creates a
for a complete rejuvenation. The combination of botulinum toxin greater understanding of the multifaceted changes that occur in the
type A and hyaluronic acid appear to rejuvenate the periorbital ageing face.
and temporal areas, glabella, and crow’s feet areas with minimal Dr Maryam Zamani is an oculoplastic surgeon and
adverse effects and with higher rate of patient satisfaction.26 In aesthetic doctor. Dr Zamani specialises in surgical and
my practice, I have created a triad of treatments in two specific non-surgical aesthetic procedures at the Cadogan
Clinic. A graduate from Georgetown University and
non-surgical protocols called the ‘Tri Eye Rejuvenation’ and ‘Tri
George Washington University School of Medicine,
Eye Transformation’ to address the ageing periorbita. I have a USA, Dr Zamani completed her studies at Imperial College and
significant number of patients who present in my clinic complaining Cardiff University.

REFERENCES
1. Scarborough, D., Herron, J., Khan, A., Bisaccia, E., ‘Periorbital Rejuvenation for Early Signs of Aging: 15. Alexiades-Armenakas MR, Dover JS, Arndt KA., ‘The spectrum of laser skin resurfacing:
Exploring Aesthetic Interventions Part 2’, The Dermatologist, (1) (2003) Nonablative, fractional, and ablative laser resurfacing’. J Am Acad Dermatol, 58 (2008), pp. 719-37.
2. Rebecca Tung, R., Ruiz de Luzuriaga, A., Park, K., Mauricio Sato, M., Dubina, M., Alam, M., ‘Brighter 16. Hantash BM, Bedi VP, Sudireddy V, Struck SK, Herron GS, Chan KF., ‘Laser-induced transepidermal
Eyes: Combined Upper Cheek and Tear Trough Augmentation: A Systematic Approach Utilizing elimination of dermal content by fractional photothermolysis,’ J Biomed Opt, 11 (2006).
Two Complementary Hyaluronic Acid Fillers’, Journal of drugs in Dermatology, 11 (9) (2012) 17. Lomeo G, Cassuto D, Scrimali L, Sirago P. Er: YAG versus CO2 ablative fractional resurfacing:
3. Hamman, MS., Fabi, S.,  Goldman, M., ‘Comparison of Two Techniques Using Hyaluronic Acid to A split face study. Abstract presented at American Society for Laser Medicine and Surgery
Correct the Tear Trough Deformity’, Journal of Drugs in Dermatology, 11 (12) (2012). Conference, April 2008, Kissimmee, FL.
4. S M Salvi, S Akhtar, and Z Currie, ‘Ageing changes in the eye’, Postgrad Med J., 82(971) (2006), pp. 18. Fabi SG., ‘Noninvasive skin tightening: focus on new ultrasound techniques’, Clinical, Cosmetic and
581–587. Investigational Dermatology, 8 (2015), pp. 47-52.
5. Elsaie ML., ‘Cutaneous remodelling and photorejuvenation using radiofrequency devices’, Indian J 19. Kim YS, Rhim H, Choi MJ, Lim HK, Choi D., ‘High-intensity focused ultrasound therapy: an overview
Dermatol, 54 (2009), pp. 201-5. for radiologists’, Korean J Radiol, 2008;9 (2008), pp. 291–302.
6. Chung J, Cho S, Kang S. ‘Why does the skin age? Intrinsic aging, photoaging and their 20. Suh DH, Oh YJ, Lee SJ, et al., ‘A intense-focused ultrasound tightening for the treatment of
pathophysiology’, In : Photoaging, Rigel Ds, Weiss RA, Lim HW, Dover JS, editors. (New York: Marcel infraorbital laxity’, J Cosmet Laser Ther, 14 (2012), pp. 290–295.
Dekker Inc, 2004), p. 13. 21. Pak CS, Lee YK, Jeong JH, Kim JH, Seo JD, Heo CY., ‘Safety and efficacy of Ulthera in the
7. Choi YJ, Lee JY, Ahn JY, Kim MN, Park MY., ‘The safety and efficacy of a combined diode laser and rejuvenation of aging lower eyelids: a pivotal clinical trial’, Aesthetic Plast Surg, 38(5) (2014), pp.
bipolar radiofrequency compared with combined infrared light and bipolar radiofrequency for skin 861–868.
rejuvenation’, Indian J Dermatol Venereol Leprol, 78 (2012), pp. 146-52. 22. Fabi, SG., ‘Noninvasive skin tightening: focus on new ultrasound techniques’, Clin Cosmet Investig
8. Patriota RC, Rodrigues CJ, Cucé LC., ‘Intense pulsed light in photoaging: a clinical, histopathological Dermatol, 8 (2015), pp. 47–52.
and immunohistochemical evaluation’, An. Bras. Dermatol, 86 (2011) 23. Hitchcock, T., Dobke, M., ‘Review of the safety profile for microfocused ultrasound with
9. Goldberg DJ., ‘New collagen formation after dermal remodeling with an intense pulsed light visualization’, Journal of Cosmetic Dermatology, 13 (4) (2014), pp. 329–335.
source’, J Cutan Laser Ther., 2 (2000), pp. 59–61. 24. De Boulle, K., Fagien S.,, Sommer, B., Glogau, R., ‘Treating glabellar lines with botulinum toxin type
10. Ozyurt, K., Colgecen E., Baykan, H., Ozturk, P., Ozkose, O.,‘Treatment of Superficial Cutaneous A-hemagglutinin complex: A review of the science, the clinical data, and patient satisfaction’, Clin
Vascular Lesions: Experience with the Long-Pulsed 1064 nm Nd:YAG Laser’, ScientificWorldJournal, Interv Aging, 5 (2010), pp. 101–118.
197139 (2012) 25. Eccelston D., Murphy, DK. , ‘Juvederm Volbella in the perioral area: a 12-month prospective,
11. Norseld, Laser Treatments: Vascular Lesions (norseld.com, 2014) <http://norseld.com/index.php/ multicenter, open-label study’, Clinical, Cosmetic and Investigational Dermatology (2012), pp.
laser-treatments/#tabs-2> 167-172.
12. Goel A, Krupashankar DS, Aurangabadkar S, Nischal KC, Omprakash HM, Mysore V., ‘Fractional 26. Beer KR, Julius H., Dunn M., Wilson F. , ‘Remodeling of periorbital, temporal, glabellar, and crow’s
lasers in dermatology- Current status and recommendations’, Dermatosurgery Specials 77 (3) (2011), feet areas with hyaluronic acid and botulinum toxin’, J Cosmet Dermatol, 13 (2) (2014), pp. 143-50.
pp. 369-379. 27. Kearney C, Brew D., ‘Single-session combination treatment with intense pulsed light and nonablative
13. Brightman LA, Brauer JA, Anolik R, Weiss E, Karen J, Chapas A, et al., ‘Ablative and fractional fractional photothermolysis: a split-face study’, Dermatol Surg, 38(7 Pt 1) (2012), pp. 1002-9.
ablative lasers’, Dermatol Clin, 27 (2009), pp. 479-89. 28. Choi YJ, Lee JY, Ahn JY, Kim MN, Park MY., ‘The safety and efficacy of a combined diode laser and
14. Fitzpatrick RE, Goldman MP, Satur NM, Tope WD., ‘Pulsed carbon dioxide laser resurfacing of bipolar radiofrequency compared with combined infrared light and bipolar radiofrequency for skin
photoaged facial skin’, Arch Dermatol, 132 (1996), pp. 395-40. rejuvenation’, Indian J Dermatol Venereol Leprol, 2012 78(2) (2012), pp. 146-52.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Aesthetics | July 2015 37


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Hyaluronidase
the skin tissue.7,8 This occurs when the skin region
cannot access enough blood and oxygen.8 When
injected into a vein, HA can also cause a blockage,

Protocol
resulting in blood flowing back into the tissues and
therefore increasing pressure and causing low
grade ischaemia.8
The nose is one of the most feared sites for necrosis
Aesthetic nurse Lee Rowe outlines the following HA procedures, with the tip being the
most affected.9 To give an example of how serious
protocol for administering hyaluronidase a vascular complication can be, injecting dermal
and highlights the importance of filler into the angular vessels around the nose can
understanding its use in aesthetics potentially lead to blockage and skin necrosis or,
in extremely rare cases, blindness.10 Fillers injected
into an artery in the face can travel proximally to
Introduction the internal carotid system whereby, on release of
The aesthetic community is expanding, with non-surgical treatments now pressure, the product travels into the central retinal
contributing to 75% of the market, making the industry worth an estimated artery resulting in possible visual loss or blindness.11
£3.6 billion in 2015, in the UK alone.1 Numerous training days are held across It is therefore imperative that practitioners are able
the UK, qualifying delegates to obtain and use hyaluronic acid (HA) dermal recognise the signs of an impending necrosis
fillers for their patients’ anti-ageing concerns. However, as we know, the art of and have the skills to be able to act quickly,
injecting is just one aspect of this treatment; other aspects include knowledge thus lowering the risk of harm to the patient. Not
and understanding of anatomy and physiology, consenting issues, aftercare only must a policy be in place which allows the
and, more importantly, complication management. I find practitioners are practitioner to deal with the situation, but they must
frequently raising the issue of how to treat complications on support forums, also be fully competent and confident in what to do.
networking groups and during study days. It is a worrying sight to see how many
practitioners do not feel confident nor hold the experience to deal with the When should it be used?
adverse reactions that can be so detrimental to a patient. The aim of this article is Over injection can be a potential risk when injecting
to give the reader a valuable insight into the use of hyaluronidase; how it works HA fillers, leaving the patient with unsightly lumpiness
and, crucially, when to administer it. or looking ‘pillow-faced’, with large volumes of filler
visible in the mid face.11 Nodules can also occur
What is hyaluronidase? following HA anywhere on the face, and those that
Hyaluronidases are a family of injectable enzymes that act as dispersion start within 48 hours of injection may be inflammatory
agents. These help speed up the natural breakdown of hyaluronic acid through – however, those occurring sub-acutely (up to two
hydrolysis.2 Licensed for therapeutic indications, such as increasing tissue weeks post-treatment) or late (after two weeks) are
permeability to enhance the delivery of drugs or to increase the uptake of more likely to involve infection.12 Large haematomas
subcutaneous fluids, in aesthetics, it is widely used ‘off license’.3 Off license can also be treated with hyaluronidase.6 The
does not necessarily mean it is unsafe to use, but that it is being prescribed and use of hyaluronidase can improve absorption via
administered in a way that is different to its licensed use. The license is obtained hypodermoclysis, the process of interstitial infusion or
from the Medicines and Healthcare products Regulatory Agency4 (MHRA) and will subcutaneous infusion of fluids into the body.13
state what the drug can be used for, how much to give and the age of patients It is important to stress that if the practitioner suspects
suitable to be treated with it. As long as the practitioner is acting in the patient’s infection then hyaluronidase shouldn’t be used14 and
best interests, their autonomy is respected and the patient has fully consented, antibiotics should be prescribed. However, another
then hyaluronidase can be administered in the event of an adverse reaction.5 side effect that can be resolved with hyaluronidase is
Due to this ‘off license’ use of hyaluronidase, practitioners can only seek when the Tyndall effect presents itself. This is when
guidance from other professionals (as well as use their own expertise) in order the HA is too superficially placed and creates a bluish
to judge how much hyaluronidase to use and how to reconstitute it, which can discoloration of the skin.8
be limiting if one has little experience of using it. Various factors will influence the Throughout the procedure the practitioner must
administration and dosage – for example, the concentration of HA filler, level of observe for signs of blanching of the skin, a change
cross-linking and amount of HA deposit. in appearance that may appear dusky or mottled.6 In
this instance, the patient may complain of pain and
Recognising complications with HA fillers the area might begin to feel cool to touch. If these
There are, of course, several complications associated with having a HA dermal signs are ignored then the area may turn blue and
filler treatment, such as bruising, mild swelling and tenderness at the injection tissue necrosis can occur.8 Hyaluronidase should be
site6, which can be easily managed through observation and support on the administered as soon as this complication occurs,
patient’s behalf. It is the more serious complications, such as when filler is and there is good evidence that tissue necrosis
injected into a vein or an artery, that will require medical intervention and the can be prevented or be less severe the sooner the
administration of hyaluronidase as part of its management. If HA is injected into hyaluronidase is injected.8 Hyaluronidase must be
an artery this can cause a clot formation around the filler, or the filler itself may used early, as its effectiveness in dissolving HA fillers
cause the blockage. If the vessel is significant in supplying blood to the skin, is reduced after approximately four hours.8 Whether
this can lead to necrosis, an irreversible complication that results in the death of the situation is an emergency or not, it is imperative

