Precipitating Factors Predisposing Factors

- Diet - Age
- Lifestyle - Sex
- Smoking - Genetics

Present Illness of Diabetes Mellitus Type I

Poor management of blood sugar Hyperglycemia

Occlusion of the vasa nervorum

Loss of sensation
Peripheral Nerve Damage
Numbness

Injury
(traumatic injury / puncture)

Loss of skin integrity and

damage
to underlying tissue Port of entry

Inability to recognize presence of multiplication of

wound due to Diabetic neuropathy microorganism

Tissue Necrosis

- calor, dolor, palor,

Activation of immune response and tumor
- increased WBCs
- Fever

INFECTION