DRUG NAME DOSAGE & MECHANISM OF ACTION INDICATION CONTRAINDICATION SIDE EFFECTS/ ADVERSE NURSING RESPONSIBILITY ROUTE REACTIONS Acts by selectively CNS: Headache,ataxia, Monitor vital signs. HR is a blocking all muscarinic -Adjunct in - Hypersensitivity to dizziness, excitement, sensitive indicator of patient's ATROPINE SULFATE responses to acetylcholine symptomatic belladonna alkaloids; irritability, convulsions, response to atropine. (a'troe-peen) (ACh), whether excitatory treatment of GI synechiae; angle- drowsiness, fatigue, • Initial paradoxical bradycardia Atropair , Atropisol, orinhibitory. Selective disorders and closure glaucoma; weakness; mental following IV atropine usually lasts Isopto Atropine depression of CNS spastic disorders of parotitis; obstructive depression, confusion, only 1–2 min; it most likely occurs relieves rigidity and biliary tract. Relaxes uropathy, e.g., bladder disorientation, when IV is administered slowly Classifications: tremor of Parkinson's upper GI tract and neck obstruction hallucinations. (more than 1 min) or when small AUTONOMIC NERVOUS syndrome. colon during caused by prostatic CV: Hypertension or doses (less than 0.5 mg) are used. SYSTEM AGENT; Antisecretory action hypotonic hypertrophy; intestinal hypotension, Postural hypotension occurs when ANTICHOLINERGIC (vagolytic effect) radiography. atony, paralytic ileus, ventricular tachycardia, patient ambulates too soon (PARA- suppresses sweating, Preoperative Use:To obstructive diseases of palpitation, paradoxical after parenteral administration. SYMPATHOLYTIC); lacrimation, salivation, suppress salivation, GI tract, severe bradycardia, AV dissociation, • Note: Frequent and continued ANTIMUSCARINIC and secretions from perspiration, and ulcerative colitis, toxic atrial or use of eye preparations, as well as nose, mouth, pharynx, respiratory tract megacolon; tachycardia ventricular fibrillation. overdosage, can have systemic and bronchi. Blocks secretions; to reduce secondary to cardiac GI: Dry mouth with effects. Some atropine deaths vagal impulses to heart incidence of insufficiency or thirst, dysphagia, loss have resulted from systemic with resulting decrease laryngospasm, reflex thyrotoxicosis; acute of taste; nausea, absorption following ocular in AV conduction time, bradycardia hemorrhage; myasthenia vomiting, constipation, administration in infants and increase in heart rate arrhythmia, and gravis. delayed gastric children. and cardiac output, and hypotension during Safety during emptying, antral stasis, Monitor I&O, especially in shortened PR interval. general anesthesia. pregnancy (category C) paralytic ileus. older adults and patients who or lactation is not Urogenital:Urinary have had surgery (drug may established. hesitancy and contribute to urinary retention). retention, dysuria, Palpate lower abdomen for impotence. distention. Have patient void Skin: Flushed, dry skin; anhidrosis, rash, urticaria, contact dermatitis, allergic conjunctivitis, fixed- drug eruption.