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

that the patient fully understands the implications of why it is being foreign hyaluronic acid filler that has been injected.15 I would
prescribed, how it will be administered and a consent form should therefore recommend treating the effect rather than absolute
be signed. Patients must also be made aware of the impending dosage, to go slow and to bring the patient back for additional
risks involved with the use of hyaluronidase and that it is being treatments. Following the use of hyaluronidase, I would suggest
used off license. observing the patient for 30 minutes in a clinical environment and
making sure they have appropriate aftercare information. Results are
How to use hyaluronidase often seen almost immediately, although I have found for denser,
more cross-linked products it may take 48 hours for the effects to
A common preparation of hyaluronidase in the UK is made be seen. A review appointment at two to three weeks should be
up of 1500 IU of hyaluronidase in a powder for Solution for booked and further treatment offered at this point if needed.
Injection / Infusion.14 This comes as a freeze-dried white
powder in small glass vials or ampoules. As a prescription only Conclusion
medication (POM), it should only be administered following a Hyaluronidase plays an important role in the management of treating
face-to-face consultation with the prescriber. complications with HA dermal fillers, however, it should not be a
substitute for good technique. Practitioners who deem themselves
Below is my technique for preparing hyaluronidase 1500IU: qualified to inject and treat patients with HA fillers must also be
capable and confident to treat and manage complications. Having
1. Draw up 10ml of water for injection or 0.9% normal saline in some knowledge into the use hyaluronidase is not enough to keep
a syringe. and patients safe, and so it is imperative that a policy is in place that
2. Reconstitute the hyaluronidase 1500IU with 1ml of the 10ml of all injectors can follow, justify and administer hyaluronidase without
normal saline or water for injection. delay in an emergency situation. The policy must provide a set of
3. Rotate the vial to ensure the powder is fully dissolved. guiding principles to help with decision-making. This doesn’t have
4. Draw up the 1ml of hyaluronidase back into the syringe with to be complicated but understood by all injectors and reviewed
the remaining 9ml saline or water for injection thus giving a regularly. The need for patch testing doesn’t appear mandatory yet
concentration of 150IU/ml. Each 0.01ml will then be 1.5IU of but is often recommended, especially if the situation is not urgent.
hyaluronidase.
Lee Rowe is an independent nurse prescriber and
aesthetic nurse with more than five years of aesthetic
Once the solution is prepared, using a clean non-touch experience. Lee set up Innersense Aesthetics with her
procedure, inject the hyaluronidase into the affected area friend and fellow nurse Lorraine O’brien, after leaving
in small aliquots using a 30 gauge needle for superficial the NHS some years ago, and now works full time in
aesthetics in her clinic in York.
injections and 27 gauge for deeper deposits.
Administration should be extremely accurate and limited REFERENCES
1. Dr Maurizio Cavallini, Dr Riccardo Gazzola, Dr Marco Metalla, and Dr Luca Vaienti, ‘The Role of
to the affected area. In the case of nodules, they should Hyaluronidase in the Treatment of Complications From Hyaluronic Acid Dermal Fillers’, Aesthetic
be injected directly, and for product that has been injected Surgery Journal 33(8) (2013), 1167–1174
2. Hyaluronidase, (US: Drugs.com, 2015) <http://www.drugs.com/cdi/hyaluronidase.html>
into the superficial dermis, injections should be placed 3. Hyaluronidase Enzyme (UK: Clinica London, 2013) <http://www.clinicalondon.co.uk/hyaluronidase-
immediately into and below the product.10 For vascular enzyme/>
4. Medicines and Healthcare Products Regulatory Agency, (UK: Gov.uk, 2015) <https://www.gov.uk/
compromise, serial puncture should be used to inject government/organisations/medicines-and-healthcare-products-regulatory-agency>
hyaluronidase along the course of the vessel. The needle 5. Off-label or unlicensed use of medicines: prescribers’ responsibilities, (UK: Gov.uk, 2009)
<https://www.gov.uk/drug-safety-update/off-label-or-unlicensed-use-of-medicines-prescribers-
should be perpendicular to the skin and several injections are responsibilities>
often necessary. During and after the procedure, I recommend 6. P Lafaille, A Benedotto, ‘Fillers: Contraindications, Side Effects and Precautions’, Journal of Cutan
Aesthetic Surgery 3(1) (2010), 16-19.
massaging the treated area quite vigorously to optimise the 7. Necrosis, (US: National Library of Medicine, 2013) <http://www.nlm.nih.gov/medlineplus/ency/
result and aid mechanical breakdown. article/002266.htm>
8. Inglefield C, Collins F, Duckett M, Goldie K, Huss G, Paun S, Williams S, Expert consensus of
Botulinum Toxin and Dermal Filler Treatment second edition (UK: Aesthetic Medical Expert Group,
2014)
9. Dr Lisa Danielle Grunebaum, Dr Inja Bogdan Allemann, Dr Steven Dayan, Dr Stephen Mandy and
What are the risks of administrating hyaluronidase? Dr Lesley Baumann, The Risk of Alar Necrosis Associated with Dermal Filler Injection, (US: Denova
One complication following the administration of hyaluronidase Research, 2009) <http://www.denovaresearch.com/sites/default/files/2009-%20The%20risk%20
of%20alar%20necrosis%20assocaited%20with%20dermal%20filler%20injections.pdf>
is allergic reactions,11 and, according to clinical studies, occur at a 10. Berthold Rzany, Petra Becker-Wegerich, Frank Bachmann, Ricardo Erdmann and Uwe Wollina,
frequency of approximately 0.05% to 0.69%.1 There appears to be ‘Hyaluronidase in the correction of hyaluronic acid-based fillers: a review and a recommendation for
use’, Journal of Cosmetic Dermatology, 8 (2009), 317–32
conflicting evidence as to whether a patch test of hyaluronidase 11. David Funt and Tatjana Pavicic, ‘Dermal fillers in aesthetics: an overview of adverse events and
should be carried out to rule out evidence of allergic reaction, with treatment approaches’, Journal of Clinical, Cosmetic and investigational Dermatology, 6 (2013),
295-316
several practitioners suggesting that when it is used for elective 12. Jessica A. Savas, Steven Yang, Katlein Franca, Ivan Camacho, Keyvan Nouri, ‘Inflammatory Nodules
treatments a patch test should be carried to minimise the risk.8 Following Soft Tissue Filler Use: A Review of Causative Agents Pathology and Treatment Options’,
American Journal of Clinical Dermatology, 14(5) (2013), 401-411.
The patch test should be done intradermally (within or between 13. Dr Menahem Sasson and Dr Pesach Shvartzman, Hypodermoclysis: An Alternative Infusion
the skin) and I would advise the practitioner to look for signs of Technique, (US: American Academy of Family Physicians, 2001) <http://www.aafp.org/afp/2001/1101/
p1575.html>
inflammation, erythma and persistent itching. However, if the 14. Package Leaflet: Information for the User, (UK: MHRA.gov.uk, 2014) <http://www.mhra.gov.uk/home/
patient is showing signs of a vascular compromise then it could be groups/spcpil/documents/spcpil/con1424670915822.pdf>
15. Claudio DeLorenzi, ‘Complications of Injectable Fillers, Part I’, Aesthetic Surgery Journal, 33(2013),
justifiable to use the hyaluronidase as soon as possible to lower 561.
the risk of further harm.
Another possible side effect of hyaluronidase is its potential to
degrade the body’s natural hyaluronic acid in preference to the

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Treating acne
scarring with fillers
Dr Renée Hoenderkamp discusses the treatment
of acne scarring with dermal fillers
Introduction Pros and cons
Acne scarring can be distressing and stigmatising, especially when affecting Procedurally, the biggest consultation discussion
the face. Whilst there are a multitude of treatment options available, I do see point is permanence. Using semi-permanent fillers
patients who have tried everything including combinations of lasers, peels, means improvement will gradually wear off and need
retinoids and needling, but are still searching for a solution. I therefore decided repeating. My experience is that scars rarely return
to try and treat some atrophic scars with hyaluronic acid (HA) fillers and to their previous state due to a degree of subscision
witnessed some excellent results. When treating acne scarring with fillers, I use that occurs (and can be actively carried out) during
one of two techniques depending on the scar type and number. Injecting filler administration. Filler type will dictate longevity, but I
carefully into the dermis/epidermis underneath atrophic scars lifts them and use HA fillers, so six to 12 months is the norm.3 Results
improves the overall look of skin blighted by acne scarring. This can be done are instant and improve over the following weeks. I
by either individually targeting pitted scars with a plumping filler or approaching often address specific scars for patients preparing for
an entire area with a lighter filler, used mainly as a skin booster for hydration a big event, so timing is key and having the treatment
and skin conditioning. Having said this, all filler types are being used to treat a few weeks before the event, and not a few days,
acne scarring.1 is always advisable. The procedure is painful but
bearable. Some practitioners use lidocaine cream,
Anatomy of acne scarring but I find the associated local oedema is detrimental
Acne scars occur when pustules go on to form nodules and cysts. Scarring to scar visualisation, so I avoid using anaesthesia.
is the result of skin damage during the healing of active acne. This process Anecdotally, it appears to be less painful than lip
produces two typical scar types; atrophic and hypertrophic scars, depending fillers and these patients have often had many painful
on whether there is a net gain or loss of collagen in the healing process.2 A net procedures to treat the indication previously, so may
loss forms an atrophic scar (80-90%) and a net gain a hypertrophic or keloid be more tolerant than other filler patients. Injection
scar (10-20%).2 Both processes arise from the same pathophysiology, involving site redness and bruising is a possibility, as with all
a transition through three stages of damage and healing. The damage caused filler procedures, so careful consenting is key to
initially by inflammation of a blocked sebaceous gland causes blanching and managing expectations and guiding patients on how
vasoconstriction. The immune response floods the area with granulocytes, long potential side effects may last.
macrophages, neutrophils, lymphocytes, fibroblasts, and platelets, preparing
for granulation via immune mediator release. As granulation progresses the Is it effective?
final stage is seen: matrix remodelling. The area is then flooded with enzymes, Certainly my experience suggests the use of fillers
released from fibroblasts and keratinocytes, which determine the final structure is an effective solution for atrophic scar reduction.
of the extracellular matrix (ECM). Any imbalance in the enzymatic breakdown Results are seen instantly and improve over weeks
and rebuild of tissue results in scarring.2 When using fillers to treat acne scarring, as there is a double effect from the procedure:
only atrophic scars can be treated, because they are the only scars which are physical lifting up and out of the scar, and collagen
depressed, and these are generally classified into three types; boxcar, ice-pick development that often follows from fibroblast
and rolling (Figure 1): stimulation in the dermis by the needle. Not all scars
respond equally, and response is governed by type
and depth of scar and how disrupted the underlying
tissue is; this dictates filler placement and can’t be
predicted. I have found broad rolling scars that are
distensible when the skin is stretched respond best to
fillers, but I have also had success with box car and ice
pick scars that are not too narrow. The improvement,
whilst varied, is always in my experience evident, and,
however slight, is of psychological benefit. These
patients have often struggled for years to improve
their scars, and resulting expectations are lower than
the usual filler patient. They are often so appreciative
of small improvements that it is humbling and a useful
reminder of the stigma suffered.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

What filler? Technique


Essentially, any proven safe and efficacious dermal filler could potentially The procedure is relatively straightforward, but
be used and selection is governed by the experience and expertise of the it takes longer than other filler procedures. It is
practitioner. There are more than 120 fillers on the market in the UK but HAs are intricate and the local oedema is substantial, so
the most commonly used.4 I prefer them for acne scars and, whilst I turn to both being methodical about how to inject the area is
Galderma and Allergan, I tend mainly to use Emervel Classic for direct lifting crucial.
out of scars, and Restylane Vital/Vital Light for an all over skin improvement
Lifting out individual scars:
approach. This is because Emervel is firm enough to lift out deep scars but
1. Clean the area and photograph well. The
malleable enough to mould if necessary. Restylane Skin Boosters provide an
photographs are an important record and
excellent extra string to the bow when looking at skin in poor condition with
procedure tool. I use an iPad to display them
additional acne scarring, rehydrating rather than volumising to improve overall
and discuss the scars with the patient, identifying
skin texture. As these are resorbable fillers, the effects are not permanent,
areas/scars causing most distress. Only after this
although longevity varies. Whilst there are permanent fillers on the market,
discussion do I start.
it would be inadvisable to use them on acne scarring where the option to
2. Begin at the very furthest edge of the treatment
reverse any unwanted side effects is not available. As well as HA, potential
area and work methodically into the area scar
compatible filler types include poly-l-lactic acids (Sculptra), bovine collagen
by scar.
gel, polymethylmethacrylate (Bellafill) and calcium hydroxylapatite (Radiesse).1
3. Insert the needle, bevel up under the scar and,
Interestingly, Bellafill is the first filler with FDA approval and is licensed for acne
when directly under the pitted/dipped area,
scar treatment in the US.5
begin injecting. You should see immediate lifting
Poly-l-lactic acids (Sculptra): Designed to stimulate collagen synthesis over
out of the area. Withdraw and examine. You
and above that achieved by needle entry, which could give a long-term result
may need to repeat several times until you have
if substantial. Can last several years. Requires a series of injection applications
achieved the desired effect.
over a few months to get results and results are not reversible.1
4. Refer to photography as necessary; some
Bovine collagen gel: An older solution and not so readily used at clinic level
scars will become visible only at certain angles.
any longer. Bovine in origin rules it out on diet and religious grounds for some
If there is a scar on the photograph that you
patients. Results for depressed rolling scars can be good but only last two to
can’t see on the patient, change your angle or
four months. Too soft for any fibrotic scars.6,7
reposition the patient.
Polymethylmethacrylate (Bellafill): The only filler to have a licence for acne
5. Some scars have such tortuous tissue sitting
scar treatment in the US, although only for shallow distensible (rolling) scars.
under them that when the needle is extruded
Not yet readily available in the UK.5
the filler moves to the side. If this happens,
Calcium hydroxylapatite (Radiesse): A cellulose like water-based gel that
withdraw and massage the filler ensuring that
contains calcium hydroxyapatite in microscopic particles designed to create
it is not noticeable. Then, use the needle to
volume. Not as malleable as HAs but can last up to a year.1
subcise the scar tissue by moving the needle
back and forth in different directions. When you
Treatment feel that you have broken down some of the
The ideal patient for demonstrating this technique would have scattered deep scar tissue, attempt to re-site the filler.
scars. Figures 2, 3, 4 and 5 show one of the first patients that I treated for acne 6. Continue across the area, massaging the
scarring using dermal fillers. Here I used Juvéderm Ultra to treat the deepest scars filler under each scar as necessary. Working
seen. The after photos (Figure 3 and 5), taken immediately post procedure, show methodically across the area is crucial because
marked initial improvement which will develop with time. When the needle marks local oedema will grow and individual scars
and oedema subside the results are often remarkable. Although Juvéderm Ultra is will become difficult to isolate. You will reach a
an excellent choice for many filler procedures, I now tend to use Emervel Classic point where local oedema/entry points make
due to it being more malleable and versatile. any further procedure impossible. Recognise
this point and stop. It may mean that when the
Complications oedema has settled there is more that you
Complication risks are as for any fillers and the patient must be consented in can achieve, but results will already be evident
exactly the same way. Risks specific to this treatment appear to be nodules/ and my experience is that a happy patient is
prepared to undertake future treatments.
For using skin boosters, this is my approach:
1. Prepare as above.
2. Use the normal multi-injection point technique
and shallow placement as for standard skin
booster treatment.
3. At individual scars, concentrate several product
placements directly under the scar as you would
when using a standard HA for lifting a scar.
4. Massage the entire area afterwards, checking
the individual scars are not raised.
Fig 2: Left cheek before HA filler Fig 3: Left cheek after HA filler

