Professional Documents
Culture Documents
Nikita Goyal
29, Gyan Khand 1, Indirapuram,
Ghaziabad. India
+91-98964-92776
Email: nikitagoyal29@gmail.com
Research Experience
2017-2020 Research project as Senior Research Fellow “Studies on mechanism of Action and
Development of radio- mitigation from HDAC Inhibitor”
➢ The effect of radiation on lymphocyte cells and HEK cell line and the study
of different DNA anomalies
➢ Effect of radiation on Different Physiological system (C57BL/6mice) and their modification by HDAC
inhibitors
➢ To investigate In vivo and In vitro study of effect of HDACi in radiation induces Double Stranded
Break Repair.
➢ To study of effect High LET and its mitigation using HDACi.
➢ Isolation and screening of different of oil degrading bacteria from the soil samples collected from
different oil fields.
➢ Monitoring of isolated bacteria on synthetic media to check their oil degrading capacity.
➢ Sequence analysis of bacteria’s which will show maximum degrading capacity.
2015-2016 Master’s Dissertation Project “Functional profiling of Genetic Variants of Beta Casein
(βCN) Across Indian Native, Exotic and Crossbred Cattle Population”
➢ To sequence characterize and identify different allelic variants of Beta-Casein in Indian native, exotic
and crossbred populations.
➢ To generate corresponding haplotype and estimate extent of linkage disequilibrium across
identified variants of Beta-Casein gene.
➢ To ascertain the expression profile of different Beta-Casein allelic variants in cow mil epithelial
cells.
➢ To delineate Beta-Casein peptide variants corresponding to major allelic variants/haplotype in cow milk
using LC/MS.
Technical Skills
➢ Molecular Biological / Immunological techniques expertise: Protein, RNA and DNA isolation.,
Agarose gel electrophoresis, Sanger Sequencing, RT-PCR (semi-quantitative), Real Time PCR
(quantitative), Western Blotting, PAGE (native & SDS), Immunohistochemistry (IHC),
Immunofluorescence, Flow Cytometry, Microscopy (Fluorescence, Bright Field).
➢ Animal cell culture: Experience in working with PBMC’s and HEK cell line.
➢ Bioinformatics: Primer designing using Primer3 and NCBI/Primer-BLAST. BLAST analysis of
sequences, Multiple sequence alignment, Codon Code Aligner.
➢ Microbiological: Isolation, Screening, Preservation & Identification of micro-organism from different
Samples- soil, water and food products.
➢ Experience in working with small laboratory animal (C57BL/6 mice).
Publications
➢ 5 Sequences of Karan Fries (Indian Cross Bred Cattle Cow) Beta-Casein gene have been submitted at
NCBI
➢ Abstract Published at International conference of Radiation Biology held at Mangalore 4-6th October
2018.” In vitro Evaluation of EGCG as a Potential Radiomitigator”. Nikita Goyal1, Mrinalini Tiwari1, and
Paban K Agrawala1*
➢ Abstract Published at International Conference of Radiological emergency and Management
ICONRADEM 2019, Jiapur 9-11 Feb 2019,” Radio mitigative Effect of EGCG, Major Polyphenol of Green
Tea Extract”. Nikita Goyal1, Mrinalini Tiwari1, and Paban K Agrawala1*
Awards/Fellowship
Educational qualification
References
1. Dr.P.K. Agarwala Scientist E, INMAS, Defense Research and development Organization (DRDO),
New Delhi – India.
Email: paban@inmas.drdo.in
Tel: +91-9416435184
2. Dr. Monika Sodhi, Principal Scientist Animal Biotechnology, National Bureau of Animal Genetics
Resources (NBAGR), India.
Email: monikasodhi@yahoo.com
Tel: +91-9729591871
3. Dr. Manishi Mukesh, Principal Scientist, National Bureau of Animal Genetics Resources
(NBAGR), India.
Email: mmukesh_26@hotmail.com
Tel: +91-184-2267153, 91-9896043048
Declaration
I hereby declare that all the information given above is appropriate at best of my knowledge.
Nikita Goyal