DRUG STUDY

Generic Name Classification and Indication Mechanism of Contraindications Side effects Nursing Considerations
carvedilol Category action
Treatment of Hypersensitivity to Frequent (6%– Baseline assessment
Brand Name A. Chemical: Beta- mild to severe Possesses carvedilol. Bronchial 4%): Fatigue, Obtain B/P, apical pulse
Coreg adrenergic blocker. HF, left nonselective asthma or related dizziness. immediately before each
ventricular beta-blocking bronchospastic dose, in addition to regular
Available dosage
B. Therapeutic: dysfunction and alpha- conditions, cardiogenic Occasional (2%): monitoring (be alert to
 Tablets Antihypertensive. following MI, adrenergic shock, decompensated Diarrhea, fluctuations). Question for
(Immediate- hypertension blocking HF requiring bradycardia, possibility of pregnancy.
Release): 3.125 C. Pregnancy: Not activity. intravenous inotropic rhinitis, back pain. Assess medication history
mg, 6.25 mg, 12.5 assigned Causes therapy, severe hepatic (esp. diuretics).
mg, 25 mg. vasodilation. impairment, second- or Rare (less than
 Capsules third-degree AV block, 2%): Orthostatic Intervention/evaluation
(Extended- Therapeutic severe bradycardia, or hypotension, Maintain hydration (offer
Release [Coreg Effect: sick sinus syndrome drowsiness, UTI, fluids frequently). Assess
CR]): 10 mg, 20 Hypertension: (except in pts with viral infection. for evidence of upper
mg, 40 mg, 80 Reduces cardiac pacemaker). Cautions: respiratory infection,
mg. output, exercise- Diabetes, myasthenia cough. Monitor B/P, pulse.
induced gravis, mild to Assist with ambulation if
Route PO tachycardia, moderate hepatic dizziness occurs. Monitor
Frequency OD reflex orthostatic impairment. Withdraw daily pattern of bowel
Adverse
tachycardia; gradually to avoid acute activity, stool consistency.
Pharmacokinetics Reactions
reduces tachycardia,
 Onset: 30mins peripheral hypertension,
 Peak: 1-2hrs Potential for
vascular and/or ischemia. Pts
 Duration: 24hrs cataracts,
resistance. HF: suspected of having
 Half-life: 7-10hrs photosensitivity,
Decreases Prinzmetal’s angina, myalgia,
pulmonary pheochromocytoma, hx rhabdomyolysis.
capillary wedge of severe anaphylaxis to
pressure, heart allergens.
rate, systemic
vascular
resistance;
increases stroke
volume index.