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

lumps/visible filler caused by too superficial a placement. Avoid offer a good solution for many patients but it is important to be
this by careful examination and massaging the area post- realistic; select your patient carefully and guide them as to the
treatment. I always give the patient careful instructions for when improvement that may be achieved.
their oedema has settled. I tell them not to worry about filler that Show them which scars you believe will benefit from treatment
they can feel, only that which they can see and don’t like. and those which may not, and make sure they are happy with the
I show them how to massage any such areas, but tell them that in proposed improvement before starting by conducting a thorough
an ideal world I will have done a good enough job that they won’t consultation. Take good, clear photos and always warn the patient
need to touch it. I always add to the consent that when treating about how they will look at the end of the treatment. As with all
very shallow scars a balance has to be found between placing the cosmetic procedures, managing expectation is key to happy
filler superficially enough to lift the scar but deep enough not to be patients.
seen. Ultimately, any stubborn superficial filler could be dissolved
Dr Renée Hoenderkamp is a GP registrar based in
with hyaluronidase, but thus far I have not had to do this. You London, having qualified in April 2010. With a special
should always warn the patient that they will probably look worse interest in aesthetics and women’s health, she founded The
on finishing, but explain that this is temporary. The procedure Non Surgical Clinic in 2011, developing a reputation for
involves so many needle-points that the combination of this with natural-looking solutions for facial ageing and deformity.
oedema and potential bruising can be visually displeasing. REFERENCES
1. Treatment Options: Fillers (Canada: A Scar Free Me, 2014) <www.ascarfreeme.com/resources/>
2. Gabriella Fabbrocini, M C Annunziata, V D’Arco, V De Vita, G Lodi, M C Mauriello, F Pastore, G
Conclusion Monfrecola. ‘Acne Scars: Pathogenesis, Classification and Treatment’, Dermatology and Practice,
Acne scarring is a debilitating and stigmatising condition, which October (2010)
3. Michael H Gold, ‘Use of Hyaluronic acid fillers for the treatment of the aging face’, Journal of
drives patients to seek out and spend vast amounts of money in Clinical Interventions in Aging, 2(3) (2007), 396-376.
their quest to improve the situation. By the time they reach the 4. Dermal Fillers (UK: Doctors Makeover, 2015) <http://www.cosmeticsurgeryuk.com/dermal-fillers.php>
5. What is Bellafill? (US: Suneva Medical Inc, 2015) <www.bellafill.com/physician/acne-scar>
point of fillers, they have already tried almost all other modes 6.  Varnavides CK, Forster RA, Cunliffe WJ, ‘The role of bovine collagen in the treatment of acne
of treatment and have spent thousands of pounds. This is both scars’, British Journal of Dermatology, 116(2) (1987), 199-206.
7. Lisa Sefcik, Collagen Treatment for Acne Scars (US: Live Strong Foundation, 2015) <www.
good and bad. It is positive because they will appreciate small livestrong.com/article/74155-collagen-treatment-acne-scars/>
improvements, but could be negative because they can be
vulnerable and sometimes have unrealistic expectations. Fillers

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Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Liposuction
Dr Amanda Wong-Powell discusses
the evolution of liposuction and
presents the case study of a patient
who underwent VASER Liposuction
in her clinic
Background
Liposuction has long been a common procedure in the aesthetic
industry. As early as the 1920s, a French surgeon called Charles
Dujarrier first attempted liposuction by sculpting a ballet dancer’s
calves and knee. Due to an arterial injury, however, the leg was
subsequently amputated, which put a halt on the development of
liposuction for more than 50 years.1,2 It was not until the late 1970s
that Arpad Fischer, Giorgio Fischer, Yves-Gerard Ilouz and Pierre procedures to be performed with a reduced risk of blood loss.5
Fournier developed modern liposuction techniques in France Since then, there has clearly been an increase in the uptake of
and Italy. By the 1980s, the techniques had become popular liposuction procedures, something that has continued into the
in the United States, and, in 1985, Jeffrey Klein revolutionised 21st century. Today, there are many different types of liposuction
liposuction by perfecting the tumescent technique.1,2 Prior to available, including suction-assisted liposuction (SAL), power-
this, all liposuction procedures were performed under general assisted liposuction (PAL), ultrasound-assisted liposuction (UAL),
anaesthetic. This meant that they were associated with significant twin cannula-assisted liposuction (TCAL), external ultrasound-
surgical blood loss and a longer recovery time.3 The tumescent assisted liposuction (EUAL), water-assisted liposuction (WAL),
technique, however, permitted liposuction to be performed and laser-assisted liposuction (LAL).6,7 In my practice, however,
under local anaesthetic, which significantly reduced the level I tend to specialise in Vibration Amplification of Sound Energy
of blood loss, haematoma, recovery time and discomfort post at Resonance (VASER) Liposuction. I find the VASER technology
procedure.3,4 The tumescent, meaning ‘swollen’, technique helps to preserve the connective tissues in the body, which
involves the use of a tumescent solution. The solution comprises ultimately lowers down time for patients as it is a less invasive
a low concentration of lidocaine and adrenaline, which causes the treatment. It also maintains fat cells’ viability for fat grafting
targeted tissue to become swollen and firm, permitting liposuction purposes and, in my opinion, gives very precise body contouring
results to enable better high definition sculpting.

The tumescent technique VASER Liposuction


VASER Liposuction is fast becoming one of the most popular
permitted liposuction variants of liposuction,6 and was invented by Dr William W Cimino
when he first began developing VASER systems in 1998.
to be performed under The procedure involves three major steps: 7,8,9
• Firstly, infiltration with tumescent fluid is carried out by injection
local anaesthetic which into the fatty tissue layer.
• The fat tissues are then emulsified by ultrasound energy
significantly reduced delivered by a small multi-ringed probe. The high frequency
vibrations of the system cause gas bubbles within the tumescent
the level of blood loss, fluid to expand and collapse, thus dislodging the fat cells and
mixing them into the infiltration fluid. This is known as ‘acoustic
haematoma, recovery time streaming’.
• Finally the fluid and emulsified fat is subsequently removed by
and discomfort post the suction cannula.
VASER Liposuction is also gaining popularity with patients
procedure as it is the only recognised technology for mid-definition and
high-definition body sculpting techniques, which aim to deliver
muscular definition and a finer athletic finish to patients.10

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Case study
Patient A is a 28-year-old female postgraduate student who had patient and the accessibility of the area to be treated. Once the
gained approximately 10kg within the last couple of years whilst local anaesthetic started working, a small incision of approximately
studying for her master’s degree. She was stress eating, had no 0.8mm was made.
time for exercise and had adopted some unhealthy lifestyle habits.
Prior to seeing me, she had started an exercise regime, started to Tumescent solution is injected into the fatty tissues to achieve
eat regularly and had followed a good diet plan – as a result she infiltration. The formula used in the tumescent was; in each litre of
had lost approximately 3kg. She found that there were certain areas normal saline (0.9%), to add:
where the fat was proving rather more difficult to shift. At that point - 1mg of Adrenaline
she decided to seek help and after some research was interested - 12.5ml Sodium Bicarbonate
in having VASER Liposuction. Her first consultation was a general - 800mg Lidocaine 2% (a total maximum average of 35-45mg/kg
chat about the procedure, her suitability, her motivation, and her of Lidocaine in the tumescent fluid)
expectations from the procedure. A thorough medical history was
also taken and an examination performed. We also discussed The tumescent fluid acts as a local anaesthetic as well as a buffer
the benefits and risks of the treatment. She was then sent home for liposuction. After approximately 20 minutes, the VASER probe
to consider her options and decide whether she wanted to have was introduced and the fat emulsification process started. For each
a further consultation, if she was still keen to go ahead. She was 100ml of infiltration, VASER is applied for a maximum of one minute.
seen two weeks later; when we went through the consent process, The ultrasound energy causes the bubbles of the infiltration fluid to
the risks and the benefits again. We then looked at the areas of expand and collapse, thus dislodging the fat cells from the tissue
concern and worked out what was possible to achieve with her matrix. The ‘acoustic streaming’ then further separates the fatty
procedure. It was decided that she would have liposuction to her tissue into small packets of fat cells that subsequently mix into the
upper and lower abdomen as well as her flanks. We discussed the infiltration fluid ready for suction. The suction was performed using
pre-operative plan, logistics, the procedure itself and post-operative a specialised VentX cannula, which helps to remove the emulsified
advice. We also discussed how she was going to maintain her new fluids and fat while preserving the tissue matrix. With Patient A,
body shape. specific suction techniques were used to give her better definition
She was started on prophylactic oral antibiotics two days prior of her abdomen and to enhance some musculature and lines. A
to her procedure. In my practice, routine prophylactic antibiotics total of 2.5 litres was aspirated, of which 1.5 litres was pure fat. A
(co-amoxiclav) are prescribed to prevent infection. The liposuction suitable surgical compression garment was applied immediately
procedure was performed under local anaesthetic. On the post operation. Patient A was able to get up immediately and
morning of the procedure, she was re-consented routinely for her walked to the recovery room. After a short recovery period and
procedure. I answered all of her final questions and queries and further observations, take-home medications were prepared
then marked her body for the areas where I would perform the comprising further antibiotics and analgesia, and Patient A’s relative
VASER Liposuction. Important structures such as the xiphisternum, escorted her home.
rib cage, other important landmarks and incision areas for portholes She had MLD massages on the third day post procedure and
are marked whilst the patient is standing upright. Patient marking underwent a total of 10 sessions in the following two weeks.
is similar to drawing a topographic map with the contour lines She wore her compression garment consistently for four weeks,
representing the elevation on the surface and, in this case, the fat day and night. I saw Patient A for a routine follow-up at two weeks,
tissues. Frontal, bilateral and back view photographs were taken six weeks and twelve weeks. Patient A’s recovery was uneventful.
to help with photographic documentation and for before and after She was very pleased with her results and she continued with
comparison. It is also important to point out any asymmetry or her exercise, healthy diet and lifestyle to maintain her new body
scarring the patient may have prior to surgery, as well as checking shape. Patient A is a good case example of a very compliant, highly
for any hernias. Routine observations are taken prior to starting motivated and suitable patient with good results. As such, this case
and every 15 minutes during the procedure if the patient remains particularly highlights the importance of patient selection.
stable. As we are infiltrating Before Eight weeks after VASER Liposuction
a significant amount of fluid
into the patient, it is important
to ensure that the patient
empties their bladder prior
to starting. Standard sterile
preparation and draping is
used. Local anaesthetic is
then injected into the marked
porthole areas. In this case,
we used five portholes, which
is average for this procedure,
although sometimes we may
use more or less portholes
depending on the size of the

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

Patient selection, safety and post-operative care swelling and lymph drainage. It is a very efficacious massage
Patient selection is key in most procedures in aesthetic practice. that helps to improve the lymphatic system as well as stimulating
In procedures such as liposuction this holds particularly true and increasing the rate of removal of waste products, toxins and
in order to ensure good and sustainable results. Patients with excess fluid from the body’s tissues.11,12
unrealistic expectations, who are extremely overweight, have A short period of rest (typically 12 hours) is recommended directly
poor skin laxity, poor compliance, or multiple medical problems after the procedure, followed by two to three weeks of general
would not be suitable candidates. If patients have unrealistic recovery when strenuous activities should be avoided. Simple
expectations, it is likely that they will not be entirely satisfied with analgesia post procedure will help keep patients comfortable and
the results of the procedure, while overweight patients who are relieve their initial pain in the first few days. Patients should be able
not compliant with the aftercare may need other interventions to return to sedentary work in about a week and more strenuous
such as bariatric surgery to achieve long-term successful work within two to three weeks. Light exercises are encouraged two
results. In addition, patients suffering from skin laxity may need weeks after the procedure and more strenuous ones around four to
an abdominoplasty following liposuction treatment to remove six weeks after the procedure are often recommended. It is essential
any excess skin. As for any surgical procedure, taking a good that patients are able to commit themselves to a healthy lifestyle,
medical history and performing a thorough examination is of vital comprising a balanced diet and a post-operative exercise regime to
importance. Explaining the procedure in basic layman terms to achieve the best possible result and maintain their new body shape.
the patient, and discussing the associated benefits and risks, are
equally important. Risks discussed should include asymmetry, Conclusion
bleeding, bruising, haematoma, swelling, pain, chronic pain, VASER Liposuction is now often coupled with fat grafting.16 In
infection, neurovascular damage, lipodystrophy, unevenness, my opinion, this technique will be the new frontier of aesthetic
change in skin and skin sensation, skin burn, skin laxity, medicine and surgery, along with the practise of harvesting
Lidocaine toxicity, seroma and scarring. Other rare risks include stem cells and the use of platelet rich plasma (PRP). These can
perforation, surgical shock, organ damage and death.11,12,13,14,15 be mixed with the harvested fat to enhance the viability and
Managing the patient’s expectations is paramount. It is important longevity of the fat graft, as well as to improve skin rejuvenation.
to ensure that the patient is aware of the entire process of the The harvested autologous fat can be re-injected into the breasts,
liposuction procedure from pre-operative preparation through buttocks, face, décolletage, hands and wherever necessary for
to peri-operative and post-operative management. It is crucial volumising and revivifying purposes.17 Liposuction is the second
that patients are made aware that results are often only visible most popular aesthetic procedure performed in the world today.6
six weeks post procedure, and best results around 12 weeks Given careful patient selection and appropriate procedure
post procedure, to ensure they are not initially disappointed design, diligent pre- and post-operative care, along with effective
with the outcome. Patients also need to understand the risk operative techniques, I have found VASER Liposuction to offer
of bruising, swelling, pain and ‘leakage’ post procedure. They highly satisfactory outcomes to a range of patients.
need to be compliant with the post-operative care requirement
Dr Amanda Wong-Powell is the founder and medical
of wearing a surgical compression garment for approximately director of Dr. W on Harley Street. She has completed
two to four weeks, as well as having manual lymphatic drainage her basic surgical training, and is a member of the
(MLD) massage for the first couple of weeks.12 The surgical Royal College of Surgeons (Edinburgh). She is a VASER
compression garment helps the skin contract smoothly to the liposuction surgeon, and also has an interest in weight
loss management. She is also medical director of Meducatus, the
body’s new contours. The MLD massage is aimed at decreasing medical training platform for doctors and surgeons.

