T.Y. B.Pharm.

Sem VI AY: 2020-21

Basic Principles of Toxicology CBCS
Online mode examination
Blue Print End Semester Exam 2021

No. of
Level of No. of No. of No. of
Question questions
Question No. the questions questions questions
Pattern from Unit
question from Unit 1 from Unit 2 from Unit 3
4
Easy 5 5 5 5
Q.1 MCQ 20 M Medium 3 3 3 3
Difficult 2 2 2 2
Descriptive 2 2 2 2
Q.2 Difficult
4 M
Descriptive Moderate 2 2 2 2
Q.3
16 M Easy 3 3 3 3

This blue print is made in accordance to the online End Semester Exam 2021 exam system
prescribed by University of Mumbai. The no. of questions mentioned against each unit
represents the no. of questions for four sets of question papers.
 SYLLABUS

No of
Unit
Unit details hours Topic details
No
alloted
Factors
influencing
1 General toxicity, Definitions: Toxicology,
Introduction Management of Mechanisms of Poisons, Hazards, Risk
to toxicology 5 poisoning toxicity Classification of toxicity
Introduction to the terms
with suitable examples of
drugs and its clinical
repercussions:
genotoxicity,
carcinogenicity,
teratogenicity,
2
Clinical mutagenicity,
symptoms and hepatotoxicity,
management of nephrotoxicity,
alcohol, cardiotoxicity,
Drug barbiturate and Examples of neurotoxicity,
induced morphine drugs causing haematotoxicity and local
toxicities 6 poisoning. these toxicities toxicity
Types of Brief
toxicological introduction to
testing: Acute, alternatives to Types of toxicological
3
Sub acute and Animal Models testing: Acute, Sub acute
Toxicity Chronic toxicity for toxicological and Chronic toxicity
testing 5 studies testing studies
Overview of
regulatory laws
and agencies: Risk assessment
4 Local Drug and
Regulatory management of Schedule Y: Design of non-
Regulatory Agencies, OECD toxicological clinical toxicity studies and
toxicology 8 and ICH risks clinical development
Total 24