when the active site of an eznyme are change in shape the substrate are no longer

bind the active site of the enzyme

QUICK MEANING OF DENATURING ENZYME:

WHEN THE ACTIVE SITE OF AN ENZYME CHANGE IN SHAPE, WE CALL THIS DENATURING, WHEN AN
ENZYME DENATURES THE SUBSTRATE CAN NO LONGER BIND THE ACTIVE SITE OF THE ENZYME,
CAUSING LESS PRODUCTS TO BE FORMED

EFFECT OF TEMPERATURE ON ENZYME ACTIVITY:

THE *OPTIMUM TEMPERATURE WHERE THE ENZYME'S RATE OF REACTION IS AT IT'S *HIGHEST.
IF YOU INCREASE THE TEMPERATURE ABOVE THE *OPTIMUM TEMPERATURE THE ENZYME'S ACTIVE
SITE WILL *DENATURE. THIS MEANS THE ENZYMES *ACTIVE SITE CHANGES *SHAPE. THE
SUBSTRATE CAN NO LONGER BIND THE *ACTIVE SITE OF THE DENATURED ENZYME SO THE RATE
OF REACTION DECREASES

IF YOU DECREASE THE TEMPERATURE BELOW THE OPTIMUM *TEMPERATURE, THE ENZYMES ACTIVE
SITE DOESN'T *DENATURE, BUT THE *KINETIC ENERGY STORED IN THE ENZYME AND SUBSTRATE
DECREASES. THIS MEANS THEY ARE MOVING *SLOWLY, SO THERE ARE FEWER *COLLISIONS
BETWEEN THE ENZYME AND *SUBSTRATE, THEREFORE THERE IS LESS *PRODCUT BEING FORMED,
AS THE *RATE OF REACTION DECREASES.

EFFECT OF PH ON ENZYME ACTIVITY:

TO BREAK DOWN A SUBSTRATE INTO *PRODUCTS, THE SUBSTRATE MUST BIND THE ACTIVE SITE
OF THE ENZYME. THE *ACTIVE SITE OF THE ENZYME AND THE SUBSTRATE ARE SPECIFIC TO ONE
ANOTHER, SO ONLY ONE SUBSTRATE CAN BIND ONE ENZYME. THE ENZYME WILL THEN BREAL THE
SUBSTRATE DOWN INTO PRODUCTS

THE *OPTIMUM PH IS THE PH WHERE THE ENZYMES RATE OF REACTION IS AT ITS *HIGHEST. IF
YOU INCREASE THE PH ABOVE OR BELOW THE *OPTIMUM PH THE ENZYME ACTIVE SITE WILL
*DENATURE. THIS MEANS THE ENZYMES *ACTIVE SITE CHANGES *SHAPE. THE SUBSTRATE CAN NO
LONGER BIND THE *ACTIVE SITE OF THE DENATURED ENZYME, SO THE RATE OF REACTION
DECREASES