REFERENCES
1. Flynn TC, ‘History of Liposuction’, Dermatologic Surgery, 26(6) (2000), pp.515-520.
2. Coleman III, William. P. ‘The History of Liposculpture’, Journal of Dermatologic Surgery &
Oncology, 16 (12) (1990), p.1086.
3. KleinLipo, Dr Jeffrey Klein M.D (US: KleinLipo, 2013) <http://kleinlipo.com/staff/dr-jeffrey-klein/>

Patients with unrealistic 4. Klein JA, ‘Post-tumescent liposuction care: Open drainage and bimodal compression’, Derma-
tol Clin, 17 (1999) pp.881–90.
5. Rudolph H, De Jong M, ‘Tumescent Anesthesia: lidocaine Dosing Dichotomy’, International

expectations, who are Journal of Cosmetic Surgery and Aesthetic Dermatology’, 4 (1) (2004), p.1. <http://online.liebert-
pub.com/doi/abs/10.1089/153082002320007412>
6. Liposuction 2nd most popular aesthetic surgery procedure in the world (ISAPS, 2013) <http://

extremely overweight, www.isaps.org/Media/Default/Current News/ISAPS 2013 Statistic Release FINAL (2).pdf>


7. Shiffman MA, Di Giuseppe A, ‘Liposuction Principles and Practice’, Springer (2006).
8. Shiffman MA, Di Giuseppe A, ‘Body Contouring’, Springer (2010).

have poor skin laxity, poor 9. VASERlipo Science (VASER from Solta Medical, a division of Valeant Pharmaceuticals North
America, LLC) <http://www.vaser.com/vaserphysician/vaser-science/vaserlipo-science>
10. Hoyos EH, Prendegast PM, ‘High Definition Body Sculpting’, Springer (2014).

compliance, or multiple 11. Housman TS, Lawrence N, Mellen BG, George MN, Filippo JS, Cerveny KA, et al, ‘The safety of
liposuction: Results of a national survey’, Dermatol Surg, 28 (2002), pp.971-8.
12. Coleman WP, 3rd, Glogau RG, Klein JA, Moy RL, Narins RS, Chuang TY, et al., ‘Guidelines of

medical problems would care for liposuction’, J Am Acad Dermatol, 45 (2001), pp.438-47.
13. Lawrence N, Coleman WP, ‘Liposuction’, J Am Acad Dermatol, 47 (2002) pp.105-8.
14. Coleman WP, ‘Powered liposuction’, Dermatol Surg, 26 (2000) pp.315-8.

not be suitable candidates 15. Venkataram J, ‘Tumescent Liposuction: A Review’, J Cutan Aesthet Surg, 1(2) (2008) pp.49-57.
16. Schafer ME, et al., ‘Acute Adipocyte Viability After Third-Generation Ultrasound-Assisted Lipo-
suction’, Aesthetic Surgery Journal, 33(5) (2013) pp.698-704.
17. Fisher C, et al., ‘Comparison of Harvest and Processing Techniques for Fat Grafting and Adipose
Stem Cell Isolation’, Plastic Reconstructive Surgery, 132(2) (2013) pp.351-61.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

in the superficial dermis.2 It is also claimed that the injection of


mesotherapy products promote skin rejuvenation by increasing both
hydration and fibroblast activation, and re-establishing skin tone
and elasticity.3 At present, mesotherapy is used to treat a variety of
conditions such as acne, rosacea, cellulite, localised adipocytes,
stretch marks and hair loss, as well as for skin rejuvenation. In this
article I will highlight the case study of a patient with dry skin below the
eyes and the mid cheek area.

Treatment Protocol
The mesotherapy for hydration protocol consists of four sessions.
These four sessions are carried out weekly or fortnightly depending
on the availability of the patient. To ensure efficacy and even delivery

Mesotherapy
of product to the skin, the treatment is performed with an automated
mesogun, ensuring that each individual injection perforates the skin at
the same depth and with the same amount of product.

for Facial Skin Session 1


Each session utilises the same protocol of products – in my practice
I use a cocktail of products to improve different aspects of the skin.

Hydration For skin hydration I use the following products and ingredients shown
in Table 1. This protocol can be individually tailored depending on
the requirement of the patient and their age. Generally, the mesolift
Aesthetic nurse Juan Lopez highlights cocktail can be changed for other cocktails, such as an anti-ageing
cocktail or a firming cocktail. For example, if you have an older patient
the benefits of using mesotherapy for you can change the mesolift cocktail for the regeneration cocktail,
facial skin rejuvenation which is better suited for older skin. The type of cocktail that I deploy
for this effect contains centella asiatica as the main ingredient,
Too often we focus our efforts on treating what patients request, believed to heal the skin, acting alongside dermal regenerative
without recommending or suggesting other treatments that would actives dexpanthenol, elastin and organic silicium, working to improve
improve their general appearance. In this manner, I believe that we are collagen fibres. If you have a younger patient, you can change to the
not working hard enough to care for our canvas. For us, as aesthetic radiance cocktail to help achieve glowing skin, which is what younger
practitioners, the canvas is our patients’ skin, and therefore treatment patients generally request. This protocol has been adapted from Dr
of this organ should always be our first recommendation. Good skin Britta Knoll.4
health makes our patients look better, and will also help to improve
the results of any other treatments implemented in the future, such as Pre-treatment Considerations
dermal fillers and botulinum toxin. If the skin looks better, the results Before considering any form of treatment it is crucial to take a
of other treatments will be greater. This is comparable to an artist’s thorough medical history, thereby ensuring mesotherapy is not
masterpiece – undoubtedly, any distinguished artist would ensure that contraindicated for any patient. This should be followed by a full
their canvas was of the best quality, to assist them in creating equally explanation of what the patient can expect, the length of time that
high-quality work. Likewise is true of caring for our patients’ skin. the treatment will take and the maintenance required to maintain the
For the purpose of improving the skin, I believe in following in the effects on the patient’s skin. The patient will need to be aware of the
footsteps of the French doctor Michel Pistor. In 1976, Dr Pistor first latter’s implications, commitment and potential cost in the long term.
described a technique involving injections of medications directly into Following consent, and as part of the protocol, it is necessary to take
the skin, also known as mesotherapy.1 The aim of mesotherapy in skin photographs of the patient and the skin condition at the first visit as a
rejuvenation is to maintain and restore a healthy and youthful texture. baseline, before commencement of treatment. This is also crucial in
The desired final effect is to firm, brighten and moisturise the skin by each session before the treatment in order to be able to monitor and
injecting suitable products that are biocompatible and absorbable document the progress of the results.2

Table 1: Mesotherapy Protocol for Skin Hydration


Product Composition Percentage of total mixture
Hyaluronic acid medium molecular weight Non-cross-linked hyaluronic acid MW 2% 30%
Nutritive complex for poly revitalising Hyaluronic acid, 10 vitamins, 25 30%
amino-acids, 2 co-enzymes, 4
nucleic acids, 2 reducing agents
Mesolift cocktail Hyaluronic acid, sodium DNA, 32%
multivitamins BCAE, organic
silicium, DMAE
Procaine Procaine 2% 20mg/ml 8%

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Further Treatments
As per protocol, the treatment continued for a total of four sessions. All

My protocol for sessions followed the same preparation, technique, dosage and post
treatment care as the first treatment. The sessions were booked every

mesotherapy for hydration two weeks, and photographs were taken before each session.

is to repeat this treatment Feedback and Outcome


Patient One reported after the first session that her skin had improved,

every two to three exceeding her expectations, and she claimed she felt her skin was
more hydrated. The greatest changes observed by both Patient

months, depending on the One and myself were after the third and fourth sessions. Patient One
described her skin as looking fresh and rested.

condition of the skin The last review session was four weeks following the final treatment.
At this session Patient One reported that previously her skin used to
feel fresh in the mornings, but due to the stress and nature of her job,
The Mesogun her skin would start to feel dehydrated again by mid-afternoon; with
As previously mentioned, it is important to distribute the same amount the mesotherapy she was noticing a fresher look lasting all the way
of product at the same depth in each injection. For that reason, we set to the evening. For her this was a very positive outcome and one that
up the mesogun to inject at 1mm depth and at a rate of 300 injections she wanted to maintain.
per minute. In my experience, patients find the treatment with the
mesogun more confortable than manual injections. A study by Duncan Treatment Maintenance
and Chubaty5 describes how some practitioners reported that use Patient One was keen to maintain the results. My protocol for
of a mesogun improved the patient’s experience and lowered the mesotherapy for hydration is to repeat this treatment every two to
perceived pain sensation. three months, depending on the condition of the skin. The skin is
reviewed after two months, after which a treatment is scheduled
Case Study accordingly, but generally is booked for the following month or earlier
Patient One is a 37-year-old female, who had visited my clinic if required.
previously to have treatment with botulinum toxin type A for facial
dynamic lines, hyaluronic acid (HA) fillers for volume replacement Conclusion
and a hydrating HA product for hydration of the skin. Previous skin In my experience, the use of mesotherapy for skin rejuvenation and
hydration with the HA product had had a positive effect but the patient hydration is a highly effective treatment. This kind of approach will
found that by the end of the day the skin was suffering and very benefit the long-term health and look of the patient’s skin. Other
dry. On previous occasions we had discussed the use of a course advantages cited by Tosti and De Padova7 include minimal pain and
of mesotherapy treatment for skin hydration in the area of concern. very reduced incidence of complications, and the treatment can be
Following consultation, the patient agreed to undergo four sessions of performed on every skin type with less downtime compared with other
mesotherapy for the whole face, as is the protocol used in my clinic. aesthetic treatments (e.g. microneedling). Both the patient and I agreed
the results on her skin had been favourable, consequently improving
First Treatment the patient-practitioner relationship/trust. With this in mind, aesthetic
Once Patient One’s skin was cleansed with chlorhexidine solution practitioners can confidently offer this treatment in clinic to maintain
and the mesogun preloaded, 5ml of the protocol mixture was injected patient satisfaction.
for a full facial treatment. It is always necessary to make sure that the
Juan Lopez is an aesthetic nurse and independent
patient is getting the product at the right skin depth. However, excess prescriber with more than five years of experience. His
product will remain on the skin, which will be absorbed if enough time special interests are skin health and mesotherapy. He is
is allowed before cleaning the skin. According to Patient One, the the owner of DermaTops.com and is preparing the launch
treatment was not painful with the exception of the top lip area where of his new clinic, Skin Medico, in London. Juan is also a
training consultant for Vida Aesthetics Ltd.
the treatment was slightly uncomfortable.
REFERENCES
1. Pistor, M., ‘What is mesotherapy?’, Le Chirurgien-dentiste de France, 46 288 (1976), p. 59.
The Injection Technique 2. Savoia, A., Landi, S., & Baldi, A., ‘A new minimally invasive mesotherapy technique for facial
The technique used during this facial treatment was ‘Nappage’. El- rejuvenation’,Dermatology and therapy, 3(1) (2013), 83-93.
3. Lacarrubba, F., Tedeschi, A., Nardone, B., & Micali, G., ‘Mesotherapy for skin rejuvenation:
Domyati et al6 describe this technique as quick and linear injections assessment of the subepidermal low-echogenic band by ultrasound evaluation with cross-
at superficial or mid dermis (1-4mm). 6 The volume injected should be sectional B-mode scanning’, Dermatologic Therapy, 21(s3) (2008), S1-S5.
4. Knoll, B. & Sattler, G., Illustrated Atlas of Esthetic Mesotherapy. (London: Quintessence
0.1ml for each single droplet, at a distance of a few millimetres apart. Publishing Company, 2012)
5. Duncan, D. I., & Chubaty, R., ‘Clinical safety data and standards of practice for injection lipolysis:
a retrospective study’, Aesthetic Surgery Journal, 26(5) (2006), 575-585.
Post Treatment 6. El-Domyati, M., El-Ammawi, T. S., Moawad, O., El-Fakahany, H., Medhat, W., Mahoney,
The treatment was finalised with the application of a recovery cream M. G., & Uitto, J., ‘Efficacy of mesotherapy in facial rejuvenation: a histological and
immunohistochemical evaluation’, International journal of dermatology, 51(8) (2012), 913-919.
and a broad-spectrum sunscreen (SPF 50). No bruising was observed 7. Tosti, A. & Pia De Padova, M., Atlas of Mesotherapy in Skin Rejuvenation, (London: Informa
immediately post-procedure or in the days following the session. Once Healthcare, 2007)

the treatment was finished, Patient One was advised not to wash her
face for a few hours.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Spotlight On: Kybella of subjects treated with Kybella experienced


