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Acknowledgement of Country
We respectfully acknowledge the Indigenous Elders, custodians, their descendants and kin of this land past and
present. The Centre for Aboriginal Studies aspires to contribute to positive social change for Indigenous
Australians through higher education and research.
Syllabus
This unit covers both theoretical and practical aspects of biochemistry. Structure and properties of water.
Concepts of pH, pK and buffers. Molecular structure and chemical bonds. Properties, structures and functions of
amino acids, lipids, carbohydrates and nucleic acids. Structure and function of globular and fibrous proteins.
Concepts and properties of enzymes including enzyme kinetics. Overview and concepts of biological
thermodynamics, energy metabolism and metabolic pathways. Intermediary metabolism including metabolic
pathways of glycolysis, citric acid cycle, pentose phosphate pathway, gluconeogenesis, amino acid metabolism,
fatty acid metabolism, ketone body metabolism, oxidative phosphorylation and electron transport. Molecular
visualisation of proteins. Practical skills and techniques. Using scientific instruments and analysing scientific data.
Introduction
Welcome to Foundations of Biochemistry!
Biochemistry is "the study of chemical and physico-chemical processes within and related to living
organisms". Therefore, we are considering how life works at the molecular level! Biochemistry is an important
subject because it is also the basis of most other health science subjects. This unit is designed to expand your
knowledge, develop your skills, and provide you with the foundations of biochemistry.
Your achievement of the learning outcomes in this unit will depend upon your motivated and diligent efforts
to keep pace with the material; your ability to study your lectures, text, and other relevant materials; actively
participate in all lectures and practical classes; and take the opportunity to ask questions and learn. In fact,
t he guiding philosophy of this unit is that you learn by asking questions!
Please take the time to read this unit outline carefully and thoroughly. It explains most of what you need to
know about the design of Foundations of Biochemistry and what will be expected of you in this unit. We
hope you will find this unit enjoyable, challenging, and rewarding.
All the best!
Dr Carl Mousley
Unit Coordinator & Lecturer for Foundations of Biochemistry
First things you need to do!
Graduate Capabilities
On successful completion of this unit students can:
addressed
1 Demonstrate knowledge and understanding of key facts and concepts of
biochemistry
2 Apply new and existing knowledge to solve problems in biochemistry
Find out more about Curtin's Graduate Capabilities at the Curtin Learning and Teaching website: clt.curtin.edu.au
Learning Activities
The principal learning activities in this unit are lectures, practical classes, practical reports, topic quizzes, and
'Questions for Learning'.
Lecture topics
The lectures are where you learn and build your knowledge of biochemistry. This unit uses a straightforward,
and innovative, way for you to study and learn biochemistry. Essentially, the lecture syllabus is divided into
24 topics and you should study each topic using the WRQ system. The WRQ system essentially contains a
three-step process: watching (W), reading (R), and questioning (Q). The details are as follows:
W – Watch
l Watch the ilecture, the prerecorded lecture, or attend the live lecture class. If you watch the ilecture, or
prerecorded lecture, then you can watch in one sitting, pause along the way, or select the particular
parts of the lecture you want to review. In any case you should actively watch the lecture. This means
that you should try to ask yourself questions and write notes.
l If you decide to attend the lecture class and watch the ilecture again later, then you obviously must
expect to spend more time at this step.
l A lecture is usually scheduled from about 30 to 45 minutes with any remaining time available for
students (who attend a lecture class) to ask questions and receive feedback.
l Read the text, the printed lecture, or other recommended resources for more detail or to gain another
perspective.
l Review and summarise what you read.
l Read to answer any questions you asked yourself whilst watching the lecture or during your review.
Important
l Lectures give you an opportunity to ask questions and discuss the subject with your fellow students.
One of the principal teaching and learning ideas in this unit is that you learn by asking questions! Ask
yourself questions, ask your fellow students, and ask your lecturer.
l The content of any lecture may be modified, or updated, at the ‘last minute’. These ‘last minute’
changes are certainly not an indication of disorganisation. You should understand that these changes
are usually designed to present recent material, aid student learning, adjust to the perceived progress
of the student cohort, or the result of feedback from students. They are for the benefit of students and
not meant to be inconvenient or to confuse. These changes are at the discretion of the lecturer.
l Do not expect a lecture to always be a ‘one-way’ learning experience (lecturer to you) where you can
‘sit back and relax’ or be ‘entertained’. You will be expected to think and contribute during the lecture.
l Be prepared for lectures (live or prerecorded)! Read the lecture notes, textbook chapters, and any
other reading before attending lectures.
l Lectures should be viewed as your study guide to each topic.
l Your attention in the lecture is important for your learning. Any unnecessary, disruptive, or unrelated
activity by students during lectures may result in the embarrassment of the student(s) being asked to
leave the lecture.
l If lecture notes are unavailable for any reason (or even if they are available) you are still responsible for
making your own notes during or after the lecture!
l Your understanding of each topic will only be achieved by broader reading of your text and other
reference materials. Lectures alone will usually not suffice.
l Remember, it is your understanding of the topics that will be assessed in this unit!
