CLINDAMYCIN (Cleocin)

-antibiotics, Lincosamide

Patient’s Dose: 150 mg/ml IVTT

Pt.’s Indications: Prophylaxis (surgical infection)

Pregnancy Category: B

Contraindication: Hypersensitivity to Clindamycin or Tartrazinedye

Ulceritive Colitis

Regional Enteritis

Pseudomembranous Colitis

Onset: Immediate

Peak: Immediate

Duration: Unknown

Mechanism of Action: suppresses protein synthesis by binding to 50s ribosomal units

Adverse Reaction(s):

CV: thrombophleblitis

GI: Nausea, Pseudomembranous colitis, abdominal pain, diarrhea

Hematologic: thrombocytopenia, transient leucopenia

Hepatic: Jaundice

Skin: maculopapular rash, urticaria

Other: Anaphylaxis

Nursing Responsibilities:

Before:

 Check doctor’s order.

 Assess patient’s infection.
 Obtain specimen for culture and sensitivity test.
 Monitor renal, hepatic and hematopoetic functions.

During:
  Be alert for adverse reactions
 Provide patient’s safety
 If adverse GI reaction occurs, monitor hydration status

After:

 Instruct patient to report diarrhea and to avoid self-treatment because of the risk of life-
threatening pseudomembranous colitis
 Tell patient to report discomfort at IV site.
 Document in medication sheet.