injection site hematoma/bruising, and
cases of marginal mandibular nerve injury
were reported.4 These manifested as an
Following Kybella’s recent FDA approval for treating asymmetric smile or facial muscle weakness
submental fat, Aesthetics investigates the drug’s and resolved spontaneously from 1-298
days, with a median of 44 days.4 In addition,
efficacy and how it should be used in practice dysphagia (difficulty swallowing) occurred
in patients during the trials, with subjects
Double chins have long been associated body, which works to help the body absorb experiencing pain, swelling, and induration
with a displeasing aesthetic appearance, fat.5 The FDA explains that Kybella is a of the submental area. Again, cases of
with many consumers resorting to surgery cytolytic drug, which aims to destroy fat cells dysphagia resolved spontaneously, ranging
to remove unwanted submental fat. when injected into submental fat. Kythera from 1-81 days, with a median of three days.4
Now, however, a non-surgical alternative is claims that once destroyed, those cells Kythera advises practitioners to avoid
expected to cause a stir in the US aesthetic cannot store or accumulate fat.4 injecting into or in close proximity to the
market.1 In 2014, the American Society for Kybella is administered by injection into the marginal mandibular branch of the facial
Dermatologic Surgery (ASDS) reported fat under the chin, which can be tailored nerve, avoid using Kybella in patients with
that 68% of consumers are bothered by to individual patient requirements. Patients a current or prior history of dysphagia, and
submental fullness.2 This notably high statistic can receive up to 50 injections in a single take caution when treating patients with
is unsurprising says Dr Heidi Waldorf, director treatment, with up to six single treatments bleeding abnormalities, or those who are
of laser and cosmetic dermatology at Mount administered no less than one month apart. currently being treated with antiplatelet or
Sinai Medical Center in New York and a lead Dr Waldorf says, “Personally, I’m excited anticoagulant therapy.4 The company also
clinical investigator in the Kybella study. about the opportunity to offer my patients notes that in order to avoid potential tissue
“Many of my patients, both women and men, a clinically-proven, non-surgical option that damage, Kybella should not be injected
are looking for non-surgical options to help I can customise to the patient and their into or in close proximity (1-1.5cm) to salivary
treat their double chin,” she explains, adding, treatment goals.” glands, lymph nodes or muscles.4 It is
“the statistic is almost as much as those Research into the efficacy of Kybella further advised that the drug should not be
who say they are bothered by the lines and was supported by a global development injected outside the submental area or in the
wrinkles around their eyes [71%2].” programme, which included more than presence of infection at the injection site.7
Yet there seems to have been a distinct 20 clinical trials and 2,600 participants Upon reflection of the research discussed,
lack of non-surgical options for treating worldwide. More than 1,600 participants it seems likely that Kybella will have a
this ‘problem’ area – until now. Kybella, were treated with the drug, of which 68.2% substantial impact on the way in which
manufactured by US-based company responded to Kybella in the final phase III aesthetic practitioners approach submental
Kythera Biopharmaceuticals, is expected trials, compared to just 20.5% who were fat treatment in the future. And whilst there
to become available to US-based treated with the placebo drug.6 may be no plans to launch the drug in the
practitioners who have completed training Significantly, patients noted not only an UK in the near future, UK-based practitioners
in its administration this summer. As of yet, improvement in the amount of fat under can take this as an opportunity to follow
however, no filings have been submitted for their chin, but also an improvement in the Kybella’s overseas’ development and
the product to launch in Europe. emotional impact of receiving treatment. For learn more from our US-based colleagues
Despite this, the Food and Drug Dr Waldorf, this was very satisfying to hear; administering the treatment.
Administration (FDA) approval of the drug “As a cosmetic dermatologist, I want my
REFERENCES
has generated global news headlines. patients to feel better about themselves both 1. Damian Grade, Kythera FDA approval for its double-chin-
shrinking shot, (US: Fierce Biotech, 2015) <http://www.
The Telegraph reported that Kythera’s physically and emotionally,” she explains.
fiercebiotech.com/story/kythera-bags-fda-approval-its-double-
shares jumped by almost 8% following the The FDA enrolled 1,022 adult participants chin-shrinking-shot/2015-04-29>
2. American Society for Dermatologic Surgery, 2014 ASDS
announcement,3 whilst business analysts with moderate or severe submental fat
Consumer Survey on Cosmetic Dermatologic Procedures, (US:
have suggested that Kybella could bring in in its two clinical trials into the safety and ASDS, 2014) <https://www.asds.net/uploadedImages/2014%20
Infographic%20FINAL.jpg>
more than $300 million a year.1 efficacy of Kybella. Participants underwent
3. Gregory Walton, New cure for double chin approved, (UK:
Of course this is not only significant news for treatment with either Kybella or a placebo The Telegraph, 2015) <http://www.telegraph.co.uk/news/health/
news/11572510/New-cure-for-double-chin-approved.html>
investors in Kythera, it represents to many for up to six treatments and results
4. Kythera Biopharmaceuticals, Kythera Biopharmaceuticals
a new treatment option for those who are indicated that a reduction in the fat was Announces FDA Approval of Kybella (also known as ATX-101)–
First and Only Submental Contouring Injectable Drug,
unhappy with the amount of fat below their observed more frequently in those who
(California: MyKybella.com, 2015) <https://mykybella.com/wp-
chin. Submental fullness can affect both men were treated with Kybella.5 Each treatment content/uploads/2015/04/KYTHERA-FDA-Approval-Press-
Release-4.29.15-FINAL_.pdf>
and women – of any age or weight – and takes approximately 15 to 20 minutes and,
5. Food and Drug Administration, FDA approves treatment for fat
is often resistant to diet and exercise.4 “The according to Kythera, patients experience below the chin, (US: FDA, 2015) <http://www.fda.gov/
NewsEvents/Newsroom/PressAnnouncements/ucm444978.htm>
FDA approval of Kybella fills an unmet need visible results after two to four treatments.4
6. Kythera Biopharmaceuticals, Fact Sheet Kybella (deoxycholic
for physicians and patients,” explains Dr Up to six treatments may be administered acid) injection (US: Kythera, 2015)
<http://media.globenewswire.com/cache/23392/file/33701.pdf>
Waldorf. “Before this, there was an empty and once aesthetic response is achieved,
7. Kythera Biopharmaceuticals, Full Prescribing Information, (US:
spot in our therapeutic toolbox.” re-treatment is not expected.4 Kythera, 2015) <https://mykybella.com/wp-content/
uploads/2015/04/KYBELLA-Combined-FINAL-Labeling.pdf>
Also know as ATX-101, Kybella is identical to The drug does, however, come with
the deoxycholic acid that is produced in the reported side effects. In the clinical trials, 72%

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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A summary of the latest


clinical studies
Title: Outcomes of polydioxanone knotless thread lifting Title: A comprehensive health impact assessment and determinants
for facial rejuvenation of quality of life, health and psychological status in acne patients
Authors: DH Suh, HW Jang, SJ Lee, WS Lee, HJ Ryu Authors: C Pagliarello, C Di Pietro, S Tabolli
Published: Dermatologic Surgery, June 2015 Published: Giornale Italiano di Dermatologia e Venereologia,
Keywords: Thread lifting, non-invasive, facial rejuvenation June 2015
Abstract: Thread lifting is a minimally invasive technique Keywords: Acne, health, psychological impact, effects
for facial rejuvenation. Various devices for thread lifting using Abstract: Acne adversely affects all aspects of quality of life (QoL).
polydioxanone (PDO) are popular in aesthetic clinics in Korea, Although many papers assessed acne-specific QoL impairment, there
but there have been a few studies regarding its use. The objective are few data on its impact on general health and psychological status.
was to describe PDO thread and techniques adopted to counteract Apart from acne severity, little is known about determinants of a
the descent and laxity of the face. A retrospective chart review worse QoL. The aims of this paper were to measure acne impact on
was conducted over a 24-month period. A total of 31 thread QoL, health and psychological status and to analyse the relationship
lifting procedures were performed. On each side, 5 bidirectional between socio-demographic variables, disease severity and mental
cog threads were used in the procedure for the flabby skin of status on QoL of acne sufferers. Acne cases were selected from a survey
the nasolabial folds. And, the procedure was performed on the conducted in 2010. The Short-Form 12-Item Health Survey and the
marionette line using 2 twin threads. In most patients (87%), the Skindex-29 were used to assess health status and QoL. The 12-Items
results obtained were considered satisfactory. Consensus ratings by General Health Questionnaire was used to identify individuals at risk
2 physicians found that objective outcomes were divided among for non-psychotic psychiatric disorders (GHQ-positive). Physician
“excellent,” “good,” “fair,” and “poor.” Texture wise, the outcome (PhGA) and patient global assessments were obtained. We investigated
ratings were 13 as excellent and 9 as good. Lifting wise, ratings were the variables involved in the QoL through a logistic regression analysis.
11 as excellent and 6 as good. The incidence of complications was One hundred ninety-five cases were analysed. Twenty-six percent were
low and not serious. In conlusion, facial rejuvenation using PDO GHQ-positive; acne’s impact on health status was worse compared to
thread is a safe and effective procedure associated with only minor other chronic diseases. A GHQ-positive status (Skindex-29 overall:
complications when performed on patients with modest face OR 2.6; 95% CI 1.20-5.60, P<0.05, functioning: OR 2.5; 95% CI
sagging, fine wrinkles, and marked facial pores. 1.17-5.44, P<0.05, symptoms: OR 3.0; 95% CI 1.36-6.53, P<0.01;
emotions: OR 2.55; 95% CI 1.19-5.46, P<0.05) and having a severe/
Title: A novel non-invasive radiofrequency dermal heating device very severe PhGA (Skindex-29 overall: OR 3.4; 95% CI 1.20-10.38,
for skin tightening of the face and neck P<0.05) were associated with a poor QoL. Age of onset >25 was linked
Authors: AA Nelson, D Beynet, GP Lask to being GHQ-positive (OR 2.92; 95% CI 1.2-7.1, P<0.05) controlling
Published: Journal of Cosmetic and Laser Therapy, May 2015 for gender, marital status and educational level. Acne is not a minor
Keywords: Non-invasive, radiofrequency, rejuvenation, skin disease in comparison with other chronic conditions. Age of onset is
tightening capable to influence GHQ status which in turn affects QoL.
Abstract: Loose, lax skin is a common cosmetic complaint.
Previous non-invasive skin tightening devices had modest efficacy Title: Effective protection of biological membranes against photo-
and were associated with pain or downtime. New technologies may oxidative damage: Polymeric antioxidant forming a protecting shield
allow for effective skin tightening with a series of no downtime, over the membrane
radiofrequency treatments. The objective was to evaluate the Authors: O Mertins, PD Mathews, AB Gomide, MS Baptista, R Itri
efficacy and safety of a novel bipolar radiofrequency device for skin Published: Biochimica et Biophysica Acta (BBA), June 2015
tightening. 15 consecutive female patients were enrolled in the case Keywords: Gallic acid, photodamage, biological membranes,
series; 14 completed the study and were included in the analysis. oxidative stress
The device under investigation is a novel, bipolar radiofrequency Abstract: We have prepared a chitosan polymer modified with
device allowing for achievement and maintenance of optimal dermal gallic acid in order to develop an efficient protection strategy for
temperatures to stimulate collagen remodeling and skin tightening. biological membranes against photodamage. Lipid bilayers were
Patients underwent a series of 4-6 weekly treatments. Three blinded, challenged with photoinduced damage by photosensitisation with
experienced cosmetic physicians evaluated paired blinded pre- methylene blue, which usually causes formation of hydroperoxides,
treatment and post-treatment photographs and determined the increasing area per lipid, and afterwards allowing leakage of internal
associated improvement, if any. All patients (14/14) were determined materials. The damage was delayed by a solution of gallic acid in
to have a clinical improvement, as the pre-treatment and post- a concentration dependent manner, but further suppressed by
treatment photos were correctly identified by the evaluators. 21% the polymer at very low concentrations. The membrane of giant
(3/14) patients were observed to have significant improvement, 50% unilamellar vesicles was covered with this modified macromolecule
(7/14) observed to have moderate improvement, and 29% (4/14) leading to a powerful shield against singlet oxygen and thus
had mild improvement. No pain, side effects or adverse events were effectively protecting the lipid membrane from oxidative stress. The
observed. This novel bipolar radiofrequency device represents a safe, results have proven the discovery of a promising strategy for photo
effective treatment option for non-invasive skin tightening. protection of biological membranes.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Why you shouldn’t


ignore online clinic
reviews
Emily Ross, director of communications at
WhatClinic.com, helps you to make the most
of online reviews in order to acquire and
retain new patients