Practical Classes
The practical classes are where you develop your practical knowledge and practical skills.The practical syllabus
is covered by a series of nine practical classes throughout the semester and the content in the 'Biochemistry
Laboratory Techniques Study Guide'.
l The practical syllabus is different from the lecture syllabus although there may be some 'cross over',
similarity, or complementarity to some lecture topics. You should not expect practical topics to be the
same as the lecture topics and vice versa.
l The background knowledge for the practical skills is found in the 'Laboratory Techniques Study Guide'.
You should carefully read the appropriate chapters in the study guide before each practical class.
l Details of each particular practical class, and the skills performed in each class, are found in the
Practical Skill Notes.
l The Laboratory Techniques Study Guide and the Practical Skill Notes can be viewed on, or downloaded
from, Blackboard.
eTests
Online laboratory tests
The online laboratory tests are where you learn, practice, question, and develop your knowledge of practical
skills. These are designed to consolidate your knowledge, and provide further knowledge, of the practical
activities conducted in the practical class. There is a laboratory test for each corresponding practical class.
Further details on the practical report is given in the explanation of assessments.
Online theory tests
The online theory tests are where you learn, practice, question, and develop your knowledge of biochemistry.
These are an important part of the WRQ learning method. For each lecture topic there is an online test and
these tests are designed to help guide your learning of biochemistry. In particular they help you determine:
They are also a useful for revision aid, and practice questions, for the end of semester exam. All online theory
tests will close on the morning of the scheduled review exam at the end of semester.
Questions for Learning
You will find questions labelled 'Questions for Learning' in practical classes and lectures. These questions are
designed to further your knowledge and help you integrate some topics.
Study Load
The following are the suggested study times for the learning activities in this unit:
l Contact time consists of 2 x 1hr lectures and 1 x 3hr practical class. A total of 5 hours contact time
that is also your study and learning time.
l WRQ study method: About 2 hours per week. This is your study and reading time.
l Topic Quizzes: About 2 hours per week for two topic quizzes. This is also your study and learning time.
l Practical Reports: About 1 hour per week. Reports have a duration of about 2 weeks, so this is
equivalent to about 2 hours per practical report.
The total hours required to study, and learn, the contents of this unit are about 10 hours per week. However,
the time you spend studying for this unit depends upon your academic background, your ability to study,
your motivation, and your ability to organise yourself. In any case, you can see how this unit is carefully
designed with activities that can help you study and learn.
Feedback
Feedback is an important, and integral, part of this unit and occurs in two basic forms:
l When verbal or written information is exchanged directly between you and your lecturer or between
you and your laboratory supervisor.
l When you receive written answers or explanations from a quiz, a practical report, lectures, practical skill
activity, tutorial, or test.
Feedback can occur at any time during semester either in class or out of class. Additional feedback ‘out of
class’ can occur through Curtin’s Blackboard learning management system (e.g. Announcements and the
Bulletin Board) or by any other form of acceptable communication (e.g. email or personal appointment).
Please understand that feedback is necessarily a two-way process. Feedback involves you providing
information to help the lecturer, or laboratory supervisor, learn more about you, your knowledge, or correct
any misunderstanding. Your lecturer, or laboratory supervisors, provide you information to help you learn,
Learning Resources
Recommended texts
You do not have to purchase the following textbooks but you may like to refer to them.
l Learning resources include a textbook, useful web sites, and various learning aids as described below.
Textbook
Jeremy M. Berg, Lubert Stryer, John Tymoczko, Gregory Gatto. Biochemistry (9th Edition)
Author(s): Jeremy M. Berg, Lubert Stryer, John Tymoczko, Gregory Gatto
An earlier or later edition of the textbook would also be acceptable.
(ISBN/ISSN: 9781319114671)
l Learning resources include a textbook, useful web sites, and various learning aids as described below.
