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(g) the ethical issues (both positive and negative) To include insect resistance in genetically modified

relating to the genetic manipulation of animals soya, genetically modified pathogens for research
(including humans), plants and microorganisms and ‘pharming’ i.e. genetically modified animals to
produce pharmaceuticals
AND
issues relating to patenting and technology transfer
e.g. making genetically modified seed available to
poor farmers.

2 HSW10
(h) the principles of, and potential for, gene therapy To include the differences between somatic cell gene
in medicine. therapy and germ line cell gene therapy.

HSW9, HSW12

6.2 Cloning and biotechnology

6.2.1 Cloning and biotechnology

Farmers and growers exploit “natural” vegetative Biotechnology is the industrial use of living organisms
propagation in the production of uniform crops. (or parts of living organisms) to produce food, drugs or
Artificial clones of plants and animals can now be other product.
produced.

Learning outcomes Additional guidance


Learners should be able to demonstrate and
apply their knowledge and understanding of:
(a) (i) n
 atural clones in plants and the production To include examples of natural cloning and the
of natural clones for use in horticulture methods used to produce clones (various forms of
(ii) h
 ow to take plant cuttings as an example of vegetative propagation).
a simple cloning technique
Dissection of a selection of plant material to
produce cuttings.

PAG2
HSW4
(b) (i) t he production of artificial clones of plants To include an evaluation of the uses of plant cloning
by micropropagation and tissue culture in horticulture and agriculture.
(ii) t he arguments for and against artificial
HSW9, HSW12
cloning in plants
(c) natural clones in animal species To include examples of natural clones (twins formed
by embryo splitting).
(d) (i) h
 ow artificial clones in animals can be To include an evaluation of the uses of animal
produced by artificial embryo twinning or cloning (examples including in agriculture and
by enucleation and somatic cell nuclear medicine, and issues of longevity of cloned animals).
transfer (SCNT)
HSW9, HSW10, HSW12
(ii) t he arguments for and against artificial
cloning in animals

© OCR 2016
46 A Level in Biology A

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