The internet has completely disrupted the that are categorised as ‘Local Businesses’, allowing people to post reviews and
‘rules’ of traditional marketing. Whilst emphasis ratings onto your page. Although you don’t get to decide which reviews are
was previously, for the most part, placed on the published, you can, however, complain to Facebook if a review doesn’t meet its
interaction between the business and the consumer, community guidelines.6 These guidelines stipulate that content may be removed
the dialogue between consumers themselves is if of a threatening or violent nature, or if activity constitutes bullying or harassment.
gaining increasing importance, with online review Users can choose to switch off reviews if it’s more than they can handle. The best
sites at the forefront of this ‘consumer to consumer’ approach to Facebook online reviews, indeed to all online reviews, is to handle
(C2C) marketing revolution. With more online review them appropriately. Here I’ll share some simple guidelines for effective review
sites popping up every day, understanding how they management.
work – and how to maximise them for your business
– is essential. Clinics can either spend time reacting Seven steps for handling a bad review
to the fall out or, at best, spend time turning this No matter what business you’re in, if you deal with members of the public you’ll
disruption to their advantage. What they cannot do probably agree that most people are quite reasonable. But there are some
is simply ignore them. Access to this new world of exceptions, and, unfortunately, it’s the exceptions that tend to make the most noise.
C2C marketing is never far away. With the touch of While online review sites can be a great space for people to share and read positive
a screen on a smartphone, consumers can access a opinions, it’s also the perfect forum for a small number of people to cause business
number of platforms where they can gripe, moan and owners a real headache. So, how should you deal with negative comments?
criticise via words, photos and even high definition
video. Let’s take a look at some of the review 1. Actually read the review
platforms available in the UK. Try and be impartial. Remember that every review is written by a real person, who
In recent years, Google has added Google Reviews came to you seeking help. Criticism is always hard to take, but is there anything
to its portfolio.1 With both Google Maps and the you can learn from this review? Is there a grain of truth or more in what was said?
colossal brand power behind this product, it’s not Irrespective of the medium in which the complaint is made, it is incredibly bad
to be ignored. Now your clinic is just as likely to be practice to disregard feedback from a paying customer.
listed on here as in the phone book. Once you have
verified your business on Google+, you can then 2. Respond – the sooner, the better
respond to these reviews. Google has also made it We’re all human, and we can sometimes let our natural defensiveness play out. If
particularly easy for people to leave Google reviews you feel very strongly about a review, think before you respond. Wait until the next
via their smart phones. morning, and try and reply in a professional manner, and as calmly as possible.
WhatClinic.com Reviews launched in 2008. The site Or, if you can’t trust yourself to be calm, get someone else to sense-check
lists more than 100,000 clinics, including medical your response before you post it online. A moment of anger may damage your
aesthetic, plastic surgery and private hospitals in reputation, and can leave a lifetime of regret.
more than 120 countries.2 It has also recently added
photos and videos to its review content. It provides 3. Never, ever include private patient data in your response
clinics with tools and apps to get the most out of An obvious one, you’d think, but most clinics are caught out by what is actually
patient reviews. classified as ‘private’. Any information relating to an individual’s visit, including
Facebook Pages3 also provides a review feature the date, time, gender, and treatment choice might be considered confidential
for businesses, as launched in 2013.4 This is proving information. Essentially, anything that is specific to that patient. ‘When you visited
more and more popular, with the number of small our clinic last Tuesday’ is an excellent example. This very general sentence is
businesses using Facebook Pages rising by 10 personal, because it refers to the individual. Speak only on general policy and
million in just one year.5 It is enabled for pages practice in your public answers.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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4. Handle it offline as outlined in the Defamation Act 2009 (which came into effect
This is the first recommended action for managing any disgruntled in 2010).7 No matter where the location of the clinic that is being
patient review. There are times when email conversation can reviewed is, as the publisher, WhatClinic.com must adhere to Irish
make a bad situation worse. Email has a dehumanising effect, and, law. This means all of these reviews are verified, both by phone and
because of this, it’s easier to be irate in email dialogue. By picking by email, to confirm they come from real patients.
up the phone and making the effort to speak to the customer, and Then, a moderator actually reads the review to ensure that it’s
with the effort of simply listening to them, many frustrations and not offensive, malicious or defamatory. It means a considerable
miscommunications can easily blow away. number of reviews don’t make the grade and cannot be published,
but we work hard to engage with patients to help them get their
5. Take time to listen point across in a frank and honest manner, which meets our review
As we all know, in any complaints process, having someone listen guidelines.
to us and empathise is the first step to resolving any dispute. In your
online comments show that you are really listening and empathising Negative reviews only have power if they stand alone
with the patient who has taken the time to provide feedback, before When you think about it, one or two poor reviews beside a hundred
inviting the person to contact you directly. great ones are actually not that bad. In fact, they can be quite
reassuring to the consumer, because it shows that these are indeed
6. Don’t ‘fob them off’ genuine reviews from real patients. Realistically, if no one provided
Referring the user to information on your website or brochure page any constructive criticism, would you really trust the forum?
is a good idea only if the specific issue is clearly and succinctly dealt Many would argue not. How you handle a bad review is often of
with in your website or brochure. But, let’s face it, very few websites more interest to other readers than the actual complaint.
are as well laid out as they should be, and it may be harder than Every poor review is an opportunity for you to show off your
you’d imagine to find the one little nugget of information that is customer care, your patience and your empathy, and you shouldn’t
relevant or important. Making the user feel as though it’s their fault lose sight of that. On our site, we have found that clinic listings with
that they haven’t been able to find the relevant information might lots of reviews are more popular than those without. There are lots
only fuel their irritation. of ways you can encourage patients to leave reviews:

7. Don’t be surprised if… 1. Put a link to a review site in the bottom of your emails or on your
People publicly post your private responses to them. That’s okay website
– they have the right to broadcast your responses. Unfortunately, 2. Email customers and ask them politely if they would like to review
you don’t have the same privilege. Don’t be surprised if irate your clinic
customers say things that aren’t true, frame responses negatively, 3. Add suggestions to receipts and in promotional material that you
or are downright offensive. Also, don’t be surprised if someone welcome patient reviews
who is very angry doesn’t bother responding to your carefully
crafted comments, or polite invitations to discuss the issue. In these It’s also a great idea to maximise the value of online reviews
cases, let your last words be the ones to remember. Remain calm, and market them to your benefit. Why not share your favourite
be pleasant, utterly professional and always well-mannered. This is reviews on your social media platforms, or to add them to your
what will last in the mind of the reader – no matter what the initial website, brochures and point of sale? As a means to really get to
complaint. understand your patients as consumers, reviews can give you a
window into how real patients view your business. That information
Dealing with malicious reviews and trolling can often be worth its weight in gold. Whilst online reviews have
Negative comments and complaints are one thing, but there’s a fine led to an increased power of C2C marketing,8 remember that it’s a
line that can be crossed. Have you heard of internet trolls? This is conversation that you too can very easily, and effectively, engage in.
the term I would use for a person who starts online arguments or
Emily Ross is the marketing and communications
upsets people by posting inflammatory or off-topic messages in an director of WhatClinic.com – a search engine that
online community, in order to provoke an emotional reaction from lists more than 100,000 private clinics worldwide. She
fellow contributors and readers. The very best advice is: do not feed is a regular speaker and lecturer on social media and
the trolls. Some people are so provocative, and so clearly driven by digital marketing.
malice, that their own comments are enough to ensure that no-one REFERENCES
1. Get Reviews on Google (US: Google, 2015) <https://support.google.com/business/
takes them seriously. By engaging in an online back-and-forth you
answer/3474122?hl=en-GB>
are simply playing into their hands, and potentially causing more 2. About (Ireland: WhatClinic.com, 2015) <http://about.whatclinic.com>
3. Josha Sophy, Facebook enables starred reviews for some businesses (US: Small Business
trouble than it’s worth. It’s also incredibly difficult to engage with
Trends, 2013) <http://smallbiztrends.com/2013/11/facebook-starred-reviews.html>
people who are purely out to stir and cause argument without losing 4. Anthony Ha, Facebook Says There Are Now 40m Active Small Business Page (US: Tech Crunch,
2015) <http://techcrunch.com/2015/04/29/facebook-40-million/#.eqpw5y:74fl>
your cool, which sends out the wrong message on a public space,
5. What Happens After You Click “Report” (US: Facebook, 2015) <www.facebook.com/notes/
and can damage your brand. Check to see if their content warrants facebook-safety/what-happens-after-you-click-report/432670926753695>
6. Defamation Act 2009 (Ireland: Houses of Oireachtas, 2009) <www.irishstatutebook.ie/pdf/2009/
a complaint to the host of the review site (if their comments are
en.act.2009.0031.pdf>
clearly untrue, for example) and in the meantime, leave well alone. 7.  Myles Anderson, Local Consumer Survey 2014 (US: BrightLocal, 2014) <www.brightlocal.
com/2014/07/01/local-consumer-review-survey-2014/>
Most review sites provide you with means to flag malicious content,
such as the report button on Facebook,6 and many companies will
have their own guidelines that must be adhered to. WhatClinic.com
is based in Ireland where defamation law is extremely stringent,

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

Enhancing the
patient journey
Clinic operations director Deborah Vine
outlines how her team works to provide
the best experience for patients on their
treatment journey
The regulation of cosmetic surgery and Going Digital
associated treatments has been under the Today, clinics must ensure that they convey a clear, consistent and informative
spotlight for a good few years. Press coverage message across all mediums. Attention to detail in all areas has become vital
has sparked conversation at all levels, especially as businesses have several ‘windows to the world’, and each should reflect the
online via social media and forums, and, in turn, this consistent service level that the patient can expect throughout their experience.
has heightened awareness surrounding aesthetic Digitally, video and blogging have become very useful ways to prepare the patient
treatments. The demand for clearer information is for what they can expect. One very popular project we commissioned at Karidis
now huge, and this demand has been answered Cosmetic Surgery London was a video of our customer journey. We wanted people
by an increase in information on television, online to feel comfortable with where they would be coming to take away any uncertainty.
and through media coverage. Perhaps due to During the video, they pass through the doors of our clinic, where our reception desk
this scrutiny, patients are now more informed, is situated, then see other patients sitting in our waiting area, followed by clips of a
and ask more questions. However, despite this consultation. Later in the video, the viewer will see what the hospital room would
growing confidence, we must not lose sight of look like on the morning of a surgical procedure, with a patient in a gown and robe
their primary reason for visiting us – often this is discussing their procedure pre-operatively. We believe all of this will help to break
because something about their body is causing down barriers and make the patient feel at home, and the beauty is that they can
them concern, embarrassment, frustration, or worse. experience this in their own home where they are already at ease. Although the video
Making that first enquiry will have taken courage is an effective visual aid, some patients would rather read hard facts. In this case, we
and will not have been taken lightly. Throughout this found that some information was easier to document in a written format, so to reflect
entire experience, each patient may feel completely this, we created a surgical and non-surgical patient journey guide which is featured on
outside of the realms of comfort, and we must our website. It gives a step-by-step guide of how to get to us, where to park, and what
consider this at every point of their journey and craft to consider, in order to resolve any uncertainty.
our responses to their queries carefully.
Interaction
The Journey Each time there is interaction with a patient, be it digitally, via email, telephone, letter or
There are numerous feelings and considerations personally, it triggers a touch point. Each one should be considered carefully, ensuring
which affect the decision process in our potential that clarity, simplicity, information and business identity have been considered and
patient’s mind. Our role is to carefully de-construct well represented at all times. In giving patients consistency we nurture their trust,
this, identifying and stripping back any potential and the patient will feel reassured that they are in safe hands if our message and
barriers, whilst always ensuring that the patient’s service remains the same throughout their experience. Any doubt can lead to a lack
best interests remain at the centre of everything we of confidence and make things difficult. Of course, some patients would prefer to
do. Our objective is to make each experience along approach the clinic by more traditional methods such as calling or dropping by. My
the way as simple as possible, allowing the patient entire team mystery shop other clinics at least once annually with the objective of
to focus on getting all of the information that he or putting themselves into the patient’s shoes. They look at presentation, information and
she needs in order to help them make an informed cleanliness. However, what is more important is that they truly feel what our patients
decision about treatment with a clear mind. The feel. There are some great clinics out there and it is so good to hear when my team
patient journey begins with the patient identifying return full of inspiration. The exercise is about more than information gathering as it
their concern and taking the decision to act. This forces the team to examine how they talk to people and react to situations; they also
must be where our journey also begins. As a team, feel the nervous anxiety when they are waiting to explain to someone what they least
we must make things as easy as possible for them like about themselves, and how the attitude of those they come into contact with can
and should consider some key questions. Where influence this experience. The ambience in waiting areas varies hugely, and trying to
might they hear about us? How might they find us? reflect your brand image and showcase your offering whilst creating a comfortable
How are we represented and, more importantly, and inviting area can be challenging. Patients can also be waiting a considerable
how much can they learn about us? Are we amount of time, so essentials like cleanliness and comfort are basic but vital things to
encouraging them enough to take a further step? get right in order to avoid a bumpy first meeting. Interaction and information are also

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

key considerations here. We feel it is important that the reception team Moving On
do not use the reception desk as a barrier. When a patient arrives the Keeping in touch with our patients is key to the success of our
receptionist should come around from behind the desk to welcome business. The team are instrumental in how often people are
them, and, if needed, put the patient at ease. They also must ensure contacted and, again, this can be through various methods including
they keep patients abreast of any changes, as time is precious to us all. social media, online forums, newsletters and emails to keep people
Little touches are always the icing on the cake; they do not have to cost informed. One of our main ways to engage with patients is through our
much but do make a huge difference. Detailed follow-up calls, skincare events and gatherings. We host information evenings for our patients
tips, a personal visit from our own surgeon, Mr Karidis, following their and potential patients with speakers well-established in the aesthetic
surgery – these things all add to the experience. Within our clinic, Mr field to discuss topics and treatments, and to answer any questions.
Karidis sends each of his surgical patients flowers, which are waiting Mr Karidis is always on hand at these events to offer new, insightful
for them in their room when they return from theatre. This is just a small information, but, most importantly, will utilise the opportunity to interact
gesture, but one that is always well received. with each attendee. We believe this is vital to help people see that he
respects and understands how important these social events are, as
Striving For Improvement well as the private consultation. We strive to ensure that our events
Receiving feedback, whether positive or otherwise, is always a offer an ‘open door’ policy; where nothing is hidden from attendees
blessing. Through our patient satisfaction surveys, we are able to who wish to learn more. Participation and excellent communication
nip dissatisfaction in the bud and formulate plans to make future make the journey through our clinic smoother for the patient. Keeping
experiences even better. Making time to listen to our patients is crucial patients informed and making them feel comfortable and reassured
to giving our clinic heart. Although feedback may occasionally not at every point, increasing their confidence in the practice and allowing
be as positive as you had hoped, it is also a starting point to help you them to break down their barriers and communicate effectively is key.
overcome future situations and build upon solid foundations. Any Surveying our patients about what they like and getting them involved
patient dissatisfaction is discussed at our weekly meetings and, as a in our future choices and the way we do things has formed a huge part
team, we work out how to resolve them with the best possible outcome of our plans for 2015, and will be evident in the direction our business
for all. One question I have asked my team is to imagine they were takes in the coming years. Our goal is to continue to make it easy for
considering surgery; what are the questions that they would want to ask, people to glean all the information that they need for making informed
but feel too embarrassed (or too foolish) to ask? Their questions were decisions, with a very good idea of the agreed potential outcome. With
sometimes personal and sometimes so obvious that we have never increasing demands and ever changing expectations there will always
addressed them in our patient journey information. Results from these be room for improvement, however by actively engaging our team
sessions have formed the basis of how we plan to move forward. It is a and keeping things simple, approachable and accessible, the patient
very good exercise and has really got the team to think like our patients. journey becomes a harmonious experience for all.