Textbook
Ferrier, D.R., (2017) Lippincott's Illustrated Reviews: Biochemistry. 7th Edition. Lippincott Williams &
Wilkins.
An earlier or later edition of the textbook would also be acceptable. However, you should understand
that the lecture notes may refer mainly to the 7th Edition of the textbook. Electronic versions are also
available online from the publisher and possibly other vendors.
(ISBN/ISSN: 9781496344496)
Other resources
You will need access to Curtin University’s internet learning management system (lsm) called Blackboard. You
should be able to effectively explore the Internet where there is a wealth of freely available information. You
may also be referred to some web sites, or additional software, during the course of your study. When you
use the internet you must ensure that the source of information comes from a reputable, qualified, and
professional institution or person.
Useful web sites
l Foundations of Biochemistry Blackboard site. This can be accessed from your Oasis account or directly
from your browser using the URL: http://lms.curtin.edu.au
l Curtin University library have various guides for study and research skills see:
http://library.curtin.edu.au/
l Textbook web site. If you use the recommended textbook, then each text has a code on the inside of
the front cover to access the text book’s web site. The web site contains study aids that you may like
to use to supplement your learning.
Learning aids
The learning aids for this unit are extensive and include:
You should make use of as many of these resources as possible to guide, complement, and enhance your
own learning.
Assessment
Assessment schedule
Unit
Late Assessment
Value Learning
Task Date Due Assessments Extensions
% Outcome(s)
Accepted?* Considered?*
Assessed
eTest 25% Week: Every 1,2,3,4 Yes Yes
teaching week from
week 1.
Day: Due date
indicated for each
1 report on
Blackboard
Time: Due time
indicated for each
report on
Blackboard
Practical Exam 35% Week: Week 14 1,2,3,4 Yes Yes
Day: Day of usual
2 practical class
Time: Time of usual
practical class
Theory Exam 40% Week: Examination 1,2 Yes Yes
Week
Day: Centrally
Scheduled as
advised through
3
Oasis
Time: Centrally
Scheduled as
advised through
Oasis
*Please refer to the Late Assessment and the Assessment Extension sections below for specific details and
conditions.
1. eTests
The online theory (topic) and laboratory (practical) tests are a continuing assessment that you must
complete throughout semester. These tests are completed using the Blackboard learning management
system. The theory tests are designed for you to learn, keep pace with the subject material, and be
rewarded you for your efforts. The laboratory tests relate to the content in practical classes and in the
'Biochemistry Techniques Laboratory Study Guide'. You should carefully read the Biochemistry
Techniques Laboratory Study Guide throughout the semester.
Theory tests
l The tests are available on Blackboard and you can take a test any time you like, wherever you
exam through Oasis.
l Some questions will involve calculations using an approved scientific calculator that you should
bring with you to the exam.
l The exam will be conducted during the last week of semester (week 14) at the same day, and
time, as your usual practical class. For example, if your usual practical class is Monday 1pm to
4pm in 310.103, then you will take your exam in this class. You will not be allowed to swap
classes to take the exam.
l The mark for the exam will be converted to a mark out of 35% for this component of the
assessment. For example, if you achieved a mark of 60/100 for the exam then this would equate
to 60/100 x 35 = 21% for this component of the assessment.
You are responsible for:
l Attending the exam at your usual practical class day and time.
l Learning all necessary content in preparation for the exam
l Being fully prepared for the exam including having your student ID available
3. Theory Examination
This exam reviews all of the syllabus of this unit but principally from lecture topics 1 to 23.
l This written end of semester review exam is a two-hour, supervised, exam. Most of the
questions will be similar to the questions you encounter in the topic quizzes. Consequently, it is
a good strategy for you to learn from all of the quizzes before this exam. Some questions may
also come from the practical syllabus.
l Some questions will involve calculations using an approved scientific calculator that you should
bring with you to the test.
l The exam will be conducted at a date and time to be determined during the two weeks reserved
by Curtin University for examinations at the end of semester. You will be advised on the due
date and time of the exam by an official communication via Oasis.
l The mark for the exam will be converted to a mark out of 40% for this component of the
assessment. For example, if you achieved a mark of 60/100 for the exam then this would equate
to 60/100 x 40 = 24% for this component of the assessment.
You are responsible for:
l Learning all necessary content in preparation for the exam.
l Attending the exam at the scheduled date and time.
l Being fully prepared for the exam including having your student ID available.
