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Name of Drug Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibilities

Generic Name: As stated, carvedilol is > indicated for >contraindicated in >Body as a >Do not engage in hazardous
Carvedidol a non-selective the chronic therapy of patients with Whole: Increased activities while experiencing
adrenergic blocker, heart failure with bronchial asthma or sweating, fatigue, dizziness.
Brand Name: and more reduced ejection related chest pain, pain,
Coreg, Coreg CR specifically, is a non- fraction (HFrEF), bronchospastic arthralgia.
selective beta-blocker hypertension, and left conditions, >Do not abruptly discontinue
Classification: with alpha1-adrenergic ventricular decompensated >CV: Bradycardia, taking this drug.
Beta-blockers receptor antagonist dysfunction following NYHA functional hypotension, syncope,
properties. It is a non- myocardial infarction class IV heart failure hypertension, AV
selective, cardiac beta- (MI) in clinically stable requiring block, angina.
blocker with peripheral patients intravenous >Monitor for worsening of
vasodilating effects. inotropic therapy, >GI: Diarrhea, nausea, symptoms
Secondary to its unique severe liver abdominal pain,
action, carvedilol impairment, second- vomiting
maintains cardiac or third-degree
output by decreasing atrioventricular
afterload in block, sick sinus
conjunction with a syndrome (unless a
cardiac beta-blockade permanent
and has a lesser effect pacemaker is in
on heart rate than pure place), cardiogenic
selective beta-blockers. shock, severe
Other benefits include bradycardia or
antioxidant effects, known
reduction in neutrophil hypersensitivity to
infiltration, apoptosis the drug.
inhibition, reduction of
vascular smooth
muscle migration, and
improvement of
myocardial remodeling
post-acute myocardial
infarction. Because
carvedilol can prevent
the formation of
oxidized low-
density lipoproteins
and inhibit vascular
smooth muscle cell
proliferation and
migration, it shows a
great promise in
treating atherosclerotic
disease formation and
progression.
Name of Drugs Mechanism of Indications Contraindications Adverse Effect Nursing
Action Responsibilities
Generic Name: Terazosin dilates Mild to Moderate >Hypersensitivity >Monitor dizziness, >Monitor blood
Terazosin hcl both arteries and hypertension headache, pressure (lying and
veins by blocking (alone or with weakness, standing) and pule
Brand Name: postsynaptic alpha- other agents.) drowsiness, frequently during
Hytrin adrenergic Urinary outflow nervousness, and initial dose
receptors. obstruction in dyspnea. adjustment and
Classification: Decreases patients with periodically during
Alpha Blockers, contractions in prostatic therapy.
Antihypertensives smooth muscle of hyperplasia.
the prostatic >Assess patient for
capsule. >First dose first-dose
orthostatic orthostatic
hypotension, hypotension and
arrhythmias, chest syncope. May occur
pain, palpitation, 30 mins-2 hrs after
peripheral edema, initial dose and
tachycardia. occasionally
thereafter.
Incidence may be
dose related.
Volume-depleted
or sodium-
restricted patients
may be more
>Nausea vomiting sensitive to this
abdominal pain effect.
diarrhea, dry
mouth. >Monitor intake
and output ratios
and daily weight,
assess for edema
daily, especially at
beginning of
therapy.

Name of Drug Mechanism of Indications Contraindications Adverse Effect Nursing


Action Responsibilities
Generic Name: Blocks Telmisartan is >Hypersensitivity >Hypotension, >Assess blood
Telmisartan vasoconstrictor and indicated for the (e.g. anaphylaxis or dizziness, fatigue, pressure (lying
aldosterone treatment of angioedema) headache down, sitting,
Brand Name: producing effects hypertension, to standing) and pulse
Micardis of angiotensin II at lower blood periodically during
receptor sites, pressure. Lowering therapy.
Classification: including vascular blood pressure >Drug induced
Angiotensin II smooth muscle and reduces the risk of hepatitis, diarrhea. >Monitor
receptor the adrenal glands. fatal and nonfatal frequency of
antagonist, cardiovascular prescription refills
antihypertensives events, primarily to determine
strokes and adherence.
myocardial
infarctions.
Name of Drug Mechanism of Indications Contraindications Adverse Effect Nursing
Action Responsibilities
Generic Name: Etoricoxib works by >Arcoxia is >Arcoxia is >feeling sick > Instruct patient to
Etoricoxib blocking the effect indicated for: Acute contraindicated in (nausea), vomiting, avoid driving or
of a natural and chronic patients with: heartburn, operating
Brand Name: chemical called treatment of the Hypersensitivity to indigestion, machinery while
Arcoxia cyclo-oxygenase-2 signs and any component of uncomfortable taking drug
(COX-2) enzyme. symptoms of this product. feeling or pain in
Classification: This enzyme helps osteoarthritis (OA) >Congestive heart the stomach, > Assess client for
elective COX-2 to make other and rheumatoid failure (NYHA II-IV). diarrhea, swelling history of allergic
inhibitors chemicals, called arthritis (RA). >Established of the legs, ankles reaction to Arcoxia
prostaglandins, in >Treatment of ischemic heart or feet, high blood or for previous
the body. Some ankylosing disease, peripheral pressure, dizziness, heart conditions
prostaglandins are spondylitis (AS). arterial disease headache
produced at sites of >Treatment of and/or >Monitor blood
injury or damage, acute gouty cerebrovascular pressure regularly
and cause pain and arthritis. disease (including while taking this
inflammation >Treatment of patients who have medication.
acute pain, recently undergone
including that coronary artery > Arcoxia may be
related to primary bypass graft taken regardless of
dysmenorrhea and surgery or food intake. Stop
minor dental angioplasty). the medication
procedures. >Patients with immediately if
hypertension gastrointestinal
whose blood lesions occur.
pressure has not
been adequately
controlled.
Pregnancy.

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