Clinical Consultation In Practice


Once a patient gets to the stage of consultation and treatment, “Surgery is a big step for most people, and making
Mr Karidis, supported by our clinical and admin teams, works hard
this decision is associated with a host of different
to ensure that each detail is addressed and that outcomes are
emotions, such as fear and anxiety. We always try to
discussed to make sure there are no surprises. Only once the
reassure patients as best we can, keeping open channels of
patient has been fully consulted do they meet with an administrator
communication even after the consultation, so in the event of
to discuss logistics and pricing. This is a major part of the customer
any uncertainty they can quickly get their questions answered.
journey and a huge step for each patient, which is why it is absolutely
We hope that this all leads to a very reassured atmosphere for
vital that each patient meets Mr Karidis so he can assess and advise
them as individuals, based on his knowledge and experience. the patient, which makes them feel safe in our hands. When
Patients invest a lot in this process, not just financially but also with armed with proper information, patients can make a properly
trust, with the added potential of exposing a plethora of feelings informed decision about whether or not surgery is for them. From
including guilt, fear and anxiety. A patient meeting their surgeon the moment a patient begins to contemplate possible surgery,
and the supporting team with whom they are investing is integral to that’s when the journey begins. We as a practice and collective
the journey within our clinic. Results of our mystery shop also allow team have the ability to favourably influence this patient journey
us to gauge follow up after a consultation. However, there is no at various points in order to make it as seamless, painless and
industry formula here – we all want patients to feel cared for, but not comfortable as possible. If we can end that journey with a happy
harassed. In our experience, many clinics do not appear to follow and satisfied patient, then we can consider that we have done our
up at all. From their mystery shops, members of my team reported job well. Many return for other treatments, and this is a testament
that they liked a clinic who sent a well constructed personal email to our skills in being able to offer a great patient journey, which in
which thanked them for coming and sign-posted that a call would be turn gives our team great job satisfaction.”
made in a week’s time to discuss matters further, but that also gave Mr Alex Karidis, founder of Karidis Cosmetic Surgery London
an option to decline this call. This ensures there are no surprises
and that patients have the choice to opt out easily. Following their Deborah Vine is director of operations at Karidis.
procedures, our clinic has many patients who want to share their She has a wealth of experience creating comfortable
positive results with others. What is fantastic for us is that these environments for people to recognise and achieve
their personal goals. With a career spanning across a
people become ambassadors for our clinic and at prearranged times
plethora of industries and high profile brands, Deborah
will talk to prospective patients, with a view to providing reassurance has worked to develop a deep understanding of the emotional
and answering any questions they might have. decision-making process.

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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Social
Media
Etiquette
Paul Jackson aims to eliminate the
possibility of committing a social
media faux pas with his guide to
communicating concisely and
effectively online
Social media is forming an increasingly important part of aesthetics on social media is one of main reasons that social media users stop
clinics’ marketing and customer relations. It is a valuable way to following or engaging with people or businesses.1
convey your personality, to converse and increase awareness of your A clever trick to use here is to determine the days of the week and the
services with potential and existing patients, as well as to encourage times of the day that your social media posts are generally seen the
feedback and word of mouth recommendations. most and receive the best response. Facebook, Twitter and Pinterest
With so many businesses seeing the potential of social media, there all make this data available to you for free via their analytics sections,
is a great deal of competition in terms of clinics vying for patients’ and free online tools such as Hootsuite and Pagemodo can be used to
attention. Social media users are therefore becoming more and more help you schedule your posting on other social media sites. Use your
picky about who they follow and who they engage with online. So analytics data to schedule your posts for these times, keeping in mind
whilst social media presents huge opportunities to build and interact that quality always beats quantity on social media.
with your audience, it can also be a swift way of alienating them if Through analysing this data you will also learn about your audience
you’re not doing it effectively. In everyday face-to-face interactions and you’ll start to see trends developing. For example, from my
if somebody is self-centred, waffling, moaning, talking too much, experience of the aesthetics industry, it is common to see social
or talking about things you’re not interested in, you’re unlikely to media engagement peaking at lunchtime, during end of school
give them too much of your time, and it’s exactly the same scenario time whilst people are waiting to pick up their children, and in the
online. Establishing good social media etiquette is crucial, and falling early evening when people might be making their train journeys
short in this respect can cause you to lose followers faster than you home, as well as later in the evening (perhaps when people are
are gaining them. This article aims to ensure that you are not only browsing online in bed).
meeting expectations, but standing out as a glowing example of how
to behave and succeed on social media. It’s Not What You Said…
As well as considering what to say and when to say it, tone of voice
It’s Not About You is critical to your social media success. One of the limitations of
A common misconception regarding social media is that it is a communicating online is that it can be difficult to understand the
platform for voicing your thoughts, detailing the events of your day- intended tone of a post, and tone can often be misinterpreted.
to-day life, and promoting your products and services. This is what Take time to determine exactly how you want to be perceived. As
a large proportion of businesses on social media are doing, but this an aesthetic clinic or practitioner you are likely to want to come
completely disregards its ‘social’ element. across as friendly and approachable, understanding and caring, and
Instead, think of social media as a platform for engaging with your knowledgeable and trustworthy. This can go a long way to securing
audience, learning about them, and offering them genuinely valuable your first bookings from potential customers, or further bookings
content and insights. It’s all about your target audience and what they from existing customers. Think about whether your post could be
want to read about or view. A good rule to follow is the 80:20 rule – for misinterpreted, especially if you are making a light-hearted comment,
every two posts that are directly about you or your businesses, eight and take steps to make the intent clear.
should not be and should instead be conversing directly with people,
providing useful resources, or commenting on relevant topics. Knowing Where to Draw the Line
There have been a number of well-publicised news stories of incidents
Pace Yourself where people have said things they shouldn’t have on social media,
We all want our posts and content to be seen by our audience, and such as celebrities commenting on stories that were under super-
the more we post, the more visible we’ll be. However, over-posting injunctions.2 In the aesthetics industry, two potential minefields are

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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patient confidentiality and giving medical advice online. and schedule posts in advance, such as the ones mentioned
In the informal and conversational setting of social media it can previously. These tools typically offer you the option to type out
be easy to feel like you are in ‘off the record’ discussions, but a post and then send it out across all your different social media
professionalism and ethics should always be at the forefront of your profiles in one go.
mind. Whether it’s a quick mention of a celebrity patient who has Despite being an effective time-saver in many cases, bear in
just been in for an appointment, or making treatment or procedure mind that different types of posts and different wording are more
recommendations without a face-to-face consultation, give these effective on different social media sites. For example, short and
topics a wide berth and err on the side of caution when in doubt. snappy posts typically perform well on Twitter, whilst image posts
Social media is also a place to show sensitivity and awareness. tend to perform strongest on Google+, and more insightful and
Many people who are considering an aesthetic treatment, and even professional content is usually better on LinkedIn. A less formal
those who have them regularly, are shy, embarrassed or wary about approach normally has greater appeal on Facebook.3
publicising that fact. Following and initiating contact with your patient Social media management tools are a valuable asset and allow
and customers online can bring the relationship to the attention you to save time and improve the quality of your activity – the key
of others when they would prefer it was kept private. Instead, is to remember to keep tailoring and personalising what you are
encourage them as much as possible to follow and contact you via doing. It’s better to focus on hitting the mark on one social media
messaging on your website, in emails, in your clinic and in person. channel than missing it on several channels.

Professional vs Personal Avoid the Hard Sell


Another area where social media’s blurred lines can limit your At the end of the day, businesses and professionals are using
success is when it comes to deciding whether you are posting social media to build or retain their patient base, or to achieve
personal or professional content, and this is a particularly tricky other goals that will contribute to that, such as building their
issue in aesthetics. Many clinics and practices are built on the skills, reputation, status and visibility. Social media really is a marathon
reputation and brand of an individual, whilst some practitioners are and not a sprint so it is important to avoid jumping to the end goal,
connected with multiple clinics or practices. When people decide to whether that is convincing a new patient to book a consultation or
follow a clinic or a professional they don’t expect to see posts that generating repeat business from an existing customer. In a face-
are far removed from the aesthetics industry. On sites such as Twitter, to-face meeting, it would be too abrupt to meet somebody for the
it is better to have a professional or clinic profile and a separate first time and to start pushing your products and services to them,
personal profile in order to separate the two and ensure the right and the same applies on social media. Play the long game, build a
types of content are being posted on each. relationship, get to know your audience, let them get to know you
and trust you, and naturally they will make their decisions about
Speak Their Language you and your services. Sure, you can help them along the way, but
Your target audience is likely to have a range of knowledge levels, continually painting the best picture of yourself and your business
from those who are new to aesthetic treatments through to those who is the key, rather than promoting a sales pitch.
have experience of a range of procedures. In technical and medical
industries it is easy to fall into the trap of using acronyms, niche The Key Takeaways
phrases and little-known brand names in your social media content. Meeting and exceeding expectations for social media etiquette
If a user does not understand your posts, they are unlikely to engage essentially boils down to a very simple set of considerations.
with you or share the post. It also gives the impression that your • It’s not about you or what you are interested in talking about,
business is not in sync with customer needs. Keep in mind that your it’s about your audience and what they are interested in you
target audience is not likely to consist of other aesthetic professionals, talking about.
so post content that will appeal to your potential and existing • Before posting anything on social media sites, ask yourself: should I
customers, rather than other people in the industry. be posting this, who would want to see this post, what value does it
offer them, and what response do I want?
#Overuse #of #Hashtags • Social media is just like an offline conversation or friendship.
There are numerous bad habits that you’ll come across online, Nobody wants to stay and talk to the person who talks too much
and overuse of hashtags is a common sight along with people and only about themselves, so be the listener, the helper, the expert
creating their own hashtags unnecessarily. Hashtags are designed – the person everyone wants to talk to.
for categorising social media posts. If somebody is interested in
Paul Jackson is senior marketing consultant at
a certain topic, a certain news story, or a certain person, hashtags Reload Digital and specialises in social media and
allow them to see all the posts that related to what they are online marketing for the aesthetics, beauty, cosmetics
interested in. My recommendation would be to have no more and fashion industries. As a chartered marketer and
than two hashtags in a post. When deciding on a hashtag to use, Google certified partner, Paul can be seen speaking at
marketing events across the country.
consider what it is that people will be searching for when they
might like to see your post. When a post has too many hashtags REFERENCES
1. Carr, D, Why do people unfollow you on Twitter (www.marketingtechblog.com, 2012)
it suggests that there is no real value in the post itself and it can <www.marketingtechblog.com/twitter-unfollow/>
cause them to be overlooked and ignored. 2. BBC News, Alan Davies pays Lord McAlpine damages over tweet (UK, www.bbc.co.uk,
2013) <http://www.bbc.co.uk/news/uk-24654289>
3. Betancourt, L, How to optimise content for social media (engage.scribblelive.com, 2014)
Be Wary of Shortcuts <http://engage.scribblelive.com/Article/704594-How-to-Optimize-Content-for-Social-Media)>

There is an array of free and premium social media tools available


online to help you to manage your social media presence

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


@aestheticsgroup Aesthetics Journal Aesthetics aestheticsjournal.com

“You are never too good or too


old to learn something new”
Beverly Hills dermatologist Dr Zein Obagi has been an
outspoken figure in the skincare world for more than
three decades. Wendy Lewis talks to him about his
considerable achievements in skin health
Researcher, lecturer, author and board-certified dermatologist, Dr The Art of Skin Health Restoration and Rejuvenation: The Science
Zein Obagi is considered by many to be a pioneer in advanced of Clinical Practice. To carry on his legacy, he has handpicked a
skincare, and one who has broken new ground at every stage of special group of physicians from the US and all over the world to
his career. His innovations in pigmentation disorders and chemical join the ZO Faculty. This elite group of skincare experts, including
peels in particular are widely respected throughout the specialty. plastic surgeons, dermatologists and cosmetic doctors, lecture and
Dr Obagi’s interest in skin health began early on. He took a circuitous conduct research on skin health, based on Dr Obagi’s experience
route into dermatology, having started out as a pathologist dealing and teachings. In May 2015, the first of many planned ZO Skin
with diseased tissues. “I found my true calling when I embraced Centres opened in the Fashion Island shopping centre in Newport
dermatology as my specialty,” he says. Beach, California. The model, which is the culmination of his vision,
“A baby’s skin always fascinated me. Microscopically, each cell incorporates all of Dr Obagi’s current thinking about skin health and
is fulfilling its precise function, which corresponds to its flawless features an integrated offering of facials, peels, and advanced anti-
appearance. As a physician, I wanted to offer this possibility to all ageing treatments with his signature products. Despite all of his major
patients. The fundamental principle driving my approach is that achievements, for Dr Obagi family will always come first, having raised
skin must be holistically restored at the cellular level. If the focus nine children with his partner Samar. Now in his seventh decade, Dr
is limited to treating only the disease or its symptoms, the results Obagi has the energy and sharp intellect of a man half his age, and
will be limited and short-lived,” he says. In 1983, Dr Obagi was shows no signs of slowing down.
instrumental in pioneering the concept of skin health for the mass
market, and developed a line of medical skincare products – the What is your core philosophy for educating healthcare
original Obagi Nu-Derm System – that aimed to transform ageing professionals?
skin. Of that time, he says, “My intention was to challenge the norms I want to get the message across that skin health restoration
of traditional skincare.” His goal was to take the confusion out of can’t be accomplished by products alone; the physician needs to
skincare for patients by maintaining the stature of physicians, nurses know how to use them in the most effective way, through step-
and aestheticians as the true skin care experts. “Who better to know by-step treatment protocols.
how to maintain healthy skin and treat disease?” he asserts. Today
many of his ideas about skin health have become mainstream. Dr What is the biggest mistake patients make with their skin?
Obagi founded the Obagi Skin Health Institute in Beverly Hills in 1985 They get bad advice, use the wrong products, and over
as a comprehensive dermatology practice exclusively dedicated moisturise their skin which makes the skin weaker instead of
to advanced skin treatments, where he still sees patients from all strengthening the skin. The skin cells get lazy and it actually
makes them look older. When they come to us, we take them off
over the world. The Institute has since expanded to three additional
moisturisers and put them on a regimen of products to restore
locations; Laguna Niguel, San Gabriel and Pasadena, California.
skin health.
The trio of Obagi Skin Health Institutes in Southern California are
stunningly modern facilities. These state-of-the-art clinics offer a full Who is the driving force behind your great success?
programme of cosmetic and medical treatments, as well as luxurious Without a doubt, my wonderful wife Samar is my biggest fan. She
spa therapies. After his original company, WorldWide Products, is a very talented businesswoman and has helped me exceed
was sold in 2007, he started a new chapter with ZO Skin Health. In my potential. She runs the business side of Obagi Skin Health
keeping with his original vision, ZO markets products exclusively to Institutes, and oversees public relations and marketing, among
medical professionals in more than 100 countries. In fact, the company other ventures. I don’t know how she does it all.
is not afraid to target any business or individual that violates their strict
anti-diversion policy. A high functioning integrated team has been What is the best advice you can offer practitioners today?
crucial to the success of ZO Skin Health, and under the direction of To not just accept the status quo. Challenge yourself, do your
CEO Jim Headley, the ZO Skin Health brand has flourished Dr Obagi own research, experimentation, and clinical studies. You are
serves as the ZO Skin Health, Inc. medical director, where he drives never too good or too old to learn something new.
the development of new products, protocols and treatments.
“I make sure that each new formulation delivers the level of results Wendy Lewis president of Wendy Lewis & Co, a global
aesthetic consultancy business. Lewis is an international
our physician partners have come to expect and that their patients
figure in the field of medical aesthetics, and is a frequent
want,” he says. 2014 was a significant year for Dr Obagi, with the presenter at international conferences. In 2008, she
launch of the second edition of his original best selling textbook, founded Beautyinthebag.com and serves as editor in chief.