Pass requirements
You need to achieve an overall combined mark of at least 50% of the total semester mark to pass this unit.
You are also required to satisfactorily attempt all assessments in this unit. A satisfactory attempt means that
you complete at least 50% of each assessment. The Board of Examiners will make the final decision on your
status in the unit (i.e. pass, fail, or fail-incomplete). Consequently, it is important for you to demonstrate to
the Board that you are a diligent student, that you have attempted all components of assessment, and made
an appropriate effort in the unit.
Assessment Moderation
Pre-marking moderation
Staff responsible for assessing student work will, as a minimum, be provided with an assessment rubric (or marking
guide) in advance of the marking task. Assessment task details and marking criteria will be made available to students
when the assessment task is assigned or in the unit outline.
Intra-marking / Post-marking moderation
Intra-marking moderation
Intra-marking strategies may be implemented as deemed necessary following submission of assessment artefacts.
Post-marking moderation
Post-marking moderation will include (but is not limited to):
Late assessment
Where the submission of a late assessment is permitted, late penalties will be consistently applied in this unit.
Where a late assessment is permitted for an assessment item or the entirety of the unit (refer to the Assessment
Schedule table in this Unit Outline) and the student does not have an approved assessment extension:
1. For assessment items submitted within the first 24 hours after the due date/time, students will be penalised
by a deduction of 5% of the total marks allocated for the assessment task;
2. For each additional 24 hour period commenced an additional penalty of 10% of the total marks allocated
for the assessment item will be deducted; and
3. Assessment items submitted more than 168 hours late (7 calendar days) will receive a mark of zero.
Where late assessment is NOT permitted for an assessment item or the entirety of the unit (refer to the
Assessment Schedule table in this Unit Outline) and the student does not have an approved assessment extension:
1. All assessment items submitted after the due date/time will receive a mark of zero.
Assessment extension
Where an application for an assessment extension is permitted for an assessment item(s) within this unit (refer to
the Assessment Schedule table in this Unit Outline):
1. A student who is unable to complete an assessment item by/on the due date/time as a result of exceptional
circumstances beyond the student’s control, may apply for an assessment extension on the Assessment
Extension Application Form as prescribed by the Academic Registrar. The form is available on the Forms
page at https://students.curtin.edu.au/essentials/forms-documents/forms/ and also within the student’s
OASIS (My Studies tab – Quick Forms) account.
2. The student will be expected to submit their application for an Assessment Extension with supporting
documentation:
a. Australian Campuses: via the online form
b. Offshore campuses: to the School representative nominated below
3. Timely submission of this information supports the assessment process. For applications that are declined,
delayed submission may have significant ramifications on the possible marks awarded.
4. An application may be accepted up to five working days after the due date/time of the assessment item
where the student is able to provide a verifiable explanation as to why they were not able to submit the
application prior to the assessment due date/time
Where an application for an assessment extension is NOT permitted for an assessment item(s) within this unit
(refer to the Assessment Schedule table in this Unit Outline):
1. All assessment items submitted after the due date/time will be subject to late penalties or receive a mark of
zero depending on the unit permitting late assessment submissions.
Deferred assessments
If your results show that you have been granted a deferred assessment you should immediately check OASIS for
details.
Deferred examinations/tests will be held from 22/06/2020 to 17/07/2020 . Notification to students will be made
after the Board of Examiners’ meeting via the Official Communications Channel (OCC) in OASIS.
Further assessment
Further assessment is not available in this unit.
Referencing style
The referencing style for this unit is APA 6th Ed.
More information can be found on this style from the Library web site:
http://libguides.library.curtin.edu.au/referencing.
Privacy
As part of a learning or assessment activity, or class participation, your image or voice may be recorded or
transmitted by equipment and systems operated by Curtin University. Transmission may be to other venues on
campus or to others both in Australia and overseas.
Your image or voice may also be recorded by students on personal equipment for individual or group study or
assessment purposes. Such recordings may not be reproduced or uploaded to a publicly accessible web
environment. If you wish to make such recordings for study purposes as a courtesy you should always seek the
permission of those who are impacted by the recording.
Recording of classes or course materials may not be exchanged or distributed for commercial purposes, for
compensation, or for any other purpose other than personal study for the enrolled students in the unit. Breach of
this may subject a student to disciplinary action under Statute No 10 – Student Disciplinary Statute.
If you wish to discuss this please talk to your Unit Coordinator.
Copyright
The course material for this unit is provided to you for your own research and study only. It is subject to
copyright. It is a copyright infringement to make this material available on third party websites.
Additional information
Unsure what to do? Need help?
Are you unsure what to do, do not understand what is required of you, or need help? Do the following:
General Administrative Questions
l Please contact the Student Services Officers of your course. The contact details are in this unit outline.
l Carefully re-read the unit outline. If you still have questions, then please contact the unit coordinator.
You can contact him by email, telephone, or by meeting him in his office. His contact details are in this
unit outline.
l Please feel free to ask the lecturer questions during or immediately after a lecture. Sometimes
several students may ask questions after a lecture, so you may have to 'wait your turn' to ask your
questions. Don't be afraid to ask questions, but please make sure you do some thinking about your
question before asking. You may be asked questions to try and understand your question, to
understand your current knowledge, help correct any misunderstanding, and to be better placed to
respond to your question. If your question cannot be answered immediately the lecturer may ask to
get back to you at a later time, but they will get back to you!
l You can contact the lecturer by email, telephone, or by meeting in their office. The contact details of
the unit coordinator are in this unit outline. The unit coordinator will gladly receive your email at any
time or day. However, if you send your email late at night, early in the morning, during a weekend,
during a public holiday, during sick leave, or during annual leave, then please don't expect an
immediate reply. The unit coordinator will usually try and respond to your email as soon as possible.
Telephone enquiries and requests for a meeting are only accepted during normal office hours.
However, you can leave a message anytime when you make a telephone call. The unit coordinator has
an 'open-door' office and you may call in at any time during normal office hours. However, please
understand that the unit coordinator is busy and may not always be able to meet with you at short
notice. If this happens you may asked to arrange a meeting at another time or day that is convenient
for all.
l If you have a question about biochemistry you may post your question on the discussion board on
Blackboard.
l Ask your fellow students during your practical class.
l Ask your laboratory supervisors during your practical class. The laboratory supervisors may ask you
questions to try and understand your question, understand your current knowledge, and help correct
any misunderstanding.
l Please explore the services and amenities offered to students at the 'current students web page'
http://students.curtin.edu.au
Counselling Services
l If you feel overwhelmed, depressed, or 'can't cope', then you may like to consider personal counselling.
The Counselling Services at Curtin University are located in the centre of the Bentley campus at Level
2, Building 109. The following phone numbers are for office hours only Telephone: +61 8 9266 7850
or 1800 651 878 (Freecall).
Information on all of the above is available through the University's "Student Rights and Responsibilities" website
at: students.curtin.edu.au/rights.
Student Equity
There are a number of factors that might disadvantage some students from participating in their studies or
assessments to the best of their ability, under standard conditions. These factors may include a disability or
medical condition (e.g. mental illness, chronic illness, physical or sensory disability, learning disability), significant
caring responsibilities, pregnancy, religious practices, living in a remote location,or another reason. If you believe
you may be unfairly disadvantaged on these or other grounds please contact the appropriate service below. It is
important to note that the staff of the University may not be able to meet your needs if they are not informed of
your individual circumstances, so please get in touch with the appropriate service if you require assistance.
To discuss your needs in relation to:
To view previous student feedback about this unit, search for the Unit Summary Report at
https://evaluate.curtin.edu.au/student/unit_search.cfm. See
https://evaluate.curtin.edu.au/info/dates.cfm to find out when you can eVALUate this unit.
These developments occurred from consultations between staff members and between staff members and
students. Moreover, any changes implemented are aimed to enhance the student learning experience by
trying to make biochemistry easier to learn.
Program calendar
Week Begin Lecture 1 Lecture 2 Practical Classes
Date Biomedical Science:
(recorded) (recorded)
310.103AB
Monday: 9am-12 or 1-
4pm
Tuesday: 9am-12 or 1-
4pm
Wednesday 9am-12 or
2-5pm
7. 12 April 11.Fatty acids and Lipids 12. Nucleotides & Nucleic Practical 5
(C.M.) Acids (R.M.)
10. 3 May 17. TCA Cycle (A.C.) 18. Electron transport & Practical 7
Oxidative Phosphorylation
(C.M.)
12. 17 May 21. Lipid metabolism 22. Protein & Amino Acid Practical 9
(R.C.) Metabolism (R.C.)
13. 24 May 23. Fed & Fasting State Revision Practical exam
R.M. = Prof. Ricardo Mancera, C.M. = Dr. Carl Mousley, A.C. = Dr. Andrew Crowe & R.C. = Dr. Rima Caccetta