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Surgeons
Under this title practitioners should obviously be
surgically trained and have completed specialist
training, and therefore be on the GMC specialist
register. Each individual is in no doubt as to whether
or not they fulfil this criterion. Within the individual
professions, we understand the significance of being
on the GMC register as a doctor, and take this to be
a mark of excellence, having achieved a certificate
of completion. If we are not surgically trained or
have not completed our training, however, should
we be calling ourselves a plastic surgeon, aesthetic
surgeon or an ENT surgeon? To me, the answer is

The Last Word


a clear no – and I believe that only those who have
received their FRCS (Plast) status should be referred
to as plastic surgeons. The lay public may presume
that we have a level of expertise and seniority that
Dr Sam Robson argues for greater we have not actually earned. Is it really appropriate
clarity in the use of professional titles to allow a perception that we are more qualified than
we are? Should we be undertaking facial cosmetic
surgery procedures if our expertise is in orthopaedics
What’s in a name? Does it matter what we call ourselves when it comes to our – unless, of course, we have formal qualifications,
patients? I think it does. Aesthetic medicine can provide an important medical service experience and certification in these areas?
to patients, having a positive impact on their self-esteem and quality of life. Our job title
will convey a certain sense of experience, expertise and ability to both prospective Doctors
and current patients. The field is already considered to be a slightly grey area ethically. Are we General Practitioners (GPs) or General
As it comprises completely private medicine, it could be considered by some to be Practitioners with Special Interest (GPwSI)? Should
exploiting patients’ desperation for remedies to treat their aesthetic concerns, or even we use the term dermatologist if we do not have a
perhaps of selling ‘snake oil’ – a term used to describe fraudulent health products certificate of completion of training in dermatology?
or, more likely in our case, unproven medicine. To improve this negative association, Although cosmetic dermatology is recognised as
practitioners should strive to put patient care above financial gain. a sub specialty within dermatology,1 as far as I am
To this end, it is imperative that practitioners portray their capabilities and qualifications aware there is no real qualification of ‘cosmetic
honestly to the public and their patients. In 2015, the Care Quality Commission dermatologist’ and yet so many doctors with
(CQC) published an update to its Regulation of Candour which stated that, ‘Providers no formal qualification in dermatology claim this
[of healthcare] must promote a culture that encourages candour, openness and title. Would it not be more transparent to declare
honesty at all levels. This should be an integral part of a culture of safety that supports ourselves as GPs with an interest and some expertise
organisational and personal learning.’ Surely we should be advocating this culture in in cosmetic dermatology? (Although bear in mind the
our medical aesthetic clinics and complying with the CQC’s notion of openness and scope of this is yet to be defined.)1
honesty? Across the board, however, individuals claim to be “advanced” practitioners
and yet where is the evidence from their practice? To my mind, at every step of our Dentists
interaction with patients we must be open and credible in how we present ourselves. Unless a dentist has a medical qualification too, should
Simply put, we should first declare whether we are surgeons, doctors, dentists or they be calling themselves a ‘doctor’? It would appear
nurses and stand behind the recommendations that only practitioners with the that many dentists still call themselves ‘doctor’, despite
appropriate qualifications be permitted to perform aesthetic treatments. We should patients being confused by this and even expressing
then be clear on our individual claims within each of these four practitioner categories. in blogs a desire to have some clarity.2,3 In 2010, the
I have some concerns, however, about how individual practitioners prefer to portray General Dental Council (GDC) published a report on
themselves: patient and public attitudes to standards for dental
professionals.4 It stated that, “The current GDC proposal
is that the use of the term ‘doctor’ (or the abbreviation
Surely it is a fundamental Dr) by dentists should be limited to practitioners
who have a PhD or who are medically qualified and
expectation to be honest registered doctors. The document continued, “It is
against the law, for a dentist or DCP to use any title or
from the outset about who we description ‘reasonably calculated’ to suggest that (s)he
has a professional status or qualification other than one
actually are and our true level of which is indicated against his/her name in the register;
however, cases alleging misuse of titles, descriptions
qualifications and expertise or qualifications by dentists or DCPs can be dealt
with through GDC fitness to practise investigatory/
disciplinary processes.” The document further stated

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


aestheticsjournal.com @aestheticsgroup Aesthetics Journal Aesthetics

that, ‘Dentists and practices should not advertise themselves as of expertise, qualification or experience – without bamboozling the
specialists where no such specialist list exists.’5 Despite these points, layman with a cacophony of terms designed to impress as well. Is it
it seems many dentists continue to use the term ‘doctor’, which, in my not a fundamental expectation to be honest from the outset about
opinion, has the potential to confuse and mislead patients. who we actually are and our true level of qualifications and expertise,
before we subject a potentially vulnerable patient to aesthetic
Nurses treatment? We should be aiming to reassure the public that not only
There seems to be many varieties of nurses practising aesthetics; are we transparent about our ability and level of expertise; we are
my understanding is that there are aesthetic nurses, independent also aware of our limitations and will ultimately put the care of our
nurse prescribers, nurse practitioners, advanced nurse practitioners patients first. I believe that the job titles that we claim for ourselves
(ANPs) and aesthetic nurse specialists. There are nurses who are the first step in establishing ourselves as a credible and
call themselves ‘medical directors’, which, to me, suggests they trustworthy body of professionals.
are portraying themselves as doctors. Apart from independent
Dr Sam Robson trained as a GP before beginning her
nurse prescribers and ANPs, none of these titles require different career in aesthetics in 2004. She is the medical director of
or additional qualifications to one another and are merely self- Temple Medical in Aberdeen, an appraiser for the British
appointed titles. Nurse prescribers are an exception as they do College of Aesthetic Medicine and a voluntary medical
require a prescribing qualification, however, this does not indicate advisor for the Royal National Lifeboat Institution.
that a nurse is aesthetically trained – just that he or she has REFERENCES
completed a prescribing course.6 In 2007, the Nursing and Midwifery 1. Care Quality Commission, Regulation 20: Duty of Candour, (UK: Care Quality Commission, 2015)
<http://www.cqc.org.uk/sites/default/files/20150327_duty_of_candour_guidance_final.pdf>
Council (NMC) explained that the plethora of titles used by nurses 2. Yusef I et al, A career in dermatology (UK: British Medical Journal, 2010) <http://careers.bmj.com/
is of concern, as they do not help the public understand the level of careers/advice/view-article.html?id=20001048>
3. Hareyan A, Dentists are not doctors: It’s official now (UK, EmaxHealth, 2008) <http://www.
care that they can expect. In addition, the Royal College of Nurses emaxhealth.com/1/79/25802/dentists-are-not-doctors-it-039-s-official-now.html>
stated in 2012 that, “Both the RCN and NMC oppose nurses and/or 4. Jackson L, Surgeon, Doctor, Dentist – are they really who they say they are? (UK, Consulting
Room, 2012) <http://www.consultingroom.com/blog/309/surgeon,-doctor,-dentist---are-they-
employers using the title of ANP where a nurse has not completed really-who-they-say-they-are?>
the appropriate education and preparation.”7 Surely, we should be 5. http://www.gdc-uk.org/Newsandpublications/research/Documents/GDC%20Public%20
Attitudes%20to%20Standards%20for%20Dental%20Professionals.pdf
using one title for all aesthetic nurses or setting levels of qualification 6. Information available via the British Association of Cosmetic Nurse
where their title will change upon completion? It is confusing 7. Advanced nurse practitioners (UK: Royal College of Nursing, 2012) <https://www.rcn.org.uk/__data/
assets/pdf_file/0003/146478/003207.pdf>
enough for those of us within the profession to decipher any level

Annual British College


of Aesthetic
Medicine Conference
Registration for the annual
BCAM conference is now open!

This year’s event will be held at the Church House Conference Centre
on Saturday 26th September 2015
BCAM is the responsible body for aesthetic medicine and manages appraisals for aesthetic doctors. BCAM is
essential for you as an aesthetic doctor and so the annual conference on 26th September is not to be missed –
be there to ensure you don’t get left behind!
This year’s rich lineup includes speakers from the cutting edge of aesthetic medicine including Mr Rajiv Grover,
Dr Nick Lowe, Mr Paul Banwell, and Dr Ravi Jain.
Our conferences are always educational, informative and inspiring; an event where you can acquire new knowledge
and expand your development whilst networking with colleagues.
Register via the events page on our brand new website www.bcam.ac.uk/membership/events
NETWORKING SESSIONS WITH YOUR COLLEAGUES
FUN CHAMPAGNE RECEPTION BOOK YOUR PLACE TODAY

Reproduced from Aesthetics | Volume 2/Issue 8 - July 2015


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a d l
Dermagenica MedivaPharma
ABC Laser Contact: Greg Laser Physics 01908 617328
Contact: Guy Gouldsmit Info@dermagenica.co.uk +44 01829773155 info@medivapharma.co.uk
+44 08451 707 788 Www.dermagenica.co.uk info@laserphysics.co.uk www.medivapharma.co.uk
info@abclasers.co.uk 020 3515 0105 www.laserphysics.co.uk Service: Facial Aesthetic Supplies
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Merz Aesthetics
AestheticSource DermaLUX Lawrence Grant +44 0333 200 4140
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+44 01234 313 130 +44 0845 689 1789 +44 0208 861 7575
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Eden Aesthetics Lifestyle Aesthetics
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Service: exclusive UK distributor for the Lumenis UK Ltd Contact: Vernon Otto
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Flawless Aesthetics and Beauty

Mark Stevens www.neocosmedixeurope.co.uk
Flawless Aesthetics & Beauty
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Bausch + Lomb UK Ltd thecosmeticnurse@mail.com
thecosmeticnurse@mail.com

www.lumenis.com
Tel: 01400 281902

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tracey@blowmedia.co.uk
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Contact: Faye Price
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Division sales@medfx.co.uk Silhouette Soft
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BTL Aesthetics info.uk@galderma.com Contact: Emma Rothery
Lex Myatt www.galderma-alliance.co.uk www.silhouette-soft.com
01782 579 060 silhouettetraining@sinclairpharma.com
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h Hamilton Fraser
Contact: Stephen Law Medical Aesthetic Group
0800 63 43 881 Contact: David Gower
info@cosmetic-insurance.com +44 02380 676733
www.cosmetic-insurance.com info@magroup.co.uk Sinclair Pharmaceuticals
Candela UK Ltd www.magroup.co.uk info@sinclairpharma.com
Contact: Michaela Barker 0207 467 6920
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Carleton Medical Ltd Medico Beauty
Contact: Nick Fitrzyk John Bannon - Contact Name: Andy Millward Zanco Models
+44 01633 838 081 Pharma and Reconstructive Division. +44 (0) 844 855 2499 Contact: Ricky Zanco
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70 Aesthetics | July 2015


EMERVEL – MORE CHOICE AND
CONFIDENCE IN MID-FACE
FILLER SOLUTIONS
Volume is key to maintain facial balance and restore the faces natural contours. Emervel has gel textures
especially designed for lifting capacity and volume restoration, optimised especially for the mid-face regions.

EMERVEL DEEP FOR SHAPE EMERVEL VOLUME FOR VOLUME


REDEFINITION RESTORATION
Emervel Deep for patients who require mid-face Emervel Volume for patients who require mid-
shape redefinition due to flat zygomatic bones or face volume restoration due to volume loss
mild-to-moderate facial asymmetry. caused by ageing.

INTRODUCING EMERVEL VOLUME 1ML

SMOOTHER FLOW
• Optimized gel texture: Homogenous gel
particle calibration enables smooth and regular
extrusion

• 27 G Ultra-thin-wall needles improve flow rate


and reduce extrusion force

GREATER WORKING COMFORT


• Lightweight, ergonomic syringe for more
comfortable handling

• Lower extrusion force for reduced fatigue

OPTIMISED CHOICE
• Emervel Volume available in 1ml or 2ml - Your
choice of comfort and flexibility depending on
your patients’ needs.

You can sign up to receive email


& text message alerts through
Galderma (UK) Ltd Galderma (UK) Ltd’s A&C
Meridien House, 69-71 Clarendon Road, subscription service for Healthcare
Watford, Hertfordshire WD17 1DS Professionals and Non-Medical
Tel: 01923 208950 Email: info.uk@galderma.com Aesthetic Clinic Staff.  Scan here,
For more information visit www.galderma-alliance.co.uk or visit www.galderma-mail.co.uk

EME/030/0714 Date of prep: July 2014


Experience all the benefits of VYCROSS™ technology.
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Instructions and directions for use are available on request.

Allergan, Marlow International, 1st Floor, The Parkway Marlow, Buckinghamshire SL7 1YL, UK
Date of Preparation: August 2014 UK/